Chirwere cheSickle Cell chirwere chinogona kuva dambudziko guru muhupenyu. Avo chete vakambosangana nacho ndivo vanoziva kuti zvakaoma sei kurarama nekurwadziwa nguva dzose, kuneta, nezvimwe zvinetso. Zvisinei, nekufambira mberi kwesainzi yezvekurapa, mishonga mitsva yakawanikwa ichidzora zvirwere zvakadaro. Imwe yemishonga mitsva uye inobudirira ndeyeVoxelotor. Saka kana chiremba wako akakunyorera mushonga uyu, zvakakosha kuti uzive zvizere nezvawo. Nhasi, ngatitaurei nezvemapiritsi aya eVoxelotor.
Mushonga werudzii unonzi Voxeletor?
Zvichitaurwa zviri nyore, Voxeletor imhando yemushonga unoshandiswa kurapa chirwere chesickle cell . Panyaya dzezvekurapa, iri muboka remishonga inonzi `hemoglobin S polymerization inhibitors`.
Zvino ungave uchishamisika kuti chii ichocho. Zviri nyore kwazvo. Munhu ane chirwere chesickle cell ane protein inonzi hemoglobin mumasero matsvuku eropa ayo akasiyana zvishoma. Kana mwero weokisijeni wakaderera, mamorekuru aya ehemoglobin anonamatirana, achigadzira cheni refu dzinochinja chimiro chemasero matsvuku eropa. Masero matsvuku eropa akatenderera akajairwa anokombama kuita chimiro chesickle. Masero aya esickle ndiwo anonamira mutsinga diki dzeropa, zvichikonzera matambudziko akadai sekurwadziwa uye kukuvara kwenhengo.
Saka, zvinoitwa neVoxeletor ndezvekuti inodzivirira mamorekuru ehemoglobin kuti asaungane pamwe chete (polymerization). Izvi zvinoderedza masero matsvuku eropa akaita sejeko uye zvinoabatsira kuchengetedza chimiro chawo chakakodzera. Izvi zvinoita kuti ropa rifambe zvakanaka uye zvinoderedza matambudziko echirwere zvakanyanya.
Zvinhu zvekuudza chiremba wako usati watanga mushonga uyu
Usati watanga kurapwa neVoxelotor, zvakakosha kupa chiremba wako tsananguro yakazara yehutano hwako. Iva nechokwadi chekutaura zvinhu izvi kunyanya.
- Kana uine chirwere chechiropa: Kana chiropa chako chisina kushanda zvakanaka, zvinogona kukanganisa kubviswa kwemushonga mumuviri wako. Saka, chiremba wako angangoda kuchinja mwero wemushonga.
- Kana wakambova neallergy neVoxelotor kana chero mumwe mushonga kana chikafu: Vamwe vanhu vane allergy kune mimwe mishonga. Saka iva nechokwadi chekutiudza kana wakambosangana nedambudziko iri.
- Kana uine pamuviri kana kuti uchironga kubata pamuviri: Unofanira kungwarira zvikuru pakushandisa mishonga panguva yekuzvitakura. Saka iva nechokwadi chekutaura nachiremba wako nezvazvo.
- Kana uri amai vanoyamwisa: Mimwe mishonga inogona kupfuudzwa kumwana wako kuburikidza nemukaka wemuzamu. Saka, zivisa chiremba wako nezveizvi zvakare.
Ndinofanira kushandisa mapiritsi aya sei?
Kuti mushonga uwane pundutso yakakwana, zvakakosha kuushandisa nemazvo.
- Medza piritsi iri rose negirazi remvura. Usambopwanya, kupwanya, kana kutsenga piritsi. Medza piritsi rose. Kusaita izvi kunogona kuchinja mapindiro anoita mushonga mumuviri, zvichideredza kushanda kwawo.
- Unogona kutora mushonga uyu uchidya kana usina. Zvisinei, kana uchinzwa kurwadziwa mudumbu kana kuda kurutsa, zvakanaka kuutora mushure mekudya.
- Inwa mushonga wako zuva nezuva, sezvawakarairwa nachiremba wako. Usautore rimwe zuva wozorega rimwe zuva.
- Kunyangwe uchinzwa zviri nani, usarega kutora mushonga usina kurairwa nachiremba wako.
Zvakakosha: Mushonga uyu wakanyorerwa iwe chete. Usape mushonga uyu kune mumwe munhu ane zviratidzo zvakafanana nezvako. Zvingave zvine njodzi.
Kana ukapa mushonga uyu kuvana...
