Pane nzvimbo isinganzwisisike paganda rako here? Inogona kunge iri DFSP (Dermatofibrosarcoma Protuberans)!

Wakamboona bundu diki kana kuchinja ruvara paganda rako here? Dzimwe nguva hatinyatsoritarisiri, handiti? Asi dzimwe nguva kunyange chinhu chidiki seichi chinogona kuva chinhu chekufunga nezvacho. Nhasi, tichataura nezverudzi rwekenza yeganda rusingawanzoitiki asi rwakakosha. Inonzi Dermatofibrosarcoma Protuberans , kana kuti DFSP muchidimbu.

Chii chinonzi Dermatofibrosarcoma Protuberans (DFSP)?

Zvichitaurwa zviri nyore, DFSP igomarara reganda rinokura zvishoma nezvishoma, asi risingawanzoitiki. Rinotanga pakati peganda redu, dermis . Unogona kunzwawo chiremba achiti DFSP.

Nekuti iyi igomarara rinokura zvishoma nezvishoma, hariwanzopararira kune dzimwe nhengo dzemuviri. Zvisinei, hazvina kunaka kuifuratira. Zvakakosha kuwana kurapwa kwakakodzera uye kubvisa bundu iri. Ipapo chete ndipo panogona kudzivirirwa kenza kuti isadzoke (kudzoka) kana kupararira kune dzimwe nhengo dzemuviri (kenza inopararira). Nekurapwa kwakakodzera, munhu ane DFSP ane mukana wakanaka wekupora.

DFSP iyi ingori bundu here? Kana kuti kenza?

Kwete, DFSP haisi bundu risina njodzi chete. Idambudziko rinotyisa . Kutaura chokwadi, imhando yegomarara renyama yakapfava, rudzi rwesarcoma yenyama yakapfava . Sarcomas igomarara rinoumbwa munzvimbo dzakadai setsandanyama, mafuta, uye ganda. Dzimwe nguva, rinogonawo kukanganisa mapfupa.

Ko DFSP inogona kupararira (metastasize) kune dzimwe nhengo dzemuviri here?

DFSP haisi mhando yekenza inopararira nekukurumidza mumuviri wese. Zvisinei, kashoma, munhu mumwe chete pavanhu makumi maviri vane DFSP anogona kupararira kupfuura payakatanga. Iyi inonzi metastatic cancer .

Izvi zvingangopararira kana zvikasarapwa, kana kuti kenza yapararira zvakanyanya muganda, munyama ine mafuta netsandanyama.

Chimwe chinhu ndechekuti, kunyange hazvo chikonzero chaicho chisingazivikanwi, kana DFSP ikaitika panguva yekuzvitakura, inogona kuwedzera kuipa.

Uyewo, vanhu vashoma vane DFSP vanogona kukura nerudzi rwe fibrosarcomatous dermatofibrosarcoma protuberans (DFSP-FS) rwakasimba uye runokurumidza kupararira. Kunyangwe kana mabundu aya eDFSP-FS akabviswa nekuvhiyiwa, ane mukana wekudzoka uye anogona kupararira kune dzimwe nzvimbo.

Dambudziko iri rinonzi DFSP rakajairika zvakadii?

DFSP rudzi rwegomarara rusingawanzoitiki. Pasi rose, rinongobata vanhu vana chete pavanhu miriyoni pagore. DFSP inoumba pakati pe1% ne6% yemasero ese egomarara akapfava.

Gomarara iri rinonyanya kuwanikwa muvanhu vakuru vane makore ari pakati pe20 ne50. Zvisinei, vana vadiki vanogonawo kuwana gomarara iri reganda. Vamwe vacheche vanogona kuva neDFSP pakuzvarwa. Tsvagiridzo yakaratidza kuti vanhu vatema vane mukana wekuwana gomarara iri kupfuura vanhu vemamwe marudzi.

Ndedzipi mhando huru dzeDFSPs?

