Dambudziko rinouya nekurapwa kwegomarara: Ngatidzidzei nezve Tumor Lysis Syndrome!

Kurarama negomarara idambudziko guru. Kunyangwe kurapwa kwakadai se chemotherapy kuchigona kubatsira kuparadza masero egomarara, dzimwe nguva kurapwa ikoko kunogona kukonzera matambudziko asingatarisirwi. Nhasi, tichataura nezve emergency inoda kutarisirwa nekukurumidza uye inogona kutoisa hupenyu panjodzi . Izvi zvinonzi Tumor Lysis Syndrome.

Chii chinonzi Tumor Lysis Syndrome? Ngatinzwisise zviri nyore.

Zvichitaurwa zviri nyore, Tumor Lysis Syndrome iboka rezvirwere zvakakomba zvinoitika kana masero akawanda ekenza akafa panguva imwe chete uye zviri mukati memasero iwayo zvikaburitswa muropa. Fungidzira, chirwere ichi chinogona kuitika mukati memaawa mashoma ekutanga kurapwa kwekenza. Chinogona kukura nekukurumidza uye kuva chirwere chinoda kurapwa nekukurumidza. Nokudaro, vanachiremba vanogara vachitarisa izvi.

Asi pane mashoko akanaka. Vanachiremba vane nzira dzekudzivirira Tumor Lysis Syndrome kuti isaitike . Vanoita izvi nekuona kuti ndiani ari panjodzi huru uye kutora matanho ekuderedza njodzi iyoyo.

Chii chinoitika kumiviri yedu mumamiriro ezvinhu aya?

Kana masero egomarara akasangana nekushushikana, kunyanya kubva mukurapwa kwakadai se chemotherapy, anoputsika. Zvadaro, makemikari nehupfu huri mukati memasero iwayo zvinongoerekana zvaungana muropa rakawanda. Dambudziko rinotanga kana muviri wedu usingakwanise kubvisa izvi nekukurumidza. Iyi tumor lysis syndrome inogona kukanganisa mwoyo yedu, itsvo, uye tsandanyama. Ngationei kuti migumisiro iyi ndeipi:

• Hyperuricemia - Izvi zvinoreva kuwedzera kwehuwandu hwe uric acid: Kana uric acid muropa ikawedzera, inogona kuchengetwa muitsvo, zvichikonzera kusashanda zvakanaka kweitsvo uye kutotadza kushanda zvakanaka kweitsvo. Funga nezvazvo sekuvharika kwepombi yemvura.
• Hyperphosphatemia - kureva kuti, phosphorus yakawedzera: Kuwedzera kwephosphorus muropa kunokanganisawo mashandiro eitsvo.
• Hyperkalemia - Izvi zvinoreva potassium yakakwira: Kana potassium yakakwira, unogona kuona zviratidzo zvakaita sekusvotwa, kurutsa, uye manyoka. Kwete izvozvo chete, asi kurova kwemoyo wako kunogona kuchinja, zvichikonzera kusagadzikana kwemoyo, uye pamwe kutoita chirwere chemwoyo. Izvi zvine njodzi zvishoma, handiti?
• Uremia: Izvi zvinoitika kana itsvo dzikarega kusvina chepfu kubva muropa. Uremia inogona kukonzera matambudziko akakomba pamapfupa, tsandanyama, mwoyo, uye tsinga dzeropa.
• Hypocalcemia - Kuderera kwecalcium muropa: Kuderera kwecalcium muropa kunogona kukonzera shanduko mumoyo, kurwadziwa kwetsandanyama, kuvhiringidzika, kusanzwa uye kukwenya mumakumbo. Dzimwe nguva, kunyange kufa nekuda kwekumira kwemoyo kunogona kuitika.

Chinhu chinonyanya kukosha: Tumor Lysis Syndrome inoitika kana chimwe chezvirwere izvi chikasangana.

Tumor Lysis Syndrome idambudziko here?

Ehe, zvechokwadi! Tumor Lysis Syndrome chirwere chinoda kurapwa nekukasika. Saka, zvakakosha kuziva izvi.

