Unogona kunge uri mushandi wekutakura zvinhu here? Ngatikurukurei nezve 'Kuongorora Vatakuri'!

Uri kuronga kutanga mhuri here? Kana kuti watove nemwana here? Saka unofanira kuziva nezvebvunzo iyi inonzi 'Carrier Screening'. Izvi zvinogona kukubatsira kuziva pachine nguva nezve mukana wekupa mwana wako zvimwe zvirwere zvenhaka kuburikidza newe. Ngatitaurei nezvazvo zvakadzama, handiti? Izvi zvichakubatsira kuita sarudzo dzakakosha nezvemhuri yako.

Chii chaizvo chinonzi 'mutakuri'?

Zvichitaurwa zviri nyore, 'mutakuri' munhu ane shanduko diki mujini , kana kuti ngatitii chirwere, mumuviri wako chine chekuita nechimwe chirwere. Asi zvinoshamisa kuti kazhinji, vatakuri ava havaratidzi zviratidzo zvechirwere. Chikonzero cheizvi ndechekuti tine makopi maviri ejini rega rega, rimwe kubva kuna amai vedu nerimwe kubva kuna baba vedu. Chinoitika kune mutakuri ndechekuti kunyangwe kopi imwe iine chikanganiso, imwe kopi ine hutano inodzivisa mhedzisiro yacho. Saka hausi kukura kwechirwere. Zvisinei, pane mukana wekuti mwana wako achapfuudza chikanganiso ichi chemajini, kunyanya kana mumwe wako ariwo mutakuri wechirwere chimwe chete.

Kana waita bvunzo iyi, mhedzisiro yacho inochengetwa yakavanzika muzvinyorwa zvako zvekurapwa. Hapana anogona kukupa ruzivo irworwo pasina mvumo yako. Zvakare, pamutemo, makambani einishuwarenzi yehutano kana waunoshandira havagone kukusarura nekuti mhedzisiro yebvunzo yemajini yakaita seiyi haina kujairika, kunyanya kana uine hutano hwakanaka.

Kuongororwa kwevana vane chirwere ichi kunowanzo shandiswa kuongorora zvirwere zve autosomal recessive . Izvi zvinganzwika seshoko resainzi, asi muchidimbu, kuti mwana awane chirwere ichi, vabereki vese vanofanira kunge vari ivo vanotakurwa nacho. Izvi zvinoreva kuti vabereki vese vanofanira kunge vaine kopi imwe chete yejini risina kunaka. Vanhu vazhinji havatombozivi kuti ndivo vanotakurwa nacho, nekuti hapana mumhuri mavo anogona kunge aine chirwere ichi.

Pamusoro pezvo, kunewo boka rezvirwere zvinonzi 'X-linked' . Izvi zvakabatana neX chromosome. Kazhinji, mukadzi (kazhinji XX) anogona kunge ari iye anotakura chirwere ichi. Asi kazhinji haaratidzi zviratidzo zvakawanda kana kuti haana. Izvi zvinokonzerwa nekuti ane maX chromosome maviri. Kana paine dambudziko nerimwe, rimwe ndiro rinoridzora. 'Fragile X syndrome' ndeimwe yezvirwere zvakaita se 'X-linked', uye inowanzo batanidzwa mu'Carrier Screening' panels.

Kuongorora uku kunoitwa riini?

Kana uri kufunga nezvekuva nemwana, zvakanaka kuti uite izvi 'Carrier Screening'. Kutaura zvazviri , zvakanaka kuti uite izvi bvunzo usati wabata pamuviri.Saka unogona kuziva pachine nguva kuti vana vako vemangwana vanogona kunge vaine chirwere chakasiyana chemajini. Paunoongororwa nenzira iyi, unowana nguva yekufunga nezvenzira dzakasiyana dzekutanga mhuri. Semuenzaniso:

• Kurera mwana (adoption) chiito chekurera mwana.
• Tava kushandisa nzira ye 'in vitro fertilization' (IVF - in vitro fertilization) uchishandisa mazai emupi kana mbeu yemurume.
• Kuongororwa kwemajini emwana asati aiswa muchibereko: Izvi zvinosanganisira kuyedza majini emazai emwana akagadzirwa nemazai emurume nemukadzi vasati vaiswa muchibereko chaamai.

Kana musingakwanise kuita izvi musati mabata pamuviri, chiremba wenyu anogona kukurudzirai kuti muongororwe chirwere chemwana wenyu panguva yekutanga yekuzvitakura . Kana maita bvunzo iyi panguva yekuzvitakura, munogona kuronga hutano hwenyu kwenguva yese yekuzvitakura kwenyu. Munogonawo kuda mimwe miedzo, yakaita seamniocentesis kana chorionic villus sampling (CVS) , kuti muone hutano hwemwana. Chiremba wenyu anogonawo kuronga chero zvinodiwa zvakakosha mwana wenyu angave nazvo mushure mekuzvarwa.

