Ngatidzidzei nezveRadiopharmaceuticals nenzira iri nyore. Izvi zvichave zvakakosha zvikuru kwamuri!

Pamwe unotya zvishoma paunonzwa izwi rekuti "radiopharmaceuticals," handiti? Izwi rekuti "radioactive" rinokuyeuchidza chimwe chinhu chine njodzi, asi kana chikashandiswa zvakanaka mukurapa, chinogona kubatsira zvikuru. Saka nhasi, ngatitaurei nezvezvazviri, mashandiro azvo, uye kuti zvakachengeteka sei kwauri.

Chii chinonzi mishonga iyi yemagetsi? Ngatizvinzwisise zviri nyore!

Zvichitaurwa zviri nyore, aya `(Radiopharmaceuticals)` imhando yakakosha yemushonga . Asi ane kachikamu kadiki keradioactive, ndiko kuti, ane radioactive. Musazvidya mwoyo, iyi radioactivity inodzorwa uye yakachengeteka. Vanachiremba vedu, kureva vanachiremba nevamwe vanopa hutano, vanoshandisa mishonga iyi pakuongorora mifananidzo mumishonga yenyukireya uye kurapa zvimwe zvirwere, kunyanya kenza .

Funga nezvazvo, kana vachida kuona kana paine chisina kumira zvakanaka mumuviri wako, dzimwe nguva vanachiremba vanokupa mushonga mudiki wekunwa kana jekiseni usati waongororwa? Izvi zvakafanana. Mishonga iyi yakakosha inogadzirwa uye inopihwa nevanhu vakadzidziswa zvakanyanya vanonzi nuclear pharmacist . Zvadaro , vanachiremba veX-ray neX -ray technologists (RTs) vanoishandisa kuita bvunzo dzekuongorora. Dzimwe nguva, vanachiremba veX-ray vanopawo mishonga iyi senzira yekurapa.

Mishonga iyi inoshandiswa pakurapa ne radiopharmaceuticals?

Mishonga iyi inonyanya kushandiswa muzvikamu zviviri. Ngationei kuti chii.

1. Mishonga yekuongorora Radiopharmaceuticals

Mishonga yekurapa inonzi radiopharmaceuticals inowanzo shandiswa mukuyedza mifananidzo yemishonga yenyukireya . Tinoidaidza kuti "kuongorora mishonga yekurapa inonzi radiopharmaceuticals." MuUnited States chete, zvinofungidzirwa kuti mamiriyoni emiedzo iyi yemishonga yenyukireya inoitwa gore rega rega. Saka unogona kufungidzira kuti inoshandiswa zvakadii.

Kuongororwa uku kunogona kutarisa kana nhengo dzemuviri wako dziri kushanda nemazvo . Izvi zvinoitwa seizvi:

Unopiwa mushonga uyu une radioactive shoma kuti unwe, ufeme, kana kubaya. Dzimwe nguva izvi zvinonzi radiotracers . Huwandu hwemushonga une radioactive hauzokukuvadzi. Huwandu hushoma kwazvo. Mushonga uyu unoenda kunzvimbo ine dambudziko mumuviri wako wozounganidza. Zvadaro, kamera ine hunyanzvi hwakanyanya, senge gamma camera, inoona mwaranzi mumuviri wako uye inogadzira mifananidzo inogona kuonekwa nachiremba .

Fungidzira, mushonga uyu wakafanana nemupurisa anopinda mumuviri, achitsvaga nzvimbo dzine dambudziko otiratidza kuti, "Apa ndipo pane dambudziko."

Heano mimwe mienzaniso yekushandiswa kwemishonga yekurapa inonzi radiopharmaceuticals pakuongorora chirwere ichi:

• Fluorine-18: Iyi iradiotracer inowanzoshandiswa muPET scans (Positron Emission Tomography scans).
• Technetium 99m: Ichi ndicho chinhu chinoshandiswa zvakanyanya mukurapa kwenyukireya. Chinoshandiswa kuongorora mapfupa, mashandiro echiropa, uye mashandiro eitsvo.
• Xenon-133: Uyu mushonga une radioactive waunofema. Unopihwa kuti utarise mashandiro emapapu (pulmonary function testing).
• Rubidium-82: Uyu mushonga unopihwa kwauri netsinga (IV). Unoshandiswa kutarisa mamiriro emhasuru yemwoyo (myocardial imaging).

2. Mishonga yekurapa yeRadiopharmaceuticals

Zvino ngatitaurei nezvekushandiswa kwemishonga iyi pakurapa. Iyi yakasiyana zvishoma neiyo inoshandiswa pakuongorora. Mishonga yekurapa inoburitsa mwaranzi ine simba uye inouraya masero . Izvi zvinoitirwa kuuraya masero asina hutano, kunyanya masero ekenza .

Mishonga iyi yakafanana ne "bounty hunters." Kureva kuti, vanowana masero ekenza voendesa radiation therapy zvakananga kumasero iwayo . Izvi zvakasiyana ne external beam radiation therapy , iyo inoshandisa muchina kutumira mwenje yemwaranzi kubva kunze kwemuviri wako. Asi mishonga iyi yekurapa inoshanda zvakananga nekunanga chinangwa.

Basa iri, kushandiswa kwemishonga ine mwaranzi pakurapa, inyaya itsva. Vaongorori vachiri kutsvaga mashandisirwo matsva avanoda. Vanotenda kuti mishonga ine mwaranzi ichaita basa rakakosha mukurapa kenza mune ramangwana.

Ndeipi mishonga yekurapa cancer inoshandiswa ne radiopharmaceuticals?