Vanachiremba vanoongorora nyama yemuviri vachishandisa maikorosikopu, vanogona kukuudza rudzi rweDFSP yaunayo nekuongorora masero. Kune mhando dzakawanda huru:

• Matumbu eBednar (anozivikanwawo seDFSP ine pigmented): Marudzi aya emasero ane melanin yakawanda, iyo pigment inoita kuti ganda rive neruvara rwaro. Ndosaka matumbu aya achigona kuonekwa mumavara akasiyana-siyana, anosanganisira matsvuku, mashava, bhuruu, uye tsvuku. Rudzi urwu runotora chikamu chinosvika 5% chezvirwere zveDFSP.
• Giant cell fibroblastoma: Rudzi urwu runoratidzwa nekuvapo kwemasero makuru. Rudzi urwu runonziwo juvenile DFSP nekuti runowanzoitika muvana nevechidiki.
• Fibrosarcomatous dermatofibrosarcoma protuberans (DFSP-FS): Sezvambotaurwa, iyi imhando yesarcoma yakapfava ine simba uye inopararira nekukurumidza.
• Myxoid DFSPs: Idzi dzakagadzirwa nerudzi rusina kujairika rwe connective tissue inonzi myxoid stroma. Rudzi urwu rweDFSP haruwanzoitiki.

Chii chinokonzera DFSP?

Zvinoshamisa kuti vanhu 9 pa10 vanowana DFSP vane genetic mutation inokonzera chirwere ichi . Kuchinja kwemajini uku kunoitika mumasero edu mushure mekuzvarwa kwedu. Izvi zvinoreva kuti DFSP haina kukonzerwa nehurema hwemajini hwakagara nhaka kubva kuvabereki vedu.

Ndezvipi zvinhu zvinokonzera njodzi pakugadzira DFSP?

Pamusoro perudzi, kuva nechero rudzi rwekukuvara kweganda kana mavanga kunogona kuwedzera njodzi yekubatwa neDFSP. Kune nzira dzakasiyana siyana dzingakuvara ganda:

• Kupisa
• Ndiri kurapwa nemwaranzi
• Kuchekwa kwepamuviri
• Matattoo

Fungidzira, wakambotsva zvakanyanya uye wakambova nevanga guru. Kana kuti, wakamborapwa nemwaranzi yechimwe chirwere. Kana ganda rikakuvadzwa nezvinhu zvakaita seizvi, pane mukana mudiki wekuti chirwere chakadai seDFSP chizoitika mune ramangwana, kunyange hazvo zvisingawanzoitiki. Ndosaka tichifanira kugara tichiziva nezvekuchinja kweganda.

Ndezvipi zviratidzo zveDFSP?

Zviratidzo zvekutanga zveDFSP hazvinyatsooneki zvekuti tinogona kusazviona kana kutozviona. Mabundu aya anowanzoonekwa pachipfuva, kumusana, pamafudzi, mudumbu, kana pamagaro. Anogonawo kuonekwa pamaoko, makumbo, mumusoro, uye mukati memuromo.

Pakutanga, unogona kuona nzvimbo diki yakaita semavanga paganda.Yakati sandara uye hairwadzi. Inganzwa kunge yakaoma zvishoma kana ikaibata, uye ruvara rwayo runogona kuchinja zvishoma.

Muvana vacheche nevana vadiki, DFSP inogona kutaridzika sechiratidzo chekuzvarwa . Mavara aya anowanzova nehupamhi hweinji imwe kusvika mashanu (1 kusvika 5 centimeter).

Zviratidzo zveDFSP zvinoonekwa kana kenza ichikura. Sezvo bundu richikura, rinopinda muchikamu chepamusoro cheganda (epidermis). Izvi zvinoita kuti mapundu akaomarara (nodules) aoneke pamusoro peganda . Izwi rekuti "protuberance" rinoreva "kubuda."

Unogona kuona zviratidzo izvi muzviputi izvi:

• Inogona kutsemuka kana kubuda ropa zviri nyore.
• Yakabatana zvakasimba neganda (haigone kufambiswa).
• Sezvaunokura, ganda rako rinotambanuka.
• Zvinonzwa zvakaoma kana zvikabatwa, kana kuti serabha.
• Ruvara runogona kuva rutsvuku-shava, pepuru, bhuruu, kana rutsvuku.
• Ingave inonyorova zvishoma kana yabatwa.

