Kana munhu mukuru mumba medu, kureva amai vedu, baba, ambuya kana sekuru, akatanga kukanganwa zvinhu zvishoma nezvishoma, uye pavanobvunza chinhu chimwe chete kakawanda, kutya kunouya mumoyo medu, handiti? Mubvunzo wekuti "Uku ndiko kutanga kweAlzheimer's Disease here?" unoita kuti tizvidye mwoyo. Kutaura zvazviri, patinonzwa chirwere cheAlzheimer's, chinouya mupfungwa dzedu mamiriro ezvinhu anosuruvarisa apo tinorasikirwa nendangariro dzedu zvishoma nezvishoma, hatigoni kuita mabasa atinojaira, uye pakupedzisira tokanganwa kuti tiri vanaani. Ichokwadi. Asi waizviziva here kuti kune marudzi akati wandei echirwere ichi, zvichienderana nekuti chinokura sei, kureva kuti, zera rinotanga chirwere chacho uye zvikonzero zvacho? Ngatitaurei nezvazvo nhasi.
Kunyangwe mhando dzechirwere ichi dzichisiyana, zviratidzo zvakajairika zvakafanana.
Kutanga, ngatinzwisise izvi. Pasinei nerudzi rwechirwere cheAlzheimer, zviratidzo zvinoonekwa nevarwere vese zvakafanana nekufamba kwenguva.
- Kurasikirwa nendangariro: Kukanganwa zvinhu, kunyanya zvinhu zvitsva.
- Kuvhiringidzika: Kuvhiringidzika pamusoro pezvinhu zvakaita senguva, nzvimbo, nemazuva.
- Kuoma kuita mabasa akajairika: Kuoma kuita mabasa akareruka sekubika tii kana kupfeka mbatya uri wega.
- Kuomerwa nekuita zvisarudzo: Kunzwa wakarasika, usingakwanise kuita sarudzo iri nyore.
Chikonzero chikuru cheizvi zvese kuunganidzwa kwemhando yeprotein inonzi `amyloid beta peptides` mumasero etsinga europi hwedu. Zvichitaurwa zviri nyore, izvi zvakafanana nerudzi rwe "marara" anoungana muuropi. Kazhinji, uropi hwedu hunobvisa rudzi urwu rwezvinhu zvisina basa. Asi muchirwere cheAlzheimer, maitiro aya haaitike nemazvo. Ipapo mapuroteni aya anoungana ogadzira ma plaque uye anobatana muuropi. Nekuda kweizvi, kufamba kwemashoko pakati pemasero europi kunomira, uye masero anofa zvishoma nezvishoma. Pasinei nerudzi rwechirwere, maitiro aya akajairika.
Mhando mbiri huru dzechirwere cheAlzheimer's
Tinoiparadzanisa kuita mhando mbiri huru, zvichienderana nezera rekutanga kwayo. Ona tafura iri pazasi kuti unzwisise mutsauko uripo pakati pemhando mbiri idzi.
| Chinhu | Alzheimer's yekutanga | Alzheimer's inokurumidza kutanga |
|---|---|---|
| Zera rekutanga kwechirwere | Vari pasi pemakore 65. Kazhinji vari pakati pemakore ekuma40 ne50. | Makore makumi matanhatu nemashanu zvichikwira. |
| Kujairika | Hazviwanzoitiki, zvichiitika muvarwere vasingasviki 5%. | Iyi ndiyo mhando inonyanya kuwanikwa. |
| Mikana yekupfuudza zvizvarwa | Kazhinji pane hukama hwakasimba pakati pemajini. | Inogona kukura kunyangwe mumwe munhu mumhuri anayo kana kuti kwete. Jini chairo harisati razivikanwa. |
| Kuchinja kwehuropi | Mapundu akawanda uye mavanga anogona kuonekwa muuropi. Kune kuderera kweuropi kwakawanda. | Kunyangwe kana shanduko dzeuropi dzikaitika, dzinogona kunge dziri diki. |
| Zvimwe zvinhu | Kugwinha/kuzununguka kwetsandanyama kamwe kamwe (myoclonus) kunogona kuonekwa. | Kurasikirwa nendangariro kunova chiratidzo chikuru. |
Alzheimer's yekutanga
Izvi zvinganzwika sezvinoshamisa. Asi hongu, vamwe vanhu vanogona kubatwa nechirwere cheAlzheimer vachiri vadiki vane makore 40 kana 50. Ichi chirwere chisingawanzoitiki. Chinonyanya kukonzerwa nekusakwana kwemajini . Zvikuru, zvakaonekwa kuti chirwere ichi chinokonzerwa nekusakwana kwemachromosome 1, 14, uye 21, ane ruzivo rwemajini mumuviri wedu. Zvakare, vanhu vane Down syndrome vari panjodzi huru yekubatwa nechirwere cheAlzheimer's ichi.
