Kodi matenda a Evans Syndrome ndi chiyani? Tiyeni tikambirane za izi!

Kodi nthawi zina mumamva kutopa? Kapena mumavutika kusiya kutuluka magazi ngakhale pazinthu zazing'ono? Mwina ndi chifukwa chakuti chitetezo cha mthupi lanu chikukugwirani ntchito. Lero tikambirana za vuto losowa koma lofunika kwambiri loti mudziwe. Limenelo ndi Evans Syndrome . Musadandaule, tikambirana chilichonse mwachidule.

Ndiye kodi Evans Syndrome ndi chiyani?

Mwachidule, matenda a Evans Syndrome ndi matenda omwe amayambitsa chitetezo chamthupi . Chomwe chimachitika ndichakuti asilikali omwe akuyenera kuteteza thupi lathu, chitetezo chamthupi, amayamba kuwononga maselo athu ena amagazi molakwika. Zili ngati gulu lathu lankhondo likuukira anthu athu. Zotsatira zake, thupi lathu limataya maselo ofunikira amagazi. Kuchepa kwachilendo kwa maselo amagazi ndi komwe timatcha cytopenia mu zamankhwala.

Anthu ambiri omwe ali ndi matenda a Evans Syndrome amayamba kukhudzidwa ndi kuchepa kwa maselo ofiira m'magazi (vuto lotchedwa anemia ) ndi ma platelet (vuto lotchedwa thrombocytopenia ). Kuwonjezera pa zonsezi, anthu ena angakhalenso ndi kuchuluka kochepa kwa maselo oyera amagazi otchedwa neutrophils (vuto lotchedwa neutropenia ).

Pamene maselo a magazi awa ali ochepa, zinthu zambiri zofunika m'thupi lathu, monga kupeza mpweya, kuundana kwa magazi, ndi kulimbana ndi matenda, zimakhudzidwa. Ndicho chifukwa chake timamva kufooka, kutopa, kuyamba kutuluka magazi mosavuta, komanso kudwala pafupipafupi .

Matendawa angakhudze anthu ena pang'ono kwambiri, pomwe ena akhoza kukhala oopsa kwambiri. Ndipo zotsatira zake sizimakhala chimodzimodzi kwa moyo wawo wonse. Chabwino n'chakuti ngakhale palibe mankhwala, chithandizo chingathandize kuchepetsa zizindikiro ndikuchepetsa zotsatira zake .

Kodi zizindikiro za matenda a Evans Syndrome ndi ziti?

Zizindikiro za Evans Syndrome zimatha kusiyana kwambiri. Zimatengera mtundu wa cytopenia womwe muli nawo komanso momwe ulili woopsa. Nthawi zambiri, kuchepa kwa magazi m'thupi kapena thrombocytopenia kumachitika koyamba, ndipo zina zimaonekera pambuyo pake.

Zizindikiro zoyambirira za kusowa kwa maselo ofiira a magazi ( anemia ):

Kodi mwatopa ngakhale mutayenda mtunda waufupi? Kodi mukumva kutopa ndipo simungathe kuchita zinthu zomwe munkachita kale? Mwina nkhope yanu ikuwoneka yotuwa pang'ono. Izi ndi zina mwa zizindikiro zoyambirira za kuchepa kwa magazi m'thupi :

• Kungomva kutopa kwambiri.
• Khungu lotumbululuka (lotuwa) .
• Kusamva bwino kapena chizungulire .
• Kuvuta kupuma (kupuma movutikira) .
• Kugunda kwa mtima mwachangu (tachycardia) .
• Kumva kapena kumva ngati mtima wanu ukugunda modabwitsa (kugunda kwa mtima) .

Zizindikiro zoyambirira za kusowa kwa ma platelet m'magazi (thrombocytopenia):

Kodi mwaona kuti nthawi zina madontho ofiira ang'onoang'ono amaonekera pakhungu lanu? Kapena mumangomva mabala thupi lonse? Kodi mumamva ngati m'kamwa mwanu mukutuluka magazi kwambiri kuposa nthawi zonse mukamatsuka mano anu? Izi ndi zizindikiro zomwe zingayambitse kuchepa kwa magazi m'thupi:

• Madontho ang'onoang'ono ofiira otuluka magazi (petechiae) pansi pa khungu.
• Madontho ofiirira pakhungu (purpura) .
• Kutupa (ecchymosis) komwe kumachitika popanda chifukwa.
• Kutuluka magazi ambiri m'kamwa kapena m'mphuno.
• Kutuluka magazi ambiri panthawi ya msambo mwa akazi.
• Kutuluka magazi ndi ndowe kapena mkodzo.