Pane zvimwe zvirwere zvinokonzera zviratidzo zvakafanana neDFSP here?

Ehe, pane chirwere cheganda chisiri chegomarara chinonzi cellular dermatofibroma . Izvi zvinogona kutaridzika zvakafanana neDFSP, kunyanya pakutanga kwacho. Cellular dermatofibromas mabundu asina njodzi munyama. Anowanzoonekwa pamakumbo. Dzimwe nguva anogona kuvaviwa uye kurwadza. Mazhinji edermatofibromas haadi kurapwa. Zvisinei, kuchenjera kusavhiringidza zviviri izvi, saka kuchenjera kuona chiremba kana ukaona chimwe chinhu chitsva paganda rako.

Chirwere cheDFSP (Dermatofibrosarcoma Protuberans) chinoonekwa sei?

DFSP inoongororwa navanachiremba veganda , avo vari vanachiremba vane hunyanzvi hwekurapa kenza yeganda nezvirwere zveganda. Chiremba wako anotanga atora sampuli diki yebundu reganda kana gwapa racho oritumira kurabhoritari kuti riongororwe (biopsy yeganda) . Bundu rese rinogona kubviswa roendeswa kurabhoritari. Vanachiremba vezvirwere vachazotarisa nyama yacho nemaikorosikopu kuti vaone kana ine masero ekenza.

Kana biopsy yeganda ikaratidza kuti une DFSP, unogona kukumbirwa kuti uitwe MRI scan . Izvi zvichabatsira kuona saizi chaiyo yebundu uye kuti rakapararira zvakadii muganda. Ruzivo urwu rwakakosha zvikuru pakuronga kurapwa.

Ndeapi marapirwo eDFSP (Dermatofibrosarcoma Protuberans)?

Kurapa kukuru uye kwakanakisa kweDFSP kubvisa bundu nekuvhiyiwa. Vanachiremba veganda vanowanzo shandisa nzira yakakosha inonzi Mohs surgery kubvisa bundu reDFSP. Hezvino zvinoitika panguva yekuvhiyiwa uku:

• Kutanga, mushonga unonyaradza marwadzo unopinzwa munzvimbo yekurapwa, saka hauzonzwi kurwadziwa.
• Zvadaro, chiremba anocheka bundu regomarara oribvisa. Asi kwete bundu chete, asiwo nzvimbo diki yeganda rine hutano rakaripoteredza. Izvi zvinonzi margin .
• Zvadaro, mipendero (miganhu) yenyama yakabviswa inoongororwa nemaikorosikopu kuti vaone kana paine masero ekenza aripo.
• Kana kuchine masero ekenza kumucheto, chiremba achabvisa mamwe matishu kubva panzvimbo yakaitirwa kuvhiyiwa zvakare.
• Nenzira iyi, kubviswa kwenyama kunoenderera mberi kusvika pasina masero ekenza awanikwa pamucheto.
• Kana kenza yabviswa zvachose, kuvhiyiwa kwekuvakazve kunoitwa kana zvichidikanwa.

Pane mimwe mishonga yekurapa DFSP pasina kuvhiyiwa here?

Kunyangwe kana bundu reDFSP rikabviswa nekuvhiyiwa, dzimwe nguva rinogona kudzoka. Mushure mekuchekwa kwakajairwa, pane mukana we20% kusvika 30% wekuti richadzoka mukati memakore matatu. Mushure mekuvhiyiwa kwaMohs, njodzi iyi inoderedzwa kusvika 4% kusvika 5%. Zvisinei, zvakakosha kuramba wakangwarira, sezvo bundu rinogona kudzoka kunyangwe mushure memakore gumi kana kupfuura.

Dzimwe nguva, kana kenza yapararira kune dzimwe nhengo dzemuviri (metastatic DFSP), kana bundu racho rakakura zvakanyanya kana kuti riri munzvimbo yaro zvekuti haribviswe nekuvhiyiwa, vanachiremba vanoshandisa mushonga unonzi Imatinib . Mushonga uyu unogona zvakare kuderedza bundu, zvichiita kuti zvive nyore kubvisa nekuvhiyiwa.

