Ese umwana wawe ahora arwara umuriro? Ese byaba biterwa na SAIDs (indwara zifata umubiri)?

Ese umwana wawe ahora agira umuriro muri iyi minsi? Iyo utekereje ko wakize, urongera ukabyimba? Hari igihe impamvu y'ibi ishobora kuba atari virusi cyangwa bagiteri bisanzwe. Uyu munsi tugiye kuvuga ku ndwara igoye gato, ariko ni ingenzi cyane kuyimenya. Iyi ndwara yitwa SAIDs, bisobanura indwara ziterwa no kwibasira umubiri . Mu bihe byashize, iyi ndwara yitwaga `(Periodic Fever Syndromes)` cyangwa `(Recurrent Fever Syndromes)`.

SAIDs ni iki? Reka tubisobanukirwe mu buryo bworoshye.

Muri make, SAID ni itsinda ry'indwara ziterwa n'ikibazo cy'imikorere mibi cyangwa ikibazo cy'ubuyobozi mu budahangarwa bw'umubiri wacu . Niyo mpamvu umwana ashobora kurwara umuriro kenshi nubwo nta bwandu afite (nk'agakoko cyangwa bagiteri).

Igikomeye cyane ni uko izi ndwara zitwa SAID zitagomba kwitiranywa na `(Indwara ziterwa no kwirwanaho)` (urugero `(Rheumatoid Arthritis)` cyangwa `(Lupus)` ushobora kuba warumvise. Mu ndwara `(Autoimmune)`, bitewe n'ikosa runaka mu `(adaptive unitness system)` y'umubiri wacu, ubwo buryo bwibasiye uturemangingo twabwo tuzima. Ariko muri SAID, hari ikindi kintu kibaho.

SAIDs ni indwara zikunze kugaragara cyane kurusha indwara ziterwa n’ubwiyongere bw’umubiri. Akenshi ziba ari iz’uruhererekane kandi ziterwa n’impinduka mu miterere y’uturemangingo .

Ubusanzwe, ariko si buri gihe, ibimenyetso bya SAID bitangira umwana akiri muto cyane, haba mu ruhinja cyangwa umwana muto . Umwana wawe ashobora kugira "ibihe" by'umuriro n'ibindi bimenyetso hamwe n'iyi ndwara. Hagati y'ibi bihe, umwana wawe ashobora kuba nta bimenyetso na gato afite. Nubwo nta muti wa SAID uhari , akenshi hariho uburyo bwo kuvura bufasha mu kugenzura ibimenyetso by'umwana wawe.

Ni ubuhe bwoko bw'ingenzi bwa SAIDs?

Abashakashatsi bavumbuye ubwoko bugera kuri 60 bwa SAID, kandi buracyavumburwa bushya. Dore bumwe mu bwoko bukunze kugaragara bwa SAID:

• Indwara y'umuriro yo mu bwoko bwa Mediterane (FMF): Iyi ni yo ndwara ikunze kugaragara mu ndwara zivuka mu buryo bw'uturemangingo, zigaruka kenshi. Ishobora gutera kubyimba kubabaza mu nda, mu gituza no mu ngingo ku bana.
• Umuriro uhoraho, aphthous-stomatitis, pharyngitis, adenitis (PFAPA): Ibi bikunze gutangira ku bana bato mbere y'imyaka 4. Hari igihe, iyo ndwara ishobora kumera neza ubwayo nyuma y'imyaka 10.
• Indwara y’ingirabuzimafatizo iterwa n’ingirabuzimafatizo (TRAPS): Ibi bishobora kubaho mu bwana, mu gihe cy’ingimbi cyangwa mu bwana.
• Ubukene bwa Mevalonate kinase (MKD): Mbere yitwaga ``Hyper-IgD syndrome'', ibi bikunze gutangira umwana atarageza ku mwaka umwe.
• Indwara ziterwa no kubyimbirwa mu mubiri ziterwa na NLRP3:Ibi byari byitwaga mbere `(Cryopyrin-associated periodic syndromes - CAPS)`. Hari izindi nkomoko eshatu muri ibi.
• Indwara ya Still y’abantu bakuru (AOSD): Nk’uko izina ribigaragaza, iyi ni indwara iterwa n’indwara y’abana bato yitwa "Systemic Juvenile Idiopathic Arthritis (JIA)" iterwa n’abantu bakuru.
• Indwara ya granulomatous ifitanye isano na NOD-2 (Blau syndrome): Ibi bikunze gutangira mbere y'imyaka 4. Bigira ingaruka cyane cyane ku ruhu rw'umwana, amaso n'ingingo.

