Kodi mwana wanu amadwala nthawi zambiri? Kodi ndi WHIM Syndrome yosowa?

Kodi mwana wanu nthawi zambiri amadwala chimfine, chifuwa, matenda a m'makutu, kapena matenda a pakhungu? Kodi matenda ena amachira msanga kuposa ena? Nthawi zambiri, timaganiza kuti chitetezo cha mthupi cha mwana chimakhala chochepa pang'ono ndipo amatenga matenda kusukulu ndi m'malo osewerera. Komabe, nthawi zina, izi zimatha kuchitika chifukwa cha matenda enaake otchedwa WHIM Syndrome . Ngakhale kuti izi sizikunenedwa kwambiri, ndikofunikira kudziwa za izi.

Kodi vuto la WHIM limeneli ndi chiyani?

Mwachidule, matenda a WHIM ndi matenda osowa kwambiri omwe amakhudza chitetezo cha mthupi lathu. Dzina lakuti WHIM limachokera ku zilembo zoyambirira za zizindikiro zinayi zazikulu za matendawa.

• Ma warts (ma warts)
• Hypogammaglobulinemia (kuchepa kwa ma antibodies m'magazi)
• Matenda (matenda ofala)
• Kutuluka magazi m'magazi (kutsekeka kwa maselo oyera m'magazi)

Tangoganizani kuti thupi lathu lili ndi gulu lankhondo la maselo oyera amagazi. Ntchito ya asilikaliwa ndi kulimbana ndi adani monga mabakiteriya ndi mavairasi omwe amayambitsa matenda. Kwa munthu amene ali ndi matenda a WHIM, asilikali ofunikira kwambiri m'gululi, maselo oyera amagazi otchedwa neutrophils , amamatira m'munsi mwawo, m'mafupa. Sangathe kutuluka, m'magazi, kuti akamenyane ndi matenda. Chifukwa chake, chitetezo cha thupi chimafooka, ndipo amayamba kudwala pafupipafupi.

Kodi zizindikiro za matenda a WHIM ndi ziti?

Zizindikiro zimenezi zimatha kusiyana kwambiri malinga ndi munthu. Anthu ena amakhala ndi zizindikiro zochepa kwambiri. Ena amatha kutenga matenda oopsa omwe angawononge moyo wawo. Zizindikiro zimenezi nthawi zambiri zimayamba ali ana, koma nthawi zina matendawa sangadziwike mpaka atakula.

Makamaka za ziphuphu ndi chiopsezo cha khansa

Anthu ambiri otizungulira akhoza kutenga kachilombo ka human papillomavirus (HPV), komwe kamayambitsa ziphuphu. Komabe, mwa munthu amene ali ndi chitetezo chamthupi chathanzi, kachilomboka kamatha kuchoka m'thupi pafupifupi nthawi yomweyo. Komabe, chifukwa chitetezo chamthupi cha munthu amene ali ndi matenda a WHIM ndi chofooka, zimakhala zovuta kulimbana ndi kachilombo ka HPV. Chifukwa chake, kachilomboka kamakhalabe m'thupi kwa nthawi yayitali, zomwe zimayambitsa ziphuphu, ndipo nthawi zina, zimawonjezera chiopsezo cha khansa.

Kodi izi zimayambitsa chiyani? Kodi izi ndi zopatsirana?

Chifukwa chachikulu cha matenda a WHIM ndi kusintha kwa majini otchedwa `CXCR4` m'thupi lathu. Taganizirani za majini awa ngati pulogalamu yomwe imaphunzitsa maselo athu. Majini awa akasintha, maselo oyera amagazi (Neutrophils) omwe atchulidwa pamwambapa amasiya kutuluka mu mafupa.

Popeza ili ndi vuto la majini, silingafalitsidwe kuchokera kwa munthu wina kupita kwa wina kudzera mu kuyetsemula kapena kugwirana . Komabe, likhoza kufalikira kuchokera kwa makolo kupita kwa ana. Ngati kholo lililonse lili ndi kusintha kwa majini kumeneku, mwana aliyense amene ali naye ali ndi mwayi wa 50% wolandira vutoli .

Kodi mumazindikira bwanji matendawa molondola?

