Kana iwe kana mumwe munhu waunoziva aine kenza, ungave wakaona kuti nekufamba kwenguva, muviri wake wava mutete uye unotoita sewakasiyana. Vanhu vazhinji vanofunga kuti ichi chikamu chekenza kana kuti mhedzisiro yekurapwa. Izvozvo zvinogona kunge zviri zvechokwadi kusvika pamwero wakati. Zvisinei, chirwere ichi dzimwe nguva chinogona kunge chiri chimwe chinhu chakadzama, chirwere chinonzi cancer cachexia . Ngatitaurei nezvazvo zvakadzama nhasi, nekuti chinokanganisa hupenyu hwevarwere vekenza uye maitiro avo pakurapwa.

Chii chinonzi Cancer Cachexia?

Zvichitaurwa zviri nyore, cancer cachexia chirwere chakakomba chekurasikirwa nehupenyu chinokonzerwa nekenza. Apa ndipo paunorasikirwa netsandanyama dzakawanda dzemapfupa nemafuta emuviri . Hazvisi zvekungoderedza huremu chete, asiwo tsandanyama dzinopa simba. Kudzikira uku kwehuremu kunogona kuchinja chitarisiko chako, kukukonzera kusagadzikana mupfungwa, uye kutoita kuti zviome kurarama nekurapwa nekenza. Zvinogonawo kukanganisa hupenyu hwako uye dzimwe nguva kukanganisa kugona kwako kurarama nekenza.

Nyanzvi dzinoti chirwere ichi chinokanganisa vanhu vanosvika 50% vane kenza. Zvakare, chinogona kuonekwa muvanhu vanosvika 75% vane kenza yakapararira, kureva kuti, mukenza yeDanho rechina . Zvinosuwisa kuti chirwere ichi ndicho chinokonzera 25% yekufa kwekenza.

Kunyangwe chirwere ichi chichigona kuitika chero murudzi rupi zvarwo rwegomarara, chinonyanya kuitika kuvanhu vane mhando idzi dzegomarara:

• Kenza yemudumbu
• Kenza yemapapu
• Melanoma, rudzi rwekenza yeganda
• Kenza yepancreatic

Kunyange hazvo vanachiremba vasingakwanise kurapa cachexia yekenza zvachose, kurapwa kunoedza kuwedzera huwandu hwechikafu chaunodya, kunyanya kutarisa pakudya zvine mapuroteni akawanda uye zvine macalorie akawanda .

Ndezvipi zviratidzo zve cancer cachexia?

Chiratidzo chikuru uye chinonyanya kuoneka chechirwere ichi kurasikirwa neanopfuura 10% yehuremu hwemuviri wako wese mumwedzi 6 kusvika ku12 yapfuura . Izvi zvinosanganisira tsandanyama nemafuta. Kunze kweizvozvo, panogona kunge paine zvimwe zviratidzo zvakawanda:

• Kuneta kwakanyanya uye kushaya simba: Unganzwa sekuti hauna simba rakakwana rekuita mabasa ako ezuva nezuva, kutarisira mhuri yako, kana kutoita mabasa ako epamba. Zvinoita sekuti hauna hupenyu.
• Kurasikirwa kwetsandanyama: Vanachiremba vanotiwo kurasikirwa kwetsandanyama kana kuti kuderera kwetsandanyama . Uku kurasikirwa kwetsandanyama nekudzikira kwetsandanyama.
• Anorexia: Apa ndipo paunorasikirwa nechido chekudya chose, haunzwi nzara. Dzimwe nguva hautombodi kufunga nezvechikafu. Asi izvi zvakasiyana nedambudziko rekudya rinonzi anorexia nervosa ratakanzwa nezvaro.
• Anemia: Unogona kuwana anemia nekuti muviri wako, nekuda kwekuzvimba, unoburitsa puroteni inokanganisa kugadzirwa kwemasero matsvuku eropa.
• Kutapukirwa nezvirwere: Cancer cachexia inogona kuderedza simba remuviri wako, zvichiita kuti usakwanise kurwisa zvirwere. Izvi zvinogona kuita kuti utapurwe nezvirwere.

Sei cachexia yekenza iyi ichiitika?

