Kodi munamvapo za Lynch Syndrome? Dzinali likhoza kukhala latsopano kwa inu. Koma ndi matenda a majini omwe amapatsiridwa kuchokera ku mibadwomibadwo omwe amawonjezera kwambiri chiopsezo chathu chokhala ndi khansa. Izi zimawonjezera chiopsezo chokhala ndi khansa, makamaka musanakwanitse zaka 50. Ndizachibadwa kumva mantha pang'ono mukamva mawu akuti "mukhoza kutenga khansa". Koma chofunika kwambiri ndikudziwa bwino za matenda otere. Chifukwa chake lero tikambirana izi mosavuta, m'njira yomwe mungamvetse.
Mwachidule, kodi Lynch Syndrome ndi chiyani?
Tangoganizani kuti thupi lathu lili ngati makina ovuta omwe amagwira ntchito motsatira buku lalikulu la malangizo (DNA). Majini athu ali ngati zilembo zomwe zili m'buku la malangizoli. Nthawi zina, pamakhala zolakwika m'buku la malangizoli, kapena 'zolakwika zolembera'. Mu zamankhwala, izi zimatchedwa kusintha kwa majini.
Matenda a Lynch ndi matenda omwe amayamba chifukwa cha kusintha kwa majini. Thupi lathu lili ndi mtundu wapadera wa majini omwe amazindikira ndikukonza zolakwika mu DNA yathu. Izi zimatchedwa jini ya ``kusalinganiza bwino (MMR)``. Zili ngati ''gulu lokonzanso'' m'thupi lathu. Munthu amene ali ndi matenda a Lynch ali ndi vuto mu jini imodzi mu ''gulu lokonzanso'' ili. Chifukwa chake, zolakwika mu DNA sizikonzedwa bwino. Maselo omwe ali ndi zolakwikazi amasonkhana ndipo pakapita nthawi, amakhala ndi mwayi waukulu wokhala ndi khansa.
Matendawa angakhudze aliyense. Chifukwa ndi matenda a majini. Nthawi zina mungatenge jini lolakwikali kuchokera kwa amayi kapena abambo anu. Nthawi zambiri, kusintha kwa majini kumeneku kungachitike m'thupi la munthu watsopano popanda aliyense m'banjamo. Mukayang'ana ziwerengero m'dziko ngati America, akuti pafupifupi munthu m'modzi pa anthu 279 ali ndi vutoli.
Kodi ndi zizindikiro ziti zomwe munthu amene ali ndi matenda a Lynch angakumane nazo?
Chofunika kudziwa apa ndichakuti matenda a Lynch alibe zizindikiro zinazake. M'malo mwake, ndi chizindikiro cha khansa zomwe zimayambitsidwa ndi matendawa. Chofala kwambiri mwa izi ndi khansa ya m'matumbo.
Kotero, nazi zizindikiro zodziwika bwino zomwe zingagwirizane ndi khansa ya m'matumbo:
| Chizindikiro | Kufotokozera |
|---|---|
| Magazi mu chopondapo | Chimbudzicho chingakhale chofiira kapena chakuda kwambiri chokhala ndi magazi osakanikirana. |
| Kupweteka m'mimba kapena nseru | Kupweteka m'mimba pafupipafupi kapena kusapeza bwino. |
| Kusintha kwa machitidwe a m'mimba | Kuyamba mwadzidzidzi kudzimbidwa kapena kutsegula m'mimba, kapena ndowe zopyapyala kuposa masiku onse. |
| Kutopa pafupipafupi | Kutopa nthawi zonse ngakhale mutapumula bwino. |
| Kutupa kapena kutupa | Kumva kukhuta kapena kudzimbidwa ngakhale mutadya pang'ono. |
| Kusanza kapena kusanza | Kusanza kapena kusanza popanda chifukwa chomveka bwino. |
Chofunika ndichakuti si aliyense amene amadwala matendawa. Nthawi zina khansa singasonyeze zizindikiro zilizonse mpaka itakula kwambiri. Chifukwa chake, ngati mukupitiriza kukhala ndi chimodzi mwa zizindikirozi, onetsetsani kuti mwaonana ndi dokotala wanu kuti akupatseni malangizo.
Ndi mitundu iti ya khansa yomwe ingayambike chifukwa cha vutoli?
Matenda a Lynch si matenda omwe amatsegula khomo la mtundu umodzi wa khansa. Amawonjezera chiopsezo chotenga khansa m'magawo osiyanasiyana a thupi. Ziwalo zomwe zili pachiwopsezo zimatha kusiyana kutengera jini yolakwika. `MLHL`, `MSH2`, `MSH6`, `PMS2` ndi `EPCAM` ndi majini asanu akuluakulu omwe akukhudzidwa.
