Homoni yachinsinsi yomwe imalamulira kulemera: Zonse zokhudza Leptin

Kodi munayamba mwadzifunsapo kuti mumamva bwanji mukakhala okhuta? Tikadya, pakapita kanthawi timamva kuti "Chabwino, zakwana." N’chiyani chimapangitsa kuti munthu azimva choncho? Nanga n’chifukwa chiyani anthu ena samva okhuta mosasamala kanthu kuti adya motani? Leptin ndiye chinthu chofunikira kwambiri pa zonsezi. Iyi ndi homoni yomwe ndi yofunika kwambiri pakuwongolera thupi lathu. Tiyeni tikambirane mwachidule komanso molondola lero.

Kodi Leptin ndi chiyani, mwachidule?

Mwachidule, leptin ndi mahomoni opangidwa ndi maselo amafuta m'thupi lanu (mafuta). Amatchedwanso "hormone ya satiety." Ntchito yake yayikulu ndikutumiza uthenga ku ubongo wanu womwe umati, "Chabwino, mwakhala ndi mphamvu zokwanira, siyani kudya." Umu ndi momwe leptin imathandizira kusunga kulemera kwa thupi kokhazikika kwa nthawi yayitali.

Asayansi adapeza mahomoni a leptin mu 1994, zomwe zikutanthauza kuti pali kafukufuku wambiri womwe ukuchitika pa izi. Kugwirizana kwa Leptin sikuti kokha ndi kuchepetsa kulemera, komanso matenda monga matenda a Alzheimer's, thanzi la kubereka, ndi kusabereka kukufufuzidwa pakadali pano.

Mukamva mawu oti "kulamulira kulemera," mungaganize kuti, "O... kuti tithe kuwongolera leptin ndikuchepetsa thupi." Koma zoona zake n'zakuti, kulamulira homoni iyi momwe tikufunira sikophweka monga momwe timaganizira.

Kodi leptin imagwira ntchito bwanji m'thupi lathu?

Ntchito yaikulu ya Leptin ndikuthandizira kuti thupi lathu likhale lolemera. Izi zikutanthauza kuti, kupanga mgwirizano wa nthawi yayitali pakati pa kuchuluka kwa chakudya chomwe timadya ndi mphamvu zomwe thupi lathu limagwiritsa ntchito. Leptin imatiletsa kumva njala mosafunikira. Imathandiza kuti thupi lisasonyeze njala pamene silikufuna mphamvu (ma calories).

Leptin imagwira ntchito makamaka pokhudza gawo la ubongo wathu lotchedwa hypothalamus. Komabe, pali ma receptor m'zigawo zina za thupi omwe amayankha leptin.

Chofunika kwambiri n’chakuti, leptin siilamulira njala yathu kuyambira pa chakudya chimodzi kupita ku china. M’malo mwake, imagwira ntchito yoletsa kudya chakudya ndi kugwiritsa ntchito mphamvu kwa nthawi yayitali, zomwe zimapangitsa kuti thupi likhale lolimba.

Tangoganizirani kuti mukuyesera kuchepetsa thupi. Pamene mafuta m'thupi lanu akuchepa, kuchuluka kwa leptin m'thupi lanu kumachepanso. Izi zimatumiza chizindikiro ku ubongo wanu kuti muli ndi njala. Izi zimakupangitsani kumva njala kwambiri komanso kukhala ndi chilakolako. Izi zingapangitse kuti mudye kwambiri osazindikira. Ichi ndi chimodzi mwa zifukwa zomwe zimachititsa kuti kuchepetsa thupi kukhale kovuta.

Kodi kuchuluka kwa leptin kumayendetsedwa bwanji?

Leptin imapangidwa ndikutulutsidwa m'magazi ndi minofu yoyera yamafuta m'thupi lathu. Chifukwa chake, kuchuluka kwa leptin m'magazi anu kumagwirizana mwachindunji ndi kuchuluka kwa mafuta m'thupi lanu.

• Ngati muli ndi mafuta ochulukirapo m'thupi:Mlingo wa Leptin ndi wokwera kwambiri.
• Ngati mafuta m'thupi ndi ochepa: kuchuluka kwa leptin kumakhala kochepa.

Pakapita nthawi, ngati mafuta m'thupi lanu akuwonjezeka, kuchuluka kwa leptin kumawonjezeka, ndipo ngati mafuta m'thupi lanu akuchepa, kuchuluka kwa leptin kumachepa.

Kodi chimachitika ndi chiyani ngati kuchuluka kwa leptin kwakwera kwambiri? - Kukana kwa Leptin

Munthu wonenepa kwambiri amakhala ndi mafuta ambiri m'thupi mwake. Zotsatira zake, kuchuluka kwa leptin m'magazi mwake kumakhala kokwera kwambiri. Matendawa timawatcha hyperleptinemia .

Tsopano mwina mukuganiza kuti, "Ngati leptin ili yokwera, muyenera kumva kukhuta, ndiye muyenera kuwongolera kudya kwanu?" Koma zosiyana ndi zimenezi. Pamene kuchuluka kwa leptin m'thupi kwakwera kwa nthawi yayitali, ubongo umayamba kusalabadira chizindikiro cha leptin. Zili ngati munthu amene nthawi zonse amatifuulira ndipo timachita dzanzi patatha kanthawi. Izi zimatchedwa kukana leptin .

