Masifunde ngakumbi ngehomoni iLeptin, ekuncedayo ukulawula ubunzima bakho.

Ngaba wakha wazibuza ukuba kutheni silamba, indlela esiziva ngayo sihluthi emva kokutya, kwaye kutheni kulula kwabanye ukutyeba ngelixa kunzima kwabanye ukwehlisa umzimba? Namhlanje siza kuthetha ngesithunywa sekhemikhali esincinci esiveliswa ngaphakathi emizimbeni yethu esinxulumene nazo zonke ezi zinto. Sibizwa ngokuba yiLeptin. Ngokuchanekileyo, i-leptin yi-hormone ekhutshwa ziiseli zethu zamafutha (izicubu zamafutha) ezisinceda sigcine ubunzima bomzimba wethu ixesha elide.

Yintoni iLeptin? Makhe sijonge nje.

Khawuthelekelele ukuba amafutha omzimba wakho avelisa i-hormone ebizwa ngokuba yiLeptin. Ngoko ke, umsebenzi ophambili weLeptin kukulawula indlala yethu nokusinika ukuziva "ndanele, ndihluthi" (ndihluthi) emva kokutya. Kufana nomphathi omncinci olawula ubunzima bomzimba wethu.

Izazinzulu zafumanisa i-hormone leptin ngo-1994. Oko kuthetha ukuba kusekho okuninzi ekufuneka kufundwe ngayo. Sele bephanda ukuba i-leptin ingasetyenziselwa na ukunyanga ukunciphisa ubunzima, isifo sika-Alzheimer, impilo yokuzala, kunye nokungazali.

"Ah... ukuba i-leptin ilawula ubunzima, akufanele na nathi sikwazi ukulawula i-leptin?" unokucinga. Kodwa, inyaniso kukuba, le hormone ayilula ukuyilawula njengoko sifuna.

Yintoni eyenziwa yi-leptin emzimbeni wethu?

Umsebenzi ophambili weLeptin kukugcina ubunzima bomzimba wethu buzinzile. Ngokukodwa, inceda ukugcina ulungelelwano lwexesha elide phakathi kobungakanani bokutya esikutyayo kunye nendlela umzimba wethu osebenzisa ngayo amandla. Oko kukuthi, isinceda singalambi xa umzimba wethu ungawadingi amandla (iikhalori).

I-Leptin isebenza kakhulu kwi-hypothalamus, inxalenye yengqondo yethu elawula indlala yethu kunye nokulinganisela kwamandla. Nangona kunjalo, ii-receptors ezibuthathaka kwi-leptin zikwafumaneka nakwezinye iindawo zomzimba wethu.

Kodwa nantsi into ekufuneka siyiqonde. I-Leptin ayisiyo i-hormone esenza silambe emva kokutya isidlo esinye. Endaweni yoko, isinceda sigcine ubunzima bethu ngokutshintsha ubungakanani bokutya esikutyayo ngokuhamba kwexesha , silawule indlela esisebenzisa ngayo amandla, kwaye isincede silawule ubunzima bethu.

Iziphumo zeLeptin zivakala ngakumbi xa uzama ukunciphisa umzimba. Cinga ngako, xa amafutha omzimba wakho ehla, amanqanaba akho e-leptin nawo ayancipha. Emva koko ingqondo ifumana isignali ethi, "Owu, umzimba awunakutya okwaneleyo, kufana nokuba sizila ukutya." Yiyo loo nto ngamanye amaxesha uziva ulambile kakhulu kwaye unqwenela ukutya okwahlukileyo. Emva koko ulingeka ukuba utye kakhulu. Oku kunokwenza kube nzima nangakumbi ukunciphisa umzimba.

Izazinzulu zisaphanda ngeLeptin. Zikholelwa ukuba iLeptin ikwachaphazela:

• I-Metabolism
• Inkqubo ye-endocrine - oko kukuthi, inkqubo yethu yehomoni
• Inkqubo yomzimba yokuzikhusela - inkqubo ekhusela kwizifo

Amanqanaba e-leptin alawulwa njani?

I-Leptin iveliswa kwaye ikhutshwa zizicubu ezimhlophe zamafutha emizimbeni yethu. Ezi zicubu ezimhlophe zamafutha lolona hlobo luphambili lwamafutha emizimbeni yethu. Ngamafutshane, ziindawo ezigcina amafutha emzimbeni wakho.

