Kodi kupweteka kwa m'mimba mwanu si kupweteka kwa m'mimba kokha? Tiyeni tikambirane za GIST (Gastrointestinal Stromal Tumor)!

Kodi nthawi zina mumavutika m'mimba, kapena m'mimba mumakhala ndi ululu, kapena mumadzimva kulemera? Nthawi zina timaganiza kuti chakudya ndi choipa, "kusokonezeka m'mimba", kapena kungoti "kutupa m'mimba". Koma, taganizirani izi, nthawi zina pakhoza kukhala nkhani yoopsa kwambiri kumbuyo kwa zizindikiro zazing'ono ngati zimenezi. Chimodzi mwa zizindikirozi, chomwe sichili chofala kwambiri, koma chofunikira kwambiri kudziwa za matenda a khansa ndi GIST, yomwe imayimira Gastrointestinal Stromal Tumor . Tiyeni tikambirane za izi mwatsatanetsatane, koma mwachidule, chabwino?

Kodi chotupa cha m'mimba (GIST) ichi n'chiyani?

Mwachidule, ma GIST ndi zotupa za khansa zomwe zimapangidwa m'makoma a kugaya chakudya —gawo la thupi lanu kumene chakudya ndi zakumwa zimayenda kuchokera pakamwa panu kupita m'mimba kenako n'kudutsa m'matumbo kuti zigayidwe. Zotupa zimenezi, kunena zoona, zimagwera mu zomwe madokotala amatcha ' soft tissue sarcoma.'

Tsopano taganizirani izi, zotupa zina za GIST ndi zazing'ono kwambiri, monga chofufutira pensulo kapena nandolo. Ngati ndi chotupa chaching'ono kwambiri, simungachizindikire kapena kumva kupweteka kulikonse. Komabe, zotupa zina zimayamba kukula pakapita nthawi. Pamenepo ndi pomwe ma GIST awa angayambe kukubweretserani zizindikiro zosiyanasiyana ndi mavuto ena azaumoyo. Nthawi zambiri, madokotala amachiritsa vuto la GIST mwa kuchita opaleshoni kuti achotse chotupacho kapena zotupa zonse.

Kodi vuto limeneli lotchedwa GIST ndi lofala bwanji?

Ndipotu, GIST ndi mtundu wa khansa wosowa kwambiri . Ngakhale poyerekeza ndi mayiko ena padziko lonse lapansi, ndi chimodzimodzi. Mwachitsanzo, m'dziko ngati United States, milandu yatsopano 4,000 mpaka 6,000 yokha ya GIST imapezedwa chaka chilichonse. Chifukwa chake mutha kulingalira momwe vutoli limakhalira losowa. Ndicho chifukwa chake ndikofunikira kudziwa za matendawa, kuti ngati muwona zizindikiro, mutha kufunsa upangiri wachipatala mwachangu.

Kodi zizindikiro za GIST ndi ziti?

Monga tanenera kale, ngati zotupa za GIST ndi zazing'ono kwambiri, simungaone zizindikiro zilizonse. Nthawi zambiri, chotupa cha GIST chimapezeka mwangozi panthawi yoyezetsa, monga kujambulidwa m'mimba, kapena opaleshoni ina.

Komabe, pamene chotupacho chikukulirakulira, kapena kutengera malo ake, zizindikiro zina zingawonekere. Izi ndi zizindikiro zodziwika kwambiri:

• Kumva kupweteka m'mimba kapena kusasangalala . Izi zitha kukhala kumva kukhuta kapena chinthu china chomwe chakumangika m'mimba mwanu.
• Magazi mu ndowe zanu kapena chomwe chikuwoneka ngati madontho a magazi mu ndowe zanu. Nthawi zina ndowe zimatha kukhala zakuda kwambiri, zomwe ndi chizindikiro cha kutuluka magazi mkati.
• Kudzimbidwa kumatanthauza kusachita chimbudzi kwa masiku angapo.
• Nthawi zonseKumva kutopa kwambiri komanso kutopa . Ngati kuti palibe moyo m'thupi.
• Kuchepetsa thupi popanda kuyesetsa.
• Kusowa chakudya kumatanthauza kusafuna kudya.
• Kusanza magazi . Ichi ndi chizindikiro choopsa pang'ono.

Ngati mwakhala mukukumana ndi chimodzi mwa zizindikiro izi kwa kanthawi, ndi bwino kupita kwa dokotala kukayezetsa, m'malo mongodzifunsa kuti, "N'chiyani chimenecho?"

Kodi zifukwa za GIST ndi ziti?

