Unogara uine nyota, uchiita weti nguva dzose? Iyi ndiyo Central Diabetes Insipidus (CDI) here? Ngatikurukurei!

Une manyoka anobuda mvura mukati mezuva here? Hazvina basa kuti unonwa mvura yakawanda sei, hazviitike here? Unofanirawo kumuka kakawanda here, dzimwe nguva husiku, kuti uite weti? Kunyangwe kana ukadaro, unobuda weti yakawanda ine ruvara rwakajeka here? Saka izvi zvingave zvakakosha kwauri. Tinodaidza chirwere ichi kuti Central Diabetes Insipidus, kana kuti `Central Diabetes Insipidus (CDI)`. Kunyangwe chine "chirwere cheshuga" muzita racho, ichi hachisi chirwere cheshuga chatinoziva tese. Ngatitaurei nezvazvo zvakadzama.

Chii chinonzi Central Diabetes Insipidus (CDI)?

Zvichitaurwa zviri nyore, `Central Diabetes Insipidus (CDI)` chirwere chisingawanzoitiki. Chinoitika ndechekuti muviri wako hauna Antidiuretic Hormone (ADH) yakakwana, dzimwe nguva inonzi Vasopressin . Iyi ADH hormone inobatsira kudzora huwandu hwemvura mumiviri yedu. Kana iyi hormone yaderera, itsvo dzinotanga kuburitsa mvura yakawanda seweti. Saka, unoweta zvakanyanya uye unonzwa kuzvimba zvakanyanya.

Homoni iyi yeADH inogadzirwa nehypothalamus iri muuropi hwedu. Zvisinei, inochengetwa uye inoburitswa kana ichidiwa neimwe gland diki iri muuropi , pituitary gland . Saka, kana paine kukuvara kwehypothalamus kana pituitary gland, CDI inogona kukura.

Kana uine CDI, kana ukasanwa mvura yakakwana yekutsiva huwandu hwemvura yaunorasikirwa nayo kuburikidza neweti, unogona kupera mvura mumuviri . Izvi zvine njodzi huru.

Vamwe vanhu vanogona kunge vaine rudzi rwakanyanya rweCDI, zvichireva kuti hormone yeADH haisi kushanda nemazvo. Izvi zvinonzi `complete CDI`. Vamwe vanogona kunge vaine rudzi rwakati kurei, zvichireva kuti hormone yeADH iri kushanda kusvika pamwero wakati. Izvi zvinonzi `partial CDI`.

Chinhu chinonyanya kukosha ndechekuti, kana ukanzwa zita rekuti `Diabetes Insipidus`, usarisanganise nerinonzi `Diabetes Mellitus`. Matambudziko ese aya ane izwi rekuti `diabetes` nekuti ese ari maviri aya ane zviratidzo zvakafanana zvenyota yakawandisa uye kuita weti kakawanda. Izwi rekuti `diabetes` rinobva pashoko rechiGiriki rekuti `diabainein`. Rinoreva `kupfuura nemu`. Sezvinongoita mvura inopfuura nemumuviri nekukurumidza yobuda muweti.

Kune mhando huru ina dzechirwere cheshuga chinonzi insipidus:

• `Central Diabetes Insipidus (CDI)` - Iyi ndiyo mhando inonyanya kuzivikanwa yatiri kutaura nezvayo.
• Nephrogen Diabetes Insipidus - Itsvo hadzipindure kuADH.
• `Dipsogenic Diabetes Insipidus` - Nekuda kwechido chepfungwa chekuda kunwa mvura yakawandisa.
• `Gestational Diabetes Insipidus` - Chirwere chenguva pfupi chinoitika panguva yekuzvitakura.

Chii chinonzi ADH (hormone inorwisa diuretic)?

ADH, kana kuti vasopressin, sezvambotaurwa, ihormone inogadzirwa nehypothalamus yako uye inochengetwa nekuburitswa negland rako repituitary .Vakaita semakemikoro anoronga mabasa akasiyana-siyana emiviri yedu. Ava vanofamba neropa uye vanoendesa mashoko kunhengo dzedu, tsandanyama, nedzimwe nhengo dzemuviri. Zviratidzo izvi zvinoudza muviri zvekuita uye nguva yekuzviita.

Hypothalamus chikamu cheuropi hwedu chinodzora mashandiro ehurongwa hwetsinga hwemuviri hwemuviri negland repituitary. Inogadzira ADH uye inoitumira kugland repituitary kuti ichengete uye ibudise kana zvichidikanwa.

