Biragoye gusobanura mu magambo uko wumva iyo umenye ko wowe cyangwa umuntu ukunda afite kanseri. Ni ibisanzwe kumva ufite ubwoba kandi ushishikajwe no kumenya uburyo bushya bwo kuvura, nka PRRT, ijambo ritamenyerewe. Ariko ntugahangayike. Nubwo iyi ari ingingo igoye, uyu munsi turaganira ku cyo PRRT ari cyo, icyo ikora, n'ibyiza n'ibibi byayo, mu buryo bworoshye cyane ushobora gusobanukirwa.
PRRT bisobanura iki mu buryo bworoshye?
Muri make, PRRT ni uburyo bugezweho bwo kuvura bugamije kurwanya, gushakisha no gusenya uturemangingo twa kanseri, nk'uko "missile iyobowe" . Ikoreshwa by'umwihariko mu kuvura ubwoko bwa kanseri yitwa `Neuroendocrine Tumors (NETs).'
Umwihariko w'ubu buryo bwo kuvura ni uko ibintu bitanga imirasire (radioactivity) bivamo bijya mu tunyangingo twa kanseri bikatwica. Kubwibyo, kwangirika kw'utunyangingo tuzima ni bike cyane ugereranyije no kuvurwa buri gihe hakoreshejwe imirasire.
Ubu buvuzi bukora bute imbere mu mubiri?
Kugira ngo tubisobanukirwe neza, reka dukoreshe urugero rworoshye. Tekereza ko uturemangingo twa kanseri yawe ari inzugi zifite 'imyobo myinshi' yihariye ('receptors'). Buri rugi rujya gusa n'urufunguzo rufite imiterere runaka.
Uyu muti witwa PRRT, ukorwa hakoreshejwe uburyo bubiri buvanze:
1. Urufunguzo: Uru ni poroteyine. Uru rufunguzo rushobora kwinjira gusa mu "mwobo w'urufunguzo" rw'uturemangingo twa kanseri. Ntirujya mu turemangingo tuzima.
2. Umugenzi ukoresha imirasire: Uru rufunguzo rufite ikintu gito cyane gikoresha imirasire (`radionuclide`) gifatanye na rwo.
Rero, iyo uhaye umubiri wawe uyu muti, uru "rufunguzo" runyura mu mubiri wose, rusangamo "imyobo y'urufunguzo" mu turemangingo twa kanseri, rukayifata. Hanyuma, "umugenzi ukoresha imirasire" ku rufunguzo yinjira mu turemangingo twa kanseri, yangiza ADN y'iyo selile, kandi ikangiza selile imbere.
Ubu buryo bwemerera kwangiza uturemangingo twa kanseri gusa, hatabayeho kwangiza cyane uturemangingo tuzima. Iyi ni yo nyungu ikomeye y'ubu buryo bwo kuvura.
Umuti wa PRRT ukoreshwa cyane muri iki gihe ni `lutetium Lu 177 dotatate (LUTATHERA®)`.
Ni nde usabwa kuvura PRRT?
Ubu buryo bwo kuvura ntibukwiriye abarwayi bose ba kanseri. Muri iki gihe, bugirwa inama cyane cyane kuri kanseri yitwa `gastroenteropancreatic NETs`, ari zo kanseri zo mu nzira y'igogora (amara, igifu, rectum) na pancreas. Hari ibihe byinshi ubu buryo bushobora kukubera bwiza.
| Imiterere | Ibisobanuro |
|---|---|
| Ntibikwiriye kubagwa | Iyo kanseri yakwirakwiriye mu bice byinshi by'umubiri, kubagwa byonyine ntibishoboka ko bizatanga ubuvuzi bwuzuye. Abantu benshi bafite NET bashobora kuba barayikwirakwije igihe bayimenye. |
| Ubundi buryo bwo kuvura ntabwo bwagenze neza | Mu gihe kubagwa bidashoboka, ibintu nk'ubuvuzi bw'imisemburo biratangwa. Ariko rimwe na rimwe, ubwo buryo bwo kuvura butuma uturemangingo twa kanseri dukomeza gukura mu buryo butunguranye. Kuri abo bantu, PRRT ni amahitamo meza. |
| Uturemangingo twa kanseri dufite uwo "mwobo w'ingenzi" | Iki ni cyo kintu cy'ingenzi cyane. Kugira ngo umuti wa PRRT ugere ku 'kiyiko' kandi uhuze, hagomba kuba hari 'imyobo' yitwa somatostatin receptors ku buso bw'uturemangingo twa kanseri. Muganga wawe azakora isuzuma ryihariye, nka octreotide scan cyangwa PET scan , kugira ngo arebe niba uturemangingo twa kanseri dufite ibi. |
Ni iki kibaho mbere no mu gihe cyo kuvurwa?
Mbere yo kuvurwa
Niba ufata indi miti ya NET (cyane cyane somatostatin analogues), muganga wawe ashobora kukugira inama yo guhagarika kuyifata ibyumweru bike mbere ya PRRT. Muganga wawe ashobora kandi gukora ibizamini by'amaraso icyumweru kimwe mbere y'uko uvurwa kugira ngo arebe imikorere y'impyiko zawe n'umubare w'uturemangingo tw'amaraso kugira ngo arebe neza ko umubiri wawe umeze neza kugira ngo uhabwe ubuvuzi.
Ku munsi wo kuvurwa
Ubu buvuzi busanzwe butangwa buri mezi abiri mu gihe cy'amezi 4 mu gihe cy'amezi 8. Ubu buvuzi bukorerwa hanze y'ibitaro, utiriwe urara mu bitaro. Ubu buvuzi bwose bumara amasaha agera kuri 5-6.
