Mishonga yaunotora inogona kuisa hupenyu panjodzi here? Ngatikurukurei nezveSerotonin Syndrome

Uri munhu anotora mishonga yekuderedza kushungurudzika, migraine, kana kurwadziwa kwakanyanya here? Kana kuti unotora mishonga kubva kuvanachiremba vakati wandei nekuda kwechirwere chimwe chete here? Saka nyaya iyi ichave yakakosha kwauri. Nhasi tiri kutaura nezvechirwere chinogona kuitika mumuviri wedu nekuda kwemamwe marudzi emishonga, ayo anogona kutyisidzira hupenyu kana asina kunzwisiswa zvakanaka. Tinodaidza izvi kuti 'Serotonin Syndrome' . Usazvidya moyo, kana tikaziva nezvazvo zvakanaka, tinogona kudzivirira njodzi huru.

Zvichitaurwa zviri nyore, chii chinonzi Serotonin Syndrome?

Kuti tinzwisise izvi, tinofanira kutanga taziva kuti 'Serotonin' chii. Funga nezvayo semutumwa mudiki anotakura mashoko pakati pehuropi hwedu nemuviri wese. Mukurapa, tinoti vatumwa vemakemikari ava 'neurotransmitters'. Serotonin ineurotransmitter inokoshawo mumuviri wedu, ichidzora zvinhu zvakawanda zvakaita semanzwiro edu, kurara, uye kuda kudya.

Kazhinji, kana ukatora mushonga wakanyorerwa nachiremba, huwandu hweserotonin mumuviri hunenge hwakaringana. Zvisinei, kana nekuda kwechimwe chikonzero kemikari iyi inonzi serotonin ikawedzera zvakanyanya mumuviri wedu , kureva kuti, kana ikaungana muhuwandu husingakwanise kubatwa nemuviri, maitiro emuviri wedu pairi anonzi 'serotonin syndrome'. Izvi zvinogona kuva maitiro ane njodzi anokonzerwa nemhando yemushonga (maitiro emishonga).

Ndiani ane mukana mukuru wekuwana chirwere ichi?

Kutaura zvazviri, chero ani zvake wezera ripi zvaro anoshandisa mishonga, mishonga yekuwedzera, kana mishonga isingabvumirwe inokanganisa huwandu hweserotonin ari panjodzi. Dambudziko iri rinowanzoonekwa mumamiriro ezvinhu akadai seaya:

• Paunotanga mushonga mutsva: Paunongotanga mushonga mutsva unowedzera huwandu hwe serotonin mumuviri.
• Pakuwedzera mushonga: Kana chiremba wako akawedzera mushonga wauri kutotora.
• Pakushandisa mishonga yakawanda pamwe chete: Ichi ndicho chikonzero chine njodzi uye chinowanzoitika. Fungidzira, une kurwadziwa kwemajoini. Unotora mushonga wekurwadziwa kubva kune mumwe chiremba. Panguva ino, nekuti une hanya zvishoma, unoona mumwe chiremba wotorawo mushonga weizvozvo. Asi hauudzi chiremba wekutanga nezvemushonga wechipiri, kana chiremba wechipiri nezvemushonga wekutanga. Apa ndipo panowanikwa mukana mukuru wekushandisa mishonga miviri yekuwedzera serotonin pamwe chete usingazive uye zvichikonzera mamiriro aya.
• Kana ukatora mushonga wakawandisa: Kana ukatora mushonga wakawanda kupfuura wakatarwa, nemaune kana netsaona.

Zviratidzo zvacho ndezvipi? Tinozviziva sei?

Zviratidzo zve serotonin syndrome zvinogona kusiyana kubva pamunhu kusvika pamunhu. Vamwe vanhu vanogona kuona zviratidzo zvisina kunyanya kuipa, nepo vamwe vanogona kuona zviratidzo zvakakomba, zvinouraya. Zviratidzo izvi zvinowanzotanga mukati memaawa mashoma mushure mekutora mushonga mutsva kana kuchinja dose.

Kuti zvive nyore kunzwisisa, ngatikamurai zviratidzo izvi muzvikamu zvitatu.

Ndeipi mishonga iyi inowedzera huwandu hwe serotonin mumuviri?

Rondedzero iyi yakareba zvishoma, asi zvakakosha kuti ugare wakachengeteka kuti uzive izvi.

Mishonga yekuderedza kushushikana

Iyi ndiyo mishonga inowanzobatanidzwa ne serotonin syndrome. Njodzi yacho yakanyanya kukura kana ikatorwa pamwe chete nemimwe mishonga (semuenzaniso, mishonga yemigraine).

• SSRIs (Selective serotonin reuptake inhibitors): Mishonga yakaita seFluoxetine, Sertraline, Citalopram, Escitalopram, Paroxetine.
• SNRIs (Serotonin-norepinephrine reuptake inhibitors): Mishonga yakaita seVenlafaxine, Duloxetine, Desvenlafaxine.
• Mishonga yeTricyclic antidepressants: Mishonga yakaita seAmitriptyline, Nortriptyline, Imipramine.
• MAOIs (Monoamine oxidase inhibitors): Kunyangwe izvi zvisingachashandiswi zvakanyanya, zvinopihwa mune dzimwe nguva.