Vanachiremba vanopawo mushonga uyu kuvana vane makore anopfuura gumi nemaviri mune dzimwe nguva. Zvisinei, chiremba wevana ndiye anofanira kusarudza. Saka, kana uri kupa mwana wako mushonga uyu, taura nachiremba wako nokungwarira uye uwane mazano.
Chii chaunofanira kuita kana ukarasikirwa nedosi remushonga?
Kana ukakanganwa kutora mushonga, usazvidya moyo. Dzokera mushonga wausina kutora wotora mushonga unotevera panguva yawakajaira. Usambofa wakatora mushonga wakapetwa kaviri kuti udzorere mushonga wawakakanganwa.
Ko kana ndikatora mushonga wakawandisa?
Kana uchifunga kuti watora mushonga unopfuura wakatarwa, fonera National Poisons Information Centre paColombo National Hospital nekukasika. Kana zvisina kudaro, enda kuEmergency Treatment Unit (ETU) yechipatara chiri pedyo nekukurumidza.
Mimwe mishonga inogona kushanda pamwe chete neVoxelotor
Mimwe mishonga yauri kutora inogona kukanganisa mashandiro anoita Voxelotor. Voxelotor inogonawo kuchinja mashandiro anoita mimwe mishonga. Saka, udza chiremba wako nezvemishonga yese yauri kutora (kusanganisira mavhitamini, mishonga yemishonga, uye zvinowedzera) .
| Rudzi rwemushonga | Cherechedza |
|---|---|
| Mishonga inorwisa fungus (semuenzaniso fluconazole, ketoconazole) | Izvi zvinogona kuwedzera huwandu hweVoxelotor mumuviri. |
| Mishonga yeTB (semuenzaniso `rifampin`) | Izvi zvinogona kuderedza kushanda kweVoxeletor. |
| Kurapwa neHIV (semuenzaniso efavirenz) | Mhedzisiro yeVoxeletor inogona kukanganiswa. |
| Mimwe mishonga yekunyaradza (semuenzaniso midazolam) | Voxelotor inogona kuchinja mhedzisiro yemishonga iyi. |
Rondedzero iyi haina kukwana. Saka udza chiremba wako nezvemishonga yese yaunotora, kana uchisvuta, uye kana uchinwa doro.
Migumisiro inogona kuitika nekuda kwemushonga uyu
Kufanana nemushonga upi zvawo, Voxelotor inogona kukonzera migumisiro yakaipa kune vamwe vanhu. Mimwe yeiyi inogona kuva nengozi, saka zvakakosha kuti uizive.
| Migumisiro yakakomba inofanira kuziviswa kuna chiremba nekukasika | |
|---|---|
| Kusawirirana neAllergy | Mapundu paganda, kuvaviwa, kuzvimba kwemiromo, rurimi kana kumeso, kuoma kufema. |
| Zviratidzo zveKuvhara Ropa | Kurwadziwa pachipfuva kamwe kamwe, kunetseka kufema, kurwadziwa kamwe kamwe, kuzvimba, kana kutsvuka kwegumbo. |
| Migumisiro isingawanzova nengozi, asi inofanira kutaurwa kuna chiremba kana ikaramba iripo | |
| Matambudziko ekugaya chikafu | Kurwadziwa kwemudumbu, manyoka, kuda kurutsa. |
| Zvimwe zvidiki zvinokanganisa | Musoro, kuneta, fivha. |
Kana ukaona zvimwe zviratidzo zvisingawanzoitiki zvisina kutaurwa pane urongwa uhwu, taura nachiremba wako nezvazvo zvakare.
Ndinofanira kuchengeta mushonga uyu sei?
- Chengeta kure nevana vadiki .
- Chengeta patembiricha yemumba, pasi pe30 degrees Celsius (86 degrees Fahrenheit). Dzivirira kubva pakupisa kwakanyanya uye hunyoro.
- Rasa mushonga wapera usina kuushandisa.
Mharidzo Yekuenda Nayo Kumba
- Voxelotor mushonga unokosha unodzivirira masero matsvuku eropa kuti asachinje chimiro chechirwere chesickle cell uye unoderedza matambudziko echirwere.
- Usati watanga mushonga uyu, udza chiremba wako nezveruzivo rwese rwehutano hwako pamwe nemimwe mishonga yese yauri kutora.
- Medza piritsi rese, usingarityore, kuripwanya, kana kuritsenga. Inwa mushonga wakanyorwa panguva yakatarwa.
- Kana ukasangana nematambudziko akakomba akadai sekuzvimba kwechiso, kuoma kufema, kana kurwadziwa pachipfuva, tsvaga rubatsiro rwechiremba nekukasika.
- Mushonga uyu ndewako chete. Usambougovana nevamwe. Kana uine matambudziko, gara uchitaura nachiremba wako.
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