Nthawi zambiri, GIST imachitika pakakhala kusintha, kapena kusintha kwa majini otchedwa KIT m'thupi lathu. Taganizirani kuti jini iyi ya KIT ili ngati mthenga wamng'ono amene amauza maselo ena m'thupi lathu kuti "agawane ndikuchulukana." Chifukwa chake, pakakhala cholakwika mu jini iyi, maselo amenewo amayamba kugawikana ndikuchulukana mwachangu komanso mosalamulirika. Chotupa chimenecho, kapena GIST, chimapangidwa maselo amenewo akakula mosalamulirika. Kusintha kwa majini kumeneku kumachitika nthawi zambiri titabadwa, nthawi ya moyo wathu. Si chinthu chomwe chimalandira kuchokera kwa makolo kupita kwa ana.

Jini iyi ya KIT imauza maselo kuti apange puloteni yotchedwa KIT CD117 . Puloteni iyi imalimbikitsa kugawikana kwa maselo m'thupi. Mu GIST, njirayi imasokonekera, zomwe zimapangitsa kuti zotupa zipangidwe.

Komabe, ngakhale kuti sizichitika kawirikawiri, matenda ena obadwa nawo angawonjezere pang'ono chiopsezo cha matenda a GIST. Zina mwa matenda amenewa ndi monga:

• Matenda a Family GIST: Izi sizichitika kawirikawiri. Chomwe chimachitika apa ndi chakuti vuto la majini a KIT limatengera kuchokera kwa makolo kupita kwa ana. Ngati izi zitachitika, chiopsezo chotenga GIST chimawonjezeka. Komanso, GIST imatha kufalikira ali aang'ono kuposa masiku onse ndipo chotupa choposa chimodzi chingachitike.
• Mtundu woyamba wa Neurofibromatosis: Uwu ndi matenda a majini. Umayambitsa mitundu ina ya maselo kukula mosalamulirika ndikupanga zotupa m'mbali zosiyanasiyana za thupi. GIST ndi mtundu umodzi wa chotupa chomwe chingakule motere.
• Matenda a Carney-Stratakis: Uwu ndi matenda osowa kwambiri, obadwa nawo. Anthu omwe ali ndi vutoli ali pachiwopsezo chachikulu chotenga matenda a GIST kuposa ena.

Kodi matenda a GIST amachiritsidwa bwanji?

Mukapita kukaonana ndi dokotala yemwe ali ndi zizindikiro zomwe tatchula pamwambapa, choyamba adzakufunsani za zizindikiro zanu, nthawi yomwe zakhalapo, kenako adzakuyesani thupi . Izi zikutanthauza zinthu monga kukhudza m'mimba mwanu.

Kuphatikiza apo, dokotala wanu angafune mayeso ena angapo kuti atsimikizire ngati muli ndi GIST, kukula kwake, komanso ngati yafalikira. Zofunikira kwambiri ndi izi:

• Endoscopy yapamwamba:Izi zimaphatikizapo kulowetsa chubu chokhala ndi kamera kakang'ono kudzera pakamwa panu ndikuyang'ana mkati mwa pakhosi panu, m'mero ​​(chitoliro cha chakudya), ndi m'mimba. Izi zimakupatsani mwayi wowona mwachindunji ngati pali chilichonse, monga chotupa.
• Kujambula kwa CT: Izi zimagwiritsa ntchito X-rays kujambula zithunzi zamkati mwa mimba yanu. Izi zingathandize kudziwa kukula ndi malo a chotupacho.
• Kujambula kwa positron emission tomography (PET): Uku ndi mtundu wapadera wa kujambulidwa. Kumathandiza kudziwa momwe maselo a khansa alili ogwira ntchito komanso ngati afalikira mbali zina za thupi.
• Biopsy: Iyi ndi njira yoyesera yomwe imagwiritsidwa ntchito kutsimikizira ngati muli ndi GIST. Izi zimaphatikizapo kutenga chidutswa chaching'ono kwambiri cha minofu kuchokera pa chotupacho ndikuchiyang'ana pansi pa maikulosikopu ndi katswiri wa matenda . Izi zithandiza kudziwa ngati ndi GIST kapena china chake. Nthawi zina biopsy imatha kuchitidwa nthawi yomweyo ndi endoscopy.

Kodi GIST imachiritsidwa bwanji?

Munthu wamkulu amene amachiritsa GIST ndi katswiri wa khansa . GIST nthawi zambiri amachiritsidwa ndi opaleshoni kuti achotse chotupacho. Komabe, mtundu wa chithandizo choyenera kwa inu umadalira zomwe mayeso apeza. Izi zikutanthauza kuti madokotala adzayang'ana zinthu monga kukula kwa chotupacho, komwe chili, komanso ngati chafalikira (chofalikira) kuchokera komwe chinayambira.