Mimwe mishonga

• Mishonga yekurwadziwa kwakanyanya: Mishonga inouraya marwadzo yakaita seTramadol, Pethidine (Meperidine), Fentanyl, uye Methadone.
• Mushonga wekukosora: Mamwe manyuchi ekukosora anowanikwa muzvitoro zvemishonga ane chinhu chinonzi Dextromethorphan . Izvi zvinogonawo kukanganisa huwandu hweserotonin mumuviri.
• Mishonga yemigraine: Mishonga yeTriptan yakaita seSumatriptan neRizatriptan.
• Mishonga yekurutsa: Mishonga yakaita seMetoclopramide neOndansetron.
• Mamwe maantibiotic: Mishonga inorwisa mabhakitiriya ine linezolid.
• Mushonga wekudzora mafungiro: Lithium.

Zvimwe zvinhu

• Mishonga yekuwedzera: Zvinhu zvakaita seSt. John's wort neGinseng.
• Mishonga isiri pamutemo: Zvinhu zvakaita seEcstasy (MDMA), LSD, Cocaine, Amphetamines.

Usavhunduke nerunyorwa urwu. Havasi vese vanozowana chirwere ichi mushure mekutora mumwe wemishonga iyi. Njodzi inongovapo chete kana ukashandisa mimwe yemishonga iyi pamwe chete, ukawedzera mushonga, kana kana muviri wako uchiinzwa.

Chiremba anoziva sei izvi?

Hapana kuongororwa kweropa kana scan chaiyo yekusimbisa serotonin syndrome. Chiremba achaongorora chirwere ichi zvichibva pazvinhu zvakati wandei:

1. Zviratidzo zvako: Teerera zvakanaka zvaunonzwa.

2. Kuongororwa kwemuviri: Kurova kwemoyo wako, BP, tembiricha yemuviri, uye mamiriro emhasuru zvichaongororwa.

3. Rondedzero yemishonga yauri kutora: Ichi ndicho chinhu chinonyanya kukosha.

Pamusoro pezvo, unogona zvakare kuongororwa ropa neweti, kuongororwa pachipfuva, kana kuongororwa neCT scan kuti uve nechokwadi chekuti hauna zvimwe zvirwere (semuenzaniso, hutachiona) zvinokonzera zviratidzo zvakafanana.

Ndezvipi zvinorapwa izvi?

Kurapwa kunoenderana nekuoma kwezviratidzo zvako.

• Kana uine zviratidzo zvisina kusimba: Marapirwo akajairika ndeekurega kutora mushonga wakakonzera zviratidzo. Izvi zvinowanzo pedza zviratidzo zvachose mukati memaawa makumi maviri nemana kusvika makumi manomwe nemaviri.
• Kana uine zviratidzo zviri pakati nepakati: Uchachengetwa muchipatara uye uchaongororwa kwemaawa angangoita makumi maviri nemana. Munguva iyi, uchapihwa saline (IV fluids) nemishonga yakaita se benzodiazepines yekuzvidya mwoyo.
• Kana uine zviratidzo zvakakomba: Iyi inyaya yekurapa. Uchapinda muchikamu chevarwere vane chirwere chakanyanya (ICU) uye uchapihwa rubatsiro rwekubatsira kufema, kudzora fivha yakanyanya, uye mishonga yekudzora kurova kwemoyo neBP. Dzimwe nguva, mushonga unonzi Cyproheptadine, unodzivisa kushanda kweserotonin, unogona zvakare kupihwa.

Tingazvidzivirira sei kubva mumamiriro ezvinhu aya?

Pane zvinhu zvishoma zviri nyore, asi zvakakosha zvikuru zvatinogona kuita kuti tidzivirirwe kubva mumamiriro ezvinhu ane njodzi aya.

1. Zvidzidzise nezvemishonga yako: Chengeta pasi zita, chiyero, uye chinangwa chemishonga yese yaunotora.

2. Udza chiremba wega wega zvizere: Kana uri kurapwa navanachiremba vakawanda, iva nechokwadi chekuudza chiremba mumwe chete nezvemishonga yawakanyorerwa nevamwe.

3. Usarega kutora mushonga usina kubvunza chiremba wako: Kunyangwe uchinzwa kusagadzikana, usarega kutora mushonga kana kuchinja mwero wemushonga usina kutaura nachiremba.

4. Chenjerera paunenge uchitenga mushonga kubva ku pharmacy: Paunotenga mushonga wezvinhu zvakaita sekukosora nedzihwa, kumbira mushonga unoenderana nemushonga wauri kutotora.

5. Nyatsoteerera zviratidzo: Nyatsoteerera chero shanduko dziri kuitika mumuviri wako, kunyanya kana uchitanga mushonga mutsva kana kuwedzera mushonga wacho.