Kuyamba chithandizo cha khansa kwa inu kapena wokondedwa wanu kungakhale nthawi yovuta komanso yosokoneza. Mungakhale ndi mafunso okhudza mankhwala omwe dokotala wanu akukupatsani, mayina awo, ndi zotsatira zake. Lero tikambirana za mankhwala apadera a khansa, Selpercatinib . Mutha kuwadziwa ndi dzina loti Retevmo. Tiyeni tikambirane za mankhwalawa, zomwe amachita, komanso zomwe muyenera kudziwa m'njira yosavuta kumva.
Kodi kwenikweni chimachitika ndi mankhwala awa ndi chiyani?
Mwachidule, Selpercatinib si ngati mankhwala achikhalidwe a chemotherapy. Imagwira ntchito ngati "mankhwala olunjika." Mapuloteni ena m'thupi lathu amatumiza zizindikiro ku maselo a khansa kuti "akule kwambiri, afalikire mwachangu." Taganizirani izi ngati switch yomwe imapangitsa maselo a khansa kukula. Zimene Selpercatinib imachita ndikutseka puloteni yomwe imatumiza chizindikiro cholakwika . Zili ngati kuzimitsa switch imeneyo. Kenako kukula ndi kufalikira kwa maselo a khansa m'thupi lonse kumalamulidwa.
Zinthu zomwe muyenera kuuza dokotala wanu musanayambe kumwa mankhwala
Musanayambe chithandizochi, dokotala wanu ayenera kudziwa bwino thanzi lanu. Onetsetsani kuti mwawauza za vuto lililonse mwa zotsatirazi, makamaka ngati muli nalo:
| Kodi muli ndi vutoli? | N’chifukwa chiyani chidziwitso chili chofunika? |
|---|---|
| Matenda otuluka magazi | Mankhwalawa angawonjezere chiopsezo cha kutuluka magazi. |
| Wangochitidwa opaleshoni posachedwapa kapena wakonzekera kuchitidwa opaleshoni mtsogolo | Mankhwalawa angachedwetse kuchira kwa bala. |
| Kuthamanga kwa magazi | Mankhwalawa amatha kuonjezera kuthamanga kwa magazi. |
| Kugunda kwa mtima kosakhazikika | Kusintha kwa kugunda kwa mtima kungachitike. |
| Matenda a chiwindi kapena mapapo | Ntchito ya ziwalo izi ingakhudzidwe. |
| Matenda a chifuwa cha mankhwala ena, zakudya, kapena utoto | Ndikofunikira kudziwa ngati muli ndi vuto la ziwengo ndi mankhwala kapena chilichonse mwa zosakaniza zake. |
| Kukhala ndi pakati kapena kuyesa kutenga mimba | Mankhwalawa akhoza kuvulaza kwambiri mwana wosabadwa. |
| Kuyamwitsa | Mankhwalawa amatha kuperekedwa kwa mwana kudzera mu mkaka wa m'mawere. |
Kodi ndiyenera kugwiritsa ntchito bwanji mankhwalawa?
Iyi ndi kapisozi yomwe mumamwa. Ndikofunikira kwambiri kumwa nthawi yomweyo tsiku lililonse , monga momwe dokotala wanu wanenera.
- Mezani kapisozi yonse ndi madzi . Musaswe, kuphwanya, kapena kutafuna kapisoziyo.
- Mungathe kumwa izi muli ndi chakudya kapena ayi. Komabe, ngati mukumva kupweteka m'mimba pang'ono, ndi bwino kumwa izi muli ndi chakudya.
- Pitirizani kulandira chithandizo mpaka dokotala atakuuzani kuti musiye.
- Chofunika kwambiri: Pewani kumwa madzi a mphesa kotheratu mukamamwa mankhwalawa.
Nanga bwanji ngati ndaphonya mlingo wa mankhwala?