Ni ibihe bimenyetso bya SAID?

Ibimenyetso bya SAID bikunze gutangirira mu bwana. Ikimenyetso nyamukuru kandi gikunze kugaragara ni umuriro uhoraho . Mu gihe cy'umuriro, abantu bashobora kuba bazima kandi nta bimenyetso bagaragaza. Ariko, hashobora kubaho ibindi bimenyetso byihariye kuri buri bwoko bwa SAID. Reka turebe ibyo ari byo:

• FMF: Ibi bishobora gutera kubyimba no kubabara cyane mu nda y'umwana, mu gituza no mu ngingo . Hashobora kandi kubaho uduheri ku maguru yo hasi cyangwa ku tuguru.
• PFAPA: Ibi bishobora gutera ububabare mu muhogo, ibisebe mu kanwa, no kubyimba imitsi mu ijosi . Urugero, niba umwana wawe agaragaza ibimenyetso nko guhora arwaye tonsillitis n'ibisebe mu kanwa, bishobora kuba PFAPA.
• IMITEGO: Ibi bishobora gutera ubukonje n'ububabare bw'imitsi mu gituza/umubiri no mu maboko . Bishobora kandi gutera uduheri dutukura dukomeretsa dutangirira ku maboko no ku maguru tugakwirakwira mu mubiri wose.
• MKD: Ibi bishobora gutera ibimenyetso nko gukonja, kuribwa umutwe, kubabara mu gifu, kubura ubushake bwo kurya, n'ibimenyetso bisa n'ibicurane .
• Indwara za NLRP3: Iyi ndwara ishobora gutera uduheri ku ruhu, kuribwa umutwe, kurwaragurika, kubabara ingingo, no kurwara amaso/amaso y’umutuku .
• AOSD: Iyi ni indwara irangwa no kubabara uruhu, kubabara ingingo, no kubabara imitsi . Hari abantu bashobora no kubabara mu muhogo, kubabara mu nda, umunaniro, no kurwaragurika.
• Indwara ya Blau: Ibi bishobora gutera udusebe ku ruhu rw'umwana wawe mu maboko, ku maguru, cyangwa hagati mu kibuno . Bishobora kandi gutera ububabare mu ngingo no kubabara amaso .

Ni izihe mpamvu zitera SAIDs?

SAID nyinshi ni indwara zikomoka ku maraso . Ni ukuvuga ko impinduka runaka (variant) muri gene runaka ari yo itera buri syndrome. Tekereza ko umubiri wacu ufite amabwiriza (genes) atubwira uko twakora buri gikorwa, bityo niba inyuguti imwe muri icyo gitabo itari yo, ishobora gutuma akazi gasigaye kagenda nabi.

Dore ubwoko bw'ingenzi bwa SAID n'uturemangingo dufitanye isano nabyo:

• FMF:Ingirabuzimafatizo `MEFV` niyo itanga amabwiriza y'uko poroteyine `(pyrin)` ikorwa.
• PFAPA: Impamvu nyayo y'ibi ntiramenyekana .
• IMITEGO: Ingirabuzimafatizo `TNFRSF1A`. Ibi biyobora ikorwa rya poroteyine yitwa `(receptor y'ingirabuzimafatizo ya tumor necrosis - TNFR)`.
• MDK: Ingirabuzimafatizo yitwa `MVK`. Ibi biyobora ikorwa rya poroteyine yitwa `(mevalonic kinase)`.
• Indwara za NLRP3: Ingirabuzimafatizo `NLRP3`. Ibi biyobora ikorwa rya poroteyine yitwa `(cryopyrin)`.
• AOSD: Impamvu nyayo y'ibi ntiraboneka .
• Blau syndrome: Gene `NOD2`. Ibi biyobora ikorwa rya poroteyine yitwa `(NOD2)`.

