Kodi muli ndi hormone ya prolactin yambiri m'thupi lanu? Tiyeni tikambirane za hyperprolactinemia!

Kodi munayamba mwadzifunsapo kuti zingachitike bwanji ndi kusintha pang'ono kwa mahomoni ena m'thupi lanu? Umenewo ndi vuto lomwe tikambirane lero, lotchedwa hyperprolactinemia. Mwachidule, izi zimachitika pamene magazi anu ali ndi mahomoni ambiri otchedwa prolactin. Homoni iyi imayambitsa kukula kwa mawere ndi kupanga mkaka. Vutoli silikuika moyo pachiswe, koma nthawi zina lingayambitse mavuto monga kusabereka komanso kusokoneza kuthekera kwanu kukhala ndi moyo wabwinobwino. Koma nkhani yabwino ndi yakuti pali mankhwala ake.

Kodi vutoli ndi lofala bwanji?

Ndipotu, vuto limeneli lotchedwa hyperprolactinemia si lofala kwambiri. Limakhudza anthu osakwana 1% mwa anthu onse. Komabe, akazi ndi omwe ali ndi mwayi waukulu wopeza vutoli kuposa amuna.

Kodi zizindikiro za izi ndi ziti?

Kumbukirani kuti anthu ena akhoza kukhala ndi hyperprolactinemia koma osawonetsa zizindikiro zilizonse, kapena zizindikirozo zingakhale zochepa kwambiri. Komabe, pali zizindikiro zingapo zomwe zimachitika ndi vutoli, mosasamala kanthu za munthuyo.

Zizindikiro zofala zomwe zimakhudza aliyense

Izi zitha kuchitika mwa aliyense, mosasamala kanthu za jenda:

• Kuvuta kukhala ndi ana (kusabereka) : Ili ndiye vuto lalikulu.
• Kuchepa kwa chilakolako cha kugonana : Izi zikutanthauza kuchepa kwa chidwi cha kugonana.
• Kuchepa kwa mafupa (osteopenia) : Izi zingayambitse mafupa kufooka pakapita nthawi.
• Kutuluka kwa mkaka m'mabele mukakhala kuti simuli ndi pakati kapena mukuyamwitsa (`galactorrhea`) : Izi zingamveke zachilendo pang'ono, komanso ndi chizindikiro.

Makhalidwe apadera kwa akazi

Kwa akazi, kuwonjezera pa zizindikiro izi zodziwika bwino, zizindikiro zina zingapo zitha kuchitika:

• Kusintha kwa msambo sikukhudzana ndi kusamba kwa mwezi (kutha kwa msambo wa mwezi) : Izi zikutanthauza kuti msambo umakhala wosakhazikika kapena umatha kwathunthu. Simungakhale ndi msambo kwa miyezi ingapo.
• Ululu panthawi yogonana chifukwa cha kuuma kwa nyini : Ichi ndi chinthu chomwe chimakhumudwitsa akazi ambiri.

Makhalidwe enieni kwa amuna

Matendawa amakhudza amuna mosiyana. Nazi zizindikiro zina zomwe zimawachitikira:

• Kulephera kwa chiberekero (ED) : Izi zikutanthauza kuti zimavuta kukoka.
• Kuchepa kwa testosterone : Iyi ndi mahomoni ofunikira kwambiri m'thupi la mwamuna.
• Kukula kwa bere (`gynecomastia`) : Kukula kwa bere la mwamuna kuti lifanane ndi la mkazi.

N’chifukwa chiyani izi zikuchitika? Kodi zifukwa zake ndi ziti?

Chabwino, tsopano tiyeni tiwone chifukwa chake kuchuluka kwa prolactin kumawonjezeka motere. Pakhoza kukhala zifukwa zingapo.

