Kodi thupi lanu likukulirakulira ndipo nkhope yanu ikuzungulira ngati mwezi wathunthu? Tiyeni tikambirane za 'Cushing's Syndrome'!

Kodi mwazindikira posachedwapa kuti mawonekedwe a thupi lanu asintha pang'ono, makamaka kuzungulira thupi lanu lakumwamba ndi m'mimba, ndipo nkhope yanu yakhala yozungulira ngati mwezi wathunthu? Mwina muli ndi kachidutswa kakang'ono ka mafuta komwe kakukula kumbuyo kwa khosi lanu. Izi si zinthu zosayembekezereka chabe. Kumbuyo kwa zizindikirozi kungakhale vuto la mahomoni lotchedwa Cushing's Syndrome . Musadandaule, ili ndi vuto lomwe nthawi zambiri lingachiritsidwe. Tiyeni tikambirane za izi mosavuta, mwanjira yomwe aliyense angamvetse.

Mwachidule, kodi Cushing's Syndrome ndi chiyani?

Matenda a Cushing, kapena hypercortisolism , ndi matenda omwe amachitika pamene thupi lathu limapanga mahomoni ambiri a cortisol . Tsopano mwina mukudabwa kuti cortisol ndi chiyani. Cortisol ndi mahomoni ofunikira kwambiri opangidwa ndi tiziwalo tiwiri tating'onoting'ono tomwe tili pamwamba pa impso zathu, ma adrenal glands. Imagwira ntchito zambiri m'thupi lathu.

• Amalamulira kuthamanga kwa magazi .
• Amachepetsa kuchuluka kwa shuga m'magazi.
• Amachepetsa kutupa m'thupi.
• Zimathandiza kusintha chakudya chomwe timadya kukhala mphamvu.

Tangoganizirani, zonsezi zimachitika pamene pali cortisol yokwanira. Koma pamene mahomoni awa achuluka kwambiri, kugwira ntchito kwa machitidwe ena m'thupi kumayamba kusokonekera. Ndicho chimene timachitcha Cushing's Syndrome. Matendawa amapezeka kwambiri mwa akazi kuposa amuna. Amafala kwambiri mwa anthu azaka zapakati pa 25 ndi 40.

Kodi zifukwa zazikulu za matenda a Cushing's Syndrome ndi ziti?

Pakhoza kukhala zifukwa zingapo za izi. Tiyeni tiwone zazikulu.

1. Kugwiritsa ntchito mankhwala (chifukwa chofala kwambiri)

Chomwe chimayambitsa vutoli nthawi zambiri ndi kugwiritsa ntchito mankhwala ambiri otchedwa glucocorticoids kwa nthawi yayitali. Mankhwalawa nthawi zambiri amatchedwa corticosteroids kapena ma steroids . Mwachitsanzo, prednisoneMutha kumwa mankhwala otchedwa. Madokotala amalimbikitsa mankhwala awa pa matenda monga mphumu, nyamakazi, lupus, kapena mutapatsidwa chiwalo. Awa ndi mankhwala amphamvu kwambiri omwe amaletsa kutupa. Komabe, akagwiritsidwa ntchito kwa nthawi yayitali, Cushing's Syndrome imatha kuchitika ngati zotsatira zoyipa. Komanso, vutoli likhoza kuchitika chifukwa cha jakisoni wa steroid wopitilira pazinthu monga kupweteka kwa mafupa ndi kupweteka kwa msana. Vutoli ndi losowa kwambiri chifukwa cha mafuta a steroid omwe amagwiritsidwa ntchito pa matenda a pakhungu, koma likhoza kuchitika.

2. Zotupa zomwe zimachitika m'thupi

Kuchuluka kwa cortisol kungawonjezerenso m'thupi lathu. Chifukwa cha izi ndi mitundu yosiyanasiyana ya zotupa zomwe zimakula m'thupi.

• Ziphuphu za Pituitary: Ngati chotupa chaching'ono chikayamba mu pituitary gland pansi pa ubongo wathu, chimayamba kupanga mahomoni ambiri otchedwa ACTH (Adrenocorticotropic hormone) . Homoni iyi ya ACTH ndiyo imauza ma adrenal glands kuti apange cortisol . Chifukwa chake ACTH ikachuluka, kupanga kwa cortisol kumawonjezekanso. Timatchanso vutoli kuti Matenda a Cushing .
• Ziphuphu za Adrenal: Nthawi zina chotupa chingayambike pa adrenal gland yokha, yomwe ingapangitse mwachindunji cortisol yochulukirapo.
• Ziphuphu za m'mimba: Nthawi zambiri, chotupa chimatha kupangika pamalo pomwe mahomoni a ACTH sapangidwa, monga mapapo , kapamba , kapena chithokomiro , ndikuyamba kupanga ACTH.

Zotupa zimenezi zitha kukhala za khansa kapena zosakhala za khansa.

Kodi zizindikiro za matendawa ndi ziti?