Ngati mwaphonya mlingo, imwani mwamsanga mukangokumbukira. Komabe, ngati papita maola opitilira 18 kuchokera pa mlingo wanu wotsatira (kutanthauza kuti pali maola ochepera 6 mpaka mlingo wanu wotsatira), dumphani mlingo womwe mwaphonya ndikumwa mlingo wanu wotsatira panthawi yokhazikika. Musamwe milingo iwiri nthawi imodzi kuti mubwezeretse mlingo womwe mwaphonya.
Nanga bwanji ngati nditamwa mankhwala ochulukirapo?
Ngati mukuganiza kuti mwamwa mankhwala ambiri kuposa momwe mukuganizira, musachite mantha. Pitani ku Dipatimenti Yoona za Zadzidzidzi (ETU) yapafupi nthawi yomweyo. Kapena, imbani National Poisons Information Centre ku Colombo National Hospital kuti mupeze malangizo.
Zinthu zina zomwe zingagwirizane ndi mankhwalawa
Mankhwala ena amatha kusokonezana ndi Selpercatinib, kusintha mphamvu yake kapena kuwonjezera zotsatira zake zoyipa.
Chenjezo: Ngati mukumwa mankhwala aliwonse mwa awa, musamwe Selpercatinib. Lankhulani ndi dokotala wanu za izi.
* Cisapride
* Dronedarone
* Ketoconazole
* Levoketoconazole
* Pimozide
* Thioridazine
Kuphatikiza apo, mankhwala ena, mankhwala ochokera ku zitsamba, ndi zakudya zingagwirizane ndi mankhwalawa. Chifukwa chake, ndikofunikira kuuza dokotala wanu za mankhwala onse omwe mukumwa (kuphatikizapo mavitamini, mankhwala ochokera ku zitsamba, ndi zowonjezera).
- Mankhwala ena othamanga magazi (diltiazem kapena verapamil)
- Mankhwala ena oletsa mavairasi a HIV kapena Hepatitis
- Mankhwala ochizira matenda a bowa (itraconazole, posaconazole)
- Madzi a mphesa
- Mankhwala ena omwe amasintha kugunda kwa mtima
- Repaglinide ya matenda ashuga
- Rifampin yochizira chifuwa chachikulu
- Zinthu zochokera ku zitsamba monga St. John's Wort
- Mankhwala ochepetsa asidi m'mimba (monga cimetidine, famotidine, ranitidine, lansoprazole, omeprazole)
Zinthu zofunika kusamala kwambiri mukamamwa mankhwala
- Kumva kudwala: Ndizachibadwa kumva kudwala pang'ono kapena kudwala mukamagwiritsa ntchito mankhwalawa. Izi zili choncho chifukwa mankhwalawa amakhudza maselo a khansa komanso maselo athanzi pamlingo winawake. Komabe, musasiye kulandira chithandizo mpaka dokotala wanu atakuuzani. Uzani dokotala wanu za zotsatirapo zilizonse zomwe mumakumana nazo.
- Opaleshoni: Ngati mukufuna kuchitidwa opaleshoni (ngakhale itakhala yaying'ono monga kuchotsa dzino), uzani dokotala wanu. Mankhwalawa angachedwetse kuchira kwa bala. Chifukwa chake, nthawi zambiri muyenera kusiya kumwa mankhwalawa masiku osachepera 7 opaleshoni isanachitike ndikuyambanso milungu iwiri pambuyo pa opaleshoni, bala litachira kwathunthu.
- Mimba ndi kuyamwitsa: Kwa akazi: Pewani kutenga mimba mukumwa mankhwalawa komanso kwa sabata imodzi mutasiya kumwa mankhwalawa. Ichi ndichifukwa chake ndikofunikira kugwiritsa ntchito njira yodalirika yolerera. Muyenera kuyesa mimba musanayambe kumwa mankhwalawa kuti muwonetsetse kuti simuli ndi pakati. Komanso, pewani kuyamwitsa panthawiyi komanso kwa sabata imodzi mutasiya kumwa mankhwalawa. Kwa amuna: Nthawi zonse gwiritsani ntchito kondomu ngati mukugonana ndi mkazi amene angatenge mimba mukumwa mankhwalawa komanso kwa sabata imodzi mutasiya kumwa mankhwalawa. Ngati mnzanu atenga mimba, zingakhale zoopsa kwa mwana m'mimba.
