Kodi tiyenera kuphunzira za H2 Blockers pa kutentha pamtima ndi gastritis?

Kodi nthawi zina mumamva kuwonjezeka kwa asidi m'mimba, kutentha pamtima, kapena kusasangalala m'mimba mukatha kudya? Kapena muli ndi vuto ngati gastritis? Ndiye mwina mwamvapo za mtundu wa mankhwala otchedwa H2 blockers. Lero, tiyeni tikambirane za zomwe H2 blockers izi zilili, momwe zimagwirira ntchito, komanso momwe zimagwiritsidwira ntchito.

Kodi ma H2 blockers (otsutsana ndi H2) ndi chiyani?

Mwachidule, H2 blockers ndi mtundu wa mankhwala omwe amachepetsa kuchuluka kwa asidi wopangidwa m'mimba mwanu. Tsopano mwina mukudabwa kuti asidi wa m'mimba ndi wotani. Asidi wa m'mimba ndi wofunikira kwambiri pogaya chakudya chomwe timadya. Komabe, mavuto amayamba pamene asidi uyu wakula kwambiri. Kenako minofu yofewa ya dongosolo lathu logaya chakudya (GI - m'mimba) imatha kuwonongeka. Ichi ndichifukwa chake zizindikiro monga kupweteka m'mimba ndi kutentha pamtima zimachitika. Nthawi zina, kudya chakudya chokometsera kungakhale kovuta kwambiri moti mungaganize kuti, "O, n'chifukwa chiyani ndadya zimenezo?"

Choncho, ngati muli ndi zizindikiro zoyambitsidwa ndi kuchuluka kwa asidi m'mimba, mungafune kuganizira zogwiritsa ntchito H2 blocker.

Ndi matenda ati omwe amachiritsidwa ndi H2 blockers?

Mankhwala oletsa H2 amagwiritsidwa ntchito makamaka pochiza matenda okhudzana ndi kuchuluka kwa asidi m'mimba. Koma chinthu chimodzi choyenera kukumbukira: Mukapitiliza kugwiritsa ntchito mankhwalawa, mphamvu yawo ingachepe pang'onopang'ono pakapita nthawi.

Ngati muli ndi vuto lalikulu komanso la nthawi yayitali lomwe limakhudza asidi wambiri m'mimba, mungafune kuganizira za mtundu wa mankhwala otchedwa proton pump inhibitor (PPI) . Ngakhale kuti ma PPI sagwira ntchito mwachangu ngati ma H2 blockers, amachepetsanso kupanga asidi m'mimba ndipo angagwiritsidwe ntchito kwa nthawi yayitali kuposa ma H2 blockers. Ma PPI ndi mtundu wa mankhwala omwe ali ndi mphamvu kwambiri polamulira asidi kuposa ma H2 blockers.

Tiyeni tiwone zina mwa matenda akuluakulu omwe amachiritsidwa ndi H2 blockers:

Zilonda zam'mimba ndi zilonda za duodenal

Asidi m'mimba akakwera kwambiri, amatha kuwononga mkati mwa m'mimba ndikuyambitsa zilonda. Mankhwala oletsa H2 amachepetsa kupanga asidi m'mimba, zomwe zimapatsa zilondazi nthawi yoti zichiritsidwe.

Komanso, asidi m'mimba nthawi zina amatha kupita ku gawo loyamba la matumbo athu ang'onoang'ono (duodenum) ndikuyambitsa zilonda kumeneko. Timazitcha zilonda zam'mimba . Ngakhale kuti ma PPI ndiye mankhwala othandiza kwambiri pa izi, ma H2 blockers amathanso kuchiza vutoli. US Food and Drug Administration (FDA) yavomereza ma H2 blockers kuti agwiritsidwe ntchito posamalira kwakanthawi kochepa kuti apewe zilonda zatsopano. Dokotala wanu akhoza kukulankhulani za chithandizo choyenera komanso njira yosamalira.

Reflux ya asidi ndi GERD

Ili ndi vuto lomwe anthu ambiri ali nalo. Kubwerera m'mbuyo kwa asidi m'thupi.Zimatanthauza kuti asidi m'mimba amabwereranso mmwamba, kutanthauza kuti, amakwera, ndikulowa pakhosi kudzera mu m'mero ​​(chitoliro cha chakudya). Izi ndi zomwe zimayambitsa kutentha pamtima. Ngati vutoli likupitirira, kutupa kwa m'mero ​​(esophagitis) kungachitikenso. Choletsa H2 chingapereke mpumulo pa nthawi zina za m'mero. Koma ngati muli ndi vuto la m'mero ​​la asidi nthawi yayitali, kutanthauza GERD (Gastroesophageal Reflux Disease) , kungakhale bwino kugwiritsa ntchito PPI.