Zizindikiro za neutropenia (izi zitha kuchitika kapena sizingachitike pambuyo pake):

Ndizachilendo kudwala chimfine kamodzi kapena kawiri pamwezi. Koma kodi nthawi zambiri mumadwala malungo? Kodi mumadwala zilonda pakamwa nthawi zonse? Kodi zimaoneka kuti zimatenga nthawi yayitali kuti zichiritsidwe? Nazi zina zomwe zingachitike ngati ma neutrophils anu ali ochepa:

• Malungo.
• Zilonda pakamwa.
• Chimfine, malungo, ndi kupweteka m'mimba pafupipafupi.
• Matenda a m'khutu omwe amabwerezabwereza.
• Matenda a bowa kwa nthawi yayitali.
• Matenda a mkodzo (UTIs) .

Zizindikiro zina za Evans Syndrome (izi zitha kuchitika nthawi zina):

• Ma lymph nodes otupa pakhosi.
• Nthata yokulirapo .
• Chiwindi chokulirapo .
• Matenda a chikasu .

N’chifukwa chiyani matenda a Evans amachitika?

Monga tanenera kale, Evans Syndrome ndi matenda omwe amayambitsa chitetezo chamthupi . Izi zikutanthauza kuti chitetezo chamthupi lathu chimazindikira molakwika maselo ena amagazi athu ngati "mdani" ndipo chimayamba kuwaukira.

Ntchito imeneyi imachitika ndi maselo a B, mtundu wapadera wa selo m'thupi lathu. Maselo a B amenewa amapanga chinthu chotchedwa ma antibodies . Ma antibodies amenewa amapita kukagwira maselo osalakwa a magazi ndikuwawononga. Kawirikawiri, amayamba kuukira mtundu umodzi wa selo la magazi poyamba, kenako amatha kuyamba kuukira mitundu ina ya maselo a magazi.

Njira imeneyi ndi imene imapangitsa kuti mukhale ndi vuto la mitundu iwiri ya maselo a m'magazi (cytopenia), ndipo nthawi zina mitundu yonse itatu. Kusowa kwa maselo onse atatu kumatchedwa pancytopenia . Zinthu zitatu zazikulu zomwe maselo a m'magazi awa amakhala ochepa ndi izi:

• Kuchepa kwa magazi m'thupi (Autoimmune hemolytic anemia) (AIHA)Apa ndi pamene maselo ofiira a magazi amachepa. Izi zikutanthauza kuti, amawonongeka mofulumira kuposa momwe thupi lingawapangire.
• Kutupa kwa chitetezo chamthupi (ITP) : Iyi ndi vuto lomwe kuchuluka kwa ma platelet m'magazi kumachepa. Chitetezo cha mthupi chimaukira ndikuchotsa ma platelet m'magazi.
• Matenda a Autoimmune neutropenia (AIN) : Uwu ndi mkhalidwe womwe kuchuluka kwa ma neutrophils, mtundu wa maselo oyera amagazi, kumachepa. Chitetezo cha mthupi chimaukira ndikuwononga ma neutrophils.

Taganizirani izi, pakhoza kukhala zifukwa zambiri zomwe zimapangitsa kuti maselo a m'magazi achepe (cytopenia). Nthawi zina zimakhala chifukwa chakuti mafuta a m'mafupa sapanga maselo okwanira a m'magazi. Komabe, mu cytopenia yodziyimira payokha, chitetezo chamthupi chimawononga maselo ake a m'magazi.

Kodi ndi zinthu ziti zomwe zimayambitsa matenda a Evans Syndrome?

