Timaganiza kuti sitingasinthe zinthu zomwe timalandira kuchokera kwa makolo athu, sichoncho? Sikuti ndi mtundu wa maso okha, kapangidwe ka tsitsi, mtundu wa khungu, kutalika, komanso chiopsezo chotenga matenda enaake... Tikudziwa kuti zonsezi zimachokera ku majini athu. Chifukwa chake timaganiza kuti majini awa ali ngati chinthu chosemedwa mumwala, chosasinthika, komanso chomwe sitingathe kuchilamulira. Koma... kodi mungadabwe ngati titauzidwa kuti tingasinthe "momwe" majini awa "amagwirira ntchito" kudzera m'moyo wathu, chakudya chomwe timadya, ndi zinthu zomwe timachita? Epigenetics ndi gawo la sayansi latsopano komanso lodabwitsa kwambiri lomwe limalankhula za izi.
Mwachidule, kodi Epigenetics ndi chiyani?
Izi zingamveke ngati mawu asayansi, koma lingaliro lake ndi losavuta. Tiyeni tifotokoze mwachidule mawu akuti 'Epigenetics'. 'Epi' ndi Chigiriki chotanthauza "pamwamba, mozungulira, kunja." 'Genetics' ndi sayansi ya majini. Ndipo 'Epigenetics' ikunena za ulamuliro womwe ulipo "pamwamba pa majini."
Taganizirani izi motere. Majini anu ali ngati mababu a magetsi m'nyumba mwanu. Simungasinthe mababu amenewo kapena komwe ali. Ndi chinthu chomwe mumatengera. Koma muli ndi switch yomwe imasankha ngati babuyo ikuyaka kapena kuzimitsa. Mwina babuyo ili ndi switch yozimitsa yomwe imayatsa ndi kuzimitsa.
Mofananamo, `Epigenetics` ndi nkhani yokhudza dongosolo la "kusintha kwa mankhwala" komwe kumayang'anira ngati majini m'thupi lathu ayamba kugwira ntchito (kuyatsidwa/kutsekedwa), kapena ngati ntchito yawo yachepa (kuchepetsedwa), popanda kusintha babu lotchedwa majini.
Kusintha kwa mankhwala kumeneku kumakhudzidwa ndi zinthu zambiri, kuphatikizapo moyo wathu, chakudya chomwe timadya, malo omwe timakhala, komanso nkhawa zomwe timakumana nazo. Nthawi zina kusintha kumeneku kumakhala kwabwino pathupi lathu, kutiteteza ku matenda. Nthawi zina, kumatha kuwononga thanzi lathu.
Tiyeni tidzikumbutse pang'ono za majini ndi DNA zomwe zili?
Kuti timvetse izi, choyamba tiyeni tione mwachidule majini ndi DNA.
Ganizirani za mndandanda wanu wonse wa `DNA` ngati buku lalikulu la maphikidwe . Buku lalikulu ili lili ndi malangizo onse omwe selo lililonse m'thupi lanu limafunika kuti ligwire ntchito yake bwino. Maselo amaphunzira zomwe angachite komanso momwe angachitire mwa ``kuwerenga`` buku la ``DNA`` ili.
M'thupi mwathu muli maselo ambirimbiri. Maselo a khungu, maselo a mtima, maselo a ubongo, ndi zina zotero. Selo lililonse lili ndi buku lonse la maphikidwe a "DNA".
Koma, si selo lililonse lomwe limawerenga buku lonseli. Siliyenera kutero. Tangoganizani, selo la khungu silifunikira malangizo ochokera ku selo la mtima a momwe lingagwirire ntchito. Monga momwe keke silifunikira njira yophikira sambol.
Ma gene ndi maphikidwe omwe ali m'buku lalikulu la maphikidwe.Chifukwa. Jini ili ngati mutu m'buku lomwe limakulangizani kuti muchite ntchito inayake. Chifukwa chake, khungu limangowerenga malangizo (majini) a khungu. Selo la mtima limangowerenga malangizo a mtima.
Zimene `Epigenetics` imachita ndi kusankha njira yophikira yomwe selo lililonse liyenera kuwerenga ndi yomwe siliyenera kuwerenga. Zili ngati kuyika chizindikiro pamasamba ena a buku la maphikidwe chomwe chimati "Gwiritsani ntchito izi tsopano" ndi masamba ena omwe amati "Musayang'ane izi tsopano."
Kodi n’chiyani chimakhudza Epigenome yathu?