Pansipa pali mitundu ina ya khansa yomwe Lynch syndrome imawonjezera chiopsezo cha matendawa.
| Mtundu wa khansa | Chiwalo cha thupi chogwirizana |
|---|---|
| Khansa ya m'matumbo ndi m'matumbo | Dongosolo la m'mimba |
| Khansa ya m'mimba/endometrial | Njira zoberekera za akazi |
| Khansa ya m'chiberekero | Njira zoberekera za akazi |
| Khansa ya m'mimba | Dongosolo la m'mimba |
| Khansa ya m'matumbo ang'onoang'ono | Dongosolo la m'mimba |
| Khansa ya kapamba | Dongosolo la m'mimba |
| Khansa ya mkodzo wapamwamba | Dongosolo la mkodzo |
| Khansa ya muubongo | Dongosolo la mitsempha |
| Khansa ya pakhungu | Khungu |
Khansa za m'matumbo zomwe zimayambitsa matenda a Lynch ndi zosiyana pang'ono. Zimakula mofulumira kwambiri kuposa khansa zomwe nthawi zambiri zimakula.Ngakhale zimatenga pafupifupi zaka 10 kuti kachilombo kakang'ono ka munthu wabwinobwino kakhale khansa, zimatenga chaka chimodzi kapena ziwiri zokha kwa munthu amene ali ndi matenda a Lynch.
Komanso, chifukwa cha vutoli, munthu amene adadwalapo khansa ya m'matumbo ndipo adachira ali pachiwopsezo chachikulu chodwalanso khansa yamtundu womwewo.
Taganizirani, pali chiopsezo cha khansa cha 15% chomwe chingayambirenso mkati mwa zaka 10 khansa yoyamba itachotsedwa opaleshoni. Chiwopsezochi chikhoza kukwera kufika pa 40% patatha zaka 20, ndipo kufika pa 60% patatha zaka 30. Izi zikusonyeza kufunika koyezetsa matenda nthawi zonse.
Kodi izi zimadutsa bwanji m'mibadwomibadwo?
Matenda a Lynch ndi matenda omwe amafalikira kuchokera ku mibadwomibadwo m'njira ya "autosomal dominant". Izi zikutanthauza kuti ngakhale kholo limodzi lokha, kaya mayi kapena bambo, ndi omwe ali ndi jini lolakwika, pali mwayi wa 50% kuti mwanayo adzalandira. Izi zikutanthauza kuti mwana aliyense ali ndi mwayi wa 50% wolandira ndi mwayi wa 50% wosalandira.
Choncho, ngati inu kapena wina m'banja mwanu mwapezeka ndi matenda a Lynch syndrome, ndikofunikira kwambiri kudziwitsa ena onse a m'banja mwanu. Makamaka abale anu, ana anu, ndi makolo anu ayenera kuuzidwa za chiopsezochi. Kuwatumiza kukayezetsa majini ndi uphungu kungapulumutse miyoyo yawo.
Ndingadziwe bwanji ngati ndili ndi vutoli? Ndi mayeso otani omwe ndiyenera kuchita?
Njira yabwino yotsimikizira ngati muli ndi matenda a Lynch ndikuchita mayeso a majini . Izi nthawi zambiri zimaphatikizapo kutenga magazi. Kapena kupopera mkamwa mwanu ndi swab. Kuyesaku kungathe kuzindikira molondola ngati muli ndi kusintha kwa majini komwe tidakambirana kale, monga MLHL ndi MSH2.
Ngati mwapezeka ndi matenda a Lynch syndrome, chinthu china chofunika kwambiri ndikupita kukayezetsa khansa nthawi zonse. Dokotala wanu adzakonza nthawi yoyezetsa khansa yomwe ili yoyenera kwa inu.
| Mayeso | Momwe mungachitire izi ndi nthawi yolangizira |
|---|---|
| Colonoscopy | Colonoscopy ndi njira yomwe chubu chopyapyala chokhala ndi kamera chimayikidwa kudzera mu anus kuti chione m'matumbo. Nthawi zambiri chimalimbikitsidwa chaka chilichonse kapena ziwiri . |
| Ultrasound ya Transvaginal | Kwa akazi, kuyezetsa m'chiuno, komwe kumaphatikizapo kulowetsa chipangizo chowunikira kudzera mu nyini ndikuwunika chiberekero ndi mazira, kumalimbikitsidwa chaka chilichonse kapena ziwiri . |
| Kusanthula mkodzo | Dziwani bwino za khansa yokhudzana ndi impso poyesa mkodzo. Ndikoyenera kuchita izi chaka chilichonse . |
| Endoscopy Yapamwamba | Chubu chokhala ndi kamera yoyikidwa kudzera pakamwa kuti ione mimba ndi matumbo ang'onoang'ono. Amalangizidwa zaka 3-5 zilizonse . |
| Kufufuza za thupi | Ngati minofu yokayikitsa kapena chotupa chapezeka panthawi yoyezetsa pamwambapa, chitsanzo chaching'ono chimatengedwa ndikuyesedwa maselo a khansa. |
Kodi matenda a Lynch amachiritsidwa bwanji?