Alzheimer's inokurumidza kutanga
Iyi ndiyo mhando yeAlzheimer's yatinonyanya kuziva. Zviratidzo zvinowanzotanga kuoneka mushure memakore makumi matanhatu nemashanu. Dzimwe nguva zvinogona kuitika mumhuri. Izvi zvinoreva kuti kana amai vaine chirwere ichi, mwana wavo anogona kunge ari panjodzi. Asi jini rakati, senge rudzi rwunokura pazera diki,Chikonzero chaicho chechirwere ichi hachisati chawanikwa. Nokudaro, vanachiremba nevesainzi vachiri kutsvaga kuti sei vamwe vanhu vachichiwana asi vamwe vasingachiwane.
Chii chinonzi Familyal Alzheimer's Disease (FAD)?
Pane chimwe chinhu chinovhiringidza vanhu vazhinji pano. "Mumwe munhu mumhuri aiva nacho" uye "Familial Autism Spectrum Disorder (FAD)" zvinhu zviviri zvakasiyana.
Chirwere cheAlzheimer chemhuri (FAD) chirwere icho vanachiremba vane chokwadi chekuti chinokonzerwa nemajini. Kuti zviongororwe kuti zvine chirwere ichi, zvizvarwa zviviri zvemhuri (semuenzaniso, ambuya naamai) zvinofanira kunge zvakambova nacho. Hazviwanzoitiki, zvichireva kuti vanhu vari pasi pe1 % yevarwere vese vane Alzheimer's. Vanhu vazhinji vanobatwa nechirwere cheAlzheimer vachiri vadiki vane rudzi urwu rweFAD.
Kana iwe kana mumwe munhu mumhuri yako ari kunetseka nekuyeuka, musangofungidzira kuti, "Izvi zvinhu zvekare" kana kuti "ingori nhoroondo yemhuri." Inogona kunge iri chirwere chinorapika. Saka chinhu chakanakisa chekuita ndechekuona chiremba wako nekukurumidza uye kuongororwa kwakakodzera.
Mharidzo Yekuenda Nayo Kumba
- Chirwere cheAlzheimer chinogona kuuya nenzira dzakasiyana-siyana. Kurongwa uku kunonyanya kuenderana nezera rinotanga chirwere ichi (kutanga kwekutanga uye kunonoka kutanga).
- Rudzi rwekutanga kwechirwere ichi, runoonekwa nevanhu vari pasi pemakore makumi matanhatu nemashanu, haruwanzoitiki. Rune hukama hwakasimba pakati pemajini.
- Chinokonzera majini chaiwo hachisati chawanikwa cherudzi rwekutanga kunonoka kwatinoona kakawanda, runokura mushure memakore makumi matanhatu nemashanu.
- Usafunge kuti nekuti mumwe munhu mumhuri mako ane chirwere cheAlzheimer, iwe uchachiwanawo. Asi zvakakosha kuziva nezvenjodzi yacho.
- Kana paine dambudziko rekuyeuka, kutsvaga rubatsiro rwechiremba nekukasika pane kusaruteerera kunobatsira zvikuru murwere nemhuri.
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