Kodi thupi lanu ndi louma popanda chifukwa? Tiyeni tikambirane za Stiff Person Syndrome!

Kodi nthawi zina mumamva minofu yanu ikulimba mosadziwika bwino, kapena minofu yanu ikugwedezeka mopweteka? Nthawi zina zimatha kuchitika mukamva phokoso lalikulu kapena wina akukumenyani. Ngati zinthuzi zimachitika kawirikawiri, ndi bwino kuzifufuza. Lero tikambirana za vuto losowa kwambiri lomwe lingayambitse zizindikiro zofanana. Limenelo limatchedwa Stiff Person Syndrome (SPS) .

Kodi Stiff Person Syndrome ndi chiyani?

Mwachidule, Stiff Person Syndrome (SPS) ndi matenda osowa kwambiri amitsempha . Amachitika pamene chitetezo cha mthupi lathu, chomwe chimatiteteza ku matenda, chimaukira maselo athu amitsempha omwe ali ndi thanzi labwino. Ndi vuto la autoimmune. Izi zimapangitsa kuti minofu ya m'mimba mwanu, makamaka mimba yanu, pachifuwa, ndi msana , ikhale yolimba kapena yolimba . Pakapita nthawi, kuuma kumeneku ndi kupindika kumatha kufalikira ku minofu ina ya miyendo ndi manja anu. Izi zingapangitse kuti kuyenda kukhale kovuta, kukupangitsani kugwa pafupipafupi, ndikukupangitsani kuvulala kwambiri.

Poyamba izi zinkatchedwa "stiff man syndrome," koma dzina limenelo lasinthidwa chifukwa matendawa amatha kukhudza aliyense, mosasamala kanthu za msinkhu kapena jenda.

Kupezeka ndi vutoli kungakhale kovuta pang'ono. Koma gulu lanu lachipatala lidzapanga dongosolo la chithandizo lomwe lingakuthandizeni komanso lomwe lingakuthandizeni. Izi zitha kusiyana malinga ndi munthu aliyense. Chofunika kwambiri ndikuwona madokotala anu nthawi zonse, kupeza chithandizo chomwe mukufuna, komanso kuyesetsa kukhala ndi thanzi labwino.

Kodi zizindikiro za Stiff Person Syndrome (SPS) ndi ziti?

Pali zizindikiro ziwiri zazikulu za matendawa:

• Kuuma kapena kuuma kwa minofu.
• Kupweteka kwa minofu.

Ngakhale kuti zizindikirozi zingayambe pa msinkhu uliwonse, nthawi zambiri zimakhalapo pakati pa zaka 30 ndi 40 .

Zizindikiro za Stiff Person Syndrome zimatha kufalikira ku ziwalo zina za thupi ndikukulirakulira pakapita nthawi. Kwa anthu ena, zingatenge miyezi mpaka zaka kuti zizindikiro ziwonekere. Kwa ena, zizindikiro zimatha kukhalabe chimodzimodzi kwa zaka zambiri. Kwa anthu ena, zizindikiro zimatha kukulirakulira pang'onopang'ono ndikupangitsa kuti zikhale zovuta kuchita zinthu za tsiku ndi tsiku.

Kuuma kwa minofu

Kawirikawiri, chizindikiro choyamba chomwe mumachiwona ndi Stiff Person Syndrome ndi kuuma kwa minofu m'thupi . Izi zikutanthauza kuti m'malo monga m'mimba, pachifuwa, ndi msana. Kuuma kumeneku kungayambitse kupweteka ndi kusasangalala. Zizindikirozi zimatha kubwera ndi kutha popanda chifukwa chomveka. Vutoli lingakhudzenso manja ndi miyendo. Pamene kuuma kukuchulukirachulukira, anthu ena amatha kukhala ndi kaimidwe kachilendo komwe kamapangitsa kuti kuyenda kapena kusuntha kukhale kovuta.

Kupweteka kwa minofu

Kupweteka kwa minofu ndi chizindikiro china chachikulu cha vutoli. Izi zingakhudze thupi lonse, kapena zitha kupezeka pamalo enaake. Kupweteka kumeneku kumatha kukhala kwa masekondi, mphindi, kapena maola ambiri. Tangoganizirani, mukangoyimirira, mwadzidzidzi mwendo wanu kapena msana wanu umakhala womangika komanso wovuta. Ndi chokumana nacho chopweteka kwambiri.

Kodi ndi zinthu ziti zomwe zimayambitsa matenda a Stiff Person Syndrome (SPS)?

