Zvese nezve ACTH Stimulation Test, iyo inoyera mahormone emuviri wako!

Dzimwe nguva kana zvimwe zvinhu mumuviri wedu zvikasashanda zvakanaka, tinogona kuva nematambudziko akasiyana-siyana ehutano, handiti? Kunyanya kana paine kusawirirana mumahormone emuviri wedu, zvinogona kukanganisa zvikuru. Muchiitiko chakadaro, chiremba wako anogona kukukurudzira kuti uite bvunzo yakakosha. Ndiyo `ACTH Stimulation Test`. Ngatitaurei nezvazvo zviri nyore.

Chii chinonzi bvunzo yeACTH (ACTH Stimulation Test)?

Zvichitaurwa zviri nyore, iyi bvunzo yakakosha inotarisa kuti ma adrenal glands mumuviri wedu anopindura sei kune hormone inonzi ACTH. Dzimwe nguva iyi inonziwo Cosyntropin Stimulation Test (CST). Iyi ndiyo bvunzo huru yekuona kana paine chirwere chinonzi adrenal insufficiency, chinova kudzikira kwebasa re adrenal glands. Izvi zvinogona kuva zvekutanga, zvechipiri kana zvechitatu.

Kuongororwa uku kunosanganisira kubaya jekiseni reACTH hormone (Synthetic ACTH - Cosyntropin) mutsandanyama yako. Zvadaro, hafu yeawa yega yega kana kupfuura, ropa rako rinotorwa uye huwandu hwehormone inonzi cortisol hunoongororwa. Izvi zvinoitirwa kuona kuti adrenal glands yako iri kushanda zvakanaka sei.

Chii chinonzi ACTH neCortisol?

`ACTH`, iyo inomiririra `Adrenocorticotropic Hormone`, ihormone inogadzirwa ne`Pituitary Gland` iri muuropi hwedu. Ine simba guru pakuita kunoita muviri wedu kushushikana. Kana `ACTH` yaburitswa, inokurudzira ma adrenal glands kuti agadzire `Cortisol`, inozivikanwawo se`stress hormone` . Cortisol ihormone inokosha inokanganisa nhengo dzese dzemuviri wedu.

Mhando dzeAdrenal Insufficiency

Izvi zvinogona kuitika nenzira nhatu huru:

1. Kusakwana Kweadrenal: Izvi zvinoitika kana adrenal glands yako yakakuvara uye isingakwanise kugadzira cortisol zvakanaka. Chikonzero chikuru cheizvi chirwere cheAddison. Ichi chirwere chinokonzerwa ne autoimmune.

2. Kusakwana kweAdrenal Secondary: Izvi zvinoitika kana pituitary gland yako isingabudise ACTH yakakwana. Zvadaro adrenal glands hadzina kukurudzirwa zvakakwana kuti dzigadzire cortisol.

3. Kusakwana kweAdrenal Yepamusoro: Izvi zvinoitika kana hypothalamus iri muuropi isingagadzire hormone inonzi `CRH (Corticotropin-Releasing Hormone)` nemazvo. `CRH` ndiyo inoudza pituitary gland kuti igadzire `ACTH`.

Kuongororwa kweACTH kunodiwa rini?

Kuongororwa uku kunogona kuona kana adrenal glands yako nepituitary gland zviri kushanda nemazvo pakugadzira cortisol. Chiremba wako anogona kuraira bvunzo iyi nekuda kwezvikonzero zvinotevera:

• Kana imwe ongororo ikaona kuti mazinga e cortisol ari pasi.
• Kana uine zviratidzo zvekusashanda zvakanaka kweadrenal cortex (semuenzaniso, kuneta nguva dzose, kudzikira kwehuremu, kurwadziwa nemudumbu, kuda kurutsa, dzungu, ganda dema ).
• Mushure mekunge marega kushandisa mishonga yeglucocorticoid, yakadai seprednisone, kwenguva yakati, tarisai kuti muone kana magland enyu epituitary neadrenal adzoka pakuva akajairika.

Ndiani ari kuita bvunzo iyi?

Kazhinji, jekiseni reACTH rinoitwa nemukoti. Kutorwa kweropa, kureva kuti, sampuli yeropa, kunoitwa nenyanzvi yephlebotomist, kureva kuti, munhu akadzidziswa basa iri. Zvadaro sampuli idzi dzinotumirwa kurabhoritari. Ikoko, nyanzvi yesainzi yerabhoritari yezvekurapa inoongorora sampuli idzi.

