Kodi mukudziwa za khansa ya impso (RMC), khansa yosowa koma yoopsa yomwe imayamba m'impso?

Kodi mudamvapo za khansa yowopsa komanso yosowa kwambiri yomwe imayamba mu impso, makamaka mwa achinyamata? Mwina ayi. Iyi ndi Renal Medullary Carcinoma, kapena RMC mwachidule. Ngakhale kuti si yofala kwambiri, kungakhale kofunikira kudziwa za khansayi, makamaka kwa anthu ena. Ngakhale kuti nkhaniyi ndi yofunika kwambiri, musachite mantha. Tiyeni tikambirane za khansayi m'njira yosavuta komanso yomveka bwino lero.

Kodi RMC kwenikweni ndi chiyani?

Mwachidule, khansa ya impso yotchedwa Renal Medullary Carcinoma (RMC) ndi mtundu wa khansa ya impso. Koma ndi yosowa kwambiri, yoopsa kwambiri, ndipo imafalikira mofulumira. Imapezeka kwambiri mwa achinyamata, makamaka omwe ali ndi vuto la magazi lotchedwa sickle cell disease kapena sickle cell trait.

Tikamalankhula za khansa ya impso, mtundu wofala kwambiri ndi renal cell carcinoma. RMC ndi mtundu wina wa renal cell carcinoma. Koma palibe ngakhale m'modzi mwa odwala 100 omwe ali ndi khansa ya impso amene ali ndi vutoli. Ndi losowa kwambiri.

Kodi n’chiyani chimayambitsa khansa imeneyi?

Asayansi ndi madokotala sanapezebe chifukwa chenicheni cha izi 100%, koma pali chinthu chimodzi chachikulu chomwe chadziwika.

Impso zathu zili ndi gawo lotchedwa renal medulla. Munthu amene ali ndi vuto la sickle cell nthawi zina amakhala ndi maselo ofiira a magazi omwe amasintha kukhala mawonekedwe a sickle. Izi zikachitika, maselo amatha kumamatirana ndikutseka mitsempha yamagazi yomwe ili mu gawo la renal medulla la impso.

Kutsekeka kwa magazi kumeneku kumawononga maselo omwe ali m'derali. Makamaka, jini yotchedwa INI1 (yomwe imatchedwanso SMARCB1) m'maselo amenewo imawonongeka. Jini iyi ya INI1 imagwira ntchito ngati woteteza yomwe imaletsa maselo kuti asachite khansa. Maselo a khansa ya RMC akafufuzidwa, jini iyi ya INI1 sipezeka mwa iwo. Chifukwa chake madokotala amafufuza ngati pali jini iyi ya INI1 kuti atsimikizire ngati chotupa ndi RMC kapena ayi.

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Kodi inenso ndili pachiwopsezo chotenga RMC?

N'zovuta kunena bwino lomwe amene angadwale matendawa. Kukhala ndi munthu m'banja mwanu amene ali ndi RMC sikukuwonjezera chiopsezo chanu chodwala matendawa. Izi zikutanthauza kuti si chinthu chomwe chimachitika m'mabanja.

Choopsa chachikulu ndi matenda a magazi otchedwa sickle hemoglobinopathy. Ndiko kuti, kukhala ndi sickle cell disease kapena sickle cell trait. Koma nthawi zambiri , anthu opanda matendawa amathanso kukhala ndi RMC. Imatchedwa "renal cell carcinoma, yosagawidwa ndi medullary phenotype" (RCCU-MP).

Ngati muyang'ana ziwerengero:

• Kawirikawiri mwa amuna kuposa akazi.
• Kawirikawiri zimakhudza impso yoyenera.
• Matendawa nthawi zambiri amapezeka ali aang'ono, azaka zapakati pa 11 ndi 39.