Gland repituitary igland diki riri pasi pehuropi, pasi pehypothalamus. Iro chikamu chehurongwa hwedu hwe endocrine. Basa raro nderekugadzira, kuchengeta, uye kuburitsa mahormone akawanda akakosha. ADH inochengetwa uye inoburitswa negland repituitary rekumashure.

ADH inonyanya kudzora huwandu hwemvura inotorwa neitsvo dzedu mumuviri wedu kana dzichisefa tsvina kubva muropa redu, zvichiita kuti mvura irambe yakaenzana mumuviri. Kazhinji, kana usina mvura yakakwana kana kuti BP yako yakaderera, muviri wako unogadzira uye unoburitsa ADH yakawanda. Izvi zvinopa itsvo chiratidzo chekuti "dzichengete mvura mumuviri wako, kwete kuiburitsa muweti."

Saka, muCDI, hypothalamus haibudisi ADH yakakwana, kana kuti pituitary gland haibudisi ADH yakakwana. Ndosaka paine weti yakawanda kakawanda.

Ndeupi musiyano uripo pakati peCentral Diabetes Insipidus (CDI) neNephrogen Diabetes Insipidus?

Zviratidzo zvezvirwere zvese izvi zvakafanana: kuita weti yakawandisa uye kunwa mvura yakawandisa. Musiyano uripo pane chinokonzera uye kurapwa kwezvirwere izvi zviviri.

Chirwere cheshuga cheNephrogen Insipidus chinoitika kana pituitary gland yako yaburitsa ADH yakakwana, asi itsvo dzako hadzina kupindura zvakanaka. Izvi zvinoreva kuti itsvo dzako hadzigone kuchengeta mvura. Pane zvikonzero zvakati wandei zveizvi:

• Mimwe mishonga, semuenzaniso lithium netetracycline .
• Kuderera kwepotassium muropa (Hypokalemia) .
• Kuwedzera kwecalcium muropa (Hypercalcemia) .
• Kuvharika kwenzira yeweti.

Central Diabetes Insipidus (CDI) inokonzerwa nekusashanda zvakanaka kwehypothalamus kana pituitary gland, iyo isingaburitse ADH yakakwana. Inowanzo kukonzerwa nekukuvadzwa kwehypothalamus kana pituitary gland. Kukuvadzwa uku kunogona kukonzerwa nezvinhu zvakaita sekukuvara mumusoro, kuvhiyiwa, kuzvimba, kana bundu.

Ndiani anowana CDI? Yakajairika zvakadii?

Chirwere cheshuga cheCentral Diabetes Insipidus (CDI) chinogona kukura chero pazera ripi zvaro, asi chinowanzoitika pakati pemakore gumi kusvika makumi maviri .

CDI chirwere chisingawanzoitiki, chinobata munhu mumwe chete pavanhu 25,000 .

Ndezvipi zviratidzo zveCDI?

Zviratidzo zvikuru zve "Central Diabetes Insipidus" (CDI) ndeizvi:

• Kuita weti kakawanda, kunyangwe husiku.
• Kuburitsa weti yakawanda yakajeka kana kuti yakajeka nguva imwe neimwe.
• Kunzwa kuneta zvakanyanya uye nyota , saka inwa mvura nguva nenguva.

Kunyange zvazvo munhu akajairwa achiburitsa weti inosvika marita rimwe kusvika maviri pazuva, munhu ane CDI anogona kuburitsa weti inosvika marita gumi nemapfumbamwe (20 quarts) pazuva ! Fungidzira kuti yakawanda sei!

Zviratidzo muvana vacheche

Vana vacheche vane CDI vanogonawo kuratidza zviratidzo zvakaita seizvi:

• Kusagadzikana nguva dzose uye kushatirwa.
• Kuneta, hope.
• Kurutsa.
• Kuzvimba.
• Kupindwa nechando.

Zviratidzo zvekushaya mvura mumuviri

Kana CDI ikasarapwa, kana munhu ane CDI akasanwa mvura yakakwana, kupera mvura mumuviri kunogona kukurumidza kuitika. Zviratidzo zvekupera mvura mumuviri zvinosanganisira:

• Kunzwa dzungu, kunzwa kunyara.
• Ndaneta.
• Muromo wakaoma, miromo, maziso.
• Kuomerwa nekuita mabasa epfungwa ari nyore.
• Kusvotwa.
• Kufenda.

