Ngatidzidzei nezveAldosterone, iyo inokanganisa BP yako muchivande.

Dambudziko rine vanhu vazhinji muSri Lanka ndere BP yakakwira. Kune vamwe, zvakaoma kudzora izvi kunyangwe mushure mekunwa mushonga. Asi pane mumwe munhu ari mumiviri yedu watisingataure nezvake zvakanyanya, asi achipesvedzera BP muchivande. Ndizvo zvatichataura nezvazvo nhasi. Zita rake rinonzi Aldosterone.

Zvichitaurwa zviri nyore, ndiani uyu aldosterone?

Aldosterone ihormone iri mumuviri wedu. Mahormone akafanana neanoshanda mupositi mumuviri wedu. Anotakura mashoko kunhengo yega yega, achiiudza kuti iite izvi, rega izvo.

Saka homoni iyi inonzi aldosterone inogadzirwa nemagland maviri madiki akaita sechivharo pamusoro peitsvo dzedu. Tinoti aya magland eadrenal. Magland aya chikamu chehurongwa hwedu hwe endocrine.

Basa guru rehomoni iyi nderekuchengetedza BP yedu iri padanho rakakodzera . Inoita izvi nekudzora huwandu hwezvicherwa muropa redu zvinonzi sodium (ndiyo munyu) nepotassium. Aya sodium nepotassium mhando mbiri dze electrolytes . Ndiwo anochengetedza huwandu hwemvura mumuviri hwakaringana uye anobatsira tsinga netsandanyama kushanda zvakanaka.

Aldosterone inodzora sei BP?

Iyi inzira inonakidza zvikuru. Aldosterone inonyanya kukanganisa BP nenzira dzinotevera:

1. Kuchengetwa kweSodium: Aldosterone inozivisa itsvo dzedu neura kuti "dziwedzere sodium (munyu) muropa uye kuwedzera huwandu hwepotassium inobuda muweti."

2. Kuchengetwa kwemvura: Kana sodium ikaiswa muropa, mvura inochengetwawo mumuviri. Zvakafanana nemvura inokwezvwa nemunyu.

3. Kuwedzera kwehuwandu hweropa: Patinochengeta mvura mumiviri yedu, huwandu hweropa redu rose hunowedzera. Kungofanana nekuzadza pombi yemvura nemvura yakawanda kunowedzera kumanikidzwa kwayo, kana huwandu hweropa huchiwedzera, BP inowedzerawo.

Nenzira iyi, kana BP yedu yadzikira, aldosterone inopinda uye inobatsira kuidzosera padanho rakanaka. Homoni iyi inobatsirawo nenzira isina kunanga kudzora pH (kureva, acid-base balance) uye mazinga e electrolyte muropa.

Mazinga aya e aldosterone anodzorwa sei? - Maitiro anoshamisa!

Aldosterone haishande yoga. Inhengo yechikwata chinoshanda pamwe chete. Isu tinodana sisitimu iyi kuti Renin-Angiotensin-Aldosterone System (RAAS) . Zvakafanana nemujaho we relay.

Funga nezvazvo nenzira iyi.

• Danho rekutanga: Kumanikidzwa kweropa rako (BP) kunodzikira. Itsvo dzedu dzinonzwa izvi. Itsvo dzinobva dzaburitsa enzyme inonzi renin muropa.
• Danho rechipiri: Renin iyi inopwanya puroteni inonzi angiotensinogen, inogadzirwa nechiropa chedu, kuita chidimbu chinonzi angiotensin I. Asi ichiri isina simba, zvinoreva kuti haina simba rakawanda.
• Danho Rechitatu: Zvino, sezvo angiotensin I iyi ichifamba nemuropa, inoputswa neangiotensin-converting enzyme (ACE) inobva mumapapu edu, zvichigadzira hormone ine simba zvikuru inonzi angiotensin II . Uyu ndiye gamba chairo.
• Danho Rechina: Iyi angiotensin II inoita zvinhu zviviri zvikuru.

