Nchifukwa chiyani matenda a chiwindi otchedwa PBC amapezeka kwambiri mwa akazi? (Primary Biliary Cholangitis - PBC)

Kodi mudamvapo za matenda a chiwindi otchedwa PBC? Mwina simukudziwa dzina lake. Koma kodi mumadziwa kuti anthu asanu ndi anayi mwa khumi aliwonse omwe akudwala matendawa ndi akazi? N'zosadabwitsa, sichoncho? Ndiye n'chifukwa chiyani matendawa akuoneka kuti akuyang'ana akazi? Chifukwa chake ndi chiyani? Lero, tikambirana za izi mosavuta, m'njira yomwe mungamvetse.

Choyamba tiyeni tiwone, kodi PBC ndi chiyani?

Chabwino, ili ndi dzina la sayansi, koma zomwe zimachitika n'zosavuta. PBC, yomwe imayimira Primary Biliary Cholangitis, ndi matenda omwe chitetezo cha mthupi lathu chimataya mphamvu zake ndikuukira chiwindi chathu. Matenda oterewa timawatcha matenda odziteteza. Taganizirani izi, chitetezo cha mthupi lathu chili ngati gulu lankhondo lomwe limateteza dziko. Ntchito ya gulu lankhondo ili ndikulimbana ndi majeremusi ndi mavairasi omwe amachokera kunja ndikutipulumutsa ku matenda. Koma nthawi zina gulu lankhondo ili limalakwitsa ndikuyamba kuukira anthu osalakwa m'dziko lake. Chinthu chofanana ndi ichi chimachitika mu PBC. Chitetezo chathu cha mthupi chimaukira ducts zazing'ono za ndulu m'chiwindi chathu. ducts izi ndi njira yofunika kwambiri ya machubu omwe amanyamula ndulu yopangidwa ndi chiwindi kupita kumatumbo. Pamene ducts izi zawonongeka, ndulu simayenda bwino ndipo imasonkhana mkati mwa chiwindi, pang'onopang'ono kuwononga chiwindi.

Nanga n’chifukwa chiyani izi zimakhudza akazi kwambiri?

Tsopano tiyeni tiwone yankho la funso lalikulu lomwe aliyense ali nalo. Ofufuza sanapezebe chifukwa chimodzi chomveka bwino cha izi. Komabe, amakhulupirira kuti pali zinthu zitatu zazikulu zomwe zimapangitsa kuti izi zichitike.

1. Mphamvu ya mahomoni

Mukudziwa, matupi a akazi ndi osiyana kwambiri ndi matupi a amuna. Chifukwa chachikulu cha zimenezi ndi mahomoni. Makamaka, mahomoni otchedwa estrogen amachita gawo lofunika kwambiri pa gawo lililonse la moyo wa mkazi. Taganizirani izi, ndi nthawi ya msambo pamwezi, makamaka ndi nthawi ya kusamba, yomwe imachitika pakati pa zaka 40-60, pali kusintha kwakukulu pa kuchuluka kwa mahomoni a estrogen awa. Kusintha kwa mahomoni kumeneku kumakhudza mwachindunji momwe maselo a chitetezo chathu chamthupi amagwirira ntchito. Homoni ya estrogen imatha kulimbikitsa chitetezo chamthupi kwambiri. Ndiko kuti, kuyambitsa "gulu" lomwe tidalankhula kale kwambiri. Izi zikachitika, chiopsezo choukira maselo ake chimawonjezeka. Titha kuganiza za kulumikizana kumeneku popeza PBC ndi yofala kwambiri pakati pa akazi azaka izi.

2. Mabakiteriya m'matumbo

Izi zitha kukhala zatsopano kwa inu. Mabakiteriya ambiri abwino ndi oipa amakhala m'matumbo mwathu. Gulu la mabakiteriyali ndi lofunika kwambiri pa thanzi lathu. Kafukufuku wapeza kuti anthu omwe ali ndi chibadwa choyambitsa matenda a PBC amakhala ndi mitundu yosiyanasiyana ya mabakiteriya m'matumbo mwawo kuposa ena. Alinso ndi mitundu yambiri ya mabakiteriya omwe nthawi zambiri amagwirizanitsidwa ndi matenda a mkodzo (UTIs). Izi zikusonyeza kuti matenda ena a mabakiteriya komanso kusalingana kwa mabakiteriya m'matumbo kungakhale kothandiza pakukula kwa matenda a PBC posokoneza chitetezo cha mthupi.

3. Mphamvu ya majini ndi cholowa

"Kodi uwu ndi matenda obadwa nawo?" mwina mukudzifunsa. Inde, mpaka pamlingo wina, majini amachitapo kanthu.

• Pakati pa 1% ndi 9% ya anthu omwe ali ndi PBC ali ndi wachibale wina amene ali ndi matendawa.
• Ngati m'modzi mwa mapasa awiri ofanana ayamba kukhala ndi PBC, pali mwayi wa 63% kuti winayonso adzayamba kukhala ndi PBC.

Chofunika kwambiri kuposa zonsezi ndi momwe chromosome ya X imagwirira ntchito. Mwachidule, akazi ali ndi ma chromosome awiri a X (XX), pomwe amuna ali ndi chromosome imodzi ya X ndi chromosome imodzi ya Y (XY). Kafukufuku wasonyeza kuti akazi omwe ali ndi PBC ali ndi chromosome imodzi ya X yomwe ikusowa kapena ali ndi kusintha kwina mu chromosome ya X m'maselo ena a matupi awo. Kusintha kumeneku kungakhudze momwe majini omwe ali m'thupi amagwirira ntchito, zomwe zimawonjezera chiopsezo chotenga matendawa.

Kodi n'zotheka kukhala bwino ndi PBC?

Inde ndithu! PBC ndi matenda omwe angathe kulamulidwa bwino ndi chithandizo choyenera chamankhwala komanso kusintha moyo. Matendawa akapezeka msanga, zimakhala zosavuta kuwongolera kuwonongeka kwa chiwindi. Chofunika kwambiri mukakhala ndi matendawa ndikukhalabe ndi ubale wokhazikika ndi dokotala wanu . Ndikofunikira kumwa mankhwala omwe amakulemberani panthawi yake, kupita kuzipatala nthawi yake. Kuphatikiza apo, mwa kudya zakudya zoyenera, kupewa kumwa mowa kotheratu, komanso kuchita masewera olimbitsa thupi oyenera monga momwe dokotala wanu walangizira, mutha kukhala ndi moyo wathanzi. Tsopano pali mankhwala abwino kwambiri oletsa zizindikiro za matendawa, monga kutopa kwambiri ndi khungu loyabwa. Chifukwa chake lankhulani momasuka ndi dokotala wanu za izi. PBC, Cholangitis Yoyamba ya Biliary, Matenda a Chiwindi, Thanzi la Akazi, Matenda a Autoimmune, Estrogen, Mahomoni, Majini, Matenda a Chiwindi mwa Akazi Sinhala, akmawe leda