Kana uine nyota yakawandisa uye uchiita weti kakawanda uye/kana zviratidzo zvekusashanda zvakanaka mumuviri, zvakakosha kuti uende kuchipatara nekukurumidza. Kunyangwe CDI isingawanzoitiki, haisiriyo yega chirwere chinogona kukonzera zviratidzo izvi. Nyota yakawandisa uye kuita weti kakawanda zviratidzo zvakasimba zvekuti chimwe chinhu hachisi kushanda zvakanaka mumuviri wako uye kuti unoda rubatsiro rwechiremba.

Ndezvipi zvinokonzera chirwere cheCentral Diabetes Insipidus (CDI)?

Chikonzero chikuru cheCentral Diabetes Insipidus (CDI) kushomeka kwehomoni yeADH zvachose kana kuti chikamu chayo. Kushomeka uku kunowanzo kukonzerwa nekukuvara kwehypothalamus yako, pituitary gland, kana tishu inobatanidza zviviri izvi (pituitary stem). Zvimwe zvikonzero zvinosanganisira:

• Kukuvadzwa kwehypothalamus kana pituitary gland nekuda kwekuvhiyiwa.
• Kukuvadzwa kwe hypothalamus kana pituitary gland nekuda kwekukuvara kwemusoro, kunyanya kutyoka kwemusoro webasal skull.
• Kuzvimba (granulomas) kunokonzerwa nezvirwere zvakaita se sarcoidosis kana TB .
• Mamota akadai se craniopharyngioma kana germinoma .
• Langerhans cell histiocytosis (ichi chirwere chisingawanzoitiki chinogona kukonzera kukuvara kwenyama kana mavanga munzvimbo imwe kana kupfuura mumuviri).
• Kuchinja kwemajini kwakagara nhaka pachromosome 20 (izvi hazviwanzoitiki - nyaya dzinosvika zana dzakataurwa mumabhuku ekurapa).

Muchikamu chimwe muzvitatu chezvirwere zveCDI, vanachiremba havakwanise kuwana chikonzero chaicho. Izvi zvinonzi idiopathic central diabetes insipidus (CDI).Vaongorori vanofunga kuti dzimwe nyaya dzeCDI dzinokonzerwa nehutachiona hwemuviri (idiopathic CDI) dzinogona kukonzerwa nezvinhu zvinodzivirira muviri kuti usashande zvakanaka. Mumamiriro ezvinhu ekudzivirira muviri, masoja emuviri wako anotanga kurwisa nyama ine hutano. Muchiitiko ichi, masoja emuviri anogona kugadzira masoja ekudzivirira muviri, kana kuti malymphocyte, anorwisa masero anogadzira ADH.

CDI inogonawo kuitika sechikamu chechirwere chikuru kana chirwere, chakadai seWolfram syndrome ( chirwere chenhaka) uye septo-optic dysplasia (chirwere chisingawanzoitiki chekukura kwehuropi pakutanga).

Unoziva sei kana uine chirwere cheCDI? (Kuongororwa)

Nekuti nyota yenguva dzose uye weti zvinogonawo kukonzerwa nezvimwe zvirwere, zvakaita sechirwere cheshuga, zvakakosha kubvisa zvimwe zvirwere pakuongorora chirwere cheshuga chinonzi central diabetes insipidus (CDI). Saka, kana uine zviratidzo izvi, chiremba wako anogona kuita bvunzo dzinoverengeka.

Kuongorora chirwere cheCDI kunosanganisirawo kuziva kuti chii chinokonzera chirwere ichi.

Ndezvipi zviedzo zvinoshandiswa kuongorora chirwere cheCDI?

Kuongororwa kwekushaya mvura ndiyo nzira iri nyore uye yakavimbika yekuongorora chirwere cheCDI. Kana chiremba wako akarayira bvunzo iyi, achava nechokwadi chekuti unotariswa zvakanyanya panguva yekuongororwa, sezvo zvinogona kukonzera kupera mvura mumuviri.

Kuongororwa uku kunosanganisira kugara usina mvura kwemaawa akati wandei uye kuona kuti muviri wako unopindura sei. Kana uine CDI, ucharamba uchibuda weti yakawanda ine mvura (dilute), ine ruvara rwakajeka, kunyangwe kana uchiwanzobuda weti shoma yero yakasviba, yakabatana.