Asayansi sakudziwabe chifukwa chake matenda odziteteza ku matenda amenewa amayamba. Koma aona kuti matenda amenewa nthawi zambiri amayamba munthu akadwala kwambiri kapena akakumana ndi vuto lomwe limaika chitetezo chamthupi pamavuto ambiri. Izi zimatchedwa zinthu zoyambitsa matenda .

Komanso, ngati muli ndi matenda amodzi odziteteza ku matenda enaake, muli ndi mwayi waukulu wopeza matenda ena. Zili ngati kuti matenda a chitetezo chamthupi awa amafalikira kuchokera mbali imodzi ya thupi kupita ku ina.

Matenda a Evans angachitike okha (amatchedwa matenda oyamba a Evans ), kapena angachitike ngati matenda ena (amatchedwa matenda achiwiri a Evans) . Zina mwa matenda omwe angagwirizane ndi izi ndi awa:

• Lupus erythematosus (lupus)
• Kusowa kwa chitetezo chamthupi chosiyanasiyana
• Kusowa kwa IgA yosankha
• Matenda a Sjögren
• Non-Hodgkin lymphoma
• Khansa ya m'magazi yosatha
• Matenda a chiwindi a C osatha
• Matenda a kachilombo ka HIV osatha

Ngati muli ndi matenda oyamba a Evans, mwina adayamba mutadwala kwakanthawi, kapena simungakhale ndi chifukwa chodziwikiratu. Asayansi amaika matenda a Evans ngati vuto losazolowereka . Izi zikutanthauza kuti palibe chifukwa chomwe chapezeka.

Kodi mavuto omwe angakhalepo chifukwa cha matenda a Evans Syndrome ndi ati?

Si aliyense amene ali ndi matenda a Evans Syndrome amene angakumane ndi mavuto. Anthu ena amakhala ndi zizindikiro zochepa chabe. Komabe, pakakhala zovuta kwambiri, kusowa kwa maselo a m'magazi (cytopenias) kungakhale koopsa. Mwachitsanzo:

• Ngati palibe maselo ofiira okwanira onyamula mpweya kupita ku thupi, ndiye kuti mpweya m'magazi sumakhala wokwanira (hypoxemia) . Izi zimavuta kwambiri pamtima ndipo zingayambitse matenda a mtima komanso kulephera kwa mtima.
• Ngati mulibe ma platelet okwanira , omwe amathandiza magazi kuundana, magazi anu satseka bwino. Izi zingapangitse kuti mutuluke magazi mosavuta komanso mwachangu. Izi zingayambitse kuchepa kwa magazi m'thupi mwachangu.
• Thupi lanu likataya ma neutrophils , omwe amathandiza kulimbana ndi matenda, mumakhala ndi mwayi wopeza matenda pafupipafupi, ndipo amatha kukhala oopsa ndikufalikira m'thupi lonse. Izi zingayambitse matenda oopsa otchedwa sepsis .

Kodi madokotala amazindikira bwanji matenda a Evans Syndrome?

Matenda a Evans Syndrome amapezeka kudzera mu kuyezetsa magazi . Angadziwike ngati mukupeza zizindikiro za cytopenia, kapena pamene mukuwerengera maselo a magazi nthawi zonse.

Ngati Kuchuluka kwa Magazi (CBC) kwanu kukuwonetsani kuti muli ndi maselo ofiira a magazi, ma platelet, kapena ma neutrophils ochepa, gulu lanu lachipatala lidzachita mayeso ambiri. Mwachitsanzo, adzayang'ana magazi anu kuti awone kuchuluka kwa ma antibodies okhudzana ndi Evans Syndrome. Adzayang'ananso matenda ena omwe angayambitse cytopenia, monga matenda enaake kapena khansa.

Madokotala amatsimikiza za matenda a Evans Syndrome pochotsa zifukwa zina zonse. Nthawi zina, angafunikenso kuchita CT scan (computed tomography scan) kapena bone marrow biopsy kuti apeze matenda ena.

Kodi pali mankhwala athunthu a matenda a Evans Syndrome? Kodi amachiritsidwa bwanji?

Ndipotu, palibe mankhwala athunthu a Evans Syndrome, kapena matenda ena aliwonse odziteteza ku matenda a autoimmune. Madokotala amachiritsa matenda odziteteza ku matenda awa pokupatsani mankhwala omwe amachepetsa mphamvu ya chitetezo chamthupi chanu.