Popeza matenda amenewa ndi osowa kwambiri, n'zovuta kuwazindikira ndi mayeso amodzi okha. Dokotala wanu adzakuyang'anirani mosamala zizindikiro zanu ndi za mwana wanu, kuchuluka kwa matenda omwe amadwala, kenako angakulangizeni mayeso angapo.

• Kuchuluka kwa Magazi Okwanira (CBC): Izi zimayang'ana maselo oyera otsika m'magazi, makamaka ma neutrophils, m'magazi.
• Kuyesa kwa ma antibodies (kuyesa magazi a Immunoglobulin G - IgG):Kuyesaku kumachitika kuti awone ngati ma antibodies omwe amalimbana ndi matenda ndi otsika.
• Kufufuza Mafupa: Mu njira imeneyi, chitsanzo chaching'ono cha mafuta a m'mafupa chimatengedwa kuchokera ku fupa la m'chiuno mothandizidwa ndi mankhwala oletsa ululu pang'ono ndikuwunikidwa pogwiritsa ntchito maikulosikopu. Izi zitha kudziwa molondola ngati maselo oyera amagazi ali mu mafuta a m'mafupa (myelokathexis).
• Kuyesa Majini: Kuyesa kumeneku kungatsimikizire ngati pali kusintha kwa majini a `CXCR4` komwe kumayambitsa matenda a WHIM.

Kodi mankhwala a WHIM syndrome ndi ati?

Palibe mankhwala a vutoli pakadali pano. Komabe, pali njira zingapo zothandizira zomwe zingathandize kuchepetsa zizindikiro, kuteteza ku matenda, komanso kukuthandizani kukhala ndi moyo wabwinobwino.

Mitundu ya mankhwala

• Xolremdi: Iyi ndi mankhwala atsopano omwe adavomerezedwa mu 2024. Amathandiza kutulutsa maselo oyera amagazi omwe amakhala mum'mafupa. Izi zitha kuchepetsa chiopsezo cha matenda ndi pafupifupi 40%.
• Chithandizo cha G-CSF: Ichi ndi jakisoni. Chimalimbikitsa mafuta a m'mafupa ndipo chimathandiza kuti apange maselo oyera ambiri amagazi.
• Chithandizo cha IgG: Kwa iwo omwe ali ndi ma antibodies ochepa, chitetezo cha mthupi chimalimbikitsidwa powapatsa ma antibodies ochokera kunja.
• Mankhwala opha tizilombo toyambitsa matenda: Matenda a bakiteriya akayamba (monga chibayo, matenda a pakhungu), dokotala wanu adzakupatsani mankhwala awa kuti awachepetse.

Chithandizo cha ziphuphu

Ngati ziphuphu zimachitika pafupipafupi, mutha kuwonana ndi dokotala wa khungu kuti achotsedwe. Pali njira zingapo zochitira izi.

• Opaleshoni ya Cryosurgery
• Opaleshoni yamagetsi
• Chithandizo cha laser
• Mitundu ya zokutira zapadera

Kodi mungakhale bwanji ndi thanzi labwino ndi matenda a WHIM?

Mukakhala ndi vuto losowa chonchi, muyenera kuganizira kwambiri za thanzi lanu.

• Zakudya zabwino: Zakudya zopatsa thanzi ndizofunikira kwambiri kuti chitetezo cha mthupi lanu chikhale champhamvu. Phatikizani ndiwo zamasamba, zipatso, tirigu wonse, nsomba, ndi nkhuku muzakudya zanu.
• Kuchita Masewera Olimbitsa Thupi: Kuchita masewera olimbitsa thupi kumathandiza kuti thupi likhale lamphamvu komanso kumalimbitsa chitetezo cha mthupi. Chitani zomwe mumakonda, monga masewera olimbitsa thupi, kuyenda, kapena kusambira, tsiku lililonse.
• Chitetezo ku matenda:
• Pewani malo odzaza anthu momwe mungathere.
• Sambani m'manja nthawi zambiri ndi sopo.
• Lankhulani ndi dokotala wanu ndipo sankhani katemera amene inu ndi banja lanu mukufunikira.Kambiranani makamaka za zinthu monga katemera wa HPV, katemera wa chibayo, ndi katemera wa chimfine wa pachaka.

Kuwonjezera pa dokotala wa banja lanu, mungafunike thandizo la madokotala osiyanasiyana, monga katswiri wa chitetezo cha mthupi, katswiri wa magazi, ndi katswiri wa khungu, kuti akuthandizeni.