Pali zifukwa zingapo zomwe zizindikiro monga kugwedezeka kwa minofu zingawonekere mwadzidzidzi:

• Phokoso ladzidzidzi kapena lalikulu. Tangoganizirani ngati mukuyenda mumsewu ndipo galimoto mwadzidzidzi inaimba honi yake, kapena ngati chinachake kunyumba chagwa pansi ndi phokoso lalikulu.
• Kukhudza thupi kapena kukupatsani mphamvu. Ngati wina wakugwira mwadzidzidzi, akukukhudzani.
• Kusintha kwa kutentha, makamaka malo ozizira. Ngati mwadzidzidzi mwapita kumalo ozizira, kapena ngati madzi ozizira agwera pa thupi lanu.
• Zochitika zodetsa nkhawa. Nthawi zokhumudwitsa komanso zoopsa.

Popeza minofu imeneyi imatha kugwedezeka nthawi zina, anthu ena omwe ali ndi Stiff Person Syndrome amakhala ndi nkhawa komanso agoraphobia . Agoraphobia ndi mantha aakulu opita kumalo odzaza anthu, kutuluka panja, kapena kuchoka panyumba. Chifukwa mukatuluka, zimakhala zovuta kuthawa zinthuzi.

Kodi n’chiyani chimayambitsa matenda a Stiff Person Syndrome (SPS)?

Ofufuza sakudziwabe chomwe chimayambitsa matendawa, koma amakhulupirira kuti ndi vuto la autoimmune, zomwe zikutanthauza kuti chitetezo cha mthupi lathu chimaukira maselo athanzi.

Kafukufuku wasonyeza kuti ma antibodies amakhudzidwa. Anthu ambiri omwe ali ndi Stiff Person Syndrome ali ndi ma antibodies motsutsana ndi enzyme yotchedwa Glutamic Acid Decarboxylase (GAD) . Enzyme iyi (GAD) imathandiza kupanga neurotransmitter gamma-aminobutyric acid (GABA) . Neurotransmitter iyi (GABA) imathandiza kuwongolera magwiridwe antchito a minofu.

Koma ofufuza sakumvetsabe bwino momwe enzyme `(GAD)` imakhudzira kukula ndi kupita patsogolo kwa Stiff Person Syndrome. Chinthu chimodzi choyenera kukumbukira ndichakuti kukhala ndi ma antibodies `(GAD)` m'thupi lanu sikutanthauza kuti muli ndi Stiff Person Syndrome. Anthu ochepa akhoza kukhala ndi ma antibodies awa `(GAD)` m'thupi lawo popanda zotsatirapo zoyipa.

Kuwonjezera pa GAD, ma antibodies ena monga glycine receptor, amphiphysin, ndi DPPX (dipeptidyl peptidase-like protein 6) apezeka kuti akugwirizana ndi matendawa. Komanso, odwala ena sangakhale ndi ma antibodies awa. Kafukufuku wina akupitilira kuti adziwe ma antibodies ena omwe angakhale nawo.

Kodi ndi zinthu ziti zomwe zimayambitsa matenda a Stiff Person Syndrome (SPS)?

Matenda a munthu wolimba (stiff person syndrome) amapezeka kawiri mwa akazi . Amathanso kuchitika ndi matenda ena a autoimmune. Mwachitsanzo:

• Matenda a shuga amtundu woyamba
• Matenda a chithokomiro odziteteza okha
• Vitiligo
• Kuchepa kwa magazi m'thupi koopsa
• Matenda a Celiac

Kodi matenda a Stiff Person Syndrome (SPS) ndi ofala bwanji?

Uwu ndi matenda osowa kwambiri . Akuti munthu m'modzi yekha pa anthu miliyoni ali ndi matendawa. Izi zikutanthauza kuti ndi matenda osowa kwambiri.

Kodi matenda a Stiff Person Syndrome (SPS) amapezedwa bwanji?

Dokotala amazindikira matendawa kudzera mu zizindikiro zinazake, mayeso, ndi mayeso. Adzakufunsani za zizindikiro zanu, adzakuyezani thupi, komanso adzakuyezani ndi ubongo.

Ngati dokotala akukayikira kuti ali ndi Stiff Person Syndrome, akhoza kuchita mayeso monga:

• Kuyezetsa magazi kwa ma antibodies: Izi zimathandiza kuwona ngati pali ma antibodies ku (GAD) (kapena ma antibodies ena ofanana nawo) komanso kupewa matenda ena.
• Electromyography (EMG): Izi zimayesa mphamvu yamagetsi ya minofu yanu. Izi zingathandize kuchotsa zifukwa zina zomwe zimayambitsa zizindikiro zanu.
• Kuboola msana (kupopera msana): Mu mayesowa, dokotala amagwiritsa ntchito singano kuti atenge chitsanzo cha madzi kuchokera ku msana wanu ndikuyesa ngati ali ndi ma antibodies ku GAD. Izi ndizofunikiranso kuti athetse matenda ena.