Pane zvikonzero zvakawanda zveizvi. Gomarara rinokurumidzisa metabolism yako. Izvi zvinoreva kuti muviri wako unoda simba rakawanda kubva muchikafu. Panguva imwe chete, kurapwa kwegomarara negomarara kunogonawo kuderedza havi yako yekudya. Mugumisiro wacho ndewekuti unodya zvishoma kana muviri wako uchida zvinovaka muviri zvakawanda.

Heano zvimwe zvikonzero zvinokanganisa mamiriro ezvinhu aya:

• Mamwe marudzi emacytokine: MaCytokine makemikari anodzora kuti masoja edu emuviri anopindura sei uye riini kune zvinopinda mumuviri zvakaita semavhairasi. Mukenza cachexia, masoja ako emuviri anoburitsa mamwe marudzi emacytokine. Izvi zvinokonzera kuzvimba, izvo zvinowedzera mwero wekuti muviri wako unopwanya mafuta netsandanyama. Cancer inokonzerawo kuzvimba, uye macytokine aya anogona kuwedzera kuzvimba ikoko.
• Zviratidzo zvegomarara nemigumisiro yaro: Marwadzo, kuda kurutsa, uye kurutsa zvinokonzerwa negomarara zvinogona kuita kuti udye zvishoma. Uyewo, kuva negomarara kunogona kuita kuti unzwe kuora mwoyo uye ushaye chido chekudya.
• Migumisiro yekurapwa kwegomarara: Zvinhu zvakaita sekuvhiyiwa, kurapwa nemwaranzi , chemotherapy , uye mimwe mishonga yekurapa marwadzo yeopioid zvinogona kukonzera kuoma kumedza kana kukanganisa kugona kwemuviri kupinza zvinovaka muviri.
• Kuramba insulin: Izvi zvinoreva kuti tsandanyama dzako nemasero emafuta hazvipinduri zvakanaka ne insulin. Kuramba insulin uku, kunoitika mu cachexia, kunogona kukonzera kurasikirwa kwetsandanyama zvakanyanya.
• Kuwedzera kwekuchinjana kwemapuroteni: Kuchinjana kwemapuroteni inzira iyo mapuroteni ekare mumasero ako anotsiviwa nemapuroteni matsva. Izvi zvinoitika kuburikidza nekuora kwemapuroteni . Mu cancer cachexia, mapuroteni ari mumasero anopwanyika nekukurumidza zvekuti mapuroteni matsva haakwanise kutsiva. Izvi zvinokonzerawo kurasikirwa kwemhasuru.

Ndezvipi zvinetso zvinokonzerwa nekenza cachexia?

Dambudziko iri rinogona kutokonzera njodzi kuhupenyu. Semuenzaniso, funga nezve cachexia, iyo inonyanya kukonzera rufu mu20% kusvika 25% yevarwere vane bundu rakasimba rakapararira, senge kenza yemapapu kana prostate, apo kenza inopararira kune dzimwe nhengo dzemuviri.

Mamwe matambudziko anogona kusanganisira:

• Kukanganiswa kwekurapwa kwegomarara: Muviri wako unoda tsandanyama nemafuta kuti upore kubva mukurapwa kwegomarara. Kurasikirwa neizvi kunogona kukanganisa kugona kwako kurapwa gomarara. Ungatorasikirwa nesimba rekutsungirira kurapwa.
• Matambudziko ehutano hwepfungwa: Kuonekwa uine cancer cachexia kunogona kureva kuti une mwedzi chete yekurarama. Ruzivo urwu runogona kuita kuti unzwe kunetseka uye kuora mwoyo.
• Kukanganisa mhuri neshamwari: Chirwere ichi chinogonawo kukanganisa hukama hwako nemhuri neshamwari. Haungonzwi kusuruvara chete paunoona shanduko mumuviri wako, asi vanokuchengeta vanogonawo kunetseka nezvehutano hwako. Ongororo dzakaratidza kuti kana nhengo dzemhuri dzikaona zviratidzo izvi, dzinogona kumanikidza murwere kuti adye, kunyangwe nekuda kwerudo, izvo zvinogona kukonzera kusawirirana kusingakoshi uye kuwedzera mamiriro ezvinhu anonetsa kare.

Fungidzira, kana nhengo yemhuri yakaonda nekuda kwekenza uye isingakwanise kudya, zvakajairika kusimbirira kuti, "Ndapota idyai zvishoma, ndapota idyaiwo ichi." Asi izvozvo zvinogona kutowedzera kushungurudza murwere.

