Reka twige neza ku ndwara zidasanzwe zijyana na kanseri (Paraneoplastic Syndromes)!

Ese wigeze wumva umuntu urwaye kanseri agira ibimenyetso bidaterwa na kanseri ubwayo, ahubwo bigaterwa n'izindi ndwara? Ni nk'aho kanseri iri mu gice kimwe cy'umubiri, ariko ingaruka zayo zigakwirakwira no mu bindi bice. Ibyo ni byo twita (Paraneoplastic Syndromes) . Ibi bishobora kumvikana nk'ibigoye, ariko reka tuganire ku biri kuba. Ntutinye, ni ngombwa cyane kubimenya.

Indwara ya paraneoplastic ni iki?

Mu magambo make, iyo urwaye kanseri, tuyita Paraneoplastic Syndrome , ari na yo mpamvu hari ibindi bimenyetso bigaragara mu mubiri bidatewe n’uturemangingo twa kanseri. Tekereza, hari kanseri mu mubiri, ariko imisemburo cyangwa poroteyine zimwe na zimwe zituruka kuri yo zituma sisitemu imwe n’imwe mu mubiri itangira gukora mu buryo butandukanye. Cyangwa, rimwe na rimwe ubudahangarwa bwacu bw’umubiri , mu gihe bugerageza gusenya uturemangingo twa kanseri, bukibasira uturemangingo twiza mu buryo butari bwo. Ibi tubyita igisubizo cy’ubwiyongere bw’umubiri . Ibi bimenyetso bishobora no kubaho muri bene ibyo bihe.

Indwara za Paraneoplastic zishobora kugira ingaruka ku mikorere myinshi itandukanye y’umubiri. Urugero, uturemangingo tw’imitsi yawe, uturemangingo tw’imisemburo (uturemangingo dukora imisemburo), impyiko , amagufwa , ingingo , uruhu, n’amaraso byose bishobora kugira ingaruka.

Akenshi, ibimenyetso bya kimwe muri ibi (Paraneoplastic Syndromes) ni byo bimenyetso bya mbere bya kanseri. Kubwibyo, ni ngombwa cyane kubimenya.

Ni nde ushobora kwibasirwa n'iki kibazo cyane? (Ni nde uterwa n'indwara zo mu bwoko bwa paraneoplastic syndrome?)

Indwara za Paraneoplastic zikunze kugaragara cyane mu bantu bafite imyaka yo hagati n'abakuze, cyane cyane abafite indwara nka kanseri y'ibihaha , kanseri y'imitsi , kanseri y'intanga ngore , cyangwa kanseri y'ibere . Ibintu bimwe na bimwe bitera kanseri nabyo bishobora gutera izi ndwara.

Ibi bikunze kugaragara gute? (Ni gute indwara za paraneoplastic zikunze kugaragara?)

Indwara ya Paraneoplastic Syndromes igaragara hagati ya 8% na 20% by'abantu barwaye kanseri. Ibi bivuze ko atari abarwayi bose ba kanseri bayirwara, ariko ishobora kugira ingaruka ku mubare munini.

Ni izihe kanseri zifitanye isano na paraneoplastic syndromes?

Umuntu wese ufite ikibyimba cya kanseri (Paraneoplastic Syndrome)Nubwo kimwe muri byo gishobora kubaho, hari ubwoko butandukanye bwa kanseri bukunze kujyana n'izi ndwara:

• Kanseri y'ibere
• Kanseri y'igifu
• Leukemia
• Lymphoma
• Kanseri y'ibihaha (cyane cyane kanseri y'ibihaha y'uturemangingo duto)
• Kanseri y'intanga ngore
• Kanseri y'impyiko
• Kanseri ya porositate
• Kanseri y'impyiko
• Kanseri y'intanga

Ni iki gitera indwara zo mu bwoko bwa paraneoplastic syndrome?

Twamaze kuganira ku mpamvu ebyiri z'ingenzi zibitera.

1. Ibintu biva mu turemangingo twa kanseri: Hari kanseri zitanga imisemburo na poroteyine . Ibi bintu bituma ingingo zimwe na zimwe z'umubiri zigira imikorere idasanzwe. Iyo bitavuwe, bishobora no kwangiza ubuzima burundu.

