Ingxaki yentliziyo? Masifunde ngovavanyo lwe-BNP (B-type Natriuretic Peptide).

Ngaba wakha weva ngovavanyo lwe-BNP? Mhlawumbi ugqirha wakho ukuxelele ukuba ulwenze, okanye ubusoloko ulujonga xa uneengxaki zentliziyo. Namhlanje, siza kuthetha ngokuba olu vavanyo lwegazi lwe-BNP luyintoni, lunokukuxelela ntoni, lugqityiwe nini, kwaye ungatolika njani iziphumo.

Yintoni le BNP test?

Ngamafutshane, olu vavanyo lwe-BNP lulinganisa inqanaba lehomoni ekhethekileyo egazini lakho. Le homoni ibizwa ngokuba yi -B-type natriuretic peptide , okanye `(BNP)` ngamafutshane. Oku kunokunika ugqirha wakho umbono olungileyo wendlela intliziyo yakho esebenza ngayo.

Ukuba inqanaba le-`(BNP)` egazini lakho liphezulu kunesiqhelo, oko kuthetha ukuba intliziyo yakho ayisebenzi kakuhle, oko kuthetha ukuba ayimpompi igazi elaneleyo emzimbeni wakho wonke. Ngamanye amaxesha, le `(BNP)` isuswa emzimbeni zizintso, ngoko ke nokuba kukho ingxaki ngezintso, inqanaba le-`(BNP)` linokuba phezulu.

Enye into, ezinye iilabhoratri zenza uvavanyo olufanayo olubizwa ngokuba yi-'aminoterminal pro B-type natriuretic peptide'. Lufinyeziwe njenge-`(NT-proBNP)`. Zombini iimvavanyo ze-`(BNP)` kunye ne-`(NT-proBNP)` zibonelela ngolwazi olufanayo. Nangona kunjalo, ixabiso le-`(NT-proBNP)` linokuba phezulu ngokuphindwe kahlanu ukuya kwelishumi kune-`(BNP)`.

Oogqirha basebenzisa olu vavanyo ukuze bafumane ukuba unesifo sentliziyo . Ukuba sele unayo, ugqirha wakho uza kusebenzisa olu vavanyo ukuze abone ukuba sibi kangakanani na kwaye nokuba unyango lwakho luyasebenza na. Ngamanye amaxesha, ukuba kucingelwa ukuba usemngciphekweni omkhulu weengxaki zentliziyo, nabo banokwenza olu vavanyo.

Ngoko ke yintoni le BNP?

I-BNP yenye yeeproteni ezininzi ezinceda ekulawuleni ukuhamba kwegazi emizimbeni yethu. Nangona yenziwe yintliziyo, ngamanye amaxesha ibizwa ngokuba yi-'brain' natriuretic peptide kuba yafunyanwa okokuqala kwizicubu zobuchopho. Cinga ngayo, iyamangalisa, akunjalo?

Uyazi, intliziyo yethu kunye nemithambo yegazi zisebenza kunye ukupompa igazi elinomoya-mpilo emzimbeni wonke. I-ventricle yasekhohlo, enye yamagumbi amane entliziyweni, yiyo epompa uninzi lwegazi entliziyweni ize ilithumele emzimbeni. Oku kufana negumbi eliphambili lokupompa lentliziyo.

Le ventricle yasekhohlo yindawo ephambili yokuveliswa kwe-`(BNP)`. Xa umthwalo entliziyweni usanda, okanye xa intliziyo iphantsi koxinzelelo ngenxa yengxaki ethile, inqanaba le-`(BNP)` liyakhula. Iiseli zemisipha yentliziyo zisabela kolu xinzelelo ngokukhupha i-`(BNP).` Oku ke kunciphisa umthwalo entliziyweni kwaye kubonise izintso ukuba zisuse ityuwa namanzi emzimbeni. Yiloo nto igama elithi ``Natriuretic`` lithetha - lithetha into ekhawulezisa ukususwa kwe-sodium (ityuwa) namanzi emzimbeni.

Luvavanyo lwe-BNP lwenziwa nini?