1. Zvinoita kuti tsinga diki dzeropa (arterioles) dziome. Izvi zvinoita kuti BP ikwire nekukasika.

2. Inoenda kuma adrenal glands yovaudza kuti, "Njodzi! Inokurumidza kugadzira aldosterone!"

• Danho rekupedzisira: Iye zvino aldosterone inouya youdza itsvo kuti dzichengetedze munyu (sodium) nemvura uye dzibudise potassium. Izvi zvinowedzera huwandu hweropa uye zvinodzorera BP kune zvakajairika.

Kana maitiro ese aya apera, uye BP yadzoka payakajairika, sisitimu iyi inodzima yega. Iyi sisitimu yekudzora yakaoma kwazvo, asi inoshamisa kwazvo.

Mazinga ealdosterone anoyerwa sei?

Kana chiremba wako ari kunetseka kudzora BP yako, kana kuti kana uine shanduko muhuwandu hwepotassium muropa rako, anogona kufungidzira kuti aldosterone ine aldosterone. Muedzo mukuru weizvi ibvunzo ye aldosterone:renin ratio .

Nekuti aldosterone nerenin zvinoshanda pamwe chete, kuyera huwandu hwese kunogona kubatsira kuona nzvimbo chaiyo yedambudziko. Izvi zvinowanzoitwa nekutora ropa shoma kubva mutsinga iri muruoko rwako.

Pamusoro pezvo, mazinga ealdosterone anogona kuyerwa zvakasiyana muropa kana weti yakaunganidzwa mumaawa makumi maviri nemana.

Chii chinoitika kana huwandu hwealdosterone hukawedzera?

Kana huwandu hwealdosterone mumuviri hwakwira kupfuura zvakajairika, tinohudaidza kuti hyperaldosteronism . Chikonzero chikuru cheizvi chirwere chinonzi primary aldosteronism . IzviInonziwo Conn's syndrome.

Dambudziko iri rinowanzo kukonzerwa nebundu diki, risiri rekenza (risina njodzi) rinokura muadrenal gland. Bundu iri rinoita kuti gland rigadzire aldosterone yakawandisa. Izvi zvinokonzera kuwedzera kwe sodium (munyu) muropa, kudzikira kwe potassium, uye kusawirirana kwema electrolyte.

Chii chinoitika kana huwandu hwealdosterone hukadzikira?

Uyewo, kana huwandu hwealdosterone mumuviri hwakaderera pane hwakajairwa, tinohudaidza kuti hypoaldosteronism . Izvi zvinoitika kana hormone yealdosterone ikasagadzirwa zvakanyanya kana kuti kushanda kwayo kukanganisika. Izvi zvinogona kukonzera huwandu hushoma hwesodium (munyu) muropa, huwandu hwakawanda hwepotassium, uye chirwere chinonzi metabolic acidosis (kuwedzera kweacidity muropa) .

Ndezvipi zvikonzero zveizvi?

• Chirwere cheAddison:Ichi chirwere chisingawanzoitiki che autoimmune. Izvi zvinoreva kuti dziviriro yemuviri inozvirwisa yoga uye inokuvadza adrenal glands. Izvi zvinoderedza kugadzirwa kwemahormone e aldosterone ne cortisol.
• Congenital Adrenal Hyperplasia (CAH): Ichi chirwere chemajini chinowanikwa pakuzvarwa. Chinokonzera kushomeka kwema enzymes anodiwa kugadzira mahormone muadrenal glands.
• Zvimwe zvirwere: Chirwere ichi chinogona kuitika kuvanhu vane chirwere cheshuga, chirwere cheitsvo, uye avo vanorwara zvakanyanya.
• Mimwe mishonga: Chirwere ichi chinogonawo kukonzerwa nemishonga inoderedza marwadzo (NSAIDs) , mishonga inobvisa ropa rakaita seheparin, uye mimwe mishonga yemwoyo.

Kana uine zviratidzo izvi, zvakakosha kuti uronge nguva yekuonana nachiremba wako wotaura nezvazvo.