Pane dzimwe nguva paunonzwa kumanikidzwa kwakanyanya, kungave kuri nekuda kwekuti une bvunzo iri kuuya, kana kuti wakapihwa basa guru kuhofisi, kana kuti wakasangana nedambudziko kumba? Chipfuva chako chiri kurova, uri kudikitira, uye unonzwa kunetseka kusinganzwisisike. Panguva dzakadai, tinoti, "Ndiri kushushikana." Asi wakambozvibvunza here kuti chii chinoitika mukati memiviri yedu kana 'kushushikana' uku kwasvika? Kuseri kwezvose izvi kune system inoshamisa kwazvo, inongozvidzora mumuviri wedu. Nhasi tichataura nezvazvo.
Zvichitaurwa zviri nyore, chii chinonzi HPA axis?
HPA Axis inzvimbo yakakosha yekutaurirana mumuviri wedu. Kutaura chokwadi, ikubatana pakati penhengo nhatu huru mumuviri wedu. Ndiyo sisitimu huru inodzora kushushikana mumuviri wedu. Funga nezvayo sechikwata chekutarisira emergency mukati memuviri wedu. Kune vatungamiriri vatatu vechikwata ichi. Vanotumirana mameseji uye vanoshanda pamwe chete. Isu tinodana sisitimu iyi kuti HPA axis.
Mukurapa, HPA axis isystem ye neuroendocrine. Kureva kuti, isystem inoburitsa ma chemical messenger anonzi mahormone muropa nekuda kwezviratidzo zvinobva kusystem yedu yetsinga. Mahormone aya anoudza miviri yedu maitiro ekugadzirisa kushushikana.
Ndivanaani vatungamiriri vatatu veboka iri?
Sezvatakambotaura, kune nhengo huru nhatu dzehurongwa uhwu. Idzi nhatu ndidzo dzinotungamira hurongwa uhu hwese. Ngationei kuti vatatu ava ndivanaani uye mabasa avo ndeapi.
| Nhengo | Nzvimbo uye tsananguro | Zvaunoita zviri nyore. |
|---|---|---|
| Hypothalamus | Izvi zviri mukati-kati mepfungwa dzedu. Zvinobatsira kudzikamisa zvinhu zvakawanda mumuviri wedu, zvakaita sekupisa, nzara, uye manzwiro. | Iyi ndiyo imba huru yekudzora zvinhu . Uyu ndiye munhu wekutanga kuita sarudzo kana pakaitika emergency. |
| Gland rePituitary | Gland diki, rakaita semapfupa riri pasi pe hypothalamus. Kunyange zvazvo riri diki, rinodzora mamwe magland akawanda mumuviri. | Uyu ndiye Maneja . Ndiye anopa maodha kubva muimba huru yekutonga kuenda kune vamwe. |
| Adrenal glands | Matinji maviri madiki ane mativi matatu akafanana nengowani mbiri dziri pamusoro peitsvo dzedu. | Iyi ndiyo unit inoshanda . Ndipo panogadzirwa mahormone ekushushikana uye anoburitswa muropa, zvichienderana nemirairo yemaneja. |
Izvi zvitatu zvinoshanda sei pamwe chete?
Kurongeka kwezvitatu izvi kwakanyatsorongeka. Zvakafanana nekuita kwecheni. Ngatinzwisisei nemuenzaniso.
Fungidzira kuti uri kufamba mumugwagwa uye kamwe kamwe imbwa inosvetuka pauri. Unotya. Mumasekondi mashoma iwayo, zvinhu izvi zvinoitika mumuviri wako:
1. Danho rekutanga: Uropi hwako hunodudzira zvinoonekwa nemaziso ako sekuti "Iyi injodzi!" Pakarepo, meseji inotumirwa kuhypothalamus (nzvimbo huru yekudzora) kuburikidza nehurongwa hwetsinga hwe autonomic. Hypothalamus inoburitsa meseji yemakemikari inonzi `CRH` (Corticotrophin-releasing hormone).