Matenda a Stiff Person Syndrome amatha kukhala ovuta kuwazindikira chifukwa ndi osowa ndipo zizindikiro zake zimatha kufanana ndi matenda ena odziteteza okha, monga ankylosing spondylitis ndi multiple sclerosis.

Kodi pali mitundu ya matenda a Stiff Person Syndrome (SPS)?

Pali mitundu yosiyanasiyana ya matendawa:

• Matenda a munthu wolimba mtima: Uwu ndi mtundu wofala kwambiri. Nthawi zambiri umagwirizanitsidwa ndi ma antibodies a GAD, koma kafukufuku wapeza kuti ma antibodies ena nawonso amakhudzidwa.
• Mitundu ya matenda a munthu wolimba:Pansi pa izi, pali mitundu yosiyanasiyana yomwe imakhudza ziwalo zinazake za thupi, kapena yomwe imawonetsa zizindikiro zambiri monga kutaya mphamvu mukuyenda (`ataxia`).
• Matenda a progressive encephalomyelitis okhala ndi kuuma ndi myoclonus (PERM): PERM ndi mtundu woopsa kwambiri wa matenda a stiff person syndrome. Angayambitse kutaya chidziwitso, mavuto oyenda ndi maso, ataxia, komanso kusagwira bwino ntchito kwa autonomic. Kusagwira bwino ntchito kwa autonomic kumafuna kuti anthu omwe ali ndi PERM agonekedwe m'chipatala.

Kodi matenda a Stiff Person Syndrome (SPS) amachiritsidwa bwanji?

Pali njira ziwiri zazikulu zochizira izi:

• Mankhwala ndi mankhwala oletsa zizindikiro.
• Chithandizo cha immunotherapy, kapena chithandizo chosintha matenda.

Njira zochiritsira zimasiyana malinga ndi zizindikiro zanu. Cholinga chachikulu cha chithandizo ndikuwongolera momwe zizindikiro zanu zimakukhudzirani ndikuwonjezera kuyenda kwanu komanso chitonthozo chanu.

Gulu lanu lachipatala lingakhale ndi akatswiri angapo, monga:

• Akatswiri a za ubongo, makamaka akatswiri a zaubongo.
• Akatswiri a zamaganizo ndi akatswiri a zamaganizo.
• Akatswiri azachipatala ndi ochiritsa odwala.
• Akatswiri ochiritsa kulankhula.
• Akatswiri azaumoyo wamaganizo, mwachitsanzo akatswiri a zamaganizo.

Mankhwala ndi mankhwala

Mankhwala ngati awa angathandize kuchepetsa kuuma kwa minofu, kuuma, komanso kupweteka kwa minofu:

• Benzodiazepines: Awa ndi gulu la mankhwala omwe amagwiritsidwa ntchito pochiza matenda osiyanasiyana, kuphatikizapo nkhawa, khunyu, ndi kusowa tulo. Amakhudza chizindikiro cha neurotransmitter (GABA). Madokotala nthawi zambiri amalemba diazepam ngati chithandizo choyamba cha Stiff Person Syndrome.
• Mankhwala opumitsa minofu: Mankhwala monga Baclofen angathandize ndi kupweteka kwa minofu. Amapumitsa minofu ndikuchepetsa kuuma.
• Mankhwala opweteka a neuropathic: Mankhwala monga gabapentin ndi pregabalin amakhudzanso zizindikiro za GABA ndikuthandizira zizindikiro.

Mankhwala ena omwe angathandize kuchepetsa zizindikiro ndi awa:

• Kuchiza thupi kapena chithandizo cha ntchito.
• Kusisita.
• Hydrotherapy (chithandizo cha madzi).
• Chithandizo cha kutentha.
• Kuchiza ndi acupuncture.

Chithandizo cha Immunotherapy

Pali umboni wina wosonyeza kuti chithandizo cha immunoglobulin (IVIg) m'mitsempha (komanso mtundu wa chithandizo cha immunotherapy) chingathandize kuchepetsa zizindikiro za Stiff Person Syndrome. IVIg ili ndi ma immunoglobulin (ma antibodies achilengedwe) omwe amaperekedwa ndi anthu zikwizikwi omwe ali ndi chitetezo chamthupi chathanzi.

Kodi matenda a Stiff Person Syndrome (SPS) angachiritsidwe?

Pakadali pano, palibe mankhwala a Stiff Person Syndrome. Chithandizo chingathandize kuchepetsa zizindikiro zokha.

Kodi chiyembekezo cha matenda a Stiff Person Syndrome (SPS) ndi chotani?

Uwu ndi matenda osatha omwe amachitika kwa moyo wonse . Kawonedwe ka anthu kamasiyana malinga ndi zinthu zingapo:

• Kuopsa kwa zizindikiro.
• Kuthamanga kwa matendawa kunafalikira.
• Kodi chithandizochi chikuyenda bwino bwanji?