Vanachiremba vanoongorora sei cachexia yekenza?

Chikwata chako chekurapa kenza uye/kana chekuchengetedza varwere vanorwara nechirwere ichi chichakuongorora muviri wako. Vanogona kukukumbira kuti uzadze mibvunzo ine chekuita nekudya kwako, uye vanogonawo kuita bvunzo dzekuyera kusimba kwemuviri wako uye simba retsandanyama.

Pamusoro pezvo, CT scan kana DXA scan ingakurudzirwa. Iyi DXA scan inoyera huwandu hwenyama dzakaonda dziri mumaoko nemakumbo ako. Inogona kupa chiremba wekenza pfungwa yehukuru hwetsandanyama dzako. Mhedzisiro yebvunzo idzi ichabatsira chiremba kuona danho rechirwere.

Matanho e cancer cachexia ndeapi?

Kune matanho matatu makuru e cachexia yekenza:

• Pre-cachexia: Muchikamu chino, uri kudzikira huremu kunyangwe uchidya zvakanaka. Zvisinei, hauna kudzikira huremu hunopfuura 5% yehuremu hwako hwese mumwedzi 6-12 yapfuura. Kana wakafuta, kudzikira uku kwehuremu kungasaonekwa, asi bvunzo dzinoratidza kuti shanduko dzemuviri dzakaitika uye uri kudzikira tsandanyama pamwe nemafuta.
• Cachexia:Pari zvino, warasikirwa neuremu hwemuviri wako hunopfuura 5% mumwedzi 6-12 yapfuura, kana kuti warasikirwa neuremu hwemuviri wako hunopfuura 2%, uye body mass index yako (BMI) iri pasi pe20kg/m². Kuongororwa kunogona kuratidza zviratidzo zvekurasikirwa netsandanyama uye kuzvimba.
• Refractory cachexia: Panguva ino, warasikirwa neanopfuura 20% yehuremu hwako hwemazuva ese uye BMI yako iri pasi pe27 kg/m² (izvi zvingaita sezviri pamusoro, asi zvakanyanya kana zvikabatanidzwa nekudzikira kwehuremu zvakanyanya). Kudzikira kwehuremu hwako kunogona kuita kuti utaridzike seusina kunaka uye kukutadzisa kurarama nekurapwa kwegomarara. Mune zvimwe zviitiko, kurapwa kwegomarara kunogona kutomira kushanda.

Ndeipi mishonga yekurapa cancer cachexia?

Kurapwa kwenyu kuchanyanya kutarisa nzira dzekuvandudza kudya kunovaka muviri . Semuenzaniso, timu yenyu yegomarara nechikwata chevanorapa varwere vanogona kukurudzira zvinhu zvakaita se:

• Idya zvakanaka: Tarisa pakudya zvidiki uye zvekudya zvine macalorie akawanda, mafuta, uye mapuroteni . Kudya zvidiki kuchakubatsira kuwana macalorie akawanda. Taura nenyanzvi yako yezvekudya nezvekudya zvipi zvichakubatsira kuwana zvakawanda kubva pane zvese zvaunodya. Vanogona kukurudzira kuwedzera zvinhu zvakaita sechizi, bota, nzungu, uye mukaka usina mafuta akawanda mukudya kwako.
• Edza mishonga yekuwedzera: Bvunza chiremba wako wekenza kana nyanzvi yezvekudya nezvemishonga yekuwedzera inogona kunwa kana kudya pakati pekudya. Izvi zvinogona kukupa kudya kwakawedzerwa.
• Ita maekisesaizi: Maekisesaizi akareruka anogona kubatsira kuderedza kurasikirwa netsandanyama, asi izvi zvinofanirwa kuitwa chete kana wapihwa zano nachiremba.
• Vimba nechikwata chako chekurapa: Chikwata chako chekurapa varwere vanogona kukubatsira nezvinhu zvakaita sehutano hwepfungwa uye rutsigiro rwemweya. Rutsigiro irworwo runokosha panguva ino.

Pane mishonga yekurapa cachexia here?

Kwete panguva ino. Kunyangwe tsvakurudzo ichiratidza kuti mushonga unonzi megestrol acetate unogona kuwedzera chido chekudya uye kukubatsira kuwedzera uremu, U.S. Food and Drug Administration (FDA) haisati yaubvumidza kurapa cancer cachexia. Mune zvimwe zviitiko, chiremba wako anogona kukupa mushonga we corticosteroids kwenguva pfupi.