2. Danho rechipiri: Meseji iyi ye'CRH' inoenda zvakananga kugland repituitary (maneja) . Painogamuchira meseji iyoyo, gland repituitary rinoburitsa rimwe hormone rinonzi 'ACTH' (Adrenocorticotropic hormone) muropa. Izvi zvakafanana nekuraira kuti "Enda!"
3. Danho rechitatu: Homoni inonzi `ACTH`, inofamba nemuropa, inosvika kuma adrenal glands (chikamu chinoshanda) . Painogamuchira murairo iwoyo, ma adrenal glands anogadzira huwandu hwakawanda hwehomoni yedu huru yekushungurudzika, cortisol, uye anoiburitsa muropa.
Cortisol haisi hormone yakaipa chete. Pakukurumidzira, hormone iyi inowedzera huwandu hweshuga mumuviri wedu, inokwidza BP yedu, uye inodzikisa kushanda kwemasoja emuviri kwenguva pfupi. Zvese izvi zvinoitirwa kuti tiwane simba ratinoda kuti tipfuure nekukurumidzira (kutiza imbwa). Izvi zvinonzi "Kurwa-kana-Kubhururuka".
Asi sisitimu iyi haifanirwe kugara ichishandiswa nguva dzese. Kana imbwa yaenda, ndiko kuti, kana njodzi yapera, sisitimu iyi inofanira kumira. Uye zvinoitika nenzira isinganzwisisike. Kana huwandu hwecortisol muropa hukawedzera, inotumira chiratidzo kuuropi (hypothalamus nepituitary gland) ichiti, "Zvakanaka, ikozvino dambudziko ragadziriswa, rega kutumira mameseji iwayo e'CRH' ne'ACTH'." Izvi ndizvo zvatinodaidza kuti negative feedback loop . Zvakafanana nekudzima switch kana basa rapera.
Zvinokwanisika here kuti sisitimu iyi haisi kushanda zvakanaka?
Ehe, zvinogona zvechokwadi. Pane nzira mbiri huru idzo hurongwa uhwu hwakarongeka hunogona kukanganiswa nadzo. Imwe ndeyekunyanya kushanda, uye imwe ndeyekushaikwa kwebasa.
Kusashanda zvakanaka kweHPA Axis
Fungidzira, uri kushushikana nguva dzese. Zvakafanana nembwa dzinosvetuka nguva dzese. Matambudziko kuhofisi, matambudziko kumba, matambudziko emari... Kana uine rudzi urwu rwekushushikana kwenguva refu, system iyoyo haina zororo. Inogara ichishanda. Ipapo huwandu hwe cortisol hunogara hwakakwira . Izvi zvinokuvadza zvikuru miviri yedu.
| Sisitimu yakakanganiswa | Matambudziko angangoitika |
|---|---|
| Sistimu yekudzivirira muviri | Kusasimba kwemasimba emuviri, kurwara-rwara, kuzvimba kwakanyanya mumuviri, uye njodzi yezvirwere zvemuviri zvinorwisa muviri . |
| Hutano hwepfungwa | Njodzi yekurwara nepfungwa dzakadai sekuora mwoyo, matambudziko ekuzvidya mwoyo, uye chirwere chekushushikana mushure mekutambudzika (PTSD) . |
| Kugadzira muviri | Kuwanda kwenjodzi yekubatwa nechirwere cheshuga, kufuta, uye mamwe marudzi ekenza. |
| Mwoyo netsinga dzeropa | Kukwira kweropa uye njodzi yekukuvara kwetsinga dzeropa. |
Pamusoro pezvo, vaongorori vanotenda kuti kusashanda zvakanaka kweHPA axis kwenguva refu kunogona kukonzera kutadza kuyeuka uye zvirwere zvinokanganisa mashandiro etsinga zvakaita sechirwere cheAlzheimer .
Kudzvinyirira HPA Axis
Izvi ndizvo zvimwe. Kureva kuti, sisitimu yacho haishande zvakanaka kunyangwe ichifanirwa kupindura kushushikana. Chikonzero chikuru cheizvi imhando dzemishonga inotorwa kubva kunze.
