Kodi kugunda kwa mtima wanu sikusinthasintha? Tiyeni tiphunzire za Dofetilide!

Kodi dokotala wakuuzani kuti pali vuto ndi kugunda kwa mtima wanu, kutanthauza liwiro la kugunda kwa mtima wanu? Muyenera kuti munachita mantha pang'ono, sichoncho? Dofetilide ndi mtundu wa mankhwala omwe amaperekedwa nthawi ngati zimenezi. Chifukwa chake, lero tikambirana za mankhwala awa otchedwa Dofetilide, ngati kuti tikuuza mnzanu.

Kodi Dofetilide ndi chiyani?

Mwachidule, Dofetilide ndi mankhwala oletsa kupweteka kwa mtima . Izi zikutanthauza kuti amathandiza kuti mtima wanu uyambe kugwira ntchito bwino. Nthawi zambiri imabwera ngati kapisozi. Nthawi zambiri imatengedwa kamodzi kapena kawiri patsiku. Mwina munaiwonapo pansi pa dzina la Tikosyn®.

Koma pali chinthu chimodzi choyenera kukumbukira. Mlingo wa mankhwalawa, ndiko kuti, kuchuluka kwa zomwe mwapatsidwa kuti mumwe, ukhoza kusiyana malinga ndi munthu . Ngati mnzanu akumwa mankhwalawa, simudzapatsidwa kuchuluka komweko monga momwe wapatsidwira. Dokotala adzayesa matenda anu ndikukupatsani mlingo woyenera (monga `125 mcg, 250 mcg` kapena `500 mcg`). `(mcg)` imayimira ma microgram.

Kodi Dofetilide imagwiritsidwa ntchito pazochitika ziti?

Mankhwalawa amagwiritsidwa ntchito makamaka pochiza mavuto ena a mtima komanso kupewa kuti asabwerenso.

Matenda a mtima

• Kugunda kwa mtima (Afib): Apa ndi pamene zipinda zapamwamba za mtima wanu (zomwe zimatchedwanso atria) zimagunda mofulumira komanso mosasinthasintha, osati mozungulira. Ganizirani ngati ng'oma yomwe imayenera kuimbidwa mwanjira inayake, koma imagunda molakwika ndipo imapita misala. Izi zimatchedwa ``Afib''.
• Kugundana kwa mtima: Iyi ndi njira ina yosazolowereka ya kugunda kwa mtima yomwe imachitika m'zipinda zapamwamba za mtima. Imafanana pang'ono ndi ``Afib``, koma pali kusiyana pang'ono.

Chofunika: Mu matenda onsewa, ntchito ya mtima imakhala yosakhazikika, kotero magazi sangapopedwe bwino. Izi zingayambitse mavuto osiyanasiyana. Chifukwa chake, mankhwalawa amagwira ntchito pokonza kusakhazikikako ndikupangitsa mtima kugwiranso ntchito bwino.

Kugwiritsa ntchito "Off-label"

Nthawi zina madokotala amalemba Dofetilide pa matenda ena a mtima kupatulapo kugwiritsa ntchito koyamba. Izi zimatchedwa kugwiritsa ntchito "kunja kwa chizindikiro". Izi zikutanthauza kuti madokotala amadziwa kuti mankhwalawa angathandize pa matenda amenewo, koma poyamba sanavomerezedwe pa matenda amenewo.

Matenda ena ofanana ndi a mtima ndi awa:

• Tachycardia ya Ventricular: Mu izi, zipinda zapansi za mtima zimagunda mofulumira kwambiri.
• Supraventricular Tachycardias: Iyi ndi kugunda kwa mtima mofulumira komwe kumachitika m'zipinda zapamwamba za mtima. Palinso mitundu ina kupatula `(Afib)` ndi `(Atrial Flutter).`
• Matenda a Wolff-Parkinson-White: Uwu ndi mkhalidwe womwe mtima umagunda mofulumira chifukwa cha njira yowonjezera yamagetsi mumtima.

Kodi mungayambe bwanji kugwiritsa ntchito Dofetilide?

Izi ndi zapadera pang'ono. Mukayamba kumwa Dofetilide, muyenera kukhala m'chipatala kwa masiku atatu kapena anayi . Izi zingamveke zachilendo pang'ono, eti? Chifukwa chake ndi chakuti madokotala akufuna kuyang'anira momwe mankhwalawa amakhudzira kugunda kwa mtima wanu komanso ngati mukukumana ndi mavuto atsopano. Adzagwiritsanso ntchito nthawiyi kupeza mlingo woyenera kwa inu. Mukakhala m'chipatala, angasinthe kuchuluka kwa mankhwala omwe mwapatsidwa. Musadandaule, zonsezi ndi za chitetezo chanu.

