Kodi mukudziwa za mankhwala omwe amaletsa maselo a khansa 'kudya'? (Angiogenesis Inhibitors)

Ngakhale tikamva mawu akuti khansa, tonsefe timachita mantha kwambiri. Koma lerolino, sayansi ya zamankhwala yapita patsogolo kwambiri. Mankhwala odabwitsa apezeka kuti amenyane ndi maselo a khansa. Lero tikambirana za mankhwala apadera otere. Mwachidule, awa amagwira ntchito pochepetsa zakudya, zomwe ndi magazi, a maselo a khansa ndikuchepetsa kukula kwawo.

Kodi Angiogenesis Inhibitors awa ndi chiyani kwenikweni?

Kuti timvetse izi, tiyeni titenge chitsanzo chaching'ono. Tangoganizani, kuti mtengo uliwonse ukule, umafunika kulandira madzi ndi michere nthawi zonse. Mofananamo, kuti chotupa chikule ndikufalikira ku ziwalo zina za thupi, magazi okwanira ndi ofunikira.

Chotupa cha khansa chimakhala chaching'ono kwambiri poyamba. Panthawiyo, chimayamwa michere yomwe chimafunikira kuchokera ku minofu yathanzi yozungulira. Koma chotupacho chikakula kufika pa mamilimita 1-2, chimayenera kupanga njira yatsopano ya mitsempha yamagazi. Monga momwe chomera chimakulira nthambi zatsopano. Kuchokera m'mitsempha yatsopanoyi yamagazi, chotupa cha khansa 'chimadya', chimakula kwambiri, ndikuyamba kufalikira.

Mankhwala apaderawa, otchedwa Angiogenesis Inhibitors , amagwira ntchito poletsa maselo a khansa kupanga mitsempha yatsopano yamagazi. Izi zimachedwetsa kukula kwa maselo a khansa, ndipo nthawi zina maselo amatha kuchepa. Ngakhale kuti chithandizochi sichingathe kuchiza khansa yonse, chingathe kulamulira kukula kwa khansa ndikukulolani kukhala ndi okondedwa anu kwa nthawi yayitali.

Kodi mankhwalawa amagwira ntchito bwanji?

Mankhwalawa amaletsa njira yotchedwa Angiogenesis yomwe imachitika m'thupi lathu. Nthawi zambiri, iyi ndi njira yofunika kwambiri m'thupi lathu. Tangoganizani kuti muli ndi bala m'dzanja lanu. Kenako maselo ovulalawo amatulutsa chizindikiro chapadera (SOS signal) chakuti, 'Tithandizeni!'. Chifukwa cha chizindikirochi, mitsempha yatsopano yamagazi imapanga kuchokera m'mitsempha yamagazi yozungulira bala, zomwe zimapatsa bala magazi ofunikira ndikulichiritsa.

Choyipa kwambiri apa ndichakuti maselo a khansa amagwiritsanso ntchito njira yabwinoyi m'thupi lathu kuti apindule. Amatumizanso zizindikiro zomwezo ndikupanga mitsempha yatsopano yamagazi kuti idyetse yokha.

Zimene Angiogenesis Inhibitors amachita ndi kusokoneza njira yolumikizirana mauthenga.

• Chizindikiro chachikulu mu dongosolo lolumikizirana ili ndi puloteni yotchedwa VEGF (Vascular Endothelial Growth Factor) .
• Puloteni iyi, VEGF, ikalumikizana ndi ma receptors pamwamba pa maselo, imatumiza uthenga kuti mitsempha yatsopano yamagazi ipangidwe.
• Mankhwalawa amaletsa izi m'njira zosiyanasiyana.

Kodi mankhwalawa amagwiritsidwa ntchito pa matenda otani?