Ndikofunikira kuti achinyamata, makamaka omwe ali ndi matenda a sickle cell kapena sickle cell trailing, adziwe zizindikirozi, chifukwa kuzizindikira msanga kungathandize kuti chithandizo chikhale chosavuta. Ngati zizindikiro zikupezeka, pitani kwa dokotala nthawi yomweyo.

Kodi zizindikiro za RMC ndi ziti?

Pali zizindikiro zingapo zodziwika bwino za matendawa. Ngati muli ndi chimodzi kapena zingapo mwa izi, ndi bwino kupeza upangiri wa dokotala mwachangu momwe mungathere.

Kodi dokotala amazindikira bwanji izi?

Mukatiuza za zizindikiro zanu, chinthu choyamba chomwe dokotala angachite ndikukufufuzani. Kenako mutha kutsatira njira izi.

1.Kujambula kwa Ultrasound: Izi zingapereke chithunzithunzi chokwanira cha ngati pali chotupa mu impso.

2. Kujambula kwa CT kapena MRI: Ngati mukukayikira kuti pali chotupa, CT scan kapena MRI ikhoza kuyitanidwa kuti ipeze chithunzi chomveka bwino cha chotupacho. Kutengera ndi zithunzi izi, dokotala akhoza kudziwa momwe chingakhalire ndi khansa.

3. Kufufuza kwa khansa: Ngati mukukayikira kwambiri kuti muli ndi khansa, mayesowa amachitika kuti atsimikizire izi. Izi zimaphatikizapo kulowetsa singano yaying'ono m'dera la chotupa cha impso, kutenga chidutswa chaching'ono kwambiri cha minofu ndikuchiyang'ana pansi pa maikulosikopu.

4. Kuyesa majini: Maselo otengedwa kuchokera ku biopsy amawunikidwa kuti awone ngati ali ndi jini ya INI1 yolimbana ndi khansa yomwe tidakambirana kale.

• Ngati jini ya INI1 ikusowa , imadziwika kuti ndi RMC.
• Ngati jini ya INI1 palibe ndipo wodwalayo alibe vuto la sickle cell, amapezeka kuti ndi RCCU-MP.
• Ngati jini ya INI1 ilipo , si RMC, koma mtundu wina wa chotupa.

Kodi mankhwala ochizira izi ndi otani?

Popeza RMC ndi khansa yofala mofulumira komanso yoopsa, chithandizo chiyenera kuchitika mwachangu komanso mwamphamvu mofanana.

• Chemotherapy: Iyi ndi njira yoyamba yodziwika kwambiri yochizira. Imaphatikizapo kupatsa thupi mankhwala omwe amapha maselo a khansa.
• Opaleshoni: Kuchotsa chotupa cha khansa komanso mwina impso yomwe yakhudzidwa.
• Chithandizo cha Radiation: Kuwononga maselo a khansa pogwiritsa ntchito kuwala kwamphamvu kwa radiation.

Popeza matendawa ndi osowa, kafukufuku akupitirirabe. Asayansi nthawi zonse amafunafuna njira zatsopano komanso zothandiza kwambiri zochizira RMC.

Kodi pali njira yopewera RMC?

Mwatsoka, pakadali pano palibe njira yodziwika yopewera RMC kuti isakule, komanso palibe njira yoyesera kuti izindikire zizindikiro zisanawonekere.

Chinthu chabwino chomwe mungachite ndikudziwa . Ngati mukudziwa kuti muli ndi matenda a sickle cell kapena vuto la sickle cell, yang'anani zizindikiro zomwe zatchulidwa pamwambapa. Ngati muli ndi nkhawa iliyonse, pitani kwa dokotala nthawi yomweyo.

Kawirikawiri, matendawa akapezeka, khansa imakhala itafalikira kale ku ma lymph nodes kapena ziwalo zina monga mapapo, chiwindi, ndi mafupa. Chifukwa chake, kuzindikira msanga ndiyo njira yabwino kwambiri yopezera zotsatira zabwino kwambiri.