- Kubereka: Mankhwalawa angakhudze kuthekera kwanu kubereka ana. Lankhulani ndi dokotala wanu ngati muli ndi nkhawa iliyonse pankhaniyi.
- Kuthamanga kwa magazi:Nthawi zonse muziyang'ana kuthamanga kwa magazi anu monga momwe dokotala wanu wanenera. Dziwani zomwe ziyenera kukhala komanso nthawi yomwe muyenera kuyimbira dokotala wanu.
Kodi ndi zotsatirapo zotani zomwe ndingakumane nazo?
Monga mankhwala ena aliwonse, Selpercatinib ingayambitse zotsatirapo zina. Zina zimakhala zoopsa, pomwe zina zimakhala zofala.
| Zotsatira zoyipa | Kufotokozera |
|---|---|
| Zotsatirapo zoyipa zomwe ziyenera kufotokozedwa kwa dokotala wanu nthawi yomweyo | |
| Matenda a ziwengo | Kutupa pakhungu, kuyabwa, kutupa kwa nkhope, milomo, lilime kapena pakhosi. |
| Kutuluka magazi kosazolowereka | Ndowe zakuda kapena zamagazi, kusanza magazi omwe amaoneka ngati khofi wophikidwa, mkodzo wakuda/wofiira, madontho ofiira/ofiirira pakhungu. |
| Kuvuta kupuma | Chifuwa chouma, kupuma movutikira. |
| Kusintha kwa kugunda kwa mtima | Kugunda kwa mtima, chizungulire, kupweteka pachifuwa. |
| Kuvulala kwa chiwindi | Kupweteka kumtunda kwa kumanja kwa m'mimba, kusowa chilakolako cha chakudya, khungu kapena maso kukhala achikasu, ndowe zowala, mkodzo wakuda wachikasu/bulauni. |
| Hypothyroidism | Kutopa kosazolowereka, kulephera kupirira chimfine, kudzimbidwa, kutaya tsitsi, khungu louma, komanso kunenepa. |
| Matenda a Tumor Lysis (TLS) | Kusanza, kutsegula m'mimba, kuchepa kwa kukodza, kugwedezeka kwa minofu, kupweteka kwa mafupa, kusokonezeka maganizo. |
| Uzani dokotala wanu ngati zikupitirira kapena zikukuvutitsani. | |
| Kudzimbidwa, kutsegula m'mimba, pakamwa pouma, nseru, ziphuphu pakhungu, kutupa kwa akakolo, mapazi, ndi manja. | |
Mndandandawu sukuphatikizapo zotsatirapo zonse zomwe zingachitike. Ngati mukukumana ndi vuto lililonse lachilendo, lankhulani ndi dokotala wanu za vutoli.
Uthenga Wopita Nawo Kunyumba
- Selpercatinib ndi mankhwala omwe amalimbana ndikuletsa puloteni inayake yomwe imakhudza kukula kwa maselo a khansa.
- Imwani mankhwala nthawi yomweyo tsiku lililonse monga momwe dokotala wanu wanenera. Musamwe ndi madzi a mphesa.
- Uzani dokotala wanu za mankhwala ena onse (kuphatikizapo mavitamini ndi mankhwala azitsamba) omwe mukumwa.
- Mankhwalawa si oyenera ngati muli ndi pakati, mukufuna kutenga pakati, kapena mukuyamwitsa. Ndikofunikira kuti akazi ndi amuna agwiritse ntchito njira zolerera zoyenera panthawi ya chithandizo komanso kwa sabata imodzi pambuyo pake.
- Ngati mukukumana ndi mavuto ena aakulu monga kupuma movutikira, kutuluka magazi ambiri, kapena zizindikiro zoopsa za ziwengo, funsani upangiri wa dokotala nthawi yomweyo.
- Musaope kulankhula ndi dokotala wanu za mafunso kapena nkhawa zilizonse zomwe mungakhale nazo. Kumbukirani kuti simuli nokha.
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