Kugwirizana Pakati pa Matenda a Shuga ndi Matenda a Alzheimer: Tiyeni Tikambirane za Matenda a Shuga a 'Mtundu Wachitatu'

Ambiri a ife tikamva mawu akuti matenda a shuga, timawaona ngati matenda omwe amakhudza kuchuluka kwa shuga m'thupi, mtima, impso, ndi maso. Ndi zoona. Koma kodi mukudziwa, kafukufuku waposachedwapa wapeza kuti matenda a shuga angakhudzenso ubongo wathu ndi kukumbukira kwathu mwachindunji. Madokotala ena akugwiritsa ntchito dzina latsopano la matenda awa, lomwe ndi 'Type 3 Diabetes'. Chifukwa chake lero, tiyeni tikambirane za izi.

Kodi matenda a shuga a 'Mtundu wachitatu' kwenikweni ndi chiyani?

Mwachidule, 'Mtundu wachitatu wa matenda a shuga' ndi dzina lomwe akatswiri ena apereka chifukwa cha matenda a Alzheimer. Chifukwa chake ndi chakuti amakhulupirira kuti chifukwa chachikulu cha mitundu ina ya matenda a Alzheimer ndi kuwonongeka komwe matenda a shuga angayambitse ku ubongo pakapita nthawi.

Kwa nthawi yayitali, asayansi ankaganiza kuti mahomoni a insulin alibe chochita ndi ntchito ya ubongo. Koma tsopano tikudziwa kuti sizili choncho. Insulin imayendanso kupita ku maselo athu a ubongo. Ndipo insulin iyi ndi yofunika kwambiri pa kuganiza ndi kukumbukira kwathu.

Kotero, ubongo wanu ukapanda kulandira insulin yokwanira, kapena ukalephera kugwiritsa ntchito insulin, umalandira bwino (tikutcha kuti insulin resistance), ntchito ya tsiku ndi tsiku ya maselo a ubongo imayamba kuchepa. Izi ndi zomwe zimachitika mu matenda a Alzheimer's.

N’chifukwa chiyani izi zikuchitika? Kodi zifukwa zake ndi ziti?

Kafukufuku wasonyeza momveka bwino kuti anthu omwe ali ndi matenda a shuga asanafike nthawi yobereka kapena matenda a shuga a mtundu wachiwiri ali pachiwopsezo chachikulu chotenga matenda a Alzheimer's ndi matenda ena a dementia akadzakula. Izi zimachitika chifukwa cha zinthu zingapo.

1. Kuwonongeka ndi kutupa kwa mitsempha yamagazi

Matenda a shuga amawonjezera chiopsezo cha matenda a mtima ndi sitiroko. Komanso, shuga m'magazi akakwera, kutupa kumachitika m'thupi. Izi sizothandiza pa mitsempha yathu yamagazi. Pamene mitsempha yofewa yamagazi muubongo yawonongeka mwanjira imeneyi, zimatha kuyambitsa matenda a Alzheimer's.

2. Kusokonezeka kwa kulumikizana pakati pa maselo a mitsempha

Shuga ikakwera m'magazi, ma protein ambiri otchedwa beta-amyloid amasonkhana muubongo. Ma protein ambiriwa amasonkhana pamodzi ndipo amakakamira pakati pa maselo amitsempha muubongo. Monga momwe magalimoto ambiri amachitikira pamsewu, ma protein ambiriwa amaletsa ma neurons kulankhulana. Ichi ndi chizindikiro chachikulu cha matenda a Alzheimer's.

3. Kugwirana kwa puloteni ya Tau

Tangoganizani kuti ubongo wathu uli ndi njira ya machubu ang'onoang'ono (microtubules) omwe amanyamula zakudya m'maselo a mitsempha. Puloteni yotchedwa tau imagwira ntchito ngati 'woteteza' kuti machubuwa akhale bwino komanso kuti asasocheretsedwe. Mu ubongo wa munthu amene ali ndi matenda a Alzheimer's, puloteni iyi ya tau imasokonekera. Kenako njira ya machubu imatsekedwa, maselo sangathe kunyamula zomwe akufuna, ndipo maselo amafa. Kafukufuku wina wapeza kuti pali mapuloteni ambiri a tau osokonezeka mu ubongo wa anthu odwala matenda ashuga.