Matenda a Zollinger-Ellison

Imeneyi ndi vuto losowa kwambiri. Limachitika pamene zotupa zina m'thupi mwathu zimapangitsa kuti m'mimba mwathu mutulutse asidi wambiri. Mankhwala oletsa H2 angathandize poletsa kupanga asidi m'mimba. Komabe, pankhaniyi, dokotala wanu mwina angakulembereni PPI.

Zizindikiro zimachepa ndi H2 blockers

Mankhwalawa angathandize kuchepetsa zizindikiro zotsatirazi:

• Kutupa, kusadya bwino
• Kupweteka m'mimba
• Kutentha pamtima ndi reflux
• Kusanza ndi kusanza
• M'mimba wowawasa, kukoma kowawasa pakhosi

Kodi ma H2 blockers amagwira ntchito bwanji?

Dzina lina la ma H2 blockers ndi ma histamine-2 (H2) antagonists . Dzinali limatipatsa lingaliro laling'ono la momwe mankhwalawa amagwirira ntchito. Mwina munaphunzirapo za udindo wa 'wotsutsa' m'kalasi la Chingerezi pamene munali kusukulu. Mu chiganizo, wotsutsa ndi chinthu chomwe chimayambitsa kutsekeka. Mofananamo, ma H2 antagonists amaletsa kupanga asidi m'mimba.

Taganizirani izi motere. Mukadya chakudya, thupi lanu limatulutsa mankhwala otchedwa H2. H2 iyi imapita ndi kumamatira ku malo enaake (ma H2 receptors) pa maselo omwe ali m'makoma a mimba yanu. Kumatirira kumeneku ndi komwe kumapangitsa kuti mimba yanu itulutse asidi.

Mukatenga mankhwala oletsa H2, kapena H2 blocker, mankhwalawa amapita ku ma H2 receptors H2 isanawamangirire. Mwachidule, ma H2 blockers "amaletsa" H2 kuti isamamangirire ku ma receptor amenewo. Izi zimachepetsa kupanga asidi m'mimba.

Izi sizingasokoneze kugaya kwanu chakudya. Koma zichepetsa kuchuluka kwa asidi wowonjezera womwe umayambitsa zizindikiro zopwetekazo. Mwamvetsa?

Kodi mitundu ya mankhwala oletsa H2 ndi iti? (Mankhwala omwe alipo pamsika)

Pali mitundu ingapo ya mankhwala oletsa H2. Ena mungawagule pa sitolo ya mankhwala (OTC) ku pharmacy popanda mankhwala (Rx). Ena amafunika mankhwala ochokera kwa dokotala. Izi zimasiyana malinga ndi mtundu wa mankhwala ndi mlingo wake.

Mitundu ya ma H2 blockers omwe alipo pano ndi awa:

• Cimetidine ( dzina la mtundu, mwachitsanzo, Tagamet®) - Izi zikupezeka pa OTC ndi Rx.
• Famotidine(Dzina la kampani, mwachitsanzo, Pepcid®) - Izi zikupezekanso OTC ndi Rx.
• Nizatidine (dzina la mtundu, mwachitsanzo, Axid®) - Izi zitha kupezeka pokhapokha ndi Rx.

Mwina munamvapo za Ranitidine ( yomwe imadziwika ndi dzina la Zantac®). Inali mankhwala oyamba oletsa H2 omwe adavomerezedwa ndi FDA mu 1983. Komabe, mu Epulo 2020, FDA idalamula opanga kuti achotse Ranitidine pamsika. Chifukwa cha izi chinali chakuti mayeso a FDA adapeza kuti Ranitidine ikasungidwa kwa nthawi yayitali, kuchuluka kwa khansa yomwe ingayambitse khansa (nitrosodimethylamine, kapena NDMA) kumawonjezeka kufika pamlingo wosatetezeka. Ofufuza adapezanso kuti kuchuluka kwa NDMA kumawonjezeka Ranitidine ikasungidwa kutentha kwambiri.