• ProlactinomaIchi ndiye chifukwa chachikulu. `(Prolactinoma)` ndi chotupa chosakhala khansa (chosaopsa) (`adenoma`) chomwe chimayamba mu `(pituitary gland)` muubongo mwanu. Chotupachi chimapangitsa kuti hormone ya prolactin ipangidwe mopitirira muyeso.
• Ziphuphu zina za pituitary : Kuwonjezera pa prolactinoma, zotupa zina zazikulu zomwe zili mkati kapena pafupi ndi pituitary gland zingayambitsenso kuchuluka kwa prolactin. Izi zimachitika chifukwa chotupacho chimaletsa kutulutsa mankhwala otchedwa dopamine kupita ku pituitary gland. Dopamine ndi mahomoni omwe amalamulira kupanga prolactin.
• Mankhwala ena : Mankhwala otchedwa dopamine amachepetsa kupanga prolactin. Chifukwa chake, mankhwala aliwonse omwe amakhudza kupanga dopamine amatha kuwonjezera kuchuluka kwa prolactin m'thupi lanu. Ena mwa mankhwalawa ndi awa:
• Mapiritsi oletsa kubereka
• Mankhwala ena a matenda amisala, monga Risperidone ndi Haloperidol
• Mankhwala ochizira kuthamanga kwa magazi, monga methyldopa ndi verapamil
• Mankhwala a kutentha pamtima ndi matenda a gastroesophageal reflux (GERD) (monga mankhwala oletsa antihistamine a H2)
• Mankhwala ochizira kuvutika maganizo, monga tricyclic antidepressants ndi SSRIs
• Mankhwala a zizindikiro za kusamba, monga chithandizo cha estrogen
• Mankhwala oletsa nseru ndi kusanza (mankhwala oletsa kutsekula m'mimba)
• Mankhwala opha ululu okhala ndi ma opioid

Chofunika : Muyenera kulankhula ndi dokotala musanasiye kumwa mankhwala aliwonse omwe mukumwa. Nthawi zambiri kuchuluka kwa prolactin kumabwerera mwakale mkati mwa masiku atatu kapena anayi mutasiya kumwa mankhwalawo.

• Matenda ena : Ngakhale popanda prolactinoma, matenda ena angayambitse kuchuluka kwa prolactin m'thupi. Matendawa ndi monga:
• Kuvulala pachifuwa pakhoma (monga kusweka kwa nthiti)
• Matenda a impso osatha
• Matenda a chiwindi osatha
• Matenda a Cushing
• Hypothyroidism (chithokomiro chosagwira ntchito mokwanira)
• Herpes zoster (ma shingles), makamaka ngati matuza/madontho aonekera pachifuwa
• Matenda a ovary a Polycystic (PCOS)

Nanga bwanji ngati simungapeze chifukwa?

Nthawi zina madokotala sangapeze chifukwa cha izi. Zikatero, zimatchedwa "idiopathic hyperprolactinemia." Izi nthawi zambiri zimatha popanda chithandizo mkati mwa miyezi ingapo.

Kodi zinthu zoopsa ndi ziti?

Chinthu chokhacho chodziwika bwino chomwe chimayambitsa hyperprolactinemia ndi matenda otchedwa Multiple endocrine neoplasia (MEN) type 1 (MEN1). MEN1 ndi matenda obadwa nawo omwe angayambitse kukula kwa prolactinoma.

Ngati wina m'banja mwanu (mchimwene, mlongo, kholo) ali ndi `MEN1`, ndi bwino kupita kukayezetsa majini. Izi zingathandize kuzindikira `(Prolactinoma)` msanga.

Kodi mumazindikira bwanji izi molondola?

Ngati muli ndi zizindikiro izi, chinthu choyamba chomwe dokotala angachite ndikuchita mayeso a magazi a prolactin (PRL).

Ngati zotsatira zake zikutsimikizira kuti muli ndi hyperprolactinemia, sitepe yotsatira ndikupeza chomwe chikuyambitsa vutoli. Dokotala wanu angakupatseni mayeso ena a magazi ndi zithunzi (monga MRI scan).

Kodi mankhwala ake ndi otani?

