Kana chiremba wako akakuudza iwe kana mumwe munhu waunoziva kuti ane hutachiona hwakaita seHIV, Hepatitis C, kana COVID-19, unganzwa kutya nezvemishonga yavanokupa. Mibvunzo yakaita sekuti, 'Mishonga iyi ndeipi?' uye 'Inokanganisa sei muviri?' inouya mupfungwa dzako. Mishonga inodzivirira mapuroteni iboka rine simba remishonga inogona kupihwa kwauri panguva dzakadaro. Kunyangwe zita racho ringave rakaoma zvishoma, basa rayo rinokosha zvikuru. Nhasi, tichataura nezveizvi nenzira iri nyore, nenzira yaunogona kunzwisisa.
Ndezvipi zvinhu izvi zvinodzivirira mapuroteni?
Zvichitaurwa zviri nyore, iyi imhando yemishonga inopihwa kurapa hutachiona hwehutachiona. Basa rayo guru nderekumisa hutachiona kuti husazviite hwega uye husapararire mumuviri wedu. Zvakafanana nekudzora kupararira kwehutachiona.
Mushonga uyu unonyanya kushandiswa semushonga wekudzivirira chirwere cheHIV/AIDS . Unoshandiswawo kurapa zvirwere zvakaita sehepatitis C neCOVID-19.
Dzimwe nguva mushonga uyu unopihwa wega. Asi kazhinji, pakurapa zvirwere zvakaita seHIV, unopihwa pamwe chete nemimwe mishonga yakawanda inorwisa mavhairasi, senge 'cocktail'. Tinodaidza izvi kuti Antiretroviral Therapy (ART) . Dzimwe nguva, Protease Inhibitor inoshandiswa sekuwedzera kushanda kwemumwe mushonga.
Ndezvipi zvirwere zvikuru zvinorapwa nemushonga uyu?
Rudzi rwemishonga inonzi Protease Inhibitors inongobvumidzwa kurapa hutachiona hushoma chete.
- HIV/AIDS: Mishonga iyi inoshandiswa sechikamu chikuru chekurapa kweART kudzora HIV. Inoshandiswawo kudzivirira hutachiona mushure mekusangana neHIV (PEP) kudzivirira hutachiona mushure mekusangana neHIV (semuenzaniso, bonde risina kuchengetedzeka).
- Hepatitis C: Izvi zvinoshandiswa pamwe chete nemimwe mishonga inorwisa mavhairasi kurapa hutachiona hwehepatitis C.
- COVID-19: Kana vabatwa neCOVID-19, vanachiremba dzimwe nguva vanonyora musanganiswa wemhando mbiri dzeProtease Inhibitors kudzivirira chirwere ichi kuti chisanyanya kuipa.
Mushonga uyu unoshanda sei mumuviri?
Kuti tinzwisise izvi, ngatitorei muenzaniso mudiki. Fungidzirai vhairasi munhu anoda kugadzira keke. Kuti agadzire keke iri (kureva vhairasi itsva), anofanira kucheka chidimbu chikuru cheprotein kuita zvidimbu zvidiki. Izvi zvidimbu zvidiki zveprotein ndizvo 'zvinhu' zvinoshandiswa kugadzira mavhairasi matsva.
Pano, 'Protease' ienzyme inoshanda se'chigero' chinocheka ribhoni hombe reprotein.
Mushonga watinopa, ndiwo...Zvinoitwa ne'protease inhibitor' kuvharira 'chigero' (protease enzyme) kushanda. Kana chigero chamira kushanda, hutachiona hahugone kucheka 'zvinhu' zvahunoda kuti hugadzire mavhairasi matsva. Ipapo hutachiona hahugone kuzvibereka mumuviri uye kuzvigadzira makopi. Ndicho chokwadi chiri nyore.
Kana hutachiona hwacho hukarega kupararira nenzira iyi, zvinova nyore kuti masoja emuviri wedu arwise mavhairasi asara uye adzore chirwere chacho.
Ndedzipi mhando dzeProtease Inhibitors dzinonyanya kushandiswa?
