Kodi miyendo ndi nkhope yanu zikusintha pang'onopang'ono mawonekedwe ake ndikukula? Tiyeni tikambirane za Acromegaly.

Kodi munayamba mwamvapo ngati kukula kwa nsapato zanu kukukulirakulira, kapena kuti mphete yomwe munkavala kale yakhala ikumatirira pa chala chanu? Mwina mawonekedwe a nkhope yanu amaoneka mosiyana pang'ono mukayang'ana zithunzi zakale? Zambiri mwa izi zimachitika pakapita nthawi, nthawi zina kwa zaka zambiri, kotero sitimaziganizira kwambiri. Koma izi zitha kukhala chizindikiro cha matenda osowa otchedwa Acromegaly . Musadandaule, tidzakambirana chilichonse mwachidule.

Mwachidule, kodi Acromegaly ndi chiyani?

Acromegaly ndi vuto lomwe limayamba chifukwa chakuti thupi lathu limapanga mahomoni ochulukirapo okulitsa, kapena Growth Hormone (GH) . Homoni iyi imatithandiza kukula tili ana. Komabe, ngati mahomoniwa akupitiriza kutuluka titamaliza kukula, ndiko kuti, titakhala akuluakulu, ziwalo zina za thupi lathu, makamaka mafupa a manja, miyendo, ndi nkhope, zimayamba kukula kwambiri modabwitsa.

Matendawa nthawi zambiri amapezeka mwa anthu azaka zapakati. Koma izi sizikutanthauza kuti samachitika mwa achinyamata. Ngati mahomoni okula awonjezeka motere ali aang'ono, matendawa amatchedwa gigantism. Kenako amakula modabwitsa.

Acromegaly si vuto la kutalika kwambiri, koma kusintha kwa mawonekedwe a mafupa omwe akukula kale. Chifukwa chakuti kusintha kumeneku kumachitika pang'onopang'ono, sikungadziwike ngati vuto lachipatala kwa zaka zambiri.

Kodi nchifukwa chiyani acromegaly imayamba? Kodi zimayambitsa chiyani?

Chifukwa chachikulu cha izi ndi kachiwalo kakang'ono kamene kali ngati nandolo pansi pa ubongo wathu. Timakatcha kuti Pituitary Gland . Choyambitsa kwambiri cha Acromegaly ndi chotupa chosakhala khansa (chosavulaza) mu kachiwalo kameneka. Chotupachi chimatchedwa Pituitary Adenoma . Chotupachi chimalimbikitsa kachiwalo ka pituitary ndipo chimapanga mahomoni ochulukirapo (GH).

Homoni ya GH yochulukirapoyi imasonkhana m'magazi athu ndipo imauza chiwindi kuti chipange homoni ina yotchedwa IGF-1 (Insulin-like Growth Factor-1) . Homoni ya IGF-1 imeneyo ndi yomwe imapangitsa mafupa athu ndi ziwalo zina kukula modabwitsa. Imakhudzanso momwe thupi lathu limalamulira shuga ndi mafuta, zomwe zimawonjezera chiopsezo chotenga matenda ena.

Kawirikawiri, vutoli lingayambitsidwenso ndi zotupa zomwe zimapezeka m'mbali zina za kapamba, chiwindi, kapena ubongo. Kafukufuku wapeza kuti zinthu zina za majini nazonso zingayambitse vutoli.

Kodi zizindikiro za acromegaly ndi ziti?

Zizindikiro zimenezi nthawi zambiri zimawonekera pang'onopang'ono, kotero zingatenge nthawi kuti muzindikire kusiyana.

Kodi mungazindikire bwanji matendawa?

Ndikofunikira kuzindikira vutoli mwachangu. Mukapita kwa dokotala chifukwa cha zizindikiro izi, adzakufunsani mafunso monga:

• Ndi kusintha kotani komwe mukuona?
• Kodi munayamba liti kuzindikira kusintha kumeneku?
• Mukumva bwanji tsopano?