Zizindikiro zimatha kusiyana malinga ndi munthu, koma pali zizindikiro zina zomwe zimaonekera matendawa akakula. Tiyeni tiwone izi patebulo. Kuphatikiza apo, anthu ena amatha kuona zizindikiro zofiirira kapena pinki zotambasula m'mimba mwawo, ntchafu, m'manja, ndi pachifuwa. Pamene mafupa akufooka, amatha kumva kupweteka kwa msana kapena nthiti zosweka, osati pongowerama, kunyamula zolemera, komanso akamadzuka pampando. Ngati ana aang'ono akupeza vutoli, kukula kwawo kudzakhala pang'onopang'ono kwambiri, ndipo amathanso kunenepa kwambiri.

Kodi dokotala amazindikira bwanji matendawa?

Zingatenge maulendo angapo kuti dokotala wanu atsimikizire kuti muli ndi matendawa. Choyamba, adzakuyesani thupi lanu ndikukufunsani mafunso angapo.

• Kodi zizindikiro zanu ndi ziti?
• Kodi munayamba liti kuziona izi?
• Kodi mukumwa mankhwala otani? (Makamaka ma steroids)
• Kodi mukumva kusintha kwa maganizo anu?

Kutengera ndi izi, ngati akukayikira kuti Cushing's Syndrome ndi yoopsa, dokotalayo adzalangiza mayeso angapo.

• Mayeso a cortisol opanda mkodzo kwa maola 24: Amayesa kuchuluka kwa cortisol mu mkodzo womwe wasonkhanitsidwa kwa maola 24.
• Mayeso oletsa Dexamethasone: Piritsi lochepa la steroid limaperekedwa pafupifupi 11 koloko madzulo, ndipo mayeso a magazi amachitidwa m'mawa wotsatira kuti awone kuchuluka kwa cortisol yomwe thupi likupangabe.
• Mulingo wa cortisol m'malovu usiku: Amayesa kuchuluka kwa cortisol m'chitsanzo cha malovu chomwe chimatengedwa usiku.

Ngati mayesowa akutsimikizira kuti muli ndi Cushing's Syndrome, sitepe yotsatira ndikupeza chomwe chikuyambitsa . Kuti muchite izi, katswiri angachite mayeso ena angapo. Mwachitsanzo, mayeso a magazi kuti awone kuchuluka kwa mahomoni a ACTH, CT kapena MRI scans.

Kodi mankhwala ochizira izi ndi otani?

Njira yochizira imadalira chomwe chikuyambitsa vuto lanu.

• • Ngati chifukwa chake ndi mankhwala a steroid: Dokotala wanu ayamba kuchepetsa pang'onopang'ono mlingo wa steroid yanu pamene matenda ena omwe muli nawo (monga mphumu, nyamakazi) akuwongoleredwa.

Chofunika kwambiri: Musasiye kumwa mankhwala a steroid mwadzidzidzi popanda upangiri wa dokotala. Kuchita zimenezi kungayambitse mavuto aakulu.

• Ngati chifukwa chake ndi chotupa: Pangafunike opaleshoni kuti chotupacho chichotsedwe. Nthawi zina, chithandizo cha radiation chingaperekedwe kuwonjezera pa opaleshoni.
• Mankhwala ena: Ngati opaleshoni kapena chithandizo cha radiation sichikuyenda bwino, mankhwala angaperekedwe kuti achepetse kupanga kwa cortisol. Komabe, mankhwalawa amathanso kukhala ndi zotsatirapo zoyipa, choncho ayenera kumwedwa moyang'aniridwa ndi dokotala.

Kodi mungasinthe bwanji moyo ndi zakudya pamodzi ndi chithandizo?

Pamene mukulandira chithandizo, kusintha moyo wanu ndi zakudya zanu kungakuthandizeni kwambiri kuthana ndi zizindikiro zanu.

• Idyani zakudya zabwino:
• Idyani zakudya zokhala ndi calcium ndi vitamini D wambiri. Matendawa amafooketsa mafupa. Mkaka, yogurt, tchizi, ndiwo zamasamba zobiriwira, ndi nsomba zazing'ono (zokhala ndi mafupa) ndi zabwino.
• Chepetsani kudya zakudya zokhala ndi sodium wambiri ndi mafuta/mafuta ambiri . Izi zingayambitse kuthamanga kwa magazi komanso kunenepa kwambiri.
• Lamulirani ululu:Zinthu monga kusamba ndi madzi otentha, kupukutidwa pang'ono, komanso kuchita masewera olimbitsa thupi a m'madzi zingathandize kuchepetsa ululu wa minofu.
• Thanzi la maganizo: Vutoli likhoza kufooketsa. Lankhulani ndi achibale anu ndi anzanu za izi. Pemphani thandizo lawo. Ngati kuli kofunikira, funani thandizo kwa mlangizi. Mutha kufunsa dokotala wanu kuti akutsogolereni.

Matenda a Cushing, cortisol, ma steroids, mahomoni, kuthamanga kwa magazi, matenda a shuga, kufooka kwa thupi, nkhope ya mwezi, buffalo hump, pituitary gland, adrenal gland, zizindikiro za matenda a Cushing, chithandizo cha matenda a Cushing