Uyewo, kana kuvhiyiwa kusingakwanise kubvisa kenza zvachose, kana kuti kana kuvhiyiwa kusingagoneke zvachose, kurapwa nemwaranzi kunogona kushandiswa.

Chii chiri tarisiro yemunhu ane DFSP?

Aya mashoko anonyaradza zvechokwadi. Sezvo DFSP iri kenza inokura zvishoma nezvishoma, isingachanyanyi kurwara, kana ikarapwa nemazvo, vanhu vanopfuura 99% vanorarama kwemakore gumi kana kupfuura. Saka, chinhu chakakosha ndechekusatya uye kutevedzera zano rachiremba wako.

Ndingaitei kuti ndivandudze maonero angu?

Pane zvinhu zvakawanda zvaunogona kuita kuti uvandudze maonero ako:

• Gara uchizviongorora ganda rako. Tarisa kana paine shanduko itsva, mavanga, kana mapundu paganda rako. Kana ukaona chimwe chinhu, taurira chiremba wako nekukasika.
• Mushure mekurapwa, endai kuna chiremba wenyu kuti anoongororwa ganda renyu kanenge mwedzi mitatu kusvika mitanhatu yega yega kwemakore matatu ekutanga. Wobva waenda kunoongororwa kamwe chete pagore, kana sekurairwa nachiremba wenyu.
• Deredza kupiswa nezuva. Mwaranzi yeUV inobva kuzuva inowedzera njodzi yekubatwa nekenza yeganda. Saka, pfeka mafuta ekudzivirira zuva paunobuda muzuva, pfeka mbatya dzinodzivirira , uye deredza nguva yako panze panguva inopisa yezuva.

Ndinofanira kuona chiremba rini?

Kana ukaona shanduko itsva paganda rako, kunyanya kana uine chimwe chezvinotevera, iva nechokwadi chekuona chiremba:

• Mapundu matsva, anoramba aripo kana kuti mavanga matsva, kana kuti ganda idzva rinokura.
• Kuchinja kwemapundu, mavanga ekuzvarwa, mavanga ekare, kana matattoo.
• Kana mapundu ari paganda achibuda ropa zviri nyore.

Yeuka kuti kuchinja kweganda kazhinji hakukuvadzi. Zvisinei, dzimwe shanduko dzinogona kuva chiratidzo chegomarara reganda. Saka, kana uine kusava nechokwadi, zvakanaka kuona chiremba kuti agadzirise dambudziko racho.

Chii chandinofanira kubvunza chiremba wangu?

Kana ukaonekwa uine DFSP, ungangoda kubvunza chiremba wako mibvunzo yakaita seiyi:

• Sei ndakawana kenza yeganda iyi?
• Ndiri panjodzi yekubatwa nedzimwe mhando dzekenza yeganda here?
• Ndeipi nzira yakanakisisa yekurapa?
• Pane njodzi yekuti gomarara iri ripararire kune dzimwe nhengo dzemuviri here?
• Ndinofanira kuuya kangani kuzoongororwa kenza?

Kuziva mhinduro dzemibvunzo iyi kuchakubatsira kunzwisisa zviri nani chirwere ichi uye kunogona kukubatsira kujekesa marapirwo ako uye zvirongwa zvako zveramangwana.

Pakupedzisira, zvinhu zvekurangarira

Kunyange hazvo DFSP iri gomarara reganda risingawanzoitiki, kashoma kuti ripararire kune dzimwe nhengo dzemuviri. Zvisinei, kurapwa nekuvhiyiwa kwakakosha kuti umise kukura kwaro. Kuonekwa nekukurumidza uye kurapwa kwakakodzera kunogona kuvandudza maonero ako. Saka, ziva nezveganda rako uye ona chiremba kana ukaona chimwe chinhu chisingawanzoitiki. Hausi wega, uye kune vanachiremba vanogona kukubatsira parwendo urwu.

DFSP , kenza yeganda, kenza yeganda, mapundu eganda, kuvhiyiwa kweMohs, zviratidzo zvekenza, zvirwere zveganda