Kodi inunso mukuwonetsa zizindikiro za ukalamba msanga? Tiyeni tikambirane za matenda a Werner Syndrome!

Kodi mumamva ngati mukuwoneka ngati wamkulu kuposa zaka zanu? Ngakhale kuti nthawi zina ndi zachilendo kumva choncho, kukalamba msanga, kapena thupi kukalamba mofulumira, kungayambitsidwe ndi matenda osowa kwambiri a majini. Chimodzi mwa matenda amenewa ndi Werner Syndrome. Tiyeni tikambirane za izi mwatsatanetsatane lero, chifukwa ndikofunikira kwambiri kudziwa za izi.

Kodi Werner Syndrome ndi chiyani?

Mwachidule, Werner Syndrome ndi matenda osowa kwambiri omwe amachititsa kuti thupi lanu likalamba mofulumira kwambiri kuposa momwe limayembekezera. Anthu ena amatcha 'adult progeria'. Zizindikiro nthawi zambiri sizimawonekera mpaka mutafika msinkhu wokhwima. Izi zikutanthauza kuti mudzayamba kuona kusiyana mukasiya kukula mofulumira ngati anzanu. Kenako, muzaka za m'ma 20, mudzayamba kuona zizindikiro za ukalamba - ndipo, pakapita nthawi, matenda omwe amabwera ndi ukalamba.

Koma izi sizikutanthauza kuti tsitsi limayamba kuoneka imvi komanso khungu limafooka. Kukalamba sikutanthauza kusintha maonekedwe kokha. Anthu ambiri omwe ali ndi matenda a Werner Syndrome amakhala ndi mavuto omwe angawaphe akafika zaka za m'ma 40 ndi 50.

Kodi zizindikiro zimenezi ndi ziti?

Mukakhala ndi Werner Syndrome, zizindikiro zake zimaonekera kwambiri mukamakula. Mungayambe kuzindikira zizindikiro za ukalamba msanga kuposa ena omwe ali ndi zaka zanu, ali ndi zaka 20. Nazi zina mwa zizindikirozi:

Kusintha kwa mawonekedwe

• Kutuwa kwa tsitsi ndi kutayika kwa tsitsi: Izi sizikuphatikizapo tsitsi la pamutu lokha, komanso nsidze ndi nsidze.
• Mawu akumveka mokweza kapena mokweza.
• Kuchepa kwa minofu ya mafuta m'thupi: Izi zingayambitse khungu kuoneka ngati likugwa.
• Kufooka kwa minofu.
• Kuola mano msanga.
• Kuda kwa madera ena a khungu (hyperpigmentation) kapena kuwunika kwa madera ena (hypopigmentation).
• Kufiira kwa khungu chifukwa cha mitsempha yamagazi yotambasuka.
• Khungu limakhuthala kapena kuuma: Izi zikufanana pang'ono ndi matenda otchedwa scleroderma.
• Nkhope yopsinjika komanso yovutika maganizo.

Mavuto ena azaumoyo omwe amachokera mkati mwa thupi

Ndi Werner Syndrome, simumangooneka ngati wokalamba. Thupi lanu limakalamba mofulumira kuposa msinkhu wanu weniweni. Izi zikutanthauza kuti mungakhalenso ndi mavuto ena azaumoyo msanga kuposa momwe mumayembekezera. Izi zikuphatikizapo:

• Matenda a shuga amtundu wachiwiri: Ndipotu, anthu pafupifupi 7 pa anthu 10 aliwonse omwe ali ndi matenda a shuga a mtundu wachiwiri amayamba kudwala matenda a shuga amtundu wachiwiri akafika zaka 35.
• Hypogonadism (kulephera kugwira ntchito m'mazira kapena m'machende).
• Zilonda za pakhungu.
• Kuchepa kwa mafupa (osteoporosis).
• Matenda a atherosclerosis.
• Matenda a cataract kapena macular degeneration.
• Kupweteka pachifuwa (angina).
• Kutsekeka kwa mtima.
• Kulephera kwa mtima `(kulephera kwa mtima)`.