Mwachitsanzo:

• Ngati chotupacho chili chaching'ono kwambiri, dokotala wanu wa khansa akhoza kuchichotsa kwathunthu ndi opaleshoni. Kenako, palibe chithandizo china chomwe chingafunike.
• Koma ngati chotupacho ndi chachikulu kwambiri kapena chili pamalo ovuta kuchichita opaleshoni, dokotala wanu wa khansa angasankhe kukupatsani mankhwala otchedwa targeted therapy kuti achepetse chotupacho musanachite opaleshoni. Mankhwalawa amalimbana ndi zinthu zinazake zomwe zimathandiza maselo a GIST kukula. Izi zimachepetsa chotupacho ndipo zimapangitsa kuti chikhale chosavuta kuchichita opaleshoni. Nthawi zina, njira zochizira izi zimatha kupitilizidwa pambuyo pa opaleshoni kuti GIST isabwererenso.

Kumbukirani, si odwala onse a GIST omwe amalandira chithandizo chofanana. Gulu lanu lachipatala lidzakambirana nanu za njira yabwino kwambiri yothandizira matenda anu.

Kodi zotsatirapo zake ndi ziti?

Monga momwe zimakhalira ndi chithandizo chilichonse chamankhwala, chithandizo cha GIST chingayambitse zotsatirapo zina.

Zotsatira zina zomwe zingakhalepo chifukwa cha chithandizo cholunjika:

• Kutsekereza
• Kutsegula m'mimba (kupweteka m'mimba)
• Kutopa ndi kutopa
• Kupweteka kwa minofu
• Kumva ngati kusanza (kumva ngati kusanza)

Zotsatira zoyipa zomwe zingachitike panthawi ya opaleshoni:

• Kuyankha kwa mankhwala oletsa ululu (monga chizungulire, kusanza)
• Ululu pamalo ochitira opaleshoni
• Kutuluka magazi

Zotsatira zoyipa izi sizimachitikira aliyense mofanana. Anthu ena angakumane ndi zingapo mwa izo, pomwe ena sangakumane nazo. Ngati mukumva kusasangalala kulikonse, onetsetsani kuti mwauza dokotala kapena namwino wanu. Zotsatira zoyipa zambiri zimatha kuthetsedwa.

Kodi ndiyenera kuyembekezera chiyani pambuyo pake ngati ndili ndi GIST?

Ngakhale chithandizo chitatha, dokotala wanu wa khansa adzapitiriza kukuyang'anirani. Izi zikutanthauza kuti mudzapemphedwa kuti mubwere kudzakumana ndi dokotala nthawi ndi nthawi kuti muwone ngati mukuchira komanso ngati muli ndi thanzi labwino. Nthawi zambiri nthawi zambiri mumakhala miyezi itatu kapena isanu ndi umodzi iliyonse.

Pa maulendo amenewa, dokotala wanu adzakufunsani za zizindikiro zanu, adzakuyesani, ndipo angachitenso mayeso ena, monga ma scan, kuti aone ngati GIST yabwerera kapena momwe ikugwirira ntchito mukalandira chithandizo. Mayeso ofala ndi awa:

• Kujambula kwa CT kwa chiwindi ndi chiuno.
• Kujambula kwa MRI (Magnetic resonance imaging (MRI) scans) .
• PET scan kuti ione momwe mankhwala ochiritsira amagwirira ntchito.

Dokotala wanu adzasankha nthawi yomwe muyenera kuyezetsa izi, kutengera matenda anu.

Kodi chiŵerengero cha kupulumuka ndi GIST ndi chiyani?

Nkhaniyi ndi yovuta kwambiri. Kuchuluka kwa moyo wa munthu amene ali ndi GIST kumasiyana malinga ndi munthu. Pali zinthu zingapo zomwe zimapangitsa kuti izi zidziwike. Mwachitsanzo, kukula kwa chotupacho pamene GIST yapezeka, momwe imagwirira ntchito, thanzi lanu lonse, komanso momwe chotupacho chimayankhira chithandizo.

Malinga ndi deta yomwe yasonkhanitsidwa kuchokera ku mabungwe monga US National Cancer Institute (NCI) , pafupifupi 85% ya anthu omwe ali ndi GIST akadali ndi moyo zaka zisanu kuchokera pamene matendawa adapezeka.