Dambudziko iri rinogona kuitika, kunyanya kana munhu achitora mishonga ye corticosteroids (semuenzaniso, Prednisolone), iyo inoshandiswa pakurapa zvirwere zvakaita seasthma, COPD, arthritis, cancer, uye mushure mekuisirwa nhengo, kwenguva yakareba.
Chinoitika ndeichi: patinozvipa mishonga iyi kunze, miviri yedu inofunga kuti, "Hatichadi kugadzira cortisol, tinogona kuiwana kubva kunze." Ipapo ma adrenal glands edu (mafekitori) anononoka zvishoma uye anoderedza kugadzirwa kwe cortisol.
Chinoita kuti izvi zvive nengozi ndechekuti kana kamwe kamwe, dambudziko guru (rakadai setsaona kana hutachiona hukuru) rikaitika, muviri hauzokwanisi kugadzira huwandu hwe cortisol hunodiwa kuti ugadzirise dambudziko iri. Iri idambudziko re emergency rinogona kutokonzera njodzi kuhupenyu. Tinoridaidza kuti adrenal crisis .
Ndosaka chiremba achiti musangoerekana marega kutora mishonga yesteroid. Munofanira kuita izvi muchitevedzera mirairo yachiremba wenyu, muchideredza mwero wemushonga zvishoma nezvishoma.
Saka tingadzivirira sei hurongwa uhwu hunokosha?
Tsvagiridzo pamusoro peHPA axis ichiri kuenderera mberi, asi nzira yakanakisisa yekugadzirisa kushushikana ndeyekukugadzirisa nemazvo . Hatigoni kubvisa kushushikana muhupenyu hwedu zvachose. Asi tinogona kukutonga kuitira kuti kusabve mumaoko edu. Heano zvimwe zvinhu zviri nyore zvaunogona kuita kuti ubatsire:
- Ita zvinhu zvinodzikamisa pfungwa: Dzidzira zvinhu zvakaita sekufungisisa, yoga, uye maekisesaizi ekufema zvakadzama zuva nezuva.
- Chengetedza muviri wako zvakanaka: Idya chikafu chinovaka muviri, rovedza muviri zuva nezuva, uye wana nguva yakakwana yekurara. Izvi zvitatu zvakakosha zvikuru.
- Funga zvakanaka: Funga nezvezvinhu zvakanaka muhupenyu. Bvuma kuti haugone kudzora zvese. Kunetseka nezvinhu zvausingakwanise kuchinja kunongowedzera kushushikana kwako.
- Jaira kutaura kuti "kwete": Usatore mabasa matsva kana waremerwa.
- Chengetedza hukama nevanhu:Zvinonyaradza zvikuru kutaura zviri mupfungwa dzako neshamwari kana nhengo yemhuri iri pedyo newe uye inokunzwisisa.
Kana uchiri kunetseka kugadzirisa kushushikana kwako mushure mekuita zvinhu izvi, usanyara nazvo kana kutambura uri wega. Taura nachiremba wemhuri yako nezvazvo. Iye achakwanisa kukupa gwara raunoda kuti ukunde dambudziko iri.
Mharidzo Yekuenda Nayo Kumba
- HPA axis inzira yechisikigo uye inokosha inopindura kushushikana mumuviri wedu.
- Kushushikana kwenguva refu (kwenguva refu) kunogona kukonzera kuti muviri uyu ushande zvakanyanya, zvichikonzera matambudziko akawanda ehutano akadai sechirwere cheshuga, BP, uye zvirwere zvepfungwa.
- Mimwe mishonga ye corticosteroid inogona kudzvinyirira HPA axis. Haufanire kutanga kana kurega kutora mishonga yakadaro usina kupiwa mazano nachiremba.
- Kugadzirisa kushushikana kwezuva nezuva ndiyo nzira yakanakisisa yekuchengetedza hutano hwakanaka.
- Kana uchinetseka nedambudziko rekushushikana, enda kuna chiremba wako nekukasika kuti akupe mazano.
💬 Comments (0)
Hapana zvakataurwa parizvino. Isa mhinduro yako pano kekutanga.
Wedzera zvaunofunga