Kuphatikiza apo, zizindikiro zanu zitha kuchiritsidwa padera. Mwachitsanzo, ngati kuchuluka kwa maselo m'magazi anu kuli kochepa kwambiri, dokotala wanu atha kukonza izi mwa kuyika magazi nthawi zina.

Monga matenda ambiri a autoimmune omwe amatenga nthawi yayitali, Evans Syndrome imatha kukulirakulira pakapita nthawi. Nthawi zina zizindikiro zimatha kuoneka ngati zikutha (zotchedwa relieve) , koma kenako zimatha kubwereranso kapena kukulirakulira (zotchedwa relaxation ).

Mungafunike kuyesa njira zosiyanasiyana zochiritsira pa moyo wanu wonse, chifukwa kupambana kwawo kumatha kusiyana pakapita nthawi. Dokotala wanu adzayesa kukutetezani ku mavuto aakulu a Evans Syndrome.

Kodi mankhwala ake ndi otani?

Chithandizo chodziwika bwino cha Evans Syndrome ndi mankhwala oletsa chitetezo chamthupi , ndipo ngati pakufunika, kuikidwa magazi. Mankhwala oletsa chitetezo chamthupi amenewa amagwira ntchito pochepetsa kuukira kolakwika kwa chitetezo chamthupi chanu.

Mitundu ikuluikulu ya mankhwala operekedwa:

• Mankhwala a Corticosteroids , monga prednisone . Nthawi zambiri awa ndi mankhwala oyamba omwe amaperekedwa.
• Chithandizo cha immunoglobulin m'mitsempha (IVIg) chimaphatikizapo kupereka yankho lokhala ndi ma antibodies a anthu kudzera mu mitsempha. Ma antibodies atsopanowa amatha kumangirira ku ma antibodies olakwika a autoimmune ndikuwaletsa.

Ngati simukulandira bwino chithandizo chamankhwala wamba, dokotala wanu angayesere njira zina. Izi zikuphatikizapo:

• Ma antibodies a monoclonal , monga rituximab . Awa ndi ma antibodies opangidwa mu labu. Nthawi zina izi zimatha kuletsa chitetezo chamthupi. Dokotala wanu angakupatseni izi ngati mankhwala ena sagwira ntchito.
• Kuchotsa splenectomy . Pa milandu yoopsa, dokotala wanu angakulangizeni opaleshoni yochotsa ndulu yanu. ndulu yanu ndi komwe maselo akale a magazi amachotsedwa. Choncho ndulu ikachotsedwa, njirayi imachepa pang'ono.

Kodi pali zovuta zilizonse kapena zotsatirapo zina za chithandizochi?

Mukatenga mankhwala oletsa chitetezo chamthupi, chitetezo chamthupi chanu chimachepa. Komabe, chitetezo chanu ku matenda chimachepanso . Chifukwa chake muyenera kusamala kwambiri kuti musadwale.

Dokotala wanu angakulangizeni katemera wina kuwonjezera pa omwe mudalandira kale. Chitetezo cha mthupi lanu chikafooka (chosagwira ntchito bwino), mungakhale pachiwopsezo chachikulu cha matenda omwe simungalandire nthawi zambiri.

Kodi kukhala ndi Evans Syndrome kumakhudza moyo wa munthu?

Matenda a Evans Syndrome sakhudza moyo wanu wonse. Anthu ena amakhala ndi zizindikiro zochepa chabe, nthawi zina. Komabe, mavuto ena, monga kutuluka magazi, matenda a mtima, ndi matenda, akhoza kukhala pachiwopsezo chachikulu.

Ngati muli ndi matenda achiwiri a Evans, kutanthauza kuti muli ndi matenda ena osatha, zimenezo zingakhudzenso moyo wanu. Mungakhale ndi mavuto omwe angakupheni omwe amabwera chifukwa cha matenda ena.

Kodi chiyembekezo cha munthu amene ali ndi matenda a Evans Syndrome ndi chotani?