- Ubwa mbere, umuyoboro muto (cannula) winjizwa mu mutsi uri mu kuboko kwawe hanyuma hagakorwa umurongo w'amazi.
- Hasigaye isaha imwe mbere y'uko ubuvuzi butangira, hatangwa imiti yo kwirinda isesemi no kuruka.
- Hanyuma, uzahabwa umuti wa saline urimo aside amine kugira ngo urinde impyiko zawe mu gihe cy'amasaha agera kuri 4. Ibi ni ingenzi cyane.
- Nyuma y'iminota 30 aside amine zitangiye gutangwa, umuti wa PRRT ushyirwa mu mubiri binyuze mu munyu mu gihe cy'iminota 30-45.
- Iyo umunyu wose umaze gutangwa, umuyoboro uri mu kuboko urakurwaho.
Umunsi ukurikira uwo muti, uzongera gupimwa kugira ngo urebe aho umuti wa radiyo wageze mu mubiri wawe, cyane cyane aho ibibyimba bya kanseri biri.
Ingaruka mbi n'ingaruka mbi ni izihe?
Nkuko bigenda ku buvuzi ubwo aribwo bwose, hashobora kubaho ingaruka zimwe na zimwe.
Ingaruka mbi zikunze kugaragara:
Ingaruka mbi zikunze kugaragara ni isesemi no kuruka , ariko ibi bishobora kugenzurwa ahanini no kuvurwa hakiri kare.
Izindi ngorane zishobora kubaho:
- Ingaruka iyo ari yo yose ku mikorere y'impyiko cyangwa umwijima.
- Kugabanuka k'umubare w'uturemangingo tw'amaraso (uturemangingo tw'amaraso twera, uturemangingo dutukura, uduce duto tw'amaraso). Ibi bishobora gutera ingorane zo guhumeka, kwandura indwara nyinshi, ndetse n'ibyago byo kuva amaraso cyangwa gukomereka.
- Ni gake cyane, hari ibyago bike cyane byo kurwara izindi kanseri z'amaraso nka myelodysplastic syndrome cyangwa leukemia.
Muganga wawe azakurikirana urugero rw'amaraso yawe buri gihe mu gihe cyose cy'ubuvuzi bwawe. Iyo habayeho ikibazo, ashobora gufata icyemezo cyo guhindura ingano cyangwa guhagarika imiti yawe.
Ikibazo gikomeye cyane gisaba kwitabwaho byihuse!
Indwara ya kanseri ni indwara idasanzwe ariko ishobora gushyira ubuzima mu kaga ishobora kubaho muri ubu buvuzi. Iterwa no kurekura imisemburo myinshi iva mu turemangingo twa kanseri mu maraso mu buryo butunguranye. Ibimenyetso bishobora kugaragara mu masaha 48 ya mbere uhereye igihe wahawe ubuvuzi.
Niba ufite kimwe muri ibi bimenyetso, jya ku bitaro bikuru byita ku bibazo byihutirwa (ETU) cyangwa uhamagare 1990:
* Kugorwa no guhumeka
* Gutukura mu maso cyangwa mu ijosi, kumva ushyushye cyangwa ushyushye mu mubiri (Gushyuha)
* Kugabanuka k'umuvuduko w'amaraso mu buryo butunguranye (kumva umeze nk'uzunguza)
* Umutima utera cyane
* Impiswi ikomeye
Ubuzima bwa buri munsi nyuma yo kuvurwa
Abantu benshi bihanganira ubu buvuzi neza kandi bagakira vuba.
Imirasire n'umutekano:
Ubu buvuzi bukoresha imirasire mike cyane. Iyi mirasire izava mu mubiri wawe mu nkari no mu mwanda wawe mu minsi mike iri imbere. Muri iki gihe, muganga wawe azaguha amabwiriza yo kwirinda ko abandi bahura n'imirasire.
- Ni ngombwa cyane cyane kwirinda iminsi mike abagore batwite n'abana bato .
- Karaba intoki zawe neza n'isabune nyuma yo kuva mu bwiherero.
Ingendo:
Hashobora kubaho imirasire mike cyane mu mubiri wawe mu gihe cy'amezi atatu nyuma yo kuvurwa. Ibi bishobora gutera ibyuma bipima imirasire ku bibuga by'indege cyangwa ku mipaka. Kubwibyo, buri gihe komeza ubike ikarita yihariye uhabwa n'ibitaro hamwe n'amakuru ajyanye n'ubuvuzi bwawe. Ibi ni ingenzi cyane kugira ngo wirinde ingorane iyo ari yo yose mu rugendo.
Ubutumwa bwo kujyana mu rugo
- PRRT ni uburyo bugezweho bwo kuvura butanga imirasire yibasira uturemangingo twa kanseri. Bukoreshwa cyane cyane ku tumori two mu maraso (Neuroendocrine Tumors).
- Nubwo ubu buvuzi butari buvura kanseri burundu, bufasha kugabanya cyangwa guhagarika gukura kwa kanseri, kugabanya ibimenyetso, no kunoza ubuzima binyuze mu kongera igihe cyo kubaho.
- Mu minsi mike nyuma yo kuvurwa, kurikiza amabwiriza yatanzwe kugira ngo urinde abandi imirasire (cyane cyane kwirinda abana bato n'abagore batwite).
- Menya ibimenyetso by'indwara ya kanseri (kugorwa no guhumeka, guhumeka amazi, impiswi ikabije, gutera k'umutima kwiyongera). Niba ubonye kimwe muri ibi bimenyetso, jya kwa muganga wita ku buzima bw'abantu .
- Ntugatinye kuvugana na muganga wawe ku ngaruka cyangwa ibibazo ushobora guhura na byo.
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