Kodi mankhwalawa angagwiritsidwe ntchito bwanji?

Mankhwala ambiri oletsa H2 amabwera ngati mapiritsi kapena makapisozi omwe mumamwa. Nthawi zina amabweranso ngati ufa womwe mungasakanize ndi madzi ndikumwa kwa anthu omwe amavutika kumeza mapiritsi.

Mankhwala ena oletsa H2 angaperekedwenso kudzera m'mitsempha (IV) , makamaka ngati muli m'chipatala ndipo simungathe kumwa mankhwalawo pakamwa.

Kodi nthawi yabwino yogwiritsira ntchito H2 blocker ndi iti?

Ngati mukudziwa kuti mudya chinthu chomwe simukuchikonda, monga chakudya chokometsera, ndi bwino kumwa mankhwala oletsa H2 kwa mphindi 30 mpaka 60 musanadye . Mwanjira imeneyi, mankhwalawa amakhala ndi nthawi yoti ayambe kugwira ntchito. Palibe vuto kumwa mukamaliza kudya, koma zingatenge ola limodzi kuti zizindikiro zanu zichepe.

Monga chithandizo cha kanthawi kochepa cha vuto monga zilonda zam'mimba, dokotala wanu angakuuzeni kuti mumwe mankhwalawa motere:

• Kamodzi patsiku, musanagone usiku.
• Kapena kamodzi m'mawa ndi kamodzi usiku.

Chofunika kwambiri ndichakuti ngati mukufuna kugwiritsa ntchito H2 blocker kwa milungu yoposa iwiri kuti muchepetse zizindikiro zanu, muyenera kuwonana ndi dokotala. Si bwino kudalira H2 blocker kwa nthawi yayitali popanda kulankhula ndi dokotala.

Kodi zimatenga nthawi yayitali bwanji kuti mankhwala oletsa H2 agwire ntchito? Kodi amasiyana bwanji ndi mankhwala ena?

Nthawi zambiri zimatenga pafupifupi ola limodzi kuti mumve mpumulo ku zizindikiro mutamwa mankhwala oletsa H2. Zotsatira zake nthawi zambiri zimatenga maola anayi mpaka khumi . Kuchitapo kanthu mwachangu kumeneku kumapangitsa kuti ikhale chisankho chabwino ngati mukufuna mpumulo mwachangu kapena ngati muli ndi kutentha pamtima nthawi zina.

Ngati mukufuna mpumulo wofulumira kwambiri, mutha kuyesa mankhwala oletsa asidi . Mankhwala oletsa asidi amachotsa asidi m'mimba mwanu. Amayamba kugwira ntchito mofulumira kuposa mankhwala oletsa H2, koma zotsatira zake sizingakhale nthawi yayitali ngati mankhwala oletsa H2.

Ngati zizindikiro zanu zimakhala zokhalitsa, makamaka ngati mankhwala oletsa H2 sakukupatsani mpumulo wokwanira, mungafunike kumwa PPI. PPI imatha kutenga tsiku limodzi mpaka anayi kuti igwire ntchito mokwanira, koma imatenga nthawi yayitali kuposa mankhwala oletsa H2.

Kodi ma H2 blockers ali ndi zotsatirapo zoyipa?

Mankhwala oletsa H2 amathandiza kuchepetsa chiopsezo cha zotsatirapo zoyipa. Komabe, monga mankhwala ena aliwonse, zotsatirapo zazing'ono zimatha kuchitika.

Zotsatira zoyipa zofala

• Kupweteka m'mimba
• Kupweteka kwa minofu
• Kudzimbidwa
• Kutsegula m'mimba (kudzimbidwa m'mimba)
• Pakamwa pouma
• Kutopa
• Mutu

Zinthu zofunika kuziganizira kwambiri

Ngakhale kuti sizichitika kawirikawiri, mankhwala oletsa H2 angayambitse zizindikiro za mitsempha (monga chisokonezo, kulankhula molakwika) m'magulu ena omwe ali pachiwopsezo chachikulu. Muli ndi mwayi wokumana ndi zizindikirozi ngati muli ndi zaka zoposa 50 ndipo impso kapena chiwindi chanu chachepa . Komabe, zizindikirozi nthawi zambiri zimatha patangopita masiku ochepa mutasiya kumwa mankhwalawo.

Kodi pangakhale mavuto ndi mankhwala ena?