Ndiani anogona kubatwa nechirwere ichi?

Havasi vese vanorapwa kenza vanowana Tumor Lysis Syndrome. Kana uri kurapwa kenza, zvakanaka kubvunza chiremba wako nezvazvo. Kazhinji, vanhu vanorapwa chemotherapy yemhando dzinotevera dzekenza vari panjodzi huru yekuva nechirwere ichi:

• Chirwere cheLeukemia Chinouraya Chepamuviri (Acute Lymphocytic Leukemia)
• Lymphoma yeNon-Hodgkin's ine hukasha, yakadai seBurkitt Lymphoma uye Diffuse Large B-cell Lymphoma
• Chirwere cheAcute Myeloid Leukemia (AML)
• B-cell Acute Lymphoblastic Leukemia (ZVOSE)
• Kenza yeMapapu Masero Madiki

Uyewo, kune dzimwe mhando dzegomarara, idzo, kana dzikarapwa, dzine mukana mudiki wekuva nechirwere ichi. Asi hadzina kupera zvachose. Mienzaniso:

• Anaplastic Large Cell Lymphoma - Iyi igomarara risingawanzoitiki, rinokura zvishoma nezvishoma remasoja emuviri.
• Chirwere cheLeukemia Chisingaperi cheLymphocytic (CLL)
• Neuroblastoma
• Kenza yemazamu
• Sarcoma yenyama yakapfava
• Medulloblastoma
• Kansa yeMerkel Cell

Ndezvipi zvimwe zvinokonzera Tumor Lysis Syndrome?

Vanachiremba vanoziva kuti vamwe vanhu vari panjodzi huru yekuva nechirwere ichi. Kungwarira kwakakosha kunotorwa vasati vapa vanhu vakadaro chemotherapy. Heano mamwe manyuko anowedzera njodzi:

• Kuva nemasero machena akawanda eropa.
• Uric acid yakawanda muropa yatove yakakwira.
• Kuva nematambudziko eitsvo.
• Kuderera kwehuwandu hwemvura mumuviri (Kushaya mvura mumuviri).
• Kuva nekenza padanho rakakomba (Later-stage Cancer).
• Kuva nemabundu makuru.

Dambudziko iri rinogona kuitika here pasina chemotherapy?

Ehe, asi hazviwanzoitiki . Kana zvikaitika, vanachiremba vanoti chirwere cheSpontaneous Tumor Lysis Syndrome.

Ndezvipi zviratidzo zveTumor Lysis Syndrome?

Zviratidzo izvi zvinowanzoonekwa mukati memaawa gumi nemaviri kusvika makumi manomwe nemaviri mushure mekutanga kurapwa nechemotherapy. Hezvino izvo zviri:

• Kusvotwa nekurutsa.
• Manyoka.
• Kuchinja kwehuwandu hweweti yaunobuda nayo (kunogona kuwedzera kana kuderera).
• Kushaya simba uye Kuneta.
• Ropa muweti (Hematuria).
• Zvirwere zvepfari, kureva pfari.
• Kurwadziwa kwetsandanyama.
• Kusawirirana.
• Kurova kwemoyo kusina kurongeka.
• Kuderera kweropa (Hypotension).
• Kurwadziwa kwemajoini.

Kana ukaona chimwe chezviratidzo izvi kana kupfuura paunenge uchirapwa kenza, unofanira kuzivisa chiremba nekukasika.

Sei chirwere cheTumor Lysis chichiitika?

Zvichitaurwa zviri nyore, chirwere ichi chinoitika kana kurapwa kwegomarara kuchikonzera kuti masero akawanda egomarara afe kamwe kamwe uye nekukurumidza. Zvinhu zviri mukati memasero ari kufa (zvakadai sepotassium, phosphorus, uye uric acid) zvinongoerekana zvaungana muropa.