Chithandizo chimadalira chomwe chimayambitsa matendawa. Ngati kuchuluka kwa prolactin m'magazi anu kuli kokwera koma zizindikiro zanu sizili zotsika, simungafunike chithandizo.

Chithandizo cha prolactinoma

Ichi ndi chifukwa chofala kwambiri. Chifukwa chake pali njira zingapo zochizira:

• Mankhwala : Mankhwala a dopamine agonists amawongolera kuchuluka kwa prolactin m'thupi lanu. Mankhwalawa ndi othandiza kwambiri pochepetsa zotupa za prolactinoma. Uwu ndiye mankhwala omwe amagwiritsidwa ntchito kwambiri pa prolactinoma.
• Opaleshoni : Ngati prolactinoma siichepa ndi mankhwala, opaleshoni ingafunike kuti ichotsedwe.
• Chithandizo cha radiation : Iyi ndi njira yachitatu yomwe imagwiritsidwa ntchito kawirikawiri. Imagwiritsidwa ntchito pokhapokha ngati njira zina sizikugwira ntchito.

Ngati ndi chifukwa cha mankhwala...

Ngati zapezeka kuti kuchuluka kwa prolactin m'thupi lanu kuli kokwera chifukwa cha mankhwala omwe mukumwa, dokotala wanu adzakupatsani mankhwala ena omwe sadzakhudza kwambiri kuchuluka kwa prolactin m'thupi lanu.

Kodi mwayi wochira ndi wotani?

Hyperprolactinemia nthawi zambiri imachepa chifukwa choyambitsa matendawa chimachiritsidwa bwino.

Ngakhale izi sizikuika moyo pachiswe, zingayambitse mavuto monga kusabereka komanso kusayenda bwino kwa msambo, choncho ndikofunikira kwambiri kufunafuna chithandizo ngati muli ndi vutoli.

Mafunso oti mufunse dokotala wanu

Ngati muli ndi hyperprolactinemia, zingakhale zothandiza kufunsa dokotala wanu mafunso awa:

• N’chifukwa chiyani izi zinandichitikira ine?
• Ndi mayeso otani omwe ndiyenera kuchita?
• Kodi ndi njira ziti zochiritsira zomwe ndili nazo?
• Kodi ubwino ndi kuipa kwa njira iliyonse yochiritsira ndi kotani?
• Kodi vuto langa losabereka lidzathetsedwa nditatha chithandizochi?

Matenda a hyperprolactinemia angakhudze moyo wanu ndikusokoneza luso lanu lobereka ana. Koma chinthu chabwino kwambiri ndichakuti amatha kuchiritsidwa bwino. Ngati muli ndi zizindikiro za vutoli, onetsetsani kuti mwawonana ndi dokotala. Kenako kuyezetsa magazi kokha kungawone kuchuluka kwa prolactin m'magazi anu.

Pomaliza, zomwe muyenera kukumbukira

Mwaona, hyperprolactinemia ndi kuchuluka kwa mahomoni otchedwa prolactin m'thupi lathu. Izi zingayambitse mavuto monga kuvutika kutenga pakati, kuchepa kwa chilakolako chogonana, kusakhazikika kwa nthawi ya msambo mwa akazi, komanso kusabereka mwa amuna .

Choyambitsa chachikulu cha izi ndi chotupa chotchedwa ``Prolactinoma`` chomwe chimayamba mu pituitary gland. Vutoli likhozanso kuchitika chifukwa cha mankhwala ena ndi matenda ena .

Musadandaule! Pali mankhwala abwino ochizira izi. Ngati muli ndi zizindikiro izi, ndi bwino kupita kwa dokotala mwamsanga. Kenako mutha kupeza chomwe chikuyambitsa vutoli ndikuyamba chithandizo chomwe chikukuyenererani. Ndikofunikira kwambiri kusamalira thanzi lanu.

Prolactin , Hyperprolactinemia, Pituitary gland, Kusalingana kwa mahomoni, Kusabereka, Galactorrhea, Prolactinoma