Ndiani anoda bvunzo iyi zvechokwadi?

Kutaura zvazviri, zano rakanaka kuti vaviri vari kufunga nezvekutanga mhuri vafunge nezvekuongororwa kwevana vane chirwere ichi. Kazhinji, zvakajairika kuti munhu ave nechirwere chemajini. Marudzi mazhinji ane mukana wekutakura chirwere chimwe chete.

Vanhu vanotevera kunyanya vanogona kunge vari panjodzi huru yekuva mutakuri wechirwere ichi:

• Kana mumwe munhu mumhuri (angave mwana wekare kana hama) aine chirwere chemajini, kungave chirwere che autosomal recessive kana chirwere che X-linked.
• Kana, kana mumwe munhu mumhuri achitozivikanwa kuti ane chirwere chemajini.

Ndiani anoita bvunzo idzi dzekuongorora hutachiona?

Unogona kuita bvunzo iyi ye'Carrier Screening' kuburikidza navanachiremba ava:

• Nyanzvi yezvekubereka.
• Mupi wezano wezvemajini kana nyanzvi yezvemajini.
• Chiremba wezvemadzimai uye chiremba wevakadzi (An OB/GYN).

Ndezvipi zvirwere zvinoongororwa nekuongorora chirwere chemukondombera?

Kuongororwa kwemuchina wekutakura chirwere kunowanzo tarisa mamwe mamiriro ezvinhu akajairika e autosomal recessive. Mamwe acho anosanganisira:

• Cystic fibrosis
• Fragile X syndrome (iyi inyaya ine chekuita neX)
• Chirwere cheSickle cell
• Chirwere cheTay-Sachs
• Thalassemia

Chii chinonzi Expanded Carrier Testing?

Kana uchida, unogona zvakare kuita 'expanded carrier testing' . Iyi bvunzo yezvirwere zvakasiyana-siyana kupfuura bvunzo shoma yambotaurwa. Iye zvino, vanachiremba vanowanzo kurudzira bvunzo iyi yakawedzerwa. Inogona kufukidza zvimwe zvirwere zvakawanda, pamwe makumi, pamusoro pezvirwere zvataurwa pamusoro apa. Heano mimwe mienzaniso:

• 'Congenital adrenal hyperplasia (CAH)' `(Congenital adrenal hyperplasia (CAH))`
• Kupera kwetsandanyama dzemusana
• Turner syndrome
• Chirwere cheWilson

Chii chinonzi Targeted Carrier Screening?

Fungidzira kuti kune zvimwe zvirwere zvemajini mumhuri yako. Kana zvakadaro, kana usingade kuita expanded carrier screening, unogona kuita 'targeted carrier screening' . Kureva kuti, tinongotsvaga zvirwere zviya zvine chekuita nemhuri yako.

Uyewo, mamwe matambudziko anogona kukanganisa vanhu vane madzitateguru akasiyana. Kana zvakadaro kwauri, chiremba wako anogona kukukurudzira kuti uongorore mamiriro acho ezvinhu chete.

Bvunzo iyi (Carrier Screening) inoitwa sei?

Kuongororwa kwevatachiona kunoda sampuli diki yeropa rako, mate, kana chipunu chepadama rako . Zvichienderana nezvaunoda, chiremba wako achasarudza imwe yenzira idzi:

• Kuongororwa kweropa.
• Kuyedzwa kwemate.
• Kutora tissue kubva mukati medama uchishandisa swab (Tissue test).

Unofanira kugadzirira izvi zvakananga here?

Kana uri kuongororwa mate kana kuti kuongororwa kwenyama, unogona kukumbirwa kuti urege kudya kana kunwa kwenguva pfupi usati waongororwa. Kunze kweizvozvo, hapana kugadzirira kwakakosha kunowanzo diwa kuti uongorore chirwere chako.

Chii chinoitika mushure mekuongororwa? Kana mhinduro dzagamuchirwa?

Chiremba wako achatumira ropa, mate, kana tissue kubva kwauri kuenda kuchipatara chekuongorora majini kuti zviongororwe. Zvichienderana nerudzi rwebvunzo yawakaita, uchawana mhinduro mumazuva mashoma kana mavhiki mashoma .

Mushure mekunge mawana zvabuda, chiremba wenyu anogona kukuendesai kuna chiremba wezvemajini . Ava vanhu vakadzidziswa zvakanyanya nezvemajini. Vanogona:

• Pindura mibvunzo yako yese nezvekuva mushandi wekutakura zvinhu.
• Kana muchida, ndapota ipai ruzivo rwakakosha kuti muzivise mhuri yenyu nezvemamiriro ekambani yenyu.
• Ipa ruzivo nezvesarudzo dzekuronga mhuri.
• Kukutumirai kune vamwe vanopa rubatsiro rwehutano kana zvichidikanwa.

