Kodi muli ndi enzyme yochepa ya G6PD? Tiyeni tikambirane za izi! (Kusowa kwa G6PD)

Kodi nthawi zina mumamva kutopa kwambiri kapena kutopa popanda chifukwa? Kodi khungu lanu limawoneka lachikasu? Kapena kodi jaundice ya mwana wanu wakhanda siimatha patatha milungu iwiri? Chifukwa cha zinthuzi chikhoza kukhala kusowa kwa enzyme yotchedwa G6PD m'thupi lanu. Musadandaule, iyi ndi vuto lofala kwambiri. Lero, tikambirana momveka bwino za G6PD, zomwe zimachitika ikachepa, komanso mayeso a G6PD.

Kodi G6PD ndi chiyani kwenikweni?

Taganizirani maselo ofiira a magazi m'thupi lathu ngati asilikali ogwira ntchito. Pali 'mlonda' amene amateteza asilikaliwa ku zinthu zosiyanasiyana zoopsa. Mlonda ameneyo ndi enzyme yotchedwa G6PD.

Mwachidule, G6PD (Glucose-6-Phosphate Dehydrogenase) ndi enzyme yofunika kwambiri yomwe imateteza maselo athu, makamaka maselo ofiira a m'magazi athu, ku mankhwala owopsa. Thupi lathu limapanga zinthu zovulaza (zomwe zimatchedwanso 'Free Radicals' kapena 'Reactive Oxygen Species' ) zomwe zimapangidwa nthawi yomwe ikugwira ntchito bwino. Enzyme ya G6PD imachita izi poletsa zinthu zovulaza izi kuti zisasonkhanitse ndikuwononga maselo.

Kodi chimachitika ndi chiyani ngati G6PD yatsika?

Tsopano taganizirani zomwe zimachitika ngati 'protector' (G6PD) imeneyo ili yochepa m'thupi? Kenako zinthu zoopsazo zimabwera ndikuyamba kuwononga maselo athu ofiira a magazi. Njira imeneyi ya maselo ofiira a magazi kusweka mofulumira kuposa momwe angapangidwire imatchedwa hemolysis .

Kodi kusowa kwa G6PD kumachitika bwanji?

Kusowa kwa G6PD ndi matenda obadwa nawo a majini . Izi zikutanthauza kuti ndi chinthu chomwe mumalandira kuchokera kwa makolo anu. Pakakhala kusintha kwa majini komwe kumakulangizani kuti mupange enzyme ya G6PD, kuchuluka kwa enzyme iyi yomwe imapangidwa m'thupi kumachepa.

Koma chofunika apa ndichakuti si aliyense amene ali ndi vuto la G6PD amene adzakhale ndi zizindikiro. Anthu ambiri amakhala moyo wabwinobwino popanda mavuto. Komabe, zinthu zina zakunja (zomwe timazitcha 'zoyambitsa') zingayambitse zizindikiro mwadzidzidzi.

Zinthu zomwe zimayambitsa zizindikiro za G6PD

Zinthu zimenezi zimapangitsa thupi kuchulukitsa mwadzidzidzi kuchuluka kwa 'free radicals' yoopsa yomwe tidakambirana. Munthu amene ali ndi vuto la G6PD sangathe kulamulira zinthu zoopsazi zomwe zikuchulukirachulukira. Pamenepo ndi pomwe maselo ofiira amagazi amayamba kusweka, ndipo zizindikiro zimawonekera.

Kusowa kwa G6PD kumachitika kwambiri mwa amuna kuposa akazi, ndipo kumachitika kwambiri mwa anthu a ku Africa, Asia, ndi Mediterranean.

Ndani ayenera kutenga mayeso a G6PD?

Dokotala wanu angakulangizeni kuti muyesedwe magazi a G6PD (kuyezetsa magazi kosavuta), makamaka ngati muli ndi zizindikiro zotsatirazi:

• Kutopa ndi kufooka kosaneneka
• Khungu lotumbululuka
• Kuvuta kupuma kapena kupuma movutikira
• Kugunda kwa mtima
• Kuoneka kwachikasu pakhungu ndi m'maso (jaundice)
• Mkodzo wakuda (wamtundu wa cola)
• Kupweteka kumbuyo kapena m'mimba
• Mkhalidwe wa chisokonezo womwe ulipo panopa

Samalani kwambiri makanda obadwa kumene.

Ndi zachilendo kuti mwana wakhanda akhale ndi matenda a jaundice. Koma ngati apitirira milungu iwiri , mkodzo wa mwana umasintha kukhala wakuda, ndipo ndowe zake zimasintha mtundu, dokotala angaganize kuti ali ndi vuto la G6PD ndipo angamuyesere.

Kodi mungamvetse bwanji lipoti la mayeso?

Zotsatira za mayeso a G6PD zimatha kusiyana pang'ono kuchokera ku labu ina kupita ku ina, kotero dokotala wanu yekha ndi amene angakupatseni chidziwitso cholondola kwambiri . Komabe, nthawi zambiri pali mitundu itatu ya zotsatira.

• Zachibadwa: Muli ndi enzyme yokwanira ya G6PD m'thupi lanu. Mulibe kusowa kwa G6PD.
• Kusowa kwapakati: Mulingo wa ma enzyme uli pakati pa 10% ndi 60% wa wabwinobwino. Anthuwa nthawi zambiri amamva zizindikiro zokha akadwala matenda kapena akalandira mankhwala osayenera.
• Kusowa Kwambiri kwa Maselo: Enzymeyi imapezeka pamlingo wochepera 10% wa thupi labwinobwino. Anthuwa akhoza kukhala ndi kuchepa kwa magazi m'thupi kosalekeza kapena zizindikiro zobwerezabwereza.

Kuchiza ndi kusamalira kusowa kwa G6PD

Kusowa kwa G6PD si matenda ochiritsika kwathunthu, chifukwa ndi matenda obadwa nawo. Komabe, ngati mutathandizidwa bwino, mutha kukhala ndi moyo wathanzi popanda mavuto .

Muyenera:

• Pewani kudya nyemba za fava kwathunthu.
• Pewani kumwa mankhwala ochepetsa ululu monga Aspirin ndi Acetaminophen (Paracetamol) popanda chilolezo cha dokotala.
• Uzani dokotala wanu kuti muli ndi vuto la kuchepa kwa G6PD musanapereke mankhwala aliwonse .
• Fufuzani thandizo lachipatala nthawi yomweyo ngati mwayamba matenda aliwonse.

Ngati zizindikiro zanu zili zochepa, dokotala wanu angakulembereni mapiritsi a folic acid ndi iron. Ngati kuchepa kwa magazi m'thupi lanu kuli kwakukulu, mungafunike kupita kuchipatala ndikupatsidwa magazi kapena chithandizo cha okosijeni.

Kumbukirani kuti ma antioxidants monga Vitamini E sangathandize vutoli.