Ni ngombwa kumva ko iyo ibi biterwa n'ibintu bigize imiterere y'umubiri, atari ikosa ry'ababyeyi. Ibi ni ibintu bigoye cyane mu miterere y'umubiri.

Ingorane ziterwa na SAIDs

Ni ingenzi cyane kubona ubuvuzi bukwiye kuri izi ndwara. Kuko, iyo ububyimbirwe bukomeje mu mubiri, bishobora gutera indwara yitwa `(Amyloidosis). `(Amyloidosis)` ni poroteyine iba mu mpyiko . Ibi bishobora kwangiza impyiko burundu . Kubwibyo, niba hari ibimenyetso, ni ngombwa gushaka inama kwa muganga vuba.

Ni gute SAID zimenyekana?

Mu by’ukuri, gusuzuma indwara za SAID bishobora kugorana gato kuko ibimenyetso bishobora gusa n’iby’izindi ndwara zikomeye, nka lupus cyangwa lymphoma. Kubwibyo, ni ngombwa kubonana na muganga ufite amahugurwa yihariye mu ndwara ziterwa n’ububyimbirwe (umuganga w’indwara zo mu bwonko) kugira ngo amenye neza kandi acunge neza ikibazo cy’umwana wawe.

Umuganga w’indwara z’imitsi y’umwana wawe azakoresha ibintu byinshi kugira ngo amenye indwara za SAID. Azabaza ibimenyetso by’umwana wawe ndetse niba hari umuntu wo mu muryango wawe wigeze kugira izi ndwara (amateka y’umuryango). Muganga ashobora gukeka ko umwana wawe afite indwara y’umuriro w’igihe runaka niba:

• Niba ukunze kugira umuriro
• Niba hari umuntu mu muryango ufite amateka yo kurwara umuriro nk'uyu rimwe na rimwe
• Niba uri mu itsinda ry'abantu bakunze kugira ibyo bicurane

Ni ibihe bizamini bikoreshwa?

Muganga wawe ashobora kukugira inama yo gupima indwara nyinshi kugira ngo yemeze ko ufite ikibazo. Ibi bishobora kuba birimo:

• Ibizamini byo muri laboratwari: Ibizamini nka `(poroteyine ya C-reactive - CRP)` na `(Umubare wuzuye w'amaraso - CBC)` bishobora gusuzuma ububyimbirwe mu mubiri. Ibi bizamini biba `(byagaragaje)` iyo hari umuriro, kandi bigasubira ku gaciro kabyo iyo umuriro ushize.
• Isuzuma ry'inkari:Ikizamini cya poroteyine mu nkari gishobora gukorwa kugira ngo harebwe niba poroteyine nyinshi mu nkari. Muri MKD, ikizamini cy'inkari cya aside organic kizagaragaza urugero rwinshi rwa aside mevalonic.
• Gupima imiterere y’uturemangingo: Ibi bishobora kugenzura ubwoko bw’uturemangingo. Ariko, bamwe mu bana bafite SAID bashobora kutabona ubwoko bw’uturemangingo. Kubwibyo, nubwo ibisubizo by’ibizamini byaba ari ``negative``, birashoboka ko SAID yaba ari ntaho ihuriye.

Indwara za SAID zivurwa zite?

Uburyo bwo kuvura indwara za SAID butandukana bitewe n'ubwoko n'uburemere bw'indwara . Nubwo izi ndwara zidashobora gukira burundu, ibimenyetso by'umwana bishobora kugenzurwa neza hakoreshejwe imiti . Urugero, niba umwana wawe arwaye ibicurane inshuro nke mu mwaka, imiti igabanya ububabare n'imiti igabanya ububabare (NSAIDs) ishobora kugenzura ibimenyetso. Ariko, iyo indwara ikomeye cyane, muganga ashobora kuguha ubundi buryo bwo kuvura.