Ngenxa yokuba iLeptin iveliswa ziiseli zamafutha, ubungakanani beLeptin egazini lakho bunxulumene ngokuthe ngqo nobungakanani bamafutha emzimbeni wakho. Oko kuthetha ukuba, ukuba unamafutha omzimba amancinci, uneLeptin encinci. Ukuba unamafutha omzimba amaninzi, uneLeptin eninzi. Kulula, akunjalo?

Ukuba ubunzima bamafutha emzimbeni wakho buyanda ngokuhamba kwexesha, amanqanaba akho e-leptin aya kwanda. Ngokwahlukileyo koko, ukuba ubunzima bamafutha emzimbeni wakho buya kwanda, amanqanaba akho e-leptin aya kwanda.

Kuthekani ukuba i-leptin iyanda?

Amanqanaba eLeptin adla ngokuba phezulu kubantu abatyebe kakhulu. Oku kubizwa ngokuba yi-hyperleptinemia. Xa amanqanaba eLeptin ehlala ephezulu, iingqondo zethu zisenokungaphenduli kakuhle kwi-leptin. Oku kubizwa ngokuba yi -leptin resistance .

Kukho ezinye iimeko ezininzi ezinokunxulunyaniswa ne-hyperleptinemia:

• Uxinzelelo
• Ukuxhomekeka ekutyeni
• Iingxaki ze-Neurodegenerative
• Isifo sesibindi esinamafutha esinganxilisiyo
• Isifo sikaRabson-Mendenhall - Esi sisifo esingaqhelekanga kakhulu esibangelwa yimfuza.

Yintoni iLeptin Resistance?

Ukuba uneLeptin Resistance, ingqondo yakho ayiphenduli kwiLeptin ngokuqhelekileyo. Khawuthelekelele, iLeptin iqhubeka nokuthumela imiyalezo engqondweni isithi "Nditye ukutya okwaneleyo, ndihluthi," kodwa ingqondo ayibonakali ngathi ayinandaba. Ngoko ke, awuziva ugcwele. Ngenxa yesi sizathu, uyaqhubeka nokutya, nangona unamafutha amaninzi agcinwe emzimbeni wakho.

Ayisiyiyo loo nto kuphela, kodwa ngenxa yokuba iLeptin ayisebenzi kakuhle, ingqondo icinga ukuba umzimba uyalamba kwaye iyalamba. Emva koko, ukuze kongiwe amandla, ingqondo iyanciphisa amanqanaba ethu amandla, kwaye inciphise nenani leekhalori esizisebenzisayo xa siphumle. Ngamafutshane, iBasal Metabolic Rate (BMR) yethu iyancitshiswa.

Ngoko ke uyabona, ukumelana ne-leptin kukwenza uzive ulambile ngalo lonke ixesha, kwaye kunciphisa ne-BMR yakho. Xa ezi zinto zimbini zidibana, ukutyeba kuba mandundu nangakumbi.

Oososayensi okwangoku baphanda ngamayeza anokunyanga ukuxhathisa i-leptin.

Ziziphi iimpawu zeLeptin Resistance?

Iimpawu eziphambili zokunganyamezelani ne-leptin kukuziva ulambile kakhulu (hyperphagia) kunye nokutya kakhulu. Ezi mpawu zenzeka nokuba kukho amafutha amaninzi agcinwe emzimbeni.

Nangona kunjalo, kukho ezinye izinto kunye neemeko ezinokubangela ezi mpawu. Ukuxhathisa i-Leptin akukuphela kwayo. Njengoko izazinzulu zisafunda nge-leptin, kusenokwenzeka ukuba iimpawu ezingakumbi zokuxhathisa i-leptin ziya kufunyanwa kwixesha elizayo.

Kuthekani ukuba i-leptin iyancipha?

Ukunqongophala kwe-Leptin yimeko engaqhelekanga kakhulu. Isifo esiphambili esinxulunyaniswa nayo kukunqongophala kwe-leptin yokuzalwa. Le yimeko yemfuza ebakho xa umntu ezalwa. Abantu abanale meko abayivelisi i-leptin kwizicubu zabo zamafutha.

Xa i-leptin ingekho, umzimba ucinga ukuba akukho mafutha emzimbeni. Oku kubangela indlala engalawulekiyo kunye neminqweno yokutya. Ngenxa yesi sizathu, abantwana abazalwa benesifo se-leptin bakhula ngokutyeba kakhulu (ukutyeba kweklasi yesi-3) besebancinci kakhulu, kwaye ukufikisa kuyalibaziseka.