Kazhinji, itsvo dzedu ndidzo dzinobvisa zvinhu zvisingadiwi. Asi, kana masero akawanda akafa panguva imwe chete, itsvo hadzigone kuita basa iri. Zvakafanana nedhiraini rinovharika kana marara akawanda akapinda panguva imwe chete. Ipapo chepfu idzi dzinotanga kuungana mumuviri.

Vanachiremba vanoongorora sei chirwere ichi?

Chinangwa chikuru chevanachiremba ndechekudzivirira Tumor Lysis Syndrome. Kuti vaite izvi, vanozogara vachiita bvunzo dzeropa neweti kuti vave nechokwadi chekuti itsvo dzako dziri kushanda zvakanaka uye kuti chepfu dziri kubviswa mumuviri wako.

Ndeipi mishonga yekurapa Tumor Lysis Syndrome?

Kuedza kwekutanga kwavanachiremba kudzivirira izvi. Vanozviita nekuona avo vari panjodzi huru uye kutora matanho akakosha ekudzivirira. Asi, kana chirwere chikaitika, kurapwa kunotanga ipapo ipapo.

Zvinhu zvekuita kudzivirira:

• Kunyudza mvura mumuviri (mutsinga): Izvi zvinobatsira kuchengetedza huwandu hwemvura mumuviri hwakanaka, kukurudzira weti, uye kubatsira kubvisa chepfu mumuviri nekukurumidza.
• Kupa mishonga inodzivirira kuiswa kwemakristaro euric acid muitsvo: Kune mimwe mishonga inobatsira kudzora huwandu hweuric acid mumuviri.

Kurapwa kana chirwere ichi chikaitika:

• Kupa mishonga inobvisa tsvina mumuviri: Izvi zvinobatsira kubvisa chepfu mumuviri nekukurumidza.
• GLISH: Kupa mishonga inobvisa potassium nephosphorus yakawandisa.
• Kupa mishonga inonyungudutsa makristaro euric acid akaumbwa muitsvo.
• Dialysis: Kana itsvo dzako dzisiri kushanda zvakanaka, ungangoda dialysis kubvisa chepfu muropa rako. Izvi zvakafanana nekuita basa reitsvo dzako nekugadzira.

Ko Tumor Lysis Syndrome inogona kurapwa here?

Ehe, zvechokwadi! Vanhu vanosvika 90 muzana vanowana chirwere ichi vanopora. Chinhu chakakosha ndechekuchiongorora nekukurumidza uye kutanga kurapwa nekukurumidza.

Chii chinoitika mushure mekunge chirwere ichi charapwa?

Tumor Lysis Syndrome inogona kukonzera kukuvara kweitsvo dzako. Saka, kana uine chirwere ichi, zvakakosha kubvunza chiremba wako kana uchida kurapwa kwakawedzerwa kana kutarisirwa kwakakosha kusvika itsvo dzako dzapora.

Kurapa kenza kuri kuvandudzika zuva nezuva, zvichitibvumira kuparadza masero ekenza nekukurumidza. Zvisinei, dzimwe nguva, kana masero aya afa, makemikari nehupfu hwaanoburitsa zvinogona kukonzera chirwere chine njodzi chinonzi Tumor Lysis Syndrome. Izvi zvinogona kukanganisa zvikuru moyo neitsvo.

Pakupedzisira, zvekurangarira (Mharidzo Yekuenda Kumba)

Kurapwa kwegomarara idambudziko. Munguva iyi, zvakakosha kuziva nezvenjodzi dzakadai seTumor Lysis Syndrome. Kana uri kurapwa gomarara, iva nechokwadi chekubvunza chiremba wako kana uri panjodzi yechirwere ichi. Vachakutsanangurira njodzi dzacho uye vachaedza zvese zvavanogona kudzivirira kana kurapa chirwere ichi kana chikaitika. Usaregeredza chero zviratidzo, uye taurira chiremba nekukurumidza kana ukaona chimwe chinhu chisingawanzoitiki. Kutarisira hutano hwako ndicho chinhu chakakosha!

Tumor lysis syndrome, kurapwa kwekenza, chemotherapy, chirwere cheitsvo, hyperkalemia, hyperuricemia, emergency yekurapa