Dore bumwe mu buryo bwo kuvura:

• FMF: Ibi bishobora kuvurwa n'umuti witwa `(Colchicine)` kugira ngo ugabanye ububyimbirwe. Niba udashobora gufata `(Colchicine)`, ushobora kugerageza ubwoko bwa `(Biologic)` bw'umuti witwa `(Canakinumab)`.
• PFAPA: Kurwara kwa PFAPA bishobora kugabanuka hakoreshejwe imiti ya steroid (akenshi yitwa prednisone). Hari abana bashoboye kugenzura ibimenyetso byabo bakoresheje cimetidine, umuti ukoreshwa mu kuvura ibisebe byo mu gifu.
• IMIGOZI: Umuti `(Canakinumab)` ufasha cyane TRAPS. Nanone, imiti igabanya ububabare nka `(Glucocorticoids)` ishobora no kugabanya ibimenyetso.
• MKD: `(Canakinumab)` ni amahitamo meza yo kuvura MKD. Gukoresha `(NSAIDs)` cyangwa `(Steroids)` mu gihe cy'umuriro nabyo bishobora kuba ingirakamaro.
• Indwara za NLRP3: Izindi miti igabanya ubukana bw'umubiri nka Canakinumab na Rilonacept, Anakinra, zikora neza mu kuvura indwara za NLRP3.
• AOSD: Ubwoko butandukanye bw'imiti igabanya ububyimbirwe bukoreshwa kuri AOSD. Iyi miti irimo `(Steroids)`, `(Imiti igabanya indwara igabanya rubagimpande - DMARDs)`, na `(Biologics)`.
• Indwara ya Blau: Bitewe n'ibimenyetso by'umwana, imiti igabanya ubudahangarwa bw'umubiri, imiti igabanya ubukana bw'indwara ya tumor necrosis factor (TNF), cyangwa imiti ikoreshwa mu maso ishobora kugeragezwa.

Ese indwara ya SAID irushaho kuba nziza ubwayo?

Hari indwara za SAID zishobora kumara ubuzima bwose . Hari n'izindi zishobora kumara imyaka mike kandi zigakira uko umuntu agenda akura. Nubwo hari indwara zibaho ubuzima bwose, inshuro nyinshi umuriro utangira kwiyongera uko igihe kigenda gihita kandi ibimenyetso bikagabanuka . Muganga wawe ashobora kuguha ibisobanuro birambuye ku ndwara yihariye y'umwana wawe.

Kwita ku mwana urwaye SAID bishobora kugorana. Wenda nawe ubwawe wigeze ubivuga, ariko ushobora gukoresha ibyakubayeho kugira ngo ufashe umwana wawe kwita ku bana no kumufasha guhangana n'iki kibazo cy'ubuzima bwe bwose.

Igikuru ni ukugana abaganga b'inzobere bazi neza imiterere y'indwara za SAID. Bashobora kugufasha mu gucunga ibimenyetso by'umwana wawe no kumufasha kugira ubuzima bwiza bushoboka mu bwana bwe.

Ibintu by'ingenzi cyane ugomba kwibuka (Ubutumwa bwo kujyana mu rugo)

Sawa, reka tuvuge muri make bimwe mu bintu ugomba kwibuka mu byo twavuze.

• Niba umwana wawe afite umuriro ukabije kandi udasobanutse , ganira na muganga wawe kuri ibyo. Bishobora kuba ikimenyetso cya SAID.
• SAID ni ikibazo cy’ubudahangarwa bw’umubiri karemano , si indwara isanzwe yandura.
• Izi zitandukanye n'indwara za "Autoimmune" .
• Akenshi, ibi biterwa n'ibintu bigize imiterere y'umubiri .
• Ni ngombwa kubonana na muganga w’indwara za rubagimpande kugira ngo amenye neza indwara.
• Kuvura bishobora kugenzura ibimenyetso neza .
• Kuvura hakiri kare ni ngombwa kugira ngo hirindwe kwangirika kw'impyiko.

Niba ufite ibindi bibazo kuri ibi, ntutinye kubaza muganga w'umuryango wawe cyangwa muganga w'abana. Bazagufasha kurushaho.

SAIDs , umuriro ukomoka ku rubyaro, umuriro ukunze kugaragara, umuriro mu bana, ubudahangarwa bw'umubiri, indwara zikomoka ku ngirabuzimafatizo, inzobere mu ndwara za rubagimpande