Bvunzo iyi inowanzoitwa muchipatara kana muhofisi yechiremba we endocrinologist, chiremba anonyanya kubata zvirwere zvine chekuita nemahormone. Izvi zvinosanganisira kubaya mushonga nekubaya jekiseni uye kutora masampuli eropa. Nyanzvi ye endocrinologist chiremba anonyanya kubata zvirwere zvine chekuita nemahormone.

Ndinofanira kugadzirira chero chinhu here bvunzo isati yaitwa?

Ehe, pane zvimwe zvinhu.

• Ungakumbirwa kuti uderedze maekisesaizi ako uye udye chikafu chine makabhohaidhiretsi akawanda maawa 12-24 bvunzo isati yaitwa.
• Unogonawo kutaura kuti uchatsanya kwemaawa angangoita matanhatu. Izvi zvinoreva kuti haugone kudya kana kunwa chero chinhu kunze kwemvura.
• Kana uri kutora mimwe mishonga inogona kukanganisa bvunzo ye cortisol, unogona kukumbirwa kuti urege kuishandisa kwenguva pfupi.
• Sezvo huwandu hwe cortisol huchisiyana mukati mezuva (hwakanyanya kukwira mangwanani), bvunzo iyi inonyanya kuitwa mangwanani kuderedza njodzi yemhedzisiro yenhema.

Zvisinei, chiremba wako achakupa mirairo chaiyo yekuti ungagadzirira sei bvunzo iyi. Unofanira kutevedzera mirairo iyoyo nemazvo.

Kuongororwa kweACTH kunoitiswa sei?

Aya ndiwo matanho ekutanga:

1. Kutanga, ropa rinotorwa kubva mutsinga iri muruoko rwako. Izvi zvichaongorora huwandu hwekutanga hwe cortisol mumuviri wako. Dzimwe bvunzo dzinogona kuitwawo.

2. Zvadaro, mukoti achaisa jekiseni rehomoni rinonzi `ACTH (Cosyntropin)` mutsandanyama yako. `ACTH` iyi inoshanda se`ACTH` inogadzirwa nemuviri wedu, ichikurudzira ma adrenal glands kuti agadzire cortisol.

3. Zvadaro, mushure memaminitsi makumi matatu nemaminitsi makumi matanhatu (kazhinji), ropa rinotorwa kubva mutsinga yako zvakare uye huwandu hwecortisol hunoongororwa.

4. Masampuli eropa aya anotumirwa kurabhoritari.

Rudzii rwechiitiko chaunowana panguva yebvunzo?

Heano zvimwe zvinhu zvaunogona kutarisira kana uchitorwa ropa rako:

• Uchagara pachigaro uye tsinga iri muruoko rwako ichaonekwa iri nyore. Kazhinji, inenge iri mukati meruoko rwako, seri kwegokora rako.
• Kana tsinga yawanikwa, nzvimbo yacho inocheneswa uye inopiswa nemishonga inouraya utachiona.
• Zvadaro tsono diki inopinzwa mutsinga yeropa uye ropa rinotorwa. Izvi zvinogona kuita sekunge munhu ari kubaya zvishoma.
• Mushure mekupinza tsono, ropa diki rinoungana muchubhu yekuyedza.
• Kana ropa rakawanda raunganidzwa kuti riongororwe, tsono inobviswa uye chidimbu chedonje kana jira chinoiswa panzvimbo yacho chodzvanywa kuti ropa risabude.
• Zvadaro plaster inoiswa panzvimbo yacho.

Kana wawana Cosyntropin, inowanzoiswa muruoko rwako rwepamusoro, pamusoro pefudzi rako. Unganzwa kurwadziwa kana kupisa kana wawana jekiseni, asi ndezvenguva pfupi.

Chii chinoitika mushure mekuyedzwa?

Mushure mekunge ropa ratorwa, rinotumirwa kurabhoritari. Kana zvabuda, chiremba wako achakuudza nezvazvo.

Pane njodzi here nebvunzo iyi?

Kuongororwa ropa chinhu chinowanzoitika mukurapa. Njodzi dzacho dzakaderera. Unganzwa kukuvadzwa kana kurwadziwa pawakatorwa ropa, asi izvozvo zvinokurumidza kupera. Hapana chekunetseka nacho.

Zvinotora nguva yakareba sei kuti uzive mhedzisiro?

Zvinogona kutora kusvika vhiki kuti mhedzisiro yebvunzo yeACTH idzoke, nekuti kana mhedzisiro yerabhoritari yadzoka, chiremba anofanira kuidzidza nokungwarira uye kusvika pamhedziso.