Kodi chimachitika n’chiyani chifukwa cha izi?

1. Kusakhuta: Ngakhale kuti muli ndi mafuta okwanira m'thupi lanu, ubongo wanu umaganiza kuti muli ndi njala. Choncho mukupitiriza kudya.

2. Thupi limalowa mu "njira ya njala": Chifukwa ubongo sulandira chizindikiro cha leptin, ubongo umaganiza kuti thupi lilibe mphamvu zokwanira ndipo tikusowa chakudya. Chifukwa chake, kuti tisunge mphamvu, mphamvu ya basal metabolic rate (BMR) ya thupi imachepa. Izi zikutanthauza kuti kuchuluka kwa ma calories omwe mumawotcha mukakhala chete kumachepa.

Mwanjira imeneyi, kukana kwa leptin, kumbali imodzi, kumawonjezera njala ndikuwonjezera kuchuluka kwa chakudya chomwe munthu amadya, ndipo kumbali ina, liwiro lomwe thupi limawotcha ma calories limachepa. Zinthu ziwirizi zikagwirizana, zotsatira zake zimakhala kunenepa kwambiri.

Zizindikirozi zitha kuchitika chifukwa cha zinthu zina, choncho ngati mukukumana ndi zizindikirozi, ndi bwino kulankhula ndi dokotala wanu.

Kodi chimachitika ndi chiyani ngati kuchuluka kwa leptin kumachepa?

Kusowa kwa Leptin ndi vuto losowa kwambiri . Nthawi zambiri limapezeka ndi vuto la majini lotchedwa congenital leptin deficiency . Munthu amene ali ndi vutoli amakhala ndi vuto lomwe maselo ake amafuta sangathe kupanga leptin.

Ngati leptin palibe, thupi limaganiza kuti palibe mafuta m'thupi. Izi zimawonetsa ubongo kuti uli ndi njala ndipo sungathe kulamulira. Zotsatira zake, ana aang'ono omwe ali ndi vutoli amakhala ndi chilakolako chosalamulirika chofuna kudya. Zotsatira zake, amakhala onenepa kwambiri (kunenepa kwa kalasi III) ali aang'ono kwambiri ndipo amachedwa kutha msinkhu.

Kodi kuchuluka kwa leptin m'magazi kungayesedwe?

Inde, kuyezetsa magazi kosavuta kumatha kuyeza kuchuluka kwa leptin. Komabe, iyi si mayeso omwe madokotala nthawi zambiri amalamula. Amangochitika pazochitika zapadera. Mwachitsanzo:

• Ngati mwana wamng'ono kwambiri ali ndi kunenepa kwambiri.
• Ngati munthu wonenepa kwambiri akupitirizabe kukhala ndi njala yosalamulirika.

Kawirikawiri, kuchuluka kwa leptin komwe kumakhala ndi thanzi labwino kumatha kukhala motere:

• Akazi: 0.5 - 15.2 ng/mL (nanograms pa mililita)
• Amuna: 0.5 - 12.5 ng/mL

Makhalidwe amenewa amatha kusiyana pang'ono kuchokera ku labu kupita ku labu, kotero ngati muli ndi kukayikira kulikonse pa makhalidwe omwe ali mu lipoti lanu, funsani dokotala wanu.

Kodi tingasinthe bwanji kuchuluka kwa leptin m'thupi?

Palibe njira yowonjezerera milingo ya leptin mwachinyengo kuti muchepetse njala, chifukwa milingo ya leptin imagwirizana mwachindunji ndi kuchuluka kwa mafuta m'thupi lanu.

Komabe, pali zinthu zingapo zomwe zingathandize pa ntchito ya leptin ndi mahomoni ena:

1. Gonani mokwanira: Kafukufuku wina adapeza kuti kusagona mokwanira kumawonjezera hormone ya njala ya ghrelin ndikuchepetsa hormone ya satiety leptin. Chifukwa chake, kugona mokwanira tsiku lililonse ndikofunikira kwambiri kuti mahomoni azikhala bwino.

2. Idyani zakudya zabwino: Kafukufuku wina akusonyeza kuti kuchuluka kwa triglycerides, mtundu wa mafuta m'magazi, kungasokoneze leptin kufika muubongo. Ngakhale kuti pali malingaliro osiyanasiyana pankhaniyi, nthawi zonse ndibwino kudya zakudya zoyenera zomwe zimaphatikizapo ndiwo zamasamba, zipatso, ulusi, mapuloteni abwino, ndi mafuta abwino, pamene mumachepetsa shuga, ufa, ndi zakudya zokonzedwa .

3. Kuchita masewera olimbitsa thupi nthawi zonse: Kafukufuku wasonyeza kuti kuchita masewera olimbitsa thupi kungathandize kuchepetsa kukana kwa leptin. Izi zikutanthauza kuti kuchita masewera olimbitsa thupi kungathandize kuti ubongo ukhale ndi mphamvu ya leptin.

Ngati mukuda nkhawa ndi kulemera kwanu, kapena mukufuna malangizo a momwe mungachepetsere thupi mwanjira yabwino, ndi bwino kulankhula ndi dokotala wanu. Ngati pakufunika kutero, angakutumizireni kwa dokotala wa matenda a endocrinologist.