Nekuti hutachiona hwega hwega hune enzyme yahwo yeprotease yakasiyana, mhando dzakasiyana dzeprotease inhibitors dzinoshandiswa kurapa HIV, Hepatitis C, uye COVID-19.
Pane nzira iri nyore yekuziva mazita emishonga iyi.
- Mishonga yeHIV inowanzoguma ne '-navir' .
- Dziya dzinopihwa dzehepatitis C dzinotanga nechivakashure '-previr' .
Tafura iri pazasi inogona kutsanangura izvi zvakanyanya.
| Chirwere chiri kurapwa | Mienzaniso yemishonga |
|---|---|
| MaProtease Inhibitors eHIV | Atazanavir Darunavir Lopinavir Ritonavir Saquinavir |
| MaProtease Inhibitors eHepatitis C | Boceprevir Glecaprevir Grazoprevir Simeprevir |
| MaProtease Inhibitors eCOVID-19 | Musanganiswa wemishonga miviri, Nirmatrelvir neRitonavir (inozivikanwa sePaxlovid®) |
Ndingasarudza sei mushonga wakakodzera ini?
Izvi zvinosarudzwa nachiremba ari kukurapa. Anofunga nezvezvinhu zvakawanda paanenge achiita sarudzo iyi.
- Utachiona hwako hwehutachiona: ingava HIV, hepatitis C, kana COVID-19.
- Hutano hwako hwese: Ungave uine zvimwe zvirwere, zvakaita sechirwere cheshuga, BP, itsvo kana chirwere chechiropa.
- Mimwe mishonga yauri kutora parizvino: Izvi zvakakosha zvikuru nekuti mimwe mishonga inogona kushanda pamwe chete neProtease Inhibitors idzi.
- Wakambotora mimwe mishonga yechirwere ichi here?
- Mhando yehutachiona hwaunahwo: Mamwe marudzi ehutachiona haapindure kune mimwe mishonga.
- Migumisiro inogona kuitika: Sarudza mushonga unonyatsokodzera muviri wako uye une migumisiro mishoma.
Zvakakosha: Zvakakosha kuudza chiremba wako nezvemishonga yese yaunotora (kusanganisira mavhitamini nemishonga yemishonga) uye chero matambudziko ehutano auri nawo. Izvi zvinogona kubatsira kudzivirira migumisiro yakaipa uye kusangana kwemishonga.
Ndezvipi zvakanakira kushandisa mushonga uyu?
Mabhenefiti emishonga iyi akanyanya kunaka.
- Sechikamu chekurapa neART, HIV inogona kudzorwa kusvika padanho rekuti haionekwe mumuviri.
- Inobatsira kurapa zvachose hutachiona hwehepatitis C.
- Kana ukabatwa neCOVID-19, zvinobatsira kudzivirira chirwere ichi kuti chisanyanya kuipa .
Ndezvipi migumisiro nezvinetso zvinogona kuitika?
Kufanana nemushonga upi zvawo, maProtease Inhibitors anogona kukonzera migumisiro yakaipa. Zvisinei, havasi vese vanoawana. Zvakare, anosiyana zvichienderana nemushonga waunotora uye mamiriro ehutano hwako.
| Rudzi rwemhedzisiro yakaipa | Mienzaniso |
|---|---|
| Migumisiro yakajairika | |
| Matambudziko ekugaya chikafu | Kurwadziwa kwemudumbu, kuda kurutsa uye kurutsa, manyoka |
| Zvimwe zvinhu zvakajairika | Mapundu paganda, kukosora, kuneta, kuravira kusingafadzi mumuromo |
| Kuchinja kwemuviri | Matombo eitsvo, kuchinja kwenzvimbo yemafuta mumuviri (Lipodystrophy) |
| Migumisiro yakaipa asi isingawanzoitiki | |
| Mhedzisiro panhengo dzemukati | Kukuvara kwechiropa, kubuda ropa mukati (kusanganisira kubuda ropa mukati medehenya) |
| Matambudziko eganda akakomba | Stevens-Johnson syndrome - mapundu anorwadza, anoputika muviri wese |
| Kuchinja mu metabolism | Kuwedzera kweshuga muropa (Hyperglycemia), kuwedzera kwecholesterol muropa (Hyperlipidemia) |
| Zvimwe zvirwere zvakakomba | Kurwara kwemwoyo, Hemolytic Anemia, Matambudziko nekushanda kwemagetsi emwoyo |
Ndinofanira kutora mushonga uyu kwenguva yakareba sei?