Zomwe anthu omwe ali ndi matenda a Evans Syndrome amakumana nazo zimasiyana kwambiri. Zizindikiro zimatha kukhala zochepa kapena zazikulu. Anthu ena amamva ngati zizindikiro zawo zimatha kwathunthu (kukhululuka). Ena amakumananso nazo pambuyo pake (kubwerera m'mbuyo).

Anthu ambiri amafunika chithandizo chamankhwala ndi kupimidwa nthawi zonse ndi dokotala. Mankhwala nthawi zambiri amagwira ntchito bwino, koma nthawi zina si nthawi zonse. Nthawi zina, mphamvu ya mankhwala ingaoneke ngati ikuchepa pakapita nthawi. Mungafunike kuyesa mankhwala ena.

Kodi ndimadzisamalira bwanji ndikakhala ndi matenda a Evans Syndrome?

Ngati muli ndi matenda a Evans Syndrome, ndikofunika kuti mupitirize kukaonana ndi dokotala nthawi zonse . Ngakhale mutakhala bwino, dokotala wanu adzafuna kuyang'anira vuto lanu ndikupeza msanga ngati likuipiraipira.

Komanso, nthawi zonse muyenera kudzisamalira nokha ndikuyang'anira zizindikiro zatsopano. Ngati muli ndi chimfine chomwe sichikuchira, kapena ngati muli ndi magazi osalamulirika, imbani dokotala nthawi yomweyo .

Ndi mafunso ati omwe ndiyenera kufunsa dokotala wanga?

Mungafune kufunsa dokotala wanu mafunso monga awa:

• Ndi mitundu iti ya maselo a magazi omwe ndikusowa?
• Kodi zachepa bwanji?
• Ndi zizindikiro ziti kapena machenjezo ati omwe ndiyenera kuyang'anitsitsa?
• Ndingadziwe bwanji ngati chithandizocho chikugwira ntchito kapena ayi?
• Kodi chimachitika ndi chiyani ngati chithandizocho sichikugwira ntchito?
• Kodi ndiyenera kulembetsa liti nthawi yotsatira kuti ndikakumane ndi dokotala?

Matenda a Evans ndi matenda osowa omwe mwina simunamvepo kale. Zizindikiro zake zingakhale zachilendo komanso zosokoneza. Kumvetsa zomwe zikuchitika ndi tanthauzo lake kungakhale kovuta pang'ono.

Ngakhale kuti matenda a Evans Syndrome ndi matenda omwe munthu amakhala nawo kwa moyo wake wonse, nthawi zina samakhala chimodzimodzi. Khalani ndi chiyembekezo chakuti mudzamva bwino, nthawi zina. Kaya mukumvera bwanji, gulu lanu lachipatala lidzakhalapo kuti likupatseni chithandizo chomwe mukufuna.

Uthenga Womaliza Wopita Nawo Kunyumba

Chabwino, tiyeni tikukumbutseni zina mwa zinthu zofunika kwambiri zomwe takambirana.

• Kodi Evans Syndrome ndi chiyani?Matenda osowa kwambiri omwe chitetezo cha mthupi lanu chimaukira maselo anu amagazi.
• Izi zingayambitse kuchepa kwa maselo ofiira a m'magazi ( anemia ), ma platelet (thrombocytopenia), ndipo mwina ma neutrophils (neutropenia) .
• Zizindikiro monga kutopa kwambiri, kufiira, kuvulala mosavuta, kutuluka magazi pafupipafupi, komanso matenda opatsirana pafupipafupi zimatha kuchitika.
• Ngakhale kuti palibe mankhwala athunthu a izi, zizindikiro zimatha kuthetsedwa ndi chithandizo .
• Ndikofunikira kwambiri kutsatira malangizo a dokotala nthawi zonse ndikusamala zizindikiro.
• Simuli nokha. Madokotala ndi okondedwa anu adzakuthandizani. Ndikofunikanso kukhala ndi chiyembekezo.

Ndikukhulupirira kuti izi zikuthandizani. Ngati muli ndi mafunso aliwonse, musazengereze kulankhula ndi dokotala wanu.

Matenda a Evans , matenda a autoimmune, cytopenia, kuchepa kwa magazi m'thupi, thrombocytopenia, neutropenia, matenda a magazi