Kodi maselo a mast awa ndi chiyani? Kodi ichi ndi chomwe chimayambitsa ziwengo zanu?

Kodi mumayambanso kuyetsemula mukakhudza fumbi? Kapena mukalumidwa ndi nyerere kapena udzudzu, malowo amakhala ofiira, otupa, komanso oyabwa kwambiri? Ambiri a ife takumanapo ndi zofanana. Chifukwa chake, lero tikambirana za munthu wofunikira kwambiri amene amachititsa izi zomwe zimachitika m'thupi lathu nthawi zina ngati izi. Ameneyo ndi "Mast Cells ".

Mwachidule, kodi maselo a mast awa ndi ndani?

Maselo a m'mimba ndi asilikali apadera mu chitetezo chanu chamthupi. Monga momwe dziko lathu lilili ndi gulu lankhondo loteteza, thupi lathu lilinso ndi chitetezo chamthupi choteteza. Maselo a m'mimba awa ndi alonda mu dongosolo limenelo, nthawi zonse amakhala maso.

Maselo amenewa amapangidwa m'mafupa athu. Kenako amayenda m'magazi ndikukhazikika m'maselo osiyanasiyana a thupi lathu. Apa ndi pomwe ntchito yawo imayambira. Ntchito yawo yayikulu ndi kutiteteza ku zoopsa zosiyanasiyana zomwe zingachitike mthupi.

Koma nthawi zina maselo a mast awa amakhala otanganidwa kwambiri. Apa ndi pomwe mavuto amayamba. Angayambitse vuto lalikulu ngakhale ku zinthu zopanda vuto monga fumbi kapena chakudya. Matendawa timawatcha kuti 'allergies' kapena 'allergic asthma'. Nthawi zina zoopsa, ntchito ya maselo a mast awa ingayambitse vuto lalikulu lotchedwa anaphylaxis, lomwe lingakhale pachiwopsezo cha moyo.

Kodi mast cell awa amagwira ntchito bwanji? Tiyeni timvetse 'dongosolo la alamu' ili!

Ganizirani thupi lanu ngati linga lalikulu. Ma cell a mast ali ngati makina ochenjeza omwe amaikidwa paliponse pamakoma a linga limenelo. Makina ochenjeza awa nthawi zonse amakhala okonzeka kuteteza thupi ku adani akunja, kutanthauza, tizilombo toyambitsa matenda monga mavairasi ndi mabakiteriya, ndi poizoni monga poizoni wa njoka ndi poizoni wa mavu.

Tiyeni tiwone momwe njirayi imachitikira mwatsatanetsatane:

1. Kuzindikira mdani: Choyamba, kachilombo katsopano kakalowa m'thupi lanu, gawo la chitetezo chamthupi chotchedwa B-cells limazindikira.

2. Kupanga zida zapadera: Pambuyo pozindikira mdani, maselo a B amayamba kupanga mtundu wa antibody womwe ndi wapadera kwa mdaniyo. Ma antibodies amenewa amatchedwa immunoglobulin E (IgE) .

3. Kupatsa alonda zida:Ma antibodies opangidwa ndi IgE amenewa amapita pamwamba pa maselo a mast, omwe ndi ngwazi za m'nkhani yathu. Zili ngati kupatsa mlonda chida.

4. Alamu ikulira: Tsopano maselo a mast ali ndi IgE. Nthawi ina mdani yemweyo (monga kachilombo komweko kapena allergen) akalowanso m'thupi, IgE imagwidwa ndi maselo a mast. Pamenepo ndi pamene maselo a mast ``amayatsidwa''.

5. Kuukira kwa histamine: Maselo a mast cell akayamba kugwira ntchito, amatulutsa mankhwala ambiri omwe amasungidwa mkati mwawo nthawi imodzi. Mankhwala ofunikira kwambiri ndi histamine .

Tiyeni tione zina mwa zinthu zomwe zimachitika m'thupi lathu pamene mankhwala otchedwa histamine atulutsidwa.