Chiremba wako anogonawo kuraira bvunzo idzi kuti abatsire kuongorora CDI uye kubvisa zvimwe zvirwere:

• Kuongororwa kweropa kuti uone huwandu hweADH (antidiuretic hormone) muropa.
• Kuongororwa ropa kuti uone huwandu hweshuga mumuviri kuti uonekwe kuti hapana chirwere cheshuga.
• Kuongororwa kweweti kuti uone huwandu hweweti (osmolality) uye/kana kuti uone ma ketones, izvo zvinogona kuratidza chirwere cheshuga.
• Kuti uone kuti itsvo dzako dziri kupindura sei, uchapihwa jekiseni reADH yakagadzirwa. Vanhu vane Nephrogenic Diabetes Insipidus havapinduri neADH yakagadzirwa nekuti itsvo dzavo hadzina simba reADH. Kune rumwe rutivi, vanhu vane CDI vanopindura neADH yakagadzirwa.
• Miedzo yekufungidzira yakaita seMRI (Magnetic Resonance Imaging) inogona kushandiswa kuona kana pituitary gland yako kana hypothalamus yakakuvara, uye kana zvakadaro, chikonzero chacho chii.

Ndezvipi zvirongwa zvekurapa CDI?

Kurapwa kweCDI kunoenderana nekuoma kwekushomeka kwehomoni yeADH.

Une CDI yakakwana.Kana zvakadaro, desmopressin ndiyo mushonga wekutanga. Uyu mushonga unoshanda sehomoni inonzi ADH. Unogona kutora desmopressin sejekiseni, sepiritsi, kana sepfapfaidzo yemhino.

Kana uine chikamu cheCDI , zvichireva kuti natural ADH ichiri kushanda kusvika pamwero wakati, chiremba wako anogona kukupa mimwe mishonga, yakaita sehydrochlorothiazide (HCTZ) .

Sekurapa vacheche vadiki vane CDI, mukaka wemukaka kana wezamu wakasanganiswa nemvura wopihwa pamwe chete nehydrochlorothiazide unogona kupihwa.

Pane mimwe migumisiro yakaipa yeDesmopressin here?

Desmopressin mushonga wakachengeteka zvikuru une migumisiro mishoma. Migumisiro inogona kunge iri:

• Musoro.
• Kurwadziwa kwemudumbu.
• Kusvotwa.
• Mhino dzakazadzwa kana kuti mhino inoyerera.
• Kubuda ropa mumhino.

Kana ukanwa desmopressin yakawandisa, kana ukanwa mvura yakawandisa paunenge uchiinwa, muviri wako unogona kuchengeta mvura yakawandisa. Izvi zvinogona kukonzera zviratidzo zvakaita se:

• Musoro.
• Dzungu.
• Kuzvimba.
• Kuwanda kwemunyu (sodium) muropa (Hyponatremia) .

Zviratidzo zveHyponatremia:

• Musoro wakakomba kana kuti unotora nguva refu.
• Kuvhiringidzika.
• Kusvotwa nekurutsa.

Kana uine zviratidzo zvekushaya simba kweropa, unofanira kufonera 911 kana kuenda kuchipatara che emergency chiri pedyo nekukurumidza.

Munhu ane CDI angazvigadzirisa sei izvi?

Kana uine chirwere cheCDI, pamusoro pekurapwa, zvakakosha zvikuru kunwa mvura nguva dzose kuti usapere mvura mumuviri.

Zvakakoshawo kuona chiremba wako nguva nenguva kuti uve nechokwadi chekuti kurapwa kwako kuri kushanda nemazvo uye kuti mushonga wakanyorwa wakarurama.

Ndezvipi zvinhu zvinokonzera njodzi yekuva neCDI?

Zvinosuwisa kuti nyaya zhinji dzeCentral Diabetes Insipidus (CDI) hadzigone kudzivirirwa. Zvinhu zvinokonzera njodzi yekuva neCDI zvinosanganisira:

• Kuvhiyiwa kwehuropi.
• Kuva nenhoroondo yemhuri yechirwere cheshuga insipidus uye/kana Wolfram syndrome.
• Kukuvara mumusoro.
• Utachiona hwehuropi.

Utano hwemunhu ane chirwere cheCDI hwakaita sei? (Kufungidzira)

Kufungidzira kwemunhu ane `Central Diabetes Insipidus (CDI)` kwakanaka, uye kana ikarapwa zvakanaka uye ikanwiwa mvura yakakwana, hazvikonzeri matambudziko makuru.

