Kodi Rabson-Mendenhall Syndrome ndi chiyani? Tiyeni tikambirane za vuto losowa ili.

Chinthu chofunikira kwambiri chomwe chimachitika m'thupi lathu ndichakuti chakudya chomwe timadya chimatipatsa mphamvu. Zili ngati kuyika mpweya m'galimoto. Apa, thupi lathu limapeza mphamvu kuchokera ku shuga (shuga). Njira yonseyi imayendetsedwa ndi mahomoni otchedwa insulin . Ndi insulin iyi yomwe imauza shuga m'magazi kuti itumizidwe m'maselo omwe amafunikira mphamvu. Zili ngati kutsegula zitseko za maselo ndikulola shuga kulowa. Komabe, m'thupi la munthu yemwe ali ndi Rabson-Mendenhall Syndrome, njirayi sichitika bwino. Izi zikutanthauza kuti, thupi lawo silingagwiritse ntchito insulin moyenera. Iyi ndi vuto losowa kwambiri.

Ndiye kodi matenda amenewa ndi otani kwenikweni?

Pamene insulin singagwire ntchito yake bwino, imakhudza mwachindunji kukula kwa mwana. Tangoganizirani, zotsatira zake zimayamba ngakhale mwana asanabadwe, kutanthauza kuti, ali m'mimba mwa mayi ake. Makanda omwe ali ndi vutoli nthawi zambiri amakhala ang'onoang'ono. Ngakhale atabadwa, kulemera kwawo ndi kukula kwa thupi kumachitika pang'onopang'ono kwambiri. Ponena za zamankhwala, Rabson-Mendenhall syndrome ndi matenda omwe ali m'gulu lalikulu lotchedwa severe insulin resistance syndromes. Donohue syndrome ndi type A insulin resistance syndrome ndi matenda ena awiri omwe ali m'gululi.

Kodi chifukwa cha vutoli n'chiyani?

Mwachidule, iyi ndi matenda a majini. Ndiye kuti, amatengera kwa makolo kupita kwa mwana . Izi zimachitika chifukwa cha vuto la jini lotchedwa `INSR` m'thupi mwathu. Tsopano tiyeni tiwone momwe izi zimachitikira. Mu selo lililonse la thupi lathu, muli makope awiri a jini iliyonse. Limodzi lochokera kwa amayi, ndi lina lochokera kwa abambo. Kuti mwana akhale ndi matenda a Rabson-Mendenhall, makope onse a jini la `INSR` lomwe mwana amalandira ayenera kukhala ndi vuto lomwe lanenedwa. Ngati kopi imodzi yokha ili ndi vuto, matendawa sadzakula. Mwanjira ina, kuti mwana akhale ndi matendawa, mayi ndi bambo ayenera kukhala ndi kopi imodzi ya jini lolakwika ili ndi kopi imodzi ya jini lathanzi. Kenako, mwanayo ayenera kulandira makope onse awiri olakwika kuchokera kwa onse mwangozi. Ichi ndichifukwa chake zimakhala zachilendo chifukwa nthawi zambiri sizimachitika katatu kapena kanayi.

Kodi zizindikiro za vutoli ndi ziti?

Zizindikiro nthawi zambiri zimayamba kuonekera mkati mwa chaka choyamba cha moyo wa mwana. Komanso, kuopsa kwa zizindikirozi kumatha kusiyana malinga ndi munthu. Tiyeni tiwone zizindikiro zazikulu zomwe zingawonekere.

Matenda ena omwe angachitike chifukwa cha izi

Kuwonjezera pa zizindikiro zoyambira izi, matendawa angayambitsenso matenda ena akuluakulu.

• Matenda a m'mimba mwa atsikana.
• Matenda a shuga . Izi nthawi zina zingayambitse matenda oopsa otchedwa ketoacidosis .
• Mavuto a impso .

Kodi matenda amachitika bwanji?

Chimodzi mwa zovuta pozindikira vutoli ndi kusiyanitsa ndi matenda ena omwe amaoneka ofanana (monga Donahue syndrome). Dokotala wa mwana wanu adzamufufuza bwino thupi, kumufunsa za zizindikiro za mwana wanu komanso mbiri ya thanzi la banja lake, ndipo mwina adzalamula kuti ayese magazi angapo kuti awone kuchuluka kwa shuga m'magazi a mwana wanu ndi insulin . Iyi ndiyo njira yokhayo yodziwira matenda molondola.

Kodi chimachiritsidwa bwanji?

Chithandizo cha matenda a Rabson-Mendenhall nthawi zambiri chimafuna thandizo la gulu lalikulu, kuphatikizapo akatswiri osiyanasiyana, madokotala ochita opaleshoni, ndi madokotala a mano. Uphungu ungakhalenso wofunikira kwambiri kwa mabanja kuti athe kuthana ndi nkhawa ndi malingaliro omwe amabwera chifukwa chokhala ndi mwana yemwe ali ndi vutoli losowa. Chithandizo nthawi zambiri chimakhala chapadera pa chizindikiro chilichonse. Mwachitsanzo, opaleshoni yochotsa ma cysts a ovarian, chithandizo cha mano pamavuto a mano, ndi zina zotero. Nthawi zina, madokotala amapereka mlingo waukulu wa insulin kapena mankhwala ena omwe amalimbikitsa kugwiritsa ntchito insulin, koma nthawi zambiri izi sizigwira ntchito kwa nthawi yayitali.

Mankhwala atsopano akufufuzidwa

Akatswiri akupitiliza kufufuza njira zabwino zochizira matenda a shuga wambiri m'magazi (hyperglycemia) omwe amabwera chifukwa cha kukana kwambiri insulin. Ngakhale kuti mankhwala awa awonetsa zotsatira zabwino, kafukufuku wowonjezereka akufunika.

• Biguanides: Awa ndi mtundu wa mankhwala omwe amachepetsa kupanga shuga m'thupi ndikuwonjezera kugwiritsa ntchito insulin .
• Leptin: Puloteni iyi yapezeka kuti imathandiza kuwongolera shuga m'magazi ndi kuchuluka kwa insulin.
• rhIGF-I (Recombinant insulin-like growth factor I): Puloteni iyi imagwiritsidwa ntchito pochiza ketoacidosis, matenda omwe amayamba chifukwa cha kukana kwambiri insulin .

Matenda a Rabson-Mendenhall, kukana insulini, matenda a majini, matenda a ana, acanthosis nigricans, ketoacidosis, matenda a shuga