Kodi mungatenge bwanji Dofetilide kunyumba?

Mukafika kunyumba kuchokera kuchipatala, chizindikiro cha mankhwala chomwe mwapatsidwa chidzafotokoza momveka bwino kuchuluka kwa mankhwala omwe muyenera kumwa komanso kangati patsiku.

Ndikofunikira kwambiri kukumbukira mfundo izi:

• Imwani mankhwalawo monga momwe dokotala wanenera. Musawonjezere kapena kuchepetsa mlingo.
• Imwani mankhwala nthawi yomweyo tsiku lililonse. Ngati kuli m'mawa, imwani m'mawa, ngati kuli usiku, imwani usiku. Musasinthe nthawi.
• Ngakhale mutamva bwino, musasiye kumwa mankhwalawo. Pitirizani kumwa mankhwalawa bola ngati dokotala wanu wakuuzani.
• Mutha kumwa mankhwalawa muli ndi chakudya kapena ayi.
• Musamaleke kumwa mankhwala anu.
• Imwani kuchuluka kokha komwe dokotala wakupatsani.

Ngati muli ndi mafunso okhudza mankhwala anu kapena momwe mungawonjezerere mankhwala, musaope kufunsa dokotala wanu kapena wamankhwala. Ngati pali china chake chomwe simukumvetsa, afunseni kuti akufotokozereni.

Kodi ndiyenera kumuuza chiyani dokotala wanga ndisanayambe kumwa Dofetilide?

Musanakupatseni mankhwala awa, ndikofunikira kuuza dokotala wanu izi:

• Kodi munayamba mwakhalapo ndi vuto la dofetilide? Ngati ndi choncho, chonde fotokozani zomwe zinachitika.
• Lembani mankhwala onse omwe mukumwa (mankhwala ochokera kwa dokotala, omwe amagulitsidwa ndi dokotala nthawi zonse, mavitamini, ndi mankhwala ena owonjezera). Musayambe mankhwala atsopano kapena mankhwala owonjezera popanda kufunsa dokotala wanu kaye.
• Tiuzeni ngati muli ndi matenda a mtima, makamaka matenda a mtima otchedwa `Long QT Syndrome` , kapena ngati muli ndi matenda a impso kapena chiwindi, kapena ngati muli ndi potaziyamu kapena magnesium yochepa m'magazi mwanu.
• Onetsetsani kuti mwatiuza ngati muli ndi pakati, mukufuna kutenga pakati, kapena ngati mukuyamwitsa .

Ndi mankhwala ati omwe sayenera kumwedwa ndi Dofetilide?

Ngati mukumwa mankhwala awa, kumwa Dofetilide kungakhale koopsa kwambiri.Choncho, ngati mukugwiritsa ntchito mankhwala ngati awa, muyenera kuuza dokotala wanu. Mukatero sadzakupatsani Dofetilide.

• Cimetidine (monga Tagamet®)
• Cisapride
• Dolutegravir (`Dolutegravir` - mwachitsanzo `Tivicay®`)
• Verapamil (`Verapamil` - mwachitsanzo `Calan®`)
• Ketoconazole
• Itraconazole (monga Sporanox®)
• Trimethoprim (`Trimethoprim` - mwachitsanzo `Proloprim®`)
• Trimethoprim yokhala ndi sulfamethoxazole (monga Bactrim®, Septra®)
• Hydrochlorothiazide (`Hydrochlorothiazide` - mwachitsanzo `Microzide®`)
• Ziprasidone
• Mankhwala oletsa kuvutika maganizo a tricyclic monga amitriptyline
• Promethazine
• Prochlorperazine (monga Compro®)
• Quinidine
• Disopyramide (monga Norpace®)
• Sotalol (`Sotalol` - mwachitsanzo `Betapace®`)

Mankhwala ena omwe angagwirizane ndi Dofetilide

Pali mankhwala ena omwe angagwirizane ndi Dofetilide. Izi zikutanthauza kuti ngati mumwa mankhwalawa pamodzi, angasinthe momwe Dofetilide imagwirira ntchito kapena kuwonjezera zotsatira zake zoyipa. Chifukwa chake, ngati mukumwa mankhwala aliwonse omwe ali pansipa, lankhulani ndi dokotala wanu musanayambe kumwa Dofetilide.