4. Kukana kwa insulin

Uwu ndiye maziko a lingaliro la 'Type 3 Diabetes'. Monga maselo m'thupi, pamene maselo a muubongo sayankha bwino ku insulin, maselo amenewo salandira mphamvu (mafuta) zomwe amafunikira. Kenako ntchito ya ubongo imasokonekera. Komanso, kukana insulini muubongo kumawonjezera vuto loopsa lotchedwa oxidative stress.

Kodi zizindikiro za vutoli zingakhale zotani?

Zizindikiro zokhudzana ndi lingaliro la 'Mtundu wachitatu wa Matenda a Shuga' zimafanana ndi za matenda a Alzheimer's. Izi zitha kuoneka kumayambiriro.

Tiyeni tiphunzire za matenda ndi chithandizo.

Monga tanenera kale, palibe matenda a shuga amtundu wachitatu omwe akupezeka, kotero dokotala sangathe kuchita mayeso kuti atsimikizire izi. Komabe, ngati muli ndi vuto la kukumbukira, dokotala wanu adzakuyezani ngati muli ndi vuto la matenda amisala.

Izi zingaphatikizepo mafunso okhudza momwe munthu alili m'maganizo, kufufuza ubongo (MRI kapena CT scans), komanso nthawi zina kuyesa madzi a msana.

Ponena za chithandizo, palibe chithandizo chapadera cha 'Type 3 Diabetes'. Koma pali zinthu ziwiri zofunika kwambiri zomwe mungachite:

1. Ngati muli ndi matenda a shuga, samalani bwino. Ndikofunikira kugwiritsa ntchito mankhwala omwe dokotala wanu wakupatsani molondola komanso kuwongolera kuchuluka kwa shuga m'magazi mwanu.

2. Pezani mankhwala a matenda a Alzheimer omwe alipo panopa. Ngakhale kuti mankhwala amenewa sangachiritse matendawa kotheratu, angathandize kuchepetsa kuchuluka kwa zizindikiro zomwe zimakula.

Kafukufuku wina wasonyezanso kuti mankhwala ena a matenda a shuga, monga metformin ndi pioglitazone, angachepetse chiopsezo cha matenda a dementia mtsogolo. Kafukufuku wina akupitirira.

Kodi mungateteze bwanji thanzi la ubongo wanu ndikuchepetsa chiopsezochi?

Kuti tipewe ngozi imeneyi, pali zinthu zofunika kwambiri zomwe tingawonjezere pa moyo wathu. Izi ndi zabwino kwambiri pa thanzi la ubongo wanu, komanso thupi lanu lonse.

• Khalani otanganidwa: Chitani masewera olimbitsa thupi kwa mphindi 30 patsiku, masiku osachepera 5 pa sabata. Sankhani chinthu chomwe mumakonda. Chingakhale kuyenda, kuvina, kapena kukwera njinga.
• Pewani kusuta: Ngati mukusuta, funsani dokotala wanu kuti akuthandizeni kusiya kusuta.
• Khalani ndi thupi labwino: Idyani zipatso zambiri, ndiwo zamasamba, tirigu wonse (monga mpunga wofiirira), nyama yopanda mafuta ambiri, ndi mkaka wopanda mafuta ambiri. Chepetsani shuga ndi mafuta okhuta.
• Samalani kuthamanga kwa magazi anu: Ngati dokotala wanu wakupatsani mankhwala, imwani monga momwe mwalangizidwira.
• Gonani bwino: Yesetsani kugona bwino kwa maola 7-8 tsiku lililonse.
• Khalani ndi anthu ena: Khalani ndi nthawi yocheza ndi anzanu komanso abale anu. Kusungulumwa komanso kudzipatula sikwabwino ku ubongo.
• Phunzirani zinthu zatsopano: Zinthu monga kuphunzira chinenero chatsopano, chida choimbira, kapena kuthetsa ma puzzles zimamanga mgwirizano watsopano pakati pa maselo a ubongo.