Bisphosphonates: Tiyeni tiphunzire za mankhwala awa omwe amalimbitsa mafupa anu.

Kodi dokotala wanu wakuuzani kuti mafupa anu ndi ofooka pang'ono, kutanthauza kuti muli ndi matenda a osteoporosis, matenda ochepetsa mafupa? Mwina wakuuzani kuti muyambe kumwa mankhwala otchedwa bisphosphonate. Mukamva dzinali, mungakhale ndi mantha pang'ono, mukudabwa kuti, "Mankhwalawa ndi chiyani? Adzagwira ntchito yanji?" Musachite mantha. Lero, tikambirana za mtundu uwu wa mankhwala omwe angathandize kulimbitsa mafupa anu m'njira yosavuta, m'njira yomwe mungamvetse.

Mwachidule, kodi ma bisphosphonates awa ndi chiyani?

Ma bisphosphonates ndi gulu lalikulu la mankhwala omwe amagwiritsidwa ntchito pochiza matenda a osteoporosis. Tangoganizani kuti mafupa anu amafooka pang'onopang'ono pakapita nthawi, ngati chidutswa cha mtengo chomwe chadyedwa ndi tizilombo. Kenako, ngakhale kugwa pang'ono kumawonjezera chiopsezo chosweka mafupa anu. Matenda a osteoporosis ndi vuto limenelo. Chifukwa chake, ma bisphosphonates amaletsa mafupa anu kufooka kwambiri, kuwapangitsa kukhala olimba, ndikuchepetsa chiopsezo chosweka.

Madokotala amapereka mankhwalawa osati kokha kwa osteoporosis, komanso matenda ena angapo omwe amakhudza kuchuluka kwa mafupa, komanso nthawi zina calcium yambiri m'magazi (hypercalcemia).

Kodi mankhwala awa alipo? Tiyeni tiwone.

Inde, pali mitundu iwiri ya ma bisphosphonates.

1. Ma bisphosphonates omwa

2. Jakisoni mu mtsempha (IV bisphosphonates)

Dokotala adzafufuza matenda anu ndikusankha mtundu womwe uli woyenera kwa inu.

Kodi ma bisphosphonates amagwiritsidwa ntchito pa matenda otani?

Mankhwalawa amavomerezedwa makamaka kuti athetse mavuto awa:

• Matenda a mafupa (osteoporosis) mwa akazi omwe asiya kusamba.
• Matenda a mafupa mwa amuna.
• Kupewa kuonda mafupa.
• Matenda a osteoporosis omwe amayambitsidwa ndi glucocorticoid amayamba chifukwa chogwiritsa ntchito mankhwala ena a steroid kwa nthawi yayitali.
• Khansa zina zimayambitsa kuchuluka kwa calcium m'magazi (cancer-related hypercalcemia).
• Matenda a Paget a mafupa ndi matenda omwe amakhudza mafupa.
• Matenda a khansa otchedwa multiple myeloma.
• Pa milandu yomwe khansa yomwe inayambira kwina yafalikira (yafalikira) mpaka mafupa.

Nthawi zina, madokotala amagwiritsa ntchito mankhwalawa pa matenda ena osati omwe amavomerezedwa. Mwachitsanzo, nthawi zina amaperekedwa kwa ana ndi akuluakulu omwe ali ndi vuto la majini lotchedwa osteogenesis imperfecta .

Kodi mankhwalawa amagwira ntchito bwanji m'thupi?

Kuti timvetse izi, choyamba tiyenera kudziwa pang'ono za mafupa athu. Mafupa athu samangokhala pamalo amodzi okha. Amasinthidwa nthawi zonse. Monga khoma lomwe njerwa zakale zimachotsedwa ndipo zatsopano zimamangidwa. Thupi limasweka mwachibadwa ndikuchotsa fupa lakale. Izi timazitcha kuti kusungunula mafupa. Kenako fupa latsopano limapangidwa m'malo amenewo.

Pamene tikukalamba, makamaka mwa akazi akatha kusamba, njirayi imakhala yosakhazikika. Izi zikutanthauza kuti, fupa lakale limayamba kusweka ndikuchotsedwa mwachangu kuposa momwe fupa latsopano limapangidwira. Pamenepo ndi pomwe mafupa amayamba kufooka pang'onopang'ono komanso kuchepa kwa minofu, zomwe zimapangitsa kuti mafupa asamathenso kufooka.

Kodi ndingagwiritse ntchito bwanji mankhwalawa? Izi ndizofunikira kwambiri!

Njira yogwiritsira ntchito imasiyana malinga ndi mtundu wa mankhwala omwe mumalandira.

Ngati mapiritsi atengedwa pakamwa...