2. Indwara zidakora neza: Ubudahangarwa bw'umubiri wacu buriho kugira ngo buturinde indwara. Ubu buryo bukora ibintu byitwa antibodies . Izi antibodies zimenya kandi zigasenya uturemangingo tudasanzwe, nk'uturemangingo twa kanseri. Ariko rimwe na rimwe, izi bimenyetso biravangwa maze antibodies zigatangira kwibasira uturemangingo tuzima. Ni bwo ibimenyetso bya (Paraneoplastic Syndrome) bigaragara.

Ni ibihe bimenyetso by'indwara zo mu bwoko bwa paraneoplastic syndrome?

Ibimenyetso bigaragara muri ibi bishobora gutandukana bitewe n'umuntu ku giti cye. Biterwa n'imiterere y'umubiri wafashwe. Igitangaje ni uko mu bantu barenga 60% , ibimenyetso by'iyi ndwara bigaragara mbere yuko kanseri imenyekana. Kubwibyo, iyo ibi bimenyetso bigaragaye hakiri kare, kanseri ishobora kumenyekana no kuvurwa hakiri kare. Icyo gihe amahirwe yo kugira icyo ikora ni menshi.

Ibimenyetso bisanzwe

Ibi ni bimwe mu bimenyetso bikunze kugaragara:

• Umuriro
• Kubura ubushake bwo kurya no kugabanya ibiro
• Kubira ibyuya nijoro

Iyo uturemangingo tw'imitsi twagize ingaruka

Niba uturemangingo tw’imitsi two hagati (ni ukuvuga ubwonko bwawe n’umugongo wawe) hamwe n’utwo mu mitsi yo mu gice cyo hagati (imitsi isohoka mu bwonko n’umugongo wawe) byagize ingaruka, ushobora kugira ibimenyetso nk'ibi:

• Kuzungera
• Kureba kabiri
• Ingorane zo kuvuga
• Gutakaza kwibuka
• Indwara z'igicuri ( igicuri )
• Intege nke z'imitsi
• Kugabanuka k'uburyo bwo kumva, kumva cyangwa guhuza ibintu
• Kubura ibyiyumvo mu maboko no mu maguru yawe

Tekereza umuntu urwaye kanseri y'ibihaha, ariko agahita atangira kwibagirwa, kuvuga nabi iyo avuga, kandi akagorwa no kugumana uburinganire bwe iyo agenda. Ni bwo abaganga bakeka ko iyi ari indwara ya (Paraneoplastic Syndrome) .

Iyo sisitemu y'imisemburo igize ingaruka

Niba sisitemu yawe y'imisemburo yaragize ingaruka, ushobora kugira ibimenyetso nk'ibi:

• Umunaniro ukabije
• Umuvuduko ukabije w'amaraso
• Intege nke z'imitsi
• Isesemi no kuruka
• Kongera ibiro mu buryo butunguranye nta mpamvu iyo ari yo yose

Iyo ingingo, amagufwa n'imitsi bigize ingaruka (ingingo, amagufwa n'imitsi - rubagimpande)

Niba izi sisitemu zigize ingaruka:

• Indwara nka rubagimpande
• Kubabara ingingo, kubyimba cyangwa gukomera

Iyo bigira ingaruka ku ruhu (Uruhu)

Hari igihe uruhu rushobora no kwibasirwa:

• Kuryarya
• Gusukura amazi
• Uruhu rwinshi
• Uruhu rudafite ingaruka mbi (rutari urwa kanseri)

Ni ubuhe bwoko bw'indwara za paraneoplastic?

Hari ubwoko butandukanye bwa Paraneoplastic Syndromes . Bushyirwa mu byiciro hakurikijwe uburyo bugira ingaruka kuri buri ngirabuzimafatizo.

Indwara zo mu bwonko ziterwa na paraneoplastic syndrome

Ingero zimwe na zimwe:

• `(Kugabanuka k'ubwonko)`: Ibi ni ukwangirika k'ubwonko, bigira ingaruka ku bintu nko kuringaniza no kugenda.
• Dysautonomia: Igira ingaruka ku mikorere y'imitsi ikora ku buryo bworoshye.
• Encephalitis: Kubyimba ubwonko.
• Encephalomyelitis: Kubyimba ubwonko n'umugongo.
• Lambert-Eaton myasthenic syndrome (LEMS): Itera intege nke z'imitsi.
• Myasthenia gravis (MG): Iyi ni indi ndwara itera intege nke z'imitsi.
• Mielopathy: Indwara zigira ingaruka ku mugongo.
• Neuromyotoniya: Gukora imitsi buri gihe.
• `(Opsoclonus-myoclonus syndrome)`: Ingendo zitari zisanzwe z'amaso n'imitsi.
• `(Imitsi yo mu bwonko (imitsi yo mu bwonko)`: Kwangirika kw'imitsi yo mu bwonko.
• `(Stiff-person syndrome)`: Kugorana kw'imitsi no kubabara mu nda.