Kune mhando dzakasiyana dze "Radiopharmaceuticals" dzinoshandiswa navanachiremba kurapa kenza. Semuenzaniso:

• PLUVICTO® (lutetium Lu 177 vipivotide tetraxetan): Uyu mushonga unotenderwa neUS Food and Drug Administration (FDA). Unoshandiswa kurapa kenza yeprostate (PSMA-positive metastatic castration-resistant prostate cancer - PSMA-positive mCRPC).
• Lutathera™ `(Lutathera™ - Lutetium Lu 177 dotatate)`:Uyu mushonga unotenderwa neFDA. Unoshandiswa kurapa mamwe mabundu e neuroendocrine (somatostatin receptor-positive gastroenteropancreatic neuroendocrine tumors) anoitika mudumbu, muura, uye pancreas.
• Iodine-131: Iyi ndiyo nzira huru yekurapa ne radioactive iodine. Inogona kurapa mamwe magomarara ethyroid nemamwe maGraves' disease, anozivikanwawo se hyperthyroidism.
• Radium-223: Izvi zvinoshanda zvikuru pakurapa bundu remapfupa rinoitika kana kenza yeprostate yapararira (metastasizes) kuenda kumapfupa. US FDA yakabvumidza Radium-223 dichloride (Xofigo™) kuti ishandiswe pakurapa uku.

Pamusoro pezvo, mamwe marudzi akati wandei ekurapa ne radiopharmaceutical ari kuyedzwa pari zvino kune mamwe marudzi ekenza.

Ndeapi maradiopharmaceuticals anonyanya kushandiswa?

Sezvatakambotaura, Technetium-99m mushonga wekurapa unoshandiswa neradiopharmaceutical unowanzo shandiswa navanachiremba. Unoshandiswa zvakanyanya pakuongororwa kwemifananidzo. Unobatsira "kuona" zvinotevera:

• Kuyerera kweropa mumapapu (pulmonary perfusion) mumapapu ako.
• Kuyerera kweropa mutsinga dzeropa (Vascular perfusion).
• Mapfupa.
• Mitezo yemwoyo.
• Matumbu emudumbu.
• Gland re thyroid.

Mamwe ma radiopharmaceuticals anoshandiswa zvakanyanya ndeaya:

• ¹⁸F Fluorodeoxyglucose `(¹⁸F Fluorodeoxyglucose - FDG)`
• Gallium-68 DOTATATE
• Gallium-68 PSMA `(Gallium-68 PSMA)`
• ¹⁸F PSMA `(¹⁸F PSMA)`
• Iodine 123 `(Iodine 123)`

Saka mishonga iyi yekurapa yakachengeteka zvechokwadi here?

Uyu mubvunzo unobvunzwa nevanhu vazhinji. Kana ukashandiswa uye uchitarisirwa nemazvo, mishonga yekurapa nemagetsi haina njodzi. Nyanzvi yako yekurapa nemagetsi kana radiation oncologist ichashanda nenyanzvi yemishonga yenyukireya kuti ive nechokwadi chekuti huwandu hwemishonga yekurapa nemagetsi hwakakodzera uye hwakachengeteka . Saka hapana chekunetseka nezvahwo.

Kufanana nemishonga yese, kurapwa nemwaranzi kunogona kukonzera mimwe migumisiro yakaipa . Zvisinei, mabhenefiti emushonga anowanzo kuve makuru pane njodzi. Chiremba wako achakutsanangurira migumisiro iyi inogona kuitika usati watanga kurapwa.

Kunyangwe mishonga yekurapa nemagetsi yave ichishandiswa kwemakumi emakore mukufungidzira nezvemishonga yenyukireya, yatotanga kushandiswa kurapa kenza munguva pfupi yapfuura. Vatsvaguri vachiri kudzidza kuti mishonga iyi yemagetsi inorwisa uye inouraya sei masero ekenza. Kana uchida kudzidza nezvemiedzo yekiriniki yemishonga yekurapa kenza, taura nachiremba wako. Vanofara kukubatsira.

Chekupedzisira, zvinhu zvinonyanya kukosha zvaunofanira kurangarira

Zvakanaka, saka, kubva pane zvatataura nezvazvo, izvi ndizvo zvinhu zvikuru zvaunofanira kurangarira:

• Mishonga yeRadiopharmaceuticals imhando yemushonga ine radioactivity inodzorwa .
• Izvi zvinonyanya kushandiswa pakuongorora mifananidzo (semuenzaniso PET scans, bone scans) uye kurapa zvimwe zvirwere, kunyanya kenza .
• Mukuongorora chirwere, izvi zvinoshanda se "Radiotracers", "zvichiratidza" nzvimbo dzemuviri dzine matambudziko.
• Mukurapa, izvi zvinobatsira kurwisa nekuparadza masero ekenza .
• Mishonga iyi yakachengeteka kana ikatorwa pasi pekutarisirwa kwakakodzera nachiremba . Sezvinoita mishonga yese, panogona kuva nemigumisiro midiki, asi mabhenefiti acho anowanzo kuipfuura.
• Basa iri, kunyanya mukurapa kenza, richiri kuchinja , uye zvimwe zvakawanda zvinogona kutarisirwa mune ramangwana.

Saka, nguva inotevera paunonzwa nezve "(Radiopharmaceutical)", wava kunzwisisa zviri nani kuti chii uye kuti chinoshandiswa chii, handiti? Kana uine mimwe mibvunzo, usazeza kubvunza chiremba wako.

Mishonga yeRadiopharmaceuticals , Mushonga weNyukireya, Kurapa Kenza, Kuskena, Kurapa neRadiation, Kuongorora