• Amiodarone (`Amiodarone` - e.g. `Cordarone®`)
• Digoxin (`Digoxin` - mwachitsanzo `Lanoxin®`)
• Metformin (`Metformin` - mwachitsanzo `Glucophage®`)
• Megestrol
• Diltiazem (monga Cardizem®)
• Zafirlukast
• Quinine
• Fluconazole
• Erythromycin (`Erythromycin` - mwachitsanzo `PCE®`)
• Clarithromycin
• Mankhwala opha tizilombo a Fluoroquinolone monga Norfloxacin ndi Moxifloxacin
• Ma SSRI (Selective Serotonin Reuptake Inhibitors) monga Fluoxetine, Sertraline, Paroxetine (monga Paxil®)
• Mankhwala ochotsa madzi m'thupi monga Furosemide, Triamterene, ndi Amiloride
• Mankhwala oletsa ma protein (mankhwala a matenda monga HIV) monga Indinavir

Kungodziwa: Monga mankhwala ena, kumwa madzi a mphesa (chipatso chofanana ndi mphesa) kungapangitse kuti dofetilide ichuluke m'thupi mwanu. Izi zitha kukhala zoopsa. Chifukwa chake, funsani dokotala wanu ngati kuli bwino kumwa madzi a mphesa mukumwa mankhwalawa.

Kodi mungachite chiyani ngati mwaphonya mlingo wa mankhwala?

Ngati izi zitachitika, imwani mlingo womwe mwaphonya nthawi yomweyo mukakumbukira . Komabe, ngati nthawi yatsala pang'ono yoti mutenge mlingo wotsatira ikafika, thawani mlingo womwe mwaphonya ndikumwa mlingo wotsatira panthawi yomwe mwakonza. Musamwe mlingo wowirikiza kawiri. Ngati simukudziwa choti muchite, lankhulani ndi dokotala wanu kapena wamankhwala.

Kodi ubwino wa Dofetilide ndi wotani?

Dofetilide ingathandize kulamulira kugunda kwa mtima kosakhazikika mumtima mwanu, zomwe zingapangitse moyo wanu kukhala wosavuta. Komabe, ndikofunikira kukumbukira kuti sichitha matenda onse.

Kodi zotsatirapo zoyipa za Dofetilide ndi ziti?

Monga mankhwala ena aliwonse, Dofetilide ingayambitse zotsatira zina zoyipa. Si aliyense amene amalandira, koma ndibwino kudziwa za izo.

Zotsatirapo zazing'ono zomwe zingatheke:

• Kupweteka pachifuwa
• Mutu (kupweteka mutu)
• Chizungulire (vertigo)
• Kumva ngati kusanza (kumva ngati kusanza)
• Kutsegula m'mimba (kupweteka m'mimba)
• Kupweteka m'mimba

Chinthu choyenera kusamala nacho kwambiri:

Dofetilide imaperekedwa kuti ikonze kugunda kwa mtima kosakhazikika, koma pali chiopsezo cha mtundu wina wa kugunda kwa mtima kosakhazikika ndi mankhwalawa. Makamaka, kugunda kwa mtima mofulumira m'zipinda zapansi pa mtima (`ventricular tachycardia`) yotchedwa ``Torsades de Pointes`` kungachitike.

Ichi ndi chifukwa chachikulu chomwe muyenera kugonekedwa m'chipatala ndikuyamba kumwa mankhwala! Madokotala akufuna kukuyang'anirani mosamala kuti mudziwe ngati pali kugunda kwa mtima koopsa komanso kosazolowereka kumeneku.

Kodi ndidzakhala bwino nthawi yayitali bwanji nditayamba kumwa mankhwala?

Dofetilide imatenga maola awiri kapena atatu kuti iyambe kugwira ntchito. Komabe, ngakhale mutamva bwino, musasiye kumwa mankhwalawo mpaka dokotala wanu atakuuzani kuti mutero. Pitirizani kumwa.

Kodi ndingasamalire bwanji thanzi langa ndikumwa Dofetilide?

Pali zinthu zingapo zomwe muyenera kuchita mukamamwa mankhwalawa.