Chii chingatarisirwa nemunhu ane cancer cachexia?

Zvinoenderana nemamiriro ako ezvinhu. Kureva kuti, uri padanho ripi re cachexia, uri padanho ripi re cancer. Semuenzaniso, kana uine pre-cachexia, kuchinja zvaunodya kunogona kuderedza mwero wekurasikirwa kwako nemafuta netsandanyama. Asi, zvinosuwisa kuti, kunyangwe ukawedzera huwandu hwaunodya, haugone kumisa zvachose kurasikirwa kana kudzorera tsandanyama nemafuta zvakarasika.

Kana uine kenza yakanyanya uye cachexia, kana cachexia isingapindure kana warapwa (refractory cachexia), chiremba wako wekenza anogona kutaura kuti wava pedyo nekuguma kwehupenyu hwako. Kana uri kurapwa cachexia, timu yako yezvekurapa inogona kukupa ruzivo rwakanakisisa nezvezvaunotarisira.

Munhu ane cancer cachexia anotarisirwa kurarama kwenguva yakareba sei?

Nguva yekurarama inosiyana kubva pamunhu nemunhu. Kunyangwe cancer cachexia ichiwanzobata vanhu vane cancer yakakura, unogona kuva nezviratidzo zve pre-cachexia chero padanho ripi zvaro recancer yako. Kana izvozvo zvikaitika, unogona kurarama nematambudziko akadai secancer uye cachexia kwemakore. Zvisinei, tsvakurudzo inoratidza kuti kuva necancer cachexia isingapindure, inova mhando yecancer isingapindure kana yarapwa, kunoderedza mikana yako yekupona cancer neinenge 30%.

Cancer cachexia inoitika nekuti chirwere ichi chinoita kuti metabolism yako ishandise simba rinobva muchikafu nekukurumidza kupfuura zvakajairika. Pamusoro pezvo, kenza nekurapa kenza zvinogona kukutadzisa kudya zvakanaka. Nekuda kweizvozvo, huremu hwako nehuremu hwetsandanyama zvinogona kudzikira zvakanyanya, zvichikanganisa chitarisiko chako (uye kuzviremekedza kwako), huwandu hwesimba rako, uye hupenyu hwako.

Kunyangwe pasina mushonga chaiwo wekurapa cancer cachexia, pane zvinhu zvaunogona kuita kuti ubatsire kudzora zviratidzo zvayo. Kana uri kusangana neizvi, bvunza timu yako yekutarisira cancer kuti ikubatsire. Vanonzwisisa matambudziko ekurarama necancer cachexia uye vachaita zvese zvavanogona kuti vakubatsire kudzora zviratidzo izvi.

Zvinhu zvakakosha zvekurangarira (Mharidzo Yekuenda Kumba)

• Cancer cachexia haisi chikamu chegomarara pachayo, asi chirwere chakasiyana chinofanira kugadziriswa. Kana iwe kana munhu waunoda ari kurasikirwa nehuremu, kushaya chido chekudya, kana kuneta zvakanyanya, taura nachiremba wako nezvazvo.
• Kudya zvekudya zvishoma, kakawanda zvine macalorie akawanda uye mapuroteni, uye kutsvaga mazano echiremba nezvekudya zvinovaka muviri zvinogona kubatsira kugadzirisa dambudziko iri.
• Hausi wega. Kune vanachiremba vekenza, vanamukoti, nyanzvi dzezvekudya, uye mapoka ekuchengetedza varwere vanorwara kuti vakubatsire parwendo urwu. Wana rutsigiro rwavo.
• Hutano hwepfungwa hwakakoshawo zvikuru. Pamwe chete nekuchinja kwemuviri, kuora mwoyo kunogonawo kuitika. Taura nechikwata chako chekurapa nezveizvi uwane rutsigiro rwunodiwa.

Kurwisa gomarara hakusi nyore. Zvakaoma kutsungirira mamwe matambudziko akaita seaya. Zvisinei, neruzivo rwakakodzera uye rutsigiro, matambudziko aya anogona kukundwa.

Cancer cachexia, kenza, kupera simba, kupera simba kwetsandanyama, kudya kunovaka muviri, anorexia, kurapwa kwekenza