Indwara za paraneoplastic mu mikorere y'imisemburo

Ingero:

• `(Indwara ya Cushing): Indwara iterwa n'ubwiyongere bw'imisemburo ya cortisol.
• Hypercalcemia: Ubwiyongere bwa kalisiyumu mu maraso.
• `(Indwara yo Kubika Imisemburo Idakwiye Irwanya Imyanda (SIADH))`: Indwara ituma amazi aguma mu mubiri.

Indwara ya paraneoplastic ya rubagimpande

(bigira ingaruka ku ngingo, amagufwa, imitsi n'ingingo zihuza)

Ingero:

• `(Eosinophilic fasciitis)`
• `(Erythromelalgia)`
• `(Hypertrophic osteoarthropathy)`
• `(Palmar fasciitis)`
• `(Paraneoplastic polyarthritis)`

Indwara zo mu maraso ziterwa n'indwara ya paraneoplastic

Ingero:

• `(Paraneoplastic erythrocytosis)`: Ukwiyongera kw'uturemangingo dutukura tw'amaraso.
• `(Paraneoplastic thrombocytosis)`: Ubwiyongere bw'ibinure mu maraso.

Indwara zo mu bwoko bwa paraneoplastic mu ruhu

Ingero:

• Akanthosi nigricans: Uduce twijimye kandi twinshi ku ruhu.
• Dermatomyositis: Kubyimba uruhu n'imitsi.
• Leukocytoclastic vasculitis: Kubyimba imitsi mito y'amaraso.
• `(Paraneoplastic pemphigus)`: Indwara itera uduheri ku ruhu.
• `(Syndrome nziza)`: Umuriro n'ibisebe by'uruhu bibabaza.

Indwara zo mu mpyiko ziterwa n'indwara ya paraneoplastic

Paraneoplastic glomerulonephritis ni indwara ifata impyiko.

Ni gute indwara za paraneoplastic zipimwa?

Muganga wawe azasuzuma iyi ndwara akubaza amateka y'ubuzima bwawe, agukorere isuzuma ry'umubiri, kandi agukorere n'ibindi bipimo byinshi.

• Isuzuma ry’imitsi: Kubera ko iyi ndwara ikunze kugira ingaruka ku mikorere y’ubwonko, muganga wawe azagusaba gukora ibintu bimwe na bimwe kugira ngo arebe uko ubwonko bwawe n’imitsi bikora. Azagusuzuma niba hari impinduka mu mbaraga zawe, kwibuka kwawe, no guhuza ibikorwa byawe.
• Ibizamini byo gupima: Ibizamini nka CT scans , MRIs , na ultrasounds bishobora gukoreshwa kugira ngo harebwe niba hari ikibyimba gitera ibimenyetso.
• Gupima amaraso: Gupima amaraso bishobora kugaragaza ibintu bishobora gutera gukeka kanseri. Bishobora kandi gusuzuma uturemangingo tw’umubiri dufitanye isano na paraneoplastic syndromes . Ibi bizamini bishobora kandi kugaragaza niba ibimenyetso biterwa n’izindi mpamvu, nko kwandura cyangwa imisemburo idahwitse.
• Gutobora uruti rw'umugongo/gutobora uruhu rw'umugongo: Hari igihe, amazi yo mu bwonko (CSF) apimwa kugira ngo harebwe niba hari uturemangingo twibasira uturemangingo tuzima. Ibi bisaba gushyira urushinge ruto mu mugongo wo hasi no gufata icyitegererezo cy'amazi. Hanyuma birasuzumwa.

Izi ndwara zivurwa zite? (Ni gute indwara za paraneoplastic zivurwa cyangwa zivurwa?)

Igikuru ni ukuvura kanseri itera ibimenyetso byawe. Ariko nanone, ugenzura ibimenyetso byawe kugira ngo ugabanye kwangirika kw'ingingo cyangwa sisitemu z'umubiri wawe.