• Onetsetsani kuti mwapita kukaonana ndi dokotala wanu nthawi zonse, kuphatikizapo mayeso a labu. Pamenepo ndi pomwe mutha kuwona momwe mankhwalawo akukukhudzirani.
• Mwina mungafunike kuyesedwa ndi electrocardiogram (EKG) kamodzi pa miyezi isanu ndi umodzi iliyonse . Izi zidzakuthandizani kuona momwe mtima wanu umagunda komanso momwe umagwirira ntchito.
• Angapemphenso kuti ayesedwe magazi kuti awone ngati mlingo wa mankhwalawo ukufunika kusinthidwa.
• Nthawi zonse werengani kabuku ka malangizo komwe kamabwera ndi mankhwala anu, makamaka ngati pakhala kusintha kulikonse kwaposachedwa kwa mankhwala anu kapena thanzi lanu. Funsani wamankhwala wanu ngati muli ndi mafunso.

Zinthu zina zomwe mungachite:

• Ngati mukuchitidwa opaleshoni, opaleshoni ya mano, kapena chithandizo chadzidzidzi, uzani dokotala kapena dokotala wa mano kuti mukumwa Dofetilide.
• Mungafunikenso kuvala khadi losonyeza kuti mukumwa Dofetilide.
• Musasiye kumwa mankhwalawa popanda kufunsa dokotala wanu.
• Tsatirani malangizo a dokotala wanu okhudza chakudya ndi zakumwa, makamaka zakumwa zoledzeretsa.
• Nthawi zonse khalani ndi mankhwala okwanira . Musanapite kutchuthi kapena paulendo, yang'anani ngati mankhwala anu akuchepa. Kupanda kutero, simungawapeze pakagwa ngozi.

Kodi muyenera kupita kwa dokotala liti?

Ngati mukukumana ndi zizindikiro izi, imbani dokotala nthawi yomweyo kapena pitani kuchipatala chadzidzidzi:

• Kugunda kwa mtima mofulumira kapena kosasinthasintha.
• Kumva ngati mtima wako ukugunda mofulumira, kumva ngati kugunda kwa mtima wako kukuthamanga.
• Kupweteka pachifuwa.
• Chizungulire kapena kumva mutu wopepuka (`mutu wopepuka`).
• Kuvuta kupuma.
• Kutsegula m'mimba kwambiri.
• Kusanza ndi kusowa chilakolako cha chakudya.
• Kutuluka thukuta kosazolowereka.
• Kuwonjezeka kwa ludzu la madzi.
• Kutupa pakhungu.

Ngakhale ngati pali zotsatirapo zoyipa ngati izi, lankhulani ndi dokotala wanu ngati zikukuvutitsani:

• Mutu.
• Kusowa tulo.
• Zotsatira zina zilizonse zomwe zimakuvutitsani.

Kodi ndingagule kuti Dofetilide?

Dofetilide siipezeka m'ma pharmacy onse. Chifukwa chake, imbani pharmacy yapafupi kuti mudziwe ngati ali nayo. Ngati mukuvutika kupeza mankhwalawo, lankhulani ndi dokotala wanu.

Kodi mungasunge bwanji Dofetilide?

• Sungani Dofetilide mu chidebe chotsekedwa bwino, kutentha kwa chipinda, pamalo ouma .
• Musaike pamalo omwe dzuwa lawamba kapena pamalo otentha.
• Musasunge mankhwalawa m'malo omwe ali ndi chinyezi chambiri, monga m'bafa. Chinyezi chingawononge mphamvu za mankhwalawa.
• Musasunge mankhwala awa okha, komanso mankhwala ena onse kutali ndi ana.
• Musagawire mankhwala anu ndi wina aliyense.
• Musagwiritse ntchito mankhwala omwe atha ntchito. Mapaketi ena a mankhwala ali ndi tsiku lotha ntchito. Kapena, ngati simukudziwa kuti mankhwalawo ndi akale bwanji, imbani sitolo yanu ya mankhwala ndikufunsani.

Pomaliza, zinthu zoti muzikumbukira

Zingakhale zovutitsa kwambiri kudziwa kuti muli ndi vuto la mtima. Komabe, ngati dokotala wanu wakupatsani mankhwala a Dofetilide, angakuthandizeni. Chofunika kwambiri ndikutsatira malangizo a dokotalayo komanso malangizo omwe ali pa phukusi la mankhwalawo. Ngati muli ndi mafunso ena kapena nkhawa zokhudzana ndi mankhwalawa, musazengereze kufunsa dokotala wanu kapena wamankhwala. Adzakuthandizani.

Dofetilide , Kugunda kwa mtima, Arrhythmia, Atrial fibrillation, Atrial flutter, Tikosyn, Matenda a mtima