Tariro itsva yechirwere cheAlzheimer! Ngatidzidzei nezvemushonga weLeqembi (lecanemab)?

Amai vako, baba vako, kana mumwe munhu waunoziva ari kuramba achikanganwa here? Kukanganwa zvinhu zvidiki zvakaita sekuti makiyi ako ari kupi kana zita remumwe munhu zvinogona kuva chiratidzo chekutanga chechirwere cheAlzheimer. Kunyangwe hazvo kuchine mushonga wechirwere ichi chakakomba, mushonga mutsva unogona kunonotsa kufambira mberi kwechirwere wabvumidzwa zvizere neUS FDA (Food and Drug Administration). Iyi itarisiro huru kune varwere pasi rese. Saka ngatitaurei zvishoma nezvemushonga mutsva uyu, Leqembi.

Chii chinonzi mushonga mutsva uyu unonzi Leqembi?

Chinhu chekutanga chaunofanira kunzwisisa ndechekuti iyi haisi mushonga wechirwere cheAlzheimer. Asi inobatsira. Inogona kunonotsa kufambira mberi kwechirwere. Tsvagiridzo yakaratidza kuti inogona kunonotsa kufambira mberi kwechirwere neinenge 27% mukati memwedzi gumi nemisere.

Zvino ungave uchifunga kuti, 'Zvichaita mutsauko zvechokwadi here?' Ehe, zvichaitika zvechokwadi. Ingofunga, munhu anotora mushonga uyu achakwanisa kurarama kwemwedzi mishanu kwenguva refu asina zviratidzo zvinotowedzera kuipa kupfuura munhu asingatore mushonga, uye achakwanisa kuita basa rake ega, kufara nemhuri yake, kuenda kunoona muzukuru wake akapedza kudzidza... Nguva iyoyo yekuwedzera inokosha sei yekuita zvinhu zvakaita seizvi? Nguva iyoyo ndiyo bhenefiti huru yemushonga uyu.

Mushonga uyu unoshanda sei?

Kuti tinzwisise izvi, ngatitorei muenzaniso mudiki. Muuropi hwevarwere vane Alzheimer's, puroteni isingadiwe inonzi amyloid plaques inochengetwa. Zvakafanana nevhu rinonamirwa mupombi yemvura uye rinonamirwa zvishoma nezvishoma mupombi. Nekuda kwekuiswa kwemapuroteni aya, kutaurirana pakati pemasero europi kunokanganiswa, uye masero anotanga kufa zvishoma nezvishoma. Ndokusaka ndangariro dzichirasika uye maitiro anochinja.

Mushonga uyu, unonzi Leqembi, unobata nekubvisa ma plaque e amyloid akaungana muuropi. Uri weboka remishonga inonzi monoclonal antibodies. Mushonga uyu unowanzopihwa murwere kaviri pamwedzi kuburikidza ne IV infusion.

Ngatitarisei zvimwe zvinhu zvakakosha nezvemushonga uyu patafura.

Pane njodzi here pakushandisa izvi?

Ehe. Kufanana nemishonga yese, iyi ine njodzi uye migumisiro. Kutaura zvazviri, FDA yakaburitsa "nyevero yebhokisi dema" pamushonga uyu, inova yambiro yepamusoro-soro yekuchengetedzwa . Chikonzero cheizvozvo chirwere chinonzi ARIA.

Chii chinonzi ARIA?

ARIA ishoko rinotsanangura Amyloid-Related Imaging Abnormalities. Muchidimbu, mushonga uyu unogona kukonzera kuti vamwe vanhu vazvimbe muuropi kana kubuda ropa diki (microbleeds) . Kunyange zvazvo izvi zvisingawanzoitiki zvakanyanya, dzimwe nguva zvinogona kuisa hupenyu panjodzi.

• Jini reAPOE4: Vanhu vane makopi maviri ekuchinja kwemajini eAPOE4 vari panjodzi huru yekuva nechirwere ichi cheARIA kupfuura vamwe.
• Zvinoderedza Ropa: Chimwe chinhu chakakosha ndechekuti vanachiremba vanoyambira zvakasimba kuti vasashandise mushonga uyu kune munhu ari kutora mishonga inobvisa ropa. Nekuti kana ukadaro, pane mukana mukuru wekuti kubuda ropa kudiki kugoshanduka kuita kubuda ropa kukuru, kunouraya (macro-bleed). Dzimwe nguva izvi zvinogona kukonzera pfari, kugara muchipatara, kana kutofa.

Saka, usati watanga mushonga uyu, zvakakosha kuti unyatso kurukura nezvenjodzi idzi nachiremba wako, uite bvunzo dzinodiwa, uye usimbise kana izvi zvakakunakira.

Saka ndoita sei?

Kana iwe, muverengi wenyaya ino, uine kana kakufungira kuti iwe kana mumwe munhu ari pedyo newe ane zviratidzo zvekutanga zvechirwere cheAlzheimer, chinhu chakanakisa chekuita ndechekuona chiremba nekukurumidza uye kuwana chirwere chakarurama.

Nekuti sezvatakambokurukura, mishonga yakaita seLeqembi inobatsira chete pakutanga kwechirwere. Kana ukanonoka, unogona kurasikirwa nemukana wekurapwa. Uyewo, mishonga mitsva yakaita seyi inowanzo kudhura. Saka zvakanaka kutaura nachiremba wako nezvazvo usati watanga kurapwa.

Nyanzvi dzinotenda kuti munguva pfupi iri kutevera, mishonga ichawanikwa inogona kuona nekudzivirira chirwere vanhu vasati varatidza zviratidzo. Sezvatinogona kuona nekurapa kenza yemazamu nekenza yeprostate nekukurumidza, rimwe zuva tichakwanisa kuona nekudzivirira chirwere cheAlzheimer nekukurumidza. Kusvika panguva iyoyo, mishonga yakaita seLeqembi inopa tariro huru kwatiri tese.