Kuopsa kwa khansa

Anthu omwe ali ndi matenda a Werner Syndrome ali pachiwopsezo chachikulu chotenga mitundu ina ya khansa. Mwachitsanzo:

• Khansa ya chithokomiro.
• Khansa ya pakhungu (Melanoma).
• Osteosarcoma (khansa ya mafupa).
• Sarcoma yofewa ya minofu.

Kodi n’chiyani chimayambitsa matenda a Werner?

Imeneyi ndi matenda a majini . Izi zikutanthauza kuti, amayamba chifukwa cha kusintha kwa majini athu. Matenda a Werner amapezeka mwa anthu omwe ali ndi zolakwika ziwiri mu jini ya WRN. Nthawi zambiri, limodzi mwa majini awiriwa olakwika limatengera kwa amayi ndi lina kuchokera kwa abambo.

Kodi mumapeza bwanji izi? (Kuzindikira)

Dokotala wanu adzafufuza njira zina zodziwira matenda a Werner Syndrome. Akhozanso kuyitanitsa mayeso awa:

• Mayeso a majini: Yang'anani kusintha kwa majini komwe kumayambitsa Werner Syndrome.
• X-ray: Yang'anani ngati mafupa asintha kapena ngati pali zotupa.

Madokotala nthawi zina amatha kuzindikira matenda a Werner Syndrome ali ndi zaka 15. Komabe, matendawa nthawi zambiri amapezeka m'zaka za m'ma 30 kapena 40. Izi zili choncho chifukwa zizindikiro zina za matendawa zimatenga nthawi yayitali kuti ziwonekere.

Kodi mankhwala ake ndi otani?

Matenda a Werner Syndrome amachiritsidwa kutengera zizindikiro zomwe zimawonekera. Izi zikutanthauza kuti chithandizo chimodzi sichigwira ntchito kwa aliyense. Akatswiri angapo angagwire ntchito limodzi kuti agwirizane ndi dongosolo lanu la chithandizo. Mwachitsanzo:

• Akatswiri a Endocrinologists (akatswiri a mahomoni).
• Madokotala a maso ( akatswiri a maso).
• Madokotala a mafupa (akatswiri a mafupa ndi mafupa).

Mankhwala omwe mumalandira angaphatikizepo:

• Mankhwala a shuga: Yang'anirani kuchuluka kwa shuga m'magazi mwanu.
• Magalasi kapena ma contact lens: Konzani mavuto a maso.
• Mankhwala a matenda a mtima:Kuchepetsa chiopsezo cha mavuto mwa kulamulira atherosclerosis.
• Opaleshoni: Ngati pali zotupa za khansa, zichotseni.

Kodi matenda a Werner Syndrome angapewedwe?

Chifukwa chakuti uwu ndi matenda a majini, mwatsoka, Werner Syndrome singathe kupewedwa.

Komabe, ngati inu ndi mnzanu muli ndi jini ya vutoli, ndipo mukufunanso kukhala ndi ana, mungafune kuganizira njira yotchedwa preimplantation genetic testing (PGT). PGT ndi kuphatikiza kwa majini ndi in vitro fertilization (IVF). Izi zimaphatikizapo kuyesa mazira asanaikidwe m'chiberekero kuti achepetse mwayi woti ana alandire matenda a majini awa. Komabe, njirazi ndi zovuta kwambiri, kotero zisankho ziyenera kupangidwa pokhapokha ngati dokotala apereka upangiri.

Ndi chiyani china chomwe mungafune kufunsa dokotala wanu?