Iyi ndi gawo lomwe muyenera kusamala kwambiri . Dokotala adzakuuzani kuti mumwe mapiritsi awa kamodzi patsiku, kamodzi pa sabata, kapena kamodzi pamwezi. Komabe, muyenera kumwa mapiritsi awa.Pali njira yapadera .

• Muyenera kumwa piritsili mukangodzuka m'mawa, musanadye kapena kumwa china chilichonse .
• Piritsi liyenera kumwedwa ndi galasi lodzaza la madzi wamba . Ndikoletsedwa kumwa piritsili ndi tiyi, khofi, mkaka, kapena zakumwa za zipatso.
• Mukatha kumwa mapiritsi, musagone kapena kugona kwa mphindi zosachepera 30 (mwina mphindi 60). Muyenera kukhala pansi kapena kuimirira molunjika.
• Komanso, simungamwe chakudya china chilichonse, chakumwa, kapena mankhwala ena aliwonse mkati mwa mphindi 30-60 izi.

Ndikofunikira kutsatira malamulo awa molondola. Kupanda kutero, mankhwalawo sangalowe bwino m'thupi ndipo angayambitse ziwengo pakhosi ndi m'mimba. Dokotala wanu adzakufotokozerani izi mwatsatanetsatane.

Ngati ndi jakisoni wa mtsempha...

Kawirikawiri katemerayu amaperekedwa kwa inu kuchipatala kapena ku chipatala. Nthawi zambiri, katemerayu amaperekedwa kamodzi pachaka . Komabe, kutengera ndi momwe alili, angaperekedwe pafupipafupi.

Kodi mukufuna kuchita zinthu zina ndi mankhwalawo?

Inde. Dokotala wanu nthawi zambiri amalangiza zotsatirazi mukamamwa mankhwalawa:

• Idyani zakudya zokhala ndi calcium yambiri (monga mkaka, yogurt, tchizi, nsomba zazing'ono, ndiwo zamasamba zobiriwira)
• Ngati muli ndi vuto la vitamini D, tengani mankhwala owonjezera a vitamini D.
• Ngati simukupeza calcium yokwanira kuchokera ku chakudya, imwani mapiritsi a calcium .

Ndiyenera kumwa mankhwalawa kwa nthawi yayitali bwanji?

Izi zimadalira momwe thupi lanu limayankhira mankhwalawo. Nthawi zambiri, madokotala amachepetsa nthawi yogwiritsira ntchito mapiritsi akumwa kwa zaka pafupifupi 5 ndipo jakisoni wa zoledronic acid m'mitsempha yamagazi kwa zaka pafupifupi 3. Izi zimatetezani ku zotsatira zoyipa zomwe zingachitike mukagwiritsa ntchito mankhwalawa kwa nthawi yayitali. Komabe, anthu ena angafunike kulandira chithandizo kwa nthawi yayitali. Dokotala wanu ndiye munthu woyenera kusankha.

Tiyeni tiphunzirenso za zotsatirapo zake.

Monga mankhwala ena aliwonse, bisphosphonates ingayambitse zotsatirapo zoyipa, koma si aliyense amene amalandira.

Kodi mankhwalawa ndi othandizadi?

Inde, ndithudi. Kafukufuku wasonyeza kuti mankhwalawa amawonjezera kuchulukana kwa mafupa ndipo amachepetsa kwambiri chiopsezo cha kusweka kwa mafupa.

• Alendronate: Imachepetsa kusweka kwa msana ndi pafupifupi 50% ndipo imachepetsa kusweka kwa chiuno ndi zina ndi pafupifupi 30%.
• Risedronate: Amachepetsa kusweka kwa msana ndi ziwalo zina ndi pafupifupi 40%.
• Zoledronic acid: Imachepetsa kusweka kwa msana ndi pafupifupi 70% ndipo imachepetsa kusweka kwa chiuno ndi zina ndi pafupifupi 35%.

Ndiyenera kupita kwa dokotala liti?

Ngati mumwa mankhwala awa, chitani zomwe dokotala wakuuzani.Ndikofunikira kwambiri kupita kuzipatala nthawi yake. Izi zitithandiza kuona ngati mankhwalawo akugwira ntchito komanso ngati pali zotsatirapo zina. Dokotala wanu angakulimbikitseninso kuti mupange DXA scan, yomwe imayesa kuchuluka kwa mafupa anu.

Kumbukirani makamaka:

Mankhwalawa ndi mankhwala ofunikira kwambiri omwe angakuthandizeni kukhala ndi moyo wabwino komanso kukutetezani ku mavuto aakulu omwe angabwere chifukwa cha kusweka kwa fupa. Ngati muli ndi mafunso kapena nkhawa zokhudzana ndi izi, onetsetsani kuti mwakambirana momasuka ndi dokotala wanu.