Migumisiro yacho ndeipi?

Mishumo yekuongororwa kweropa, kusanganisira mishumo ye cortisol kubva ku ACTH test, inowanzova neruzivo rwakadai:

• Zita rekuongororwa kweropa, kana kuti chii chakayerwa muropa.
• Nhamba kana chiyero chemhedzisiro yekuongororwa kweropa rako.
• Ndiyo nzira yakajairika yekuyera bvunzo.
• Ruzivo rwekuti mhedzisiro yako yakajairika here, isina kujairika, yakakwira, kana yakaderera.

Mhedzisiro yeavhareji inofanira kunge yakaita sei?

Mumamiriro ezvinhu akajairika, huwandu hwe cortisol yako hunofanira kuwedzera mushure mekukurudzirwa kweACTH. Mumhedzisiro yakajairika, huwandu hwe cortisol yako hunofanira kupfuura 12.6 mcg/dL (ma micrograms pa deciliter) mushure mekukurudzirwa kweACTH.

Yeukai kuti, huwandu uhwu hwezviyero zvinogona kusiyana kubva murabhoritari kuenda kune imwe, bvunzo kuenda kune imwe, uye munhu nemunhu. Gara uchitarisa huwandu hwakajairika hwakapihwa pamushumo wako.

Kana paine bvunzo yeACTH, chiremba wako kana chiremba we endocrinologist anofanira kunyatsonzwisisa zvabuda musati mazviona. Kana muine mibvunzo nezve zvabuda muongororo iyi, iva nechokwadi chekubvunza chiremba wenyu.

Zvinorevei mhedzisiro isina kujairika?

Chiremba wako kana chiremba we endocrinologist achanyatsoongorora zvabuda mubvunzo dzako dzeACTH. Pane zvinhu zvakawanda zvinogona kukanganisa kururama kwebvunzo. Chikonzero chinowanzoita kuti pave nemhedzisiro yenhema kushandiswa kwemishonga ye corticosteroid munguva pfupi yapfuura.

Mhedzisiro yekuongororwa kweACTH isina kujairika inowanzo ratidza kusakwana kwe adrenal cortex.

Kusakwana kweAdrenal Yekutanga

Kana uine chirwere ichi, adrenal glands yako haigone kugadzira cortisol kana kuti haigone kupindura zvakanaka kuACTH. Saka, ungasaona kuwedzera kukuru kana kuwedzera kwemazinga e cortisol yako mushure mekuongororwa kweACTH. Izvi zvinokonzerwa nekuti ACTH yekugadzira haina kukanganisa adrenal glands yako.

Kusakwana kweAdrenal yechipiri

Kana pituitary gland ikasashanda zvakanaka kwenguva yakareba (hypopituitarism), uye kugadzirwa kweACTH kukakanganiswa, izvi zvinotungamira kukusakwana kweadrenal cortex. Nekuda kweizvozvo, masero anowanzo gadzira ACTH haakurudzirwi, uye adrenal glands dzinotanga kudonha, kureva kuti, dzinotanga kupera simba .

Saka, kana wagara uine hypopituitarism uye adrenal insufficiency kwenguva yakareba, ungangoona kuwedzera kudiki kana kusawedzera kwe cortisol yako mushure mekuongororwa kweACTH.

Zvisinei, kana hypopituitarism iri chikamu (zvichireva kuti pituitary gland ichiri kugadzira ACTH), kana kuti chirwere ichi chave chichangobva kuitika, kuwedzera kwemazinga e cortisol, zvichireva kuti "mazinga akajairwa", kunogona kuonekwa mushure mekuongororwa kweACTH.

Mharidzo Yekupedzisira Yekuenda Kumba

Kuongororwa kweACTH Stimulation ndiyo bvunzo inonyanya kukosha uye yakavimbika yekuongorora kusakwana kweadrenal cortex. Kumirira mhinduro yebvunzo yekuongorora kunogona kunetsa zvishoma. Asi yeuka, zvisinei nekuti mhinduro dzacho dzakaita sei, timu yako yezvekurapa iripo kuti ikubatsire. Usatya kubvunza chiremba wako nezvebvunzo yako kana mhinduro dzacho. Zvakakosha kuziva nezvehutano hwako.

Kuongororwa kweACTH , cortisol, adrenal glands, pituitary gland, mahormone, adrenal insufficiency, bvunzo dzekurapa