Tsopano mukumvetsa zomwe zimachitika m'thupi lathu tikakhala ndi vuto la ziwengo, sichoncho? Ngakhale zonsezi zimachitika kuti zititeteze, nthawi zina yankholi limakhala loopsa kwambiri.

Kodi maselo a mast awa ndi otani m'thupi?

Alonda amenewa nthawi zambiri amakhala pakhomo lalikulu lomwe majeremusi ndi zinthu zina zomwe zimayambitsa matenda akunja zimalowera.

• Mapapu ndi njira zopumira: Dzitetezeni ku zinthu zomwe zimabwera ndi mpweya umene timapuma.
• M'mimba (GI tract): Dzitetezeni ku majeremusi omwe amabwera ndi zinthu zomwe timadya ndi kumwa.
• Khungu: Dzitetezeni ku zinthu zomwe zimalowa pamwamba pa khungu.
• Maselo amenewa amapezekanso mozungulira mitsempha yamagazi ndi mitsempha .

Kodi ndi matenda ati omwe angayambitse matenda okhudzana ndi maselo a mast?

Maselo a mast akalephera kugwira ntchito bwino, matenda osiyanasiyana amatha kuchitika. Ena mwa iwo ndi ofala komanso odziwika bwino.

Dziwani zizindikiro izi.

Zizindikiro za matenda a mast cell zingaphatikizepo:

• Kufiira kwa khungu, kuyabwa, kumva kutentha.
• Kutupa (edema) m'mbali zosiyanasiyana za thupi.
• Kuvuta kupuma.
• Matenda oopsa kwambiri (anaphylaxis).

Ngati mumakhala ndi zizindikiro zimenezi pafupipafupi, ndikofunikira kwambiri kuonana ndi dokotala kuti akupatseni upangiri m'malo modzipatsa mankhwala.

Kodi dokotala amazindikira bwanji matenda amenewa? Kodi mankhwala ake ndi otani?

Ngati dokotala wanu akukayikira kuti muli ndi matenda a mast cell kutengera zizindikiro zanu, akhoza kuyitanitsa mayeso osiyanasiyana.

• Kuyezetsa magazi
• Mayeso a mkodzo
• Kuyesa khungu la ziwengo
• Nthawi zina chitsanzo chaching'ono cha mafuta a m'mafupa kapena khungu chimatengedwa kuti chikayesedwe ('biopsy').

Njira zochiritsira zimasiyana malinga ndi wodwala aliyense komanso kutengera mtundu wa vutolo. Mankhwala ofala kwambiri angaphatikizepo:

• Kupewa zinthu zomwe zimayambitsa ziwengo: Kudziwa zomwe zimayambitsa ziwengo ndi kuzipewa.
• Mankhwala: Mankhwala operekedwa kuti achepetse zizindikiro. Zitsanzo zake ndi monga mankhwala oletsa kutupa ndi montelukast.
• Mankhwala okhazikika a mast cell: Mankhwalawa amagwira ntchito poletsa kutulutsa mankhwala monga histamine kuchokera ku mast cell.
• Mankhwala adzidzidzi: Mankhwala monga epinephrine a anaphylaxis yoopsa.

Pomaliza, kodi maselo a mast ndi abwino kapena oipa?

Anthu ambiri amangomva za mast cells akakhala ndi vuto lovuta monga allergy, kotero angaganize kuti ndi chinthu choipa. Koma zoona zake, mast cells ndi gawo lofunikira komanso lofunika kwambiri pa chitetezo cha thupi lathu.

Nthawi zambiri, amatiteteza ku matenda ndi majeremusi. Ndi pamene ayamba kusangalala kwambiri ndipo timakumana ndi mavuto a ziwengo. Monga gulu la alonda achangu kwambiri omwe amayatsa mudzi wonse kuti agwire wakuba wamng'ono.

Kotero, nthawi ina mukadzayetsemula kapena kudzikanda, thokozani kwambiri ma cell ang'onoang'ono awa. Chifukwa amagwira ntchito molimbika kuti akutetezeni!