Ngati muli ndi Werner Syndrome, ndikofunika kufunsa dokotala wanu mafunso onse omwe muli nawo. Mwachitsanzo, mungafunse zinthu monga:

• Kodi ndi bwino kuti ndikapimidwe majini a Werner Syndrome?
• Kodi njira zochiritsira matenda a Werner Syndrome ndi ziti?
• Kodi ndiyenera kuchita chiyani kuti ndichepetse chiopsezo changa cha khansa?
• Kodi ndi mayeso ati omwe ndiyenera kuchita kuti ndipewe mavuto a Werner Syndrome?
• Kodi pali mwayi wotani woti ana anga adzalandira matenda a Werner Syndrome kuchokera kwa ine?
• Kodi mwayi wanga woti ndikhale ndi mwana wina ndi Werner Syndrome ndi wotani?

Ndi matenda ena ati omwe ali ndi zizindikiro zofanana?

Kuwonjezera pa Werner Syndrome, palinso matenda ena ambiri omwe amayambitsa kufupika kwa thupi komanso kukalamba msanga. Izi zikuphatikizapo:

• Matenda a De Barsy
• Matenda a Gottron
• Hutchinson-Gilford syndrome (iyi ndi mtundu wa Progeria womwe umakhudza ana aang'ono)
• Matenda a Mulvihill-Smith
• Matenda a Rothmund-Thomson
• Matenda a mphepo yamkuntho

Zonsezi ndi matenda osowa kwambiri, choncho ndikofunikira kwambiri kupeza matenda olondola.

Mbiri yochepa yokhudza matenda a Werner Syndrome ndipo ndi yofala bwanji?

Matenda a Werner Syndrome adapezeka koyamba kumayambiriro kwa zaka za m'ma 1900 ndi dokotala dzina lake Otto Werner. Zizindikiro ziwiri zomwe adaziona koyamba mwa odwala achichepere zinali ma cataract ndi mawanga akuda onyezimira pakhungu.

Uwu ndi matenda osowa kwambiri. Kuyambira pomwe lipoti loyamba la matendawa linasindikizidwa mu 1904, milandu pafupifupi 800 yokha ndi yomwe yalembedwa m'magazini azachipatala.

Ku United States, akatswiri akuti munthu m'modzi pa anthu 200,000 aliwonse ali ndi matenda a Werner Syndrome. Padziko lonse lapansi, matendawa ndi ochepa kwambiri moti munthu m'modzi pa anthu miliyoni imodzi amawapeza.

Komabe, matendawa amapezeka kwambiri ku Japan ndi m'chigawo cha Sardinia ku Italy. Kumeneko, pafupifupi munthu mmodzi pa anthu 30,000 kapena 50,000 ali ndi vutoli. Chifukwa chake n'chakuti anthu ambiri m'madera amenewo adalandira kusintha kwa majini komwe kunachitika m'mibadwo yakale.

Kupeza kuti inuyo kapena wokondedwa wanu ali ndi matenda a Werner Syndrome kungakhale kovuta. Zingakhale zokhumudwitsa chifukwa palibe mankhwala. Komabe, chithandizo chingachepetse chiopsezo cha mavuto omwe angawononge moyo.

Pomaliza, uthenga wopita nawo kunyumba

Matenda a Werner ndi vuto lovuta kwambiri, koma kumbukirani kuti simuli nokha.

• Pezani chithandizo choyenera chamankhwala ndi upangiri: Izi zidzakuthandizani kuthana ndi zizindikiro zanu ndikukweza moyo wanu.
• Tsatirani moyo wathanzi: Gonani mokwanira, idyani zakudya zopatsa thanzi, gwiritsani ntchito mafuta oteteza ku dzuwa mukatuluka padzuwa, ndipo yesetsani kuchepetsa nkhawa. Zinthu zimenezi zidzakuthandizani kukhala ndi thanzi labwino.
• Funani thandizo: Funsani gulu lanu lachipatala za magulu othandizira. Mwina simukumva kupanikizika kwambiri pakadali pano, koma sungani chidziwitsocho pafupi. Chingakuthandizeni mtsogolo.

Kukhala ndi matenda osowa ngati awa sikophweka. Koma ndi chidziwitso choyenera, chithandizo, komanso malingaliro abwino, mudzapeza mphamvu zoyendera ulendowu.

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