Kenako, mayeso angapo amachitidwa kuti atsimikizire matendawa.

Mayeso akuluakulu

• Kuyezetsa magazi: Kuyezetsa magazi kumachitika kuti muwone ngati kuchuluka kwa mahomoni anu a IGF-1 kwakwera malinga ndi msinkhu wanu.
• Mayeso Ololera Shuga: Apa, mumapatsidwa chakumwa chokhala ndi shuga ndipo shuga m'magazi mwanu ndi mahomoni a GH zimayesedwa kwa maola awiri. Kawirikawiri, milingo ya GH iyenera kutsika mutamwa shuga. Ngati sichoncho, ndipo ikadali yokwera, ndi chizindikiro cha acromegaly.

Mayeso ena

• MRI kapena CT scan: Ma scan amenewa amathandiza kuzindikira chotupa cha pituitary.
• Mayeso a X-ray: Yang'anani ngati mafupa akukhuthala.
• Echocardiogram: Kuyesa mtima pogwiritsa ntchito ultrasound kuti muwone ngati mtima wakhudzidwa.
• Colonoscopy: Kuyang'ana thanzi la m'matumbo.
• Kuphunzira za Kugona: Onani ngati muli ndi vuto la Sleep Apnea.

Kodi mankhwala ake ndi otani?

Dokotala wanu adzakukonzerani njira yoyenera kwambiri yochizira matenda anu kutengera zaka zanu, thanzi lanu, komanso kuopsa kwa matenda anu. Pali njira zitatu zazikulu zochizira.

1. Opaleshoni:

Kawirikawiri, chithandizo choyamba ndi opaleshoni yochotsa chotupa cha pituitary. Izi ndizofunikira kwambiri ngati chotupacho chikukankhira mitsempha yomwe imakhudza masomphenya. Dokotalayo amachotsa chotupacho kudzera mu kudula pang'ono kudzera mu mphuno kapena mkati mwa mlomo wapamwamba. Zizindikiro zimatha kuyamba kusintha pakatha masiku angapo opaleshoni itatha.

2. Mankhwala:

Ngati pali zidutswa zina zotsala za chotupacho mutachita opaleshoni kapena ngati mukufuna thandizo lowonjezera pakuwongolera kuchuluka kwa mahomoni anu, dokotala wanu adzakupatsani mankhwala. Mankhwalawa amachepetsa kuchuluka kwa GH kapena kuletsa zotsatira zake pa thupi.

• Ma analogue a Somatostatin (monga lanreotide, octreotide)
• Otsutsa kukula kwa mahomoni (monga pegvisomant)
• Mankhwala a dopamine agonists (monga cabergoline)

3. Chithandizo cha Radiation:

Ngati pali mbali zina za chotupacho zitatsala pambuyo pa opaleshoni ndi mankhwala, kapena ngati milingo ya GH ikufunika kuchepetsedwa kwambiri, chithandizo cha radiation chimagwiritsidwa ntchito. Izi zimaletsa chotupacho kukula ndipo zimachepetsa kupanga kwa GH. Njira zamakono monga stereotactic radiosurgery zimatha kupereka radiation yambiri ku chotupacho popanda kuwononga minofu yathanzi.

Mavuto omwe angachitike ngati sanalandire chithandizo

Acromegaly ingayambitse mavuto aakulu azaumoyo ngati sichithandizidwe bwino, choncho musanyalanyaze vutoli.

• Matenda a mtima
• Matenda a shuga
• Kuthamanga kwa magazi
• Matenda a nyamakazi (Osteoarthritis)
• Matenda a Carpal Tunnel
• Kulephera Kugona Bwino
• Kutaya masomphenya
• Kuwonjezeka kwa chiopsezo cha khansa ya m'matumbo
• Kupsinjika kwa mitsempha ya msana

Matendawa akhoza kukhala oopsa ngati sachiritsidwa, choncho ndikofunika kupeza upangiri wa dokotala nthawi yomweyo ngati muli ndi zizindikiro.