Pakadali pano palibe mankhwala a matenda a Lynch syndrome. Chifukwa chake, cholinga chachikulu cha chithandizo ndikupeza ndikuchotsa maselo a khansa m'thupi mwa opaleshoni. Ngati khansayo ingapezeke ndikuchotsedwa isanafalikire ku ziwalo zina za thupi, zotsatira zake zimakhala zabwino kwambiri.
Izi zimafuna gulu la madokotala osiyanasiyana. Mwachitsanzo, madokotala a matenda a m'mimba, madokotala ochita opaleshoni, madokotala a khansa ya amayi, ndi madokotala a khansa amagwira ntchito limodzi pochiza vutoli.
Anthu ena, makamaka akazi omwe amaliza mabanja awo, amasankha kuchotsedwa chiberekero kapena kuchotsedwa mazira asanayambe matenda ena kuti achepetse chiopsezo chawo chokhala ndi khansa ya m'chiberekero kapena ya mazira mtsogolo. Mofananamo, omwe ali pachiwopsezo chachikulu cha khansa ya m'matumbo angasankhe kuchotsedwa chiberekero. Izi ndi zisankho zaumwini kwambiri, ndipo ziyenera kupangidwa mutakambirana zambiri ndi dokotala wanu.
Kodi matenda a Lynch ndi HNPCC ndi chinthu chimodzi?
Mwina munamvapo dzina lakuti `HNPCC (Heredary Non-Polyposis Colorectal Cancer)`. Lynch syndrome ndi HNPCC nthawi zambiri amagwiritsidwa ntchito mosiyana, koma pali kusiyana pang'ono kwaukadaulo pakati pa awiriwa.
Mwachidule, dzina lakuti HNPCC limagwiritsidwa ntchito potengera mbiri ya banja. Izi zikutanthauza kuti, ngati mamembala angapo a banja adadwala khansa yamtunduwu, banja limenelo limanenedwa kuti lili ndi HNPCC. Koma Lynch syndrome ndi dzina lomwe limaperekedwa pambuyo pa kusintha kwa majini komwe kumayambitsa kuti lizindikirike. Chifukwa chake, mamembala onse a banja omwe ali ndi HNPCC akhoza kukhala ndi kusintha kwa majini a Lynch syndrome. Komanso, munthu amene amapanga kusintha kwa majini atsopano popanda wina aliyense m'banjamo anganenenso kuti ali ndi Lynch syndrome.
Palibe amene amakonda kumva mawu akuti, "Muli ndi khansa." Munthu amene ali ndi matenda a Lynch syndrome angafunike kumva mawu amenewo nthawi ina m'moyo wake. Koma si mapeto a dziko. Ngati mukudziwa za vuto lanu, gwirani ntchito ndi dokotala wanu, ndipo nthawi zonse muziyezetsa khansa, khansa iliyonse imatha kuzindikirika ndikuchiritsidwa msanga. Kuzindikira msanga ndi chithandizo ndiyo njira yabwino kwambiri yokhalira ndi moyo wathanzi komanso wachimwemwe.
Uthenga Wopita Nawo Kunyumba
- Matenda a Lynch ndi matenda a majini omwe amafalikira kuchokera ku mibadwomibadwo ndipo amawonjezera chiopsezo cha khansa.
- Ngakhale kholo limodzi lokha litakhala ndi jini lolakwikali, mwana ali ndi mwayi wa 50% wolandira jiniyi.
- Ngati inu kapena munthu wina m'banja mwanu wapezeka ndi vutoli, ndikofunikira kwambiri kudziwitsa achibale ena za vutoli.
- Ngakhale kuti vutoli silingathe kuchiritsidwa, njira yabwino yopewera kapena kuzindikira khansa msanga ndikupita kukayezetsa nthawi zonse.
- Kuzindikira ndi kuchiza khansa msanga kungakuthandizeni kukhala ndi moyo wathanzi.
- Nthawi zonse funsani dokotala wanu kuti akonze nthawi yoyezetsa yomwe ikugwirizana ndi inu komanso kuthetsa mavuto aliwonse.
💬 Comments (0)
Palibe ndemanga zomwe zatumizidwa pano. Onjezani ndemanga yanu pano koyamba.
Onjezani ndemanga yanu