Ezinye izifo ezinokubangela esi sifo:

• I-Dyslipidemia - ukungalingani kwamafutha afana ne-cholesterol kunye ne-triglycerides
• Isifo sesibindi esinamafutha
• Usulelo oluqhelekileyo lweebhaktheriya
• I-Hyperinsulinemia - oko kuthetha ukuvelisa i-insulin eninzi kakhulu
• I-hypogonadotropic hypogonadism - oko kuthetha ukuba amanqanaba aphantsi eehomoni zesini

Luhlobo luni lovavanyo oluqhutywayo ukujonga amanqanaba e-leptin?

Amanqanaba eLeptin anokulinganiswa ngovavanyo lwegazi. Nangona kunjalo, oogqirha abaqhele ukuvavanya amanqanaba e-leptin yomntu wonke. Bacebisa uvavanyo lwe-leptin kwezi meko zilandelayo:

• Ukuba umntwana wakho omncinci unesifo sokutyeba kakhulu kwiklasi yesi-3 .
• Ukuba utyebile kakhulu kwaye ulambile rhoqo .

Afanele abe njani amanqanaba aqhelekileyo e-leptin?

Amanqanaba eLeptin ngokwesiqhelo angaqala ukusuka ku:

• Kwabasetyhini: 0.5 ukuya kwi-15.2 nanograms nge-milliliter (ng/mL)
• Kumadoda: 0.5 ukuya kwi-12.5 nanograms nge-milliliter (ng/mL)

Kodwa khumbula, ezi zigaba ziqhelekileyo zingahluka kancinci phakathi kweelabhoratri ezahlukeneyo. Ngoko ke, kungcono ukujonga uluhlu oluqhelekileyo kwingxelo yakho. Okanye, kungcono ukubuza ugqirha wakho ngalo mba.

Ndingawanyusa njani amanqanaba e-leptin yam?

Inyaniso kukuba, akukho nto ingako sinokuyenza ukwandisa amanqanaba ethu e-leptin ukunciphisa indlala kunye nomdla wokutya. Kuba, njengoko bekutshiwo ngaphambili, amanqanaba akho e-leptin anxulumene ngokuthe ngqo nobungakanani bamafutha onawo emzimbeni wakho.

Olunye uphando lufumanise ukuba abantu abalala kancinci banamanqanaba aphezulu e-ghrelin yehomoni yendlala kunye namanqanaba aphantsi ehomoni ye-leptin. Ngoko ke, ukulala ngokwaneleyo nomgangatho ofanelekileyo kunokunceda ekulawuleni iihomoni zakho.

Izazinzulu zikwaphanda ubudlelwane phakathi kwe-leptin nohlobo lwamafutha olubizwa ngokuba yi-triglycerides. Olunye uphando lubonise ukuba amanqanaba aphezulu e-triglyceride achaphazela indlela esebenza ngayo i-leptin. Kodwa kusekho izimvo ezahlukeneyo ngale nto. Ezinye izazinzulu zicinga ukuba isicwangciso sokutya esinciphisa i-triglycerides sinokunceda ukuphucula amanqanaba e-leptin. Kodwa abanye abavumelani.

Ziziphi ukutya okuneLeptin eninzi?

Kulapho abantu abaninzi benza khona impazamo. I-Leptin yi-hormone eveliswa emizimbeni yethu, ayisosondlo esinokusifumana ekutyeni okufana ne-vitamin C okanye iproteni. Ngoko ke, akukho nto ifana nokutya okune-leptin.

Okokugqibela, ezinye zezona zinto zibalulekileyo ekufuneka sizikhumbule

I-Leptin yinto entsha efunyenweyo, ngoko ke izazinzulu zisafunda okungakumbi ngayo, ingakumbi indlela echaphazela ngayo ukutyeba kakhulu kunye nokunciphisa umzimba. Njengoko ubona, njengoko umzimba wakho ulahlekelwa ngamafutha, amanqanaba e-leptin ayehla, nto leyo ebonisa ukuba umzimba wakho "uyazila ukutya," nto leyo eyenza kube nzima ukunciphisa umzimba.

Ukuba ukhathazekile ngobunzima bakho okanye ufuna ulwalathiso malunga nendlela yokunciphisa umzimba ngendlela enempilo, kungcono ukuthetha nogqirha wakho. Ungathetha nogqirha we-endocrinologist malunga neenkqubo zokulawula ubunzima.

Khumbula, konke oku kunokukunceda uhlale usempilweni. Kubalulekile ukuba uqaphele umzimba wakho.

I- Leptin, ulawulo lobunzima, iihomoni, indlala, ukutyeba kakhulu, amafutha, imetabolism