Pane njodzi here nebvunzo iyi?

Paunotorwa ropa rako, unganzwa kurwadziwa zvishoma kana tsono yaiswa, kana kuti unganzwa kukuvadzwa zvishoma mushure mezvo. Izvi zvakajairika.

Usati waongororwa chirwere chako, taura nachiremba wako nezvemabhenefiti uye zvipingamupinyi zvebvunzo iyi. Semuenzaniso, pane mukana mudiki wekuti haungovi chete nechirwere ichi, asiwo unogona kunge uine chirwere chisina kusimba (izvi hazviwanzoitika). Vamwe vanhu vanogona kunzwa kushushikana kana kunetseka nezvekuongororwa uku. Taura nachiremba wako nezvekutya kwako uye zvinokunetsa. Tsvaga rubatsiro rwehutano hwepfungwa kana zvichidikanwa.

Mhedzisiro yacho inoti chii?

• Mhedzisiro isina kunaka: Izvi zvinoreva kuti bvunzo haina kuona chero mhando dzemajini dzinozivikanwa parizvino mumuviri wako. Panyaya iyi, njodzi yekuti vana vako vagare nhaka chirwere chemajini yakaderera zvikuru. Zvisinei, kuongororwa kwevana vanotakura chirwere hakugone kuona 100% yezvirwere zvese. Saka, mhedzisiro isina kunaka haivimbise kuti vana vako havazove nechirwere chemajini .

• Mhedzisiro yakanaka: Kana bvunzo yako yeCarrier Screening ikabuda nemhedzisiro yakanaka, zvinoreva kuti uri mutakuri weimwe kana akawanda ezvirwere zvemajini. Kana mhinduro dzako dziri dzakanaka, unofanira kufunga nezvekuti mumwe wako wekubereka aongororwewo .

Fungidzira kuti iwe nemumwe wako mese muri vanhu vane chirwere chimwe chete chinonzi autosomal recessive condition . Saka mwana wese wamuinaye ane mukana unotevera:

• Pane mukana we25% (mumwe chete pavana) wekugara nhaka majini ese akaremara (rimwe kubva kuna amai nerimwe kubva kuna baba) uye kuzvarwa uine chirwere ichi .
• Pane mukana we50% (mumwe chete pavaviri) wekugara nhaka jini rimwe chete risina kunaka (kubva kuna amai kana baba) uye kuva mutakuri wechirwere ichi . Asi mwana iyeye haazove nechirwere ichi.
• Pane mukana we25% (mumwe chete pavana) wekuwana majini ese ane hutano, asiri mutakuri kana kuti asina chirwere .

Zvinotora nguva yakareba sei kuti uzive mhedzisiro?

Kuongororwa kwemajini kunowanzo tora mazuva mashoma kusvika mavhiki mashoma kuti kupedzwe. Bvunza chiremba wako kuti ungatarisira riini mhinduro dzako.

Ndoona chiremba zvakare here?

Bata chiremba wako kana izvi zvikaitika:

• Kana musingawane mhedzisiro mukati menguva yamakabvumirana.
• Kunyangwe wakagamuchira mhinduro dzako, uchiri nemibvunzo nezvazvo.
• Kana uchida kutaura nezvesarudzo dzako dzekutanga mhuri.

Chekupedzisira, zvinhu zvinonyanya kukosha zvekurangarira

Saka, ndinovimba kuti ikozvino wava kunzwisisa zviri nani bvunzo iyi inonzi 'Carrier Screening'. Chinhu chikuru chauchawana kubva pane izvi ndechekuti uchapihwa simba rekuita sarudzo dzakangwara nezvemwana wako weramangwana. Zvakare, pamwe izvi zvichakubatsira kubvisa kutya nekusava nechokwadi kwaungave uinako uye kuwana rugare rwepfungwa .

Yeuka, usambozeza kutaura nachiremba wako, uye kana zvichidikanwa, nenyanzvi yezvemajini, kuti ungaenderera mberi sei nemhedzisiro iyi. Hutano hwepfungwa dzako hwakakoshawo, saka tsvaga rutsigiro rweizvozvo kana uchida. Izvi zvese ndezvekuchengetedza mhuri ine hutano uye inofara.

Kuongororwa kwevanotakura majini , kuongororwa kwevanotakura majini, zvirwere zvenhaka, kuongororwa kwemajini, pamuviri, kuronga mhuri, kupa mazano ezvemajini