Madokotala nthawi zambiri amalimbikitsa chithandizo ichi pa khansa yomwe yapita patsogolo kapena yomwe yabwereranso pambuyo pa chithandizo. Mwachitsanzo:

• Khansa ya muubongo
• Khansa ya m'mawere
• Khansa ya pachibelekero
• Khansa ya m'matumbo
• Khansa ya impso
• Khansa ya chiwindi
• Khansa ya m'mapapo
• Lymphoma ndi Multiple Myeloma
• Khansa ya kapamba
• Khansa ya m'mimba
• Khansa ya chithokomiro
• Khansa ya m'chiberekero

Kuphatikiza apo, mtundu uwu wa mankhwala, wotchedwa VEGF inhibitors, umagwiritsidwanso ntchito pochiza matenda ena a maso omwe amayamba chifukwa cha kukula kosazolowereka kwa mitsempha yamagazi m'maso.

Kodi chimachitika ndi chiyani panthawi ya chithandizo?

Mankhwalawa saperekedwa kawirikawiri okha. Nthawi zambiri amaperekedwa pamodzi ndi mankhwala ena a khansa, monga chemotherapy kapena immunotherapy. Mwachidule, mankhwala oletsa angiogenesis amapha khansa mwa kuiletsa chakudya, pomwe mankhwala ena amapha maselo a khansa mwachindunji.

Kutengera mtundu wa mankhwala omwe mwapatsidwa, mungapatsidwe ngati piritsi kamodzi kapena kawiri patsiku, kapena mungapatsidwe kudzera m'mitsempha (IV) ndi saline kamodzi pa masiku angapo.

Kutalika kwa chithandizo kumadalira mtundu wa mankhwala omwe mwapatsidwa komanso momwe mukudwala. Anthu ena amapitiriza kumwa mankhwalawo bola ngati akugwira ntchito. Ena amasiya kumwa mankhwalawo akalephera kupirira zotsatira zake. Zonsezi zimatheka mwa kulankhula ndi dokotala wanu ndikuwunika zabwino ndi zoyipa za mankhwalawa.

Kodi zoopsa ndi zotsatira zake ndi ziti?

Zina mwa zotsatirapo za mankhwala awa zingakhale zoopsa, choncho ndikofunikira kudziwa izi.

Izi zingamveke zoopsa, koma dokotala wanu nthawi zonse aziyang'anira thanzi lanu ndi kuyezetsa magazi, kotero zoopsazi zitha kuzindikirika ndikuthandizidwa kwambiri.

Kodi ndingathe kudzisamalira bwanji? Kodi ndiyenera kuyimbira dokotala liti?

Chofunika kwambiri chomwe mungachite ndikudziwa bwino za zotsatirapo zake musanayambe kumwa mankhwalawa. Kenako, ngati muwona kusintha kulikonse m'thupi lanu, mutha kuzizindikira mwachangu ndikuuza dokotala wanu. Dokotala wanu angakupatseni mankhwala ena kuti achepetse zotsatirapo zake, kapena kusintha mlingo wa mankhwala omwe mukumwa.

Fufuzani thandizo lachipatala mwamsanga ngati mukukumana ndi zizindikiro zadzidzidzi komanso zachilendo. Makamaka ngati mukukumana ndi zizindikiro za sitiroko kapena matenda a mtima (monga kupweteka kwambiri pachifuwa, kuvutika kupuma, dzanzi pankhope kapena m'miyendo), pitani ku chipatala chapafupi cha Emergency Department (ETU) nthawi yomweyo.

Kodi pali zinthu zomwe zimaletsa izi mwachibadwa?

Inde, zakudya zina zimakhala ndi mankhwala omwe angalepheretse zizindikiro zina zomwe zimachitika mu angiogenesis iyi. Zakudya izi nthawi zambiri zimapezeka mu zakudya za ku Mediterranean. Mwachitsanzo:

• Tiyi wobiriwira
• Mafuta a azitona
• Mphesa zofiyira
• Mtedza
• Katsitsumzukwa

Madokotala akufufuza mankhwala atsopano pogwiritsa ntchito mankhwala achilengedwe awa, koma kafukufuku ameneyu akadali pachiyambi.

Komabe, kudya zakudya zopatsa thanzi kungathandize kwambiri munthu amene akulandira chithandizo cha khansa kukhala wolimba. Choncho, onetsetsani kuti mukudya zakudya zopatsa thanzi.