Komabe, mukawona ziwerengero ngati izi, muyenera kukumbukira zinthu zingapo:

• Izi ndi ziwerengero chabe: zimachokera ku zomwe anthu ambiri adakumana nazo kale ndi GIST. Mkhalidwe wanu ukhoza kukhala wosiyana kwambiri. Mwachitsanzo, zaka zanu komanso ngati muli ndi matenda ena zingakhudze ziwerengerozi.
• Manambala awa ndi akale: deta imasonkhanitsidwa pafupifupi zaka zisanu zilizonse. Chifukwa chake, zotsatira za mankhwala aposachedwa sizikuphatikizidwa mu manambala awa. Ndi mankhwala atsopano, manambalawa akhoza kukhala abwino kwambiri.
• Chiwerengero cha anthu omwe ali ndi matenda a shuga ndi chiwerengero cha anthu omwe ali ndi matenda a shuga ndi zinthu ziwiri zosiyana: Chiwerengero cha anthu omwe ali ndi matenda a shuga sichikudziwitsani nthawi yomwe mudzakhala ndi moyo. Deta ya anthu omwe ali ndi matenda a shuga ndi yovuta kwambiri kupeza kwa anthu omwe ali ndi matenda a shuga.

Choncho, musavutike ndi ziwerengerozi. Ngati muli ndi mafunso, funsani dokotala wanu wa khansa. Iye adzatha kufotokoza momwe ziwerengerozi zikugwirira ntchito pa vuto lanu.

Kodi mumadzisamalira bwanji?

Kusamalira thanzi lanu lonse ndiye chinthu chabwino kwambiri chomwe mungachite nokha, panthawi ya chithandizo cha GIST komanso pambuyo pake.

• Idyani bwino: Yesetsani kudya zakudya zosiyanasiyana zomwe zili ndi mapuloteni ambiri, mafuta ochepa, komanso momwe mungathere. Phatikizani masamba, ndiwo zamasamba, ndi zipatso muzakudya zanu za tsiku ndi tsiku. Zakudya zoyenera zidzapatsa thupi lanu mphamvu kuti lichire msanga.
• Chitani masewera olimbitsa thupi: Kudwala kungakhale kovuta. Pamene mukuchira kuchokera ku chithandizo, kuchita masewera olimbitsa thupi pang'ono (monga kuyenda) kungakuthandizeni kuchepetsa nkhawa. Komabe, nthawi zonse muyenera kulankhula ndi dokotala wanu musanayambe kuchita masewera olimbitsa thupi atsopano kapena musanayambe kuchita masewera olimbitsa thupi omwe mumachita.
• Pewani kusuta fodya konse: Kugwiritsa ntchito fodya wamtundu uliwonse (kuphatikizapo ndudu zamagetsi) kumawonjezera chiopsezo chotenga khansa yatsopano, komanso chiopsezo cha GIST kubwereranso.

Matenda ngati GIST sangayambitse zizindikiro zazikulu poyamba. Ngakhale mutatero, mungaganize kuti ndi vuto la kusadya bwino kapena chimfine cha m'mimba. Chifukwa chake, kudziwa kuti muli ndi chotupa cha khansa chosowa chonga ichi kungakhale kodabwitsa kwambiri. Ngati muli ndi vutoli, tengani nthawi yophunzira za matenda osowa awa ndi njira zomwe mungasankhire. Nthawi zambiri, chithandizo chingachepetse zizindikiro zanu komanso kuchiritsa GIST. Mudzakhala ndi mafunso ambiri. Gulu lanu lachipatala lidzakhalapo kuti liyankhe onse ndikukuthandizani.

Pomaliza, zinthu zoti muzikumbukira

Ngakhale kuti GIST ndi chinthu choopsa, ndi vuto lomwe lingakhale ndi zotsatira zabwino ngati mutadziwa ndi kulandira chithandizo chamankhwala nthawi yake.

• Musanyalanyaze: Ngati muli ndi ululu wa m'mimba wosazolowereka, zizindikiro za kutuluka magazi, kapena kuchepa thupi kosayembekezereka, funsani upangiri kwa dokotala.
• Kuzindikira matenda molondola n'kofunika: Mayeso apadera amafunika kuti mupeze matenda a GIST. Chifukwa chake, funsani maganizo a katswiri.
• Pali mankhwala: Pali mankhwala othandiza a GIST, monga opaleshoni ndi chithandizo cholunjika.
• Simuli nokha: gulu lanu lachipatala, banja lanu, ndi anzanu adzakuthandizani paulendowu.

Chofunika kwambiri ndikukhala olimba mtima ndikutsatira malangizo a dokotala.

Chotupa cha m'mimba , GIST, khansa, dongosolo la m'mimba, jini la KIT, opaleshoni, chithandizo cholunjika