Izvi zvinoenderana nechirwere chaunacho.
- HIV: Sezvo pasina mushonga wakakwana weHIV parizvino, kurapwa kunodiwa kwehupenyu hwako hwese. Nzira dzekurapa nemishonga zvinogona kuchinja nekufamba kwenguva.
- Hepatitis C: Chirwere ichi chinogona kurapwa nemavhiki mashoma kana mwedzi yekurapwa.
- COVID-19: Kurapa kweCOVID-19 nemishonga inorwisa hutachiona kunowanzoitwa kwemazuva mashanu.
Pane zvandingaita here kuti kurapwa kuve nyore?
Ehe, zvechokwadi. Pane zvinhu zvishoma zvaunogona kuita kuti uderedze migumisiro yakaipa uye kuti kurapwa kubudirire.
- Inwa mushonga wako sezvawaudzwa nachiremba, nenguva, uye usadarike kana dose imwe chete.
- Inwa mvura yakawanda.Izvi zvinobatsira kudzivirira zvinhu zvakaita sematombo eitsvo.
- Dzivisa kushandisa mimwe mishonga inogona kukanganisa mushonga wako. Bvunza chiremba wako nezvazvo.
- Mimwe mishonga inofanira kutorwa pamwe chete nechikafu. Tichaenderera mberi nekuongorora izvozvo.
Sei mamwe maProtease Inhibitors achiti anofanira kutorwa nechikafu?
Pane chikonzero cheizvi. Mimwe mishonga inodzivirira mapuroteni, kunyanya iya inotorwa nemafuta, inonyudzwa zviri nani muura hwedu. Izvi zvinowedzera kushanda kwemushonga. Saka iva nechokwadi chekubvunza chiremba wako kana uchifanira kutora mushonga wako usati wadya, wapedza, kana kuti usati wadya.
Unofanira kuona chiremba rini?
Kana ukasangana nemigumisiro mitsva isingatarisirwi, kana kuti uine mibvunzo nezvekurapa kwako, usazeza kutaura nachiremba wako.
Kana ukasangana nedambudziko guru rinotevera, tsvaga rubatsiro rwechiremba nekukasika. Enda kuchipatara cheEmergency Department (ETU) nekukurumidza.
- Kupindwa nechando
- Kuvhiringidzika kana kuchinja pfungwa
- Kutsvuka kwemaziso kana ganda (Jaundice)
- Maronda anorwadza, anoputika, uye akapararira
- Kurwadziwa kwakanyanya mudumbu
- Kurutsa kwakanyanya kusingagone kumiswa
Mishonga inodzivirira mapuroteni imhando yemishonga inokosha uye inoponesa hupenyu mukurapa zvirwere zvakaita seHIV neHepatitis C. Kana uine mibvunzo kana zvinokunetsa nezvekurapa uku, taura nachiremba wako nezvazvo pachena. Vanogona kukubatsira kugadzira hurongwa hwekurapa hunokushandira zvakanaka.
Mharidzo Yekuenda Nayo Kumba
- Mishonga inodzivirira mapuroteni iboka rine simba remishonga inodzora hutachiona hwakaita seHIV, Hepatitis C, uye COVID-19.
- Izvi zvinoshanda nekumisa hutachiona kuti husazviite hwega mumuviri uye kuti husapararire.
- Zvakakosha kuudza chiremba wako nezvemishonga yese yaunotora uye chirwere chega chega chaunacho kuti udzivise migumisiro yakaipa.
- Inwa mushonga wako sezvawaudzwa nachiremba wako, panguva chaiyo. Usapotsa kana wangotora mushonga mumwe chete.
- Kana ukasangana nematambudziko akakomba (fivha, kutsvuka kweganda, maronda akanyanya), usatambisa nguva uye tsvaga rubatsiro rwechiremba nekukasika.
💬 Comments (0)
Hapana zvakataurwa parizvino. Isa mhinduro yako pano kekutanga.
Wedzera zvaunofunga