'Epigenome' ndi dongosolo lomwe limapangidwa ndi majini athu ndi 'kusintha kwa mankhwala' komwe kumalamulira momwe majini amenewo amagwirira ntchito. Chofunika ndichakuti 'epigenome' iyi siimangokhala yokhazikika. Imasintha pakapita nthawi, ndi zinthu zomwe zimachitika m'miyoyo yathu.
Zinthu zomwe zimakhudza kusinthaku zimayamba tisanabadwe. Onani zomwe zili mu tebulo ili m'munsimu.
| Chinthu chomwe chimakhudza | Kufotokozera kosavuta ndi zitsanzo |
|---|---|
| Matenda a mayi panthawi ya mimba | Zinthu monga zakudya za mayi, thanzi lake la maganizo, ndi nkhawa zomwe amakumana nazo zingakhudze momwe majini a mwana ali m'mimba amagwirira ntchito. |
| Zakudya ndi zokumana nazo zaubwana | Zakudya, chikondi cha makolo, chitetezo, ndi mwayi wophunzira ali mwana komanso ali mwana zimapangitsa kuti mwana akhale ndi zizindikiro za epigenetic zomwe zimakhudza thanzi la mwana mtsogolo. |
| Zakudya | Zakudya zomwe timadya tikakula, makamaka zakudya zokonzedwa kale, zakumwa zotsekemera, ndi zakudya zamafuta, zimakhala ndi zotsatirapo zoyipa, pomwe zakudya zopatsa thanzi monga ndiwo zamasamba, zipatso, ndi nyemba zimakhala ndi zotsatirapo zabwino. |
| Kuchita masewera olimbitsa thupi | Kuchita masewera olimbitsa thupi kungayambitse majini olimbikitsa thanzi ndikuletsa majini osagwira ntchito bwino. |
| Poizoni ndi mankhwala ophera tizilombo m'chilengedwe | Kukhudzidwa ndi utsi wa galimoto, utsi wa ndudu, mankhwala monga (BPA) mu mapulasitiki, mankhwala a agrochemicals, ndi zitsulo zolemera monga lead kungapangitse majini kukhala ndi zizindikiro zoopsa. |
| Kupsinjika maganizo | Kupsinjika maganizo kwa nthawi yayitali kungasokoneze ntchito ya majini m'thupi lathu ndipo kungayambitse matenda angapo. |
| Mowa ndi mankhwala osokoneza bongo | Kugwiritsa ntchito mowa, fodya, ndi mankhwala ena osokoneza bongo kumawononga mwachindunji epigenome yathu. |
Ndi matenda ati omwe angagwirizane ndi epigenetics?
Asayansi akufufuzabe izi, koma chomwe chikudziwika pakadali pano ndichakuti kusintha kwa epigenetic kumalumikizidwa ndi matenda angapo.
- Khansa: Tangoganizirani, tili ndi jini m'thupi mwathu yomwe imaletsa maselo a khansa kukula. Koma chimachitika ndi chiyani ngati jini iyi 'yatsekedwa', kutanthauza kuti, yatsekedwa, chifukwa cha moyo woipa? Maselo a khansa amapatsidwa mwayi wokukula popanda kulamuliridwa.
- Matenda a muubongo: Pali umboni wakuti kusintha kwa majini kumakhudzana ndi matenda okhudzana ndi ukalamba monga matenda a Parkinson ndi matenda a Alzheimer, komanso matenda ena amisala ndi zilema zamaganizo.
- Kagayidwe kachakudya: Matenda monga matenda a shuga ndi kunenepa kwambiri amakhudzidwa ndi momwe majini athu amagwirira ntchito. Zakudya zathu zimatha kusintha momwe majini awa amagwirira ntchito.
- Ukalamba: Zizindikiro za 'epigenetic' izi zimakhudzanso ukalamba ndi matenda ena okhudzana nawo.
- Matenda a chitetezo chamthupi: Izi zimagwirizananso ndi matenda a 'autoimmune' monga mphumu ndi nyamakazi, zomwe zikutanthauza matenda omwe chitetezo chamthupi chimaukira maselo ake.
Pamene kafukufuku pa izi akupitirira, asayansi akuyembekeza kupeza mankhwala atsopano ndi njira zochiritsira pogwiritsa ntchito 'epigenome' iyi.
Ndiye kodi tingasinthe epigenome yathu kuti ikhale yabwino?