Zvisinei, vana vadiki, vakwegura, neavo vane matambudziko ehutano hwepfungwa vari panjodzi huru yematambudziko nerufu nekuti vanogona kunetseka kuziva nyota yavo kana kutora matanho.

Ndezvipi zvinetso zvinogona kuitika nekuda kwechirwere cheshuga cheCentral Diabetes Insipidus (CDI)?

Dambudziko guru reCDI nderekutiKushaya mvura mumuviri . Izvi zvinoreva kuti muviri wako uri kurasikirwa nemvura yakakwana uye ma electrolytes kuti ushande zvakanaka. Kana uine CDI, unogona kudzora huwandu hwakawanda hwemvura yaunorasikirwa nayo muweti yako nekunwa mvura yakawanda. Asi kana usina, unogona kukurumidza kupera mvura mumuviri.

Kushaya mvura mumuviri kune njodzi, kunyange kutouraya. Kana uine zviratidzo zvekupererwa nemvura mumuviri, zvakaita sedzungu, kuda kurutsa, uye kuneta, enda kuchipatara chiri pedyo nekukurumidza.

Kana CDI muvana vadiki ikasarapwa , kupera mvura mumuviri kakawanda kunogona kukonzera matambudziko akadai se:

• Kubatwa nepfari.
• Kukuvara kwehuropi.
• Kunonoka kukura kwemwana.
• Kukura kwakanonoka.

Kana CDI ikasiyiwa isina kurapwa muvana nevakuru, matambudziko akadai se:

• Kurova kwemoyo kusina kurongeka (Arrhythmia) .
• Kupindwa nechando.
• Kuoma kweganda nemukati memucous (semuenzaniso mukati memuromo, mhino).
• Kubatwa nepfari.
• Kushaya simba.

Vakuru vane CDI vanogona kuva nechirwere chinonzi orthostatic hypotension , chinova kudzikira kweBP kamwe kamwe kana vakamira kana vakagara. Izvi zvinogona kukonzera dzungu kana kurasikirwa nepfungwa kwenguva pfupi.

Unofanira kuona chiremba rini?

Kana uine chirwere cheCentral Diabetes Insipidus (CDI), zvakakosha kuti ugare uchiona chiremba wako kuti utarise mamiriro ako uye uve nechokwadi chekuti kurapwa kwako kuri kushanda. Kana uine zviratidzo zvinokunetsa, iva nechokwadi chekuzivisa chiremba wako.

Kana uine zviratidzo zvekupererwa nemvura zvakanyanya, zvakaita sekuvhiringidzika kana kuda kurutsa, enda kuchipatara che emergency chiri pedyo nekukurumidza.

Mibvunzo yekubvunza chiremba wako

Kana wakamboonekwa uine chirwere cheCentral Diabetes Insipidus (CDI), zvingabatsira kubvunza chiremba wako mibvunzo iyi:

• Sei ndakagadzira CDI?
• Dambudziko rangu reCDI nderechigarire here kana kuti nderenguva pfupi?
• Ndedzipi nzira dzekurapa dzandinadzo?
• Ndezvipi zvakanakira nezvakaipa zvesarudzo dzakasiyana dzekurapa?
• Ndinofanira kunwa mvura yakawanda sei pazuva?
• Chii chimwe chandingaita kuti ndigadzirise dambudziko rangu?
• Nhengo dzemhuri yangu dziri panjodzi yekubatwa nechirwere cheCDI here?

Chekupedzisira, chinhu chinonyanya kukosha (Mharidzo Yekuenda Kumba)

Chirwere cheCentral Diabetes Insipidus (CDI) chirwere chisingawanzoitiki asi chinogona kunge chakakomba. Mashoko akanaka ndeekuti chinogona kurapwa uye kutarisirwa.Kana uine chirwere cheCDI, zvakakosha kuti ugare uchiona chiremba wako kuti uve nechokwadi chekuti kurapwa kwako kuri kushanda nemazvo. Kana uine mibvunzo nezvechirwere chako, usatya kubvunza chiremba wako. Varipo kuti vakubatsire kugadzirisa chirwere chako. Usakanganwa kunwa mvura yakawanda, zvakakosha zvikuru!

` Chirwere cheshuga chepakati Insipidus, CDI, ADH, itsvo, mahormone, weti yakawandisa, nyota yakawandisa