Ndikofunikira kuyamba chithandizo zizindikiro zikayamba. Izi zingathandize kupewa kapena kuchepetsa kufalikira kwa matendawa komanso kupewa mavuto omwe angakhalepo kwa nthawi yayitali. Ngakhale anthu ambiri amapeza mpumulo ndi mankhwala, nthawi zina zimakhala zovuta kulamulira zomwe zimayambitsa kupweteka kwa minofu.

Kuyenda kungakhale kovuta kwambiri pakapita nthawi. Kutha kuchita zinthu za tsiku ndi tsiku kungachepe pang'onopang'ono. Pamene matendawa akupitirira, chiopsezo chogwa chimawonjezeka. Mungafunike kugwiritsa ntchito ndodo, choyendera, kapena ngakhale mpando wa olumala.

Kodi Matenda a Munthu Wolimba (SPS) angapewedwe?

Popeza uwu ndi matenda odziteteza okha, palibe chomwe mungachite kuti mupewe .

Kodi ndimadzisamalira bwanji ngati ndili ndi Stiff Person Syndrome (SPS)?

Ngati n'kotheka, yesani kupeza dokotala yemwe ndi katswiri wofufuza ndi kuchiza matenda a Stiff Person Syndrome. Matendawa ndi osowa, kotero amatha kukhala ovuta pang'ono. Ngati mukufuna kupeza chithandizo chamankhwala chabwino kwambiri komanso kukhala ndi moyo wabwino kwambiri, muyenera kulankhula ndikukhala ndi chidwi ndi vutoli.

Anthu omwe ali ndi matendawa nthawi zambiri amakhala ndi mavuto amisala monga nkhawa kapena kuvutika maganizo . Ngati mukukumana ndi zizindikirozi, ndikofunikira kulankhula ndi dokotala wanu kapena katswiri wa zamaganizo, monga katswiri wa zamaganizo.

Ngati inu ndi banja lanu mungathe, mutha kulowa nawo gulu lothandizira komwe mungakumane ndi ena omwe akumvetsa zomwe mwakumana nazo.

Kodi ndiyenera kupita kwa dokotala liti?

Ngati muli ndi Stiff Person Syndrome, muyenera kukumana ndi gulu lanu lachipatala nthawi zonse kuti muwone ngati chithandizo chanu chapambana komanso kuti muwone momwe zizindikiro zanu zikukulirakulira.

Ngati muwona zizindikiro zatsopano kapena muli ndi zotsatirapo zoyipa kuchokera ku mankhwala, uzani dokotala wanu.

Ndi mafunso ati omwe ndiyenera kufunsa dokotala wanga?

Ngati muli ndi Stiff Person Syndrome, zingakhale zothandiza kufunsa dokotala wanu mafunso awa:

• Kodi ndi mankhwala ati omwe mumalimbikitsa pa zizindikiro zanga?
• Kodi ndingachite chiyani kunyumba kuti ndithandize ndi zizindikiro zanga?
• Ndi zizindikiro ziti za mavuto zomwe ndiyenera kuyang'anitsitsa?
• Kodi ndingayembekezere kuti thanzi langa lidzakhala bwanji mtsogolo?
• Kodi pali mayeso azachipatala a Stiff Person Syndrome?

Pomaliza, zinthu zoti muzikumbukira (Uthenga Wopita Nawo Kunyumba)

Kudziwa kuti muli ndi matenda osowa monga Stiff Person Syndrome sikophweka. Mungamve ngati mukuvutika maganizo, mukuda nkhawa, komanso simukudziwa za tsogolo lanu. Koma simuyenera kukumana ndi vutoli nokha. Gulu lanu lachipatala lili pano kuti liyankhe mafunso aliwonse omwe mungakhale nawo ndikukuthandizani kuthana ndi zizindikiro zanu.

Ngakhale kuti chithandizo chanu chimayang'ana kwambiri thanzi lanu lakuthupi, samalaninso za thanzi lanu la maganizo . Zizindikiro zimasiyana malinga ndi munthu. Koma kukhala ndi ululu, kusapeza bwino, komanso kugwedezeka kwa minofu kosayembekezereka kungakuwonongereni thanzi lanu la maganizo. Vutoli lingakupangitseni kukhala kovuta kutuluka ndikuchita zinthu za tsiku ndi tsiku. Chifukwa chake, ngati mukufuna thandizo, musazengereze kulumikizana ndi dokotala kuwonjezera pa okondedwa anu. Kumbukirani, simuli nokha.

Matenda a Munthu Wolimba, kuuma kwa minofu, matenda amitsempha, autoimmune, ma antibodies a GAD, GABA, kugwedezeka kwa minofu, zizindikiro za SPS