Inde, zingathekedi!Uthenga wabwino ndi wakuti. Ngakhale sitingasinthe majini omwe timalandira, tingasinthe momwe majiniwo amagwirira ntchito. Ngakhale kuti palibe njira imodzi yokha yodziwikiratu yochitira izi, asayansi amakhulupirira kuti tingasinthe 'epigenetic' mwa kuchita izi:
Zinthu zomwe mungadzichitire nokha
- Idyani zakudya zopatsa thanzi: Phatikizani zakudya zambiri zophikidwa kunyumba monga ndiwo zamasamba, zipatso, masamba obiriwira, tirigu wonse, ndi nsomba. Chepetsani zakudya zopakidwa m'matumba, zokonzedwa, komanso zokhala ndi shuga wambiri komanso mafuta ambiri.
- Phatikizani masewera olimbitsa thupi mu zochita zanu za tsiku ndi tsiku: Chitani zinthu monga kuyenda, kuthamanga, kapena kukwera njinga kwa mphindi zosachepera 30 patsiku. Komabe, ngati ndinu watsopano kuchita masewera olimbitsa thupi, ndikofunikira kulankhula ndi dokotala wanu kaye kuti mudziwe mtundu wa masewera olimbitsa thupi omwe ndi oyenera kwa inu.
- Chepetsani kumwa mowa ndipo pewani kusuta fodya kotheratu: Izi ndi zinthu zomwe zimawononga mwachindunji 'DNA' ndi 'epigenome' yathu.
- Pewani kupsinjika maganizo: Mutha kuchepetsa kupsinjika maganizo mwa kuchita zinthu monga kusinkhasinkha, yoga, kumvetsera nyimbo zabwino, kuchita zinthu zomwe mumakonda, komanso kukambirana ndi mnzanu wodalirika.
Ngati ndinu kholo, nazi zina zomwe mungachite kwa mwana wanu:
'Epigenome' yathu imasinthasintha kwambiri m'zaka zoyambirira za moyo, kotero ndikofunikira kuti makolo adziwe izi.
- Perekani zakudya zoyenera kwa mwana wanu: Funsani dokotala wa ana za izi.
- Perekani mwana wanu mwayi wophunzira ndi kusewera: Lankhulani ndi mwana wanu, werengani mabuku, phunzitsani mawu atsopano, ndipo mupatseni zoseweretsa zokulitsa ubongo.
- Pangani malo achikondi komanso otetezeka: Pangani malo kunyumba komwe mwana amamva kuti ali otetezeka, amakondedwa, komanso akusamalidwa.
- Ngati mukukumana ndi mavuto monga kusowa chakudya, mavuto a nyumba, kapena nkhanza zapakhomo, chonde funsani thandizo kwa dokotala kapena mkulu woyenera . Adzakutsogolerani kuti mupeze chithandizo chomwe inu ndi ana anu mukufunikira.
Tikamva lingaliro la 'Epigenetics', timamva kudabwa, chiyembekezo, ndi mantha pang'ono kumbali imodzi. Tikaganizira zomwe zimachitika m'thupi lathu, nthawi zina timamva ngati zinthuzo sitingathe kuzilamulira. Koma 'Epigenetics' imatiphunzitsa kuti ngakhale pali zinthu zomwe sitingathe kuzilamulira, tili ndi mphamvu zopanga zisankho zokhudzana ndi thanzi lathu ndikupanga kusintha kwabwino.
Uthenga Wopita Nawo Kunyumba
- Ngakhale simungasinthe majini omwe mumalandira kuchokera kwa makolo anu, mutha kusintha momwe majini amenewo amayatsira/kuzimitsira.
- Zinthu monga zakudya zanu, masewera olimbitsa thupi, kupsinjika maganizo, ndi malo omwe mumakhala zimakhudza mwachindunji momwe majini anu amagwirira ntchito. Izi zimatchedwa epigenetics.
- Zina mwa zosinthazi zingakhale zothandiza pa thanzi lanu, pomwe zina zingayambitse matenda monga khansa ndi matenda a shuga.
- Kudya zakudya zopatsa thanzi, kuchita masewera olimbitsa thupi, kupewa kusuta fodya ndi kumwa mowa, komanso kuthana ndi nkhawa kungathandize kwambiri majini anu.
- Zakudya ndi chisamaliro chomwe ana amalandira, makamaka akangoyamba kumene moyo wawo, zimakhudza thanzi lawo lamtsogolo kwa nthawi yayitali.
- Ngati muli ndi mafunso ena okhudza izi, lankhulani ndi dokotala wa banja lanu.
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