Bumwe mu buryo bwo kuvura indwara za Paraneoplastic :

• Corticosteroids:Imiti nka `(Cortisone)` cyangwa `(prednisone)`. Iyi ikora mu kugabanya ububyimbirwe (kubyimba) mu mubiri.
• Guhagarika ubudahangarwa bw'umubiri: Imiti igabanya uburyo ubudahangarwa bw'umubiri wawe bwitwara. Muganga wawe azaguha imiti ishingiye ku bwoko bwa paraneoplastic syndrome ufite.
• Intravenous immunoglobulin (IVIG): Ubu buryo bukora mu gusenya antibody zangiza. Muri ibi, antibody nzima zitangwa nk'urushinge, rusenya antibody zangiza.
• Plasmapheresis: Ibi bikubiyemo gukura plasma (igice cy'amazi mu maraso) mu maraso kugira ngo bigabanye ingano y'uturemangingo tw'umubiri, tuba muri iyi plasma kandi dushobora kwangiza ingirabuzima fatizo.
• Ubuvuzi bw'umubiri n'ubwo kuvuga: Ibi bikubiyemo imyitozo ngororamubiri kugira ngo kunoze ibikorwa nko kuvuga no kwimuka. Ushobora gukenera ubu buvuzi niba ufite indwara ya paraneoplastic ifitanye isano n'imitsi.

Ni iki nakwitega mu gihe mfite indwara ya paraneoplastic?

Uko kanseri yawe ihagaze biterwa ahanini n'aho igeze. Hari igihe ibimenyetso biterwa n'iyi ndwara bishobora kuba byoroheje kandi by'igihe gito. Hari n'igihe ibimenyetso bishobora kuba bikomeye kandi bigasaba ko ubyitabwaho igihe kirekire.

Vugana na muganga wawe uburyo kanseri yawe ihagaze n'uko ubyitwaramo ku miti bizagufasha gukira.

Ni izihe ngorane zifitanye isano n'indwara za paraneoplastic?

Ibi bishobora gutera ingorane zitandukanye. Zimwe zishobora kuba ntoya, izindi zishobora kuba zikomeye ndetse zikanashyira ubuzima mu kaga mu gihe zitavuwe. Muganga wawe azagusobanurira ingorane zishobora kubaho n'uburyo bwo kuvura.

Ni ryari nkwiye guhamagara muganga ku bijyanye n'indwara za paraneoplastic?

Niba ugaragaje ibimenyetso bya paraneoplastic syndrome nta mpamvu igaragara, gana muganga. Cyane cyane niba waravuwe kanseri mu myaka itanu ishize kandi ukaba urimo kubona ibi bimenyetso, ni byiza kongera kwipimisha. Ibi bizafasha muganga wawe kumenya niba kanseri yagarutse.

Ni ibihe bibazo ngomba kubaza muganga wanjye?

Ibibazo bimwe na bimwe ushobora kubaza muganga wawe:

• Ni iyihe mpamvu y'ibimenyetso byanjye?
• Ni gute indwara yanjye (Paraneoplastic Syndrome) igira ingaruka ku gahunda yanjye yo kuvura kanseri?
• Ni ubuhe buryo bwo kuvura mfite?
• IbyanjyeNi gute Paraneoplastic Syndrome igira ingaruka ku gukira kwanjye?
• Ese ibimenyetso byanjye bizagenda neza nyuma yo kuvurwa kanseri?
• Nigute wakwifata ibimenyetso mu gihe gito? Nigute wakwifata ibimenyetso mu gihe kirekire?

Amaherezo, ubutumwa bwo kujyana mu rugo

Ibibyimba bya kanseri bishobora gutera impinduka zitunguranye mu mubiri. Hari igihe bishobora no kuba birimo ibimenyetso bya paraneoplastic syndrome . Kubera ko hari ubwoko bwinshi bw'izi ndwara kandi ibimenyetso bikaba bitandukanye, bishobora gufata igihe kugira ngo muganga wawe amenye ko ibimenyetso byawe bifitanye isano na kanseri. Ariko, iyo ibimenyetso byemejwe, ashobora kuvura ibimenyetso ndetse n'icya ngombwa, kanseri y'ishingiro .

Uburyo bwiza bwo kurwanya Paraneoplastic Syndrome ni ukubona uburyo bwiza bwo kuvura kanseri. Rero, ntukirengagize ibimenyetso. Niba ufite gushidikanya, gana muganga vuba bishoboka. Icyo gihe ni bwo twese dushobora gukomeza kugira ubuzima bwiza.

Indwara za Paraneoplastic , kanseri, ibimenyetso, uturemangingo tw'imitsi, uturemangingo tw'imisemburo, uturemangingo tw'ubudahangarwa bw'umubiri, kuvura kanseri