Mankhwala ena oletsa H2 (monga cimetidine) amatha kuletsa mankhwala ena omwe mukumwa kuti asagwire bwino ntchito. Mwachitsanzo, cimetidine imatha kuchepetsa mphamvu ya ma SSRI ena (mtundu wa mankhwala omwe amagwiritsidwa ntchito pochiza matenda amisala monga kuvutika maganizo) ndi warfarin (mankhwala omwe amaletsa magazi kuundana).

Choncho, musanayambe mankhwala atsopano, ndikofunikira kwambiri kulankhula ndi dokotala wanu kuti mudziwe ngati pali vuto lililonse ndi mankhwala omwe mukumwa kale.

Kodi kugwiritsa ntchito mankhwala oletsa H2 pa nthawi ya mimba ndi kuyamwitsa n'kotetezeka?

Kafukufuku wowonjezereka akufunika kuti adziwe chitetezo chogwiritsa ntchito mankhwala oletsa H2 panthawi ya mimba, koma ofufuza akudziwa kuti mankhwalawa amalowa mkaka wa m'mawere .

Ngati mukumwa mankhwala oletsa H2 ndipo muli ndi pakati, onetsetsani kuti mwalankhula ndi dokotala wanu. Mufunseni ngati kuli kotetezeka kumwa mankhwalawa panthawi yapakati kapena mukuyamwitsa.

Kodi muyenera kupita kwa dokotala liti?

Monga tanenera kale, ngati mukuyenera kugwiritsa ntchito mankhwala oletsa H2 kwa milungu yoposa iwiri kuti muchepetse zizindikiro zanu, muyenera kuonana ndi dokotala. Ndikofunikira kudziwa chomwe chikuyambitsa zizindikiro zanu. Mungafunike njira yothetsera vutoli kwa nthawi yayitali, monga PPI.

Komanso, uzani dokotala wanu ngati muli ndi zotsatirapo zilizonse zoipa chifukwa cha mankhwalawo kapena ngati mwaona zotsatirapo zina. Mlingo wanu ungafunike kusinthidwa kapena mungafunike kusintha mankhwala ena.

Kodi choletsa H2 chotetezeka kwambiri ndi chiyani? Kodi chabwino kwambiri pa GERD ndi chiyani?

Mankhwala oletsa H2 ovomerezedwa ndi FDA ndi ofanana kwambiri pankhani ya chitetezo ndi mphamvu zawo.

Komabe, ngati mukumwa mankhwala ena ndipo mukuganiza zogwiritsa ntchito mankhwala oletsa H2, ndi bwino kulankhula ndi dokotala wanu. Ndikofunikira kusankha mankhwala omwe sangasokoneze mphamvu ya mankhwala omwe mukumwa kale.

Kwa GERD, choletsa chilichonse cha H2 chingathandize kuchepetsa zizindikiro za acid reflux. Komabe, ngati acid reflux yanu ndi yosatha (monga momwe zilili ndi GERD), kungakhale bwino kusiya kugwiritsa ntchito H2 blockers konse ndi kusankha PPI. Lankhulani ndi dokotala wanu za izi.

Pomaliza, zinthu zoti muzikumbukira (Uthenga Wopita Nawo Kunyumba)

Chabwino, lero takambirana zambiri za ma H2 blockers, sichoncho?

Mankhwala oletsa H2, mankhwala oletsa asidi, ndi ma PPI onse amagwiritsidwa ntchito pochiza matenda omwe amayamba chifukwa cha asidi wambiri m'mimba. Nthawi zina, ndi njira zambiri, zimakhala zosokoneza kudziwa chomwe mungasankhe.

Ganizirani izi motere: Ngati mukufuna mpumulo wa kanthawi kochepa womwe umatenga maola angapo, mankhwala oletsa H2 angakhale njira yabwino kwambiri kwa inu. Makamaka ngati mukudziwa kuti mungakhale ndi kutentha pamtima mutadya chinthu chokometsera, ndi bwino kumwa mankhwala oletsa H2 musanayambe.

Kumbukirani, ngati muli ndi mafunso ena okhudza mankhwalawa, musaope kufunsa dokotala wanu. Ndikofunikira kwambiri kudziwa za thanzi lanu!

Mankhwala oletsa H2 , gastritis, kutupa m'mimba, asidi m'mimba, kutupa pachifuwa, zilonda zam'mimba, nkhani zachipatala za ku Sinhala