Ugqirha wakho angayalela olu vavanyo ukujonga amanqanaba aphezulu e-BNP egazini lakho, nto leyo enokubonisa isifo sentliziyo .Ukuba kukho iimpawu zokusilela kwentliziyo, uvavanyo lwe-BNP okanye lwe-NT-proBNP ngokuqinisekileyo luya kwenziwa.

Makhe sibone ukuba zeziphi iimpawu zokusilela kwentliziyo.

• Kufana nokukhohlela okomileyo okuya kuba mandundu xa usiya kulala. Ngamanye amaxesha ungacinga ukuba ngumkhuhlane nje oqhelekileyo, kodwa wahlukile.
• Ubunzima bokuphefumla, ukuphefumla kancinci (Dyspnea), okanye ukuphefumla kancinci. Ukuba ufumana ukuphefumla kancinci nasemva kokwenza umsebenzi omncinci, kufuneka ukhathazeke.
• Ukuphambana kwengqondo, imeko yokudideka nokulahlekelwa zingqondo. Oku kunokwenzeka ngakumbi kubantu abadala.
• Ukuba nesiyezi, ukuquleka (iSyncope). Nikela ingqalelo koku nokuba uziva ubuthathaka, njengaxa uphakama ngequbuliso.
• Ndidinwe kakhulu, ndiziva ndingenabomi. Ukuba oku kudinwa akuphelanga nokuba sele ndilele kakuhle, yingxaki leyo.
• Ukubetha kwentliziyo kukubetha kwentliziyo okukhawulezayo ngendlela engaqhelekanga. Ukuba intliziyo yakho ibetha ngokukhawuleza okanye ivakala ngathi iyatsiba.
• Isicaphucaphu, ukuhlanza, ukungabi namdla wokutya.
• Ukudumba kwesisu, imilenze, amaqatha, kunye neenyawo (i-edema). Ukuba oku kudumba kufana namaqhuqhuva xa ukujongile, olo luphawu olukhethekileyo.
• Isidingo sokuchama rhoqo ebusuku (iNocturia).

Kubalulekile: Ukuba unayo nayiphi na kwezi mpawu, kubaluleke kakhulu ukufuna ingcebiso kagqirha ngoko nangoko. Ukungaphumeleli kwentliziyo yimeko esongela ubomi efuna unyango ngoko nangoko. Nceda ungazityesheli ezi mpawu.

Ukusilela kwentliziyo kuthetha ukuba intliziyo yakho ayimpompi igazi ngokufanelekileyo, kungekhona ukuba intliziyo yakho iyeke ngokupheleleyo. Khumbula ukuba ukuba sele uxelelwe ngugqirha ukuba unesifo sentliziyo, ugqirha wakho uya kuqhubeka nokusebenzisa olu vavanyo ukuze abone ukuba unyango lwakho lusebenza kakuhle kangakanani.

Olu vavanyo lwe-BNP (okanye i-NT-proBNP) luzichonga njani iingxaki zentliziyo?

Olu vavanyo lwe-`(BNP)` okanye uvavanyo lwe-`(NT-proBNP)` lulinganisa ubungakanani be-`(BNP)` hormone (okanye `(NT-proBNP)`) egazini lakho. Amanqanaba aphezulu ale hormone egazini athetha ukuba intliziyo kufuneka isebenze nzima ukupompa igazi. Ngamafutshane, intliziyo kufuneka isebenze nzima. Oku kuthetha ukuba izihlunu zentliziyo zoluliwe kwaye ziphantsi koxinzelelo.

Yintoni omele uyilindele xa ubhala uvavanyo?

Akukho nto ikhethekileyo ekufuneka uyenze ukuze ulungiselele olu vavanyo lwe-`(BNP)` okanye `(NT-proBNP)`. Akunyanzelekanga ukuba uzile ukutya, kwaye ungasela amanzi. Ugqirha okanye umongikazi wakho uza kucoca indawo efanelekileyo engalweni yakho aze afake inaliti. Ngoko ke, igazi elincinci liza kuthathwa emthanjeni. Usenokuziva intlungu encinci, njengokuhlaba, xa inaliti ifakwa. Kodwa ayibuhlungu kakhulu.

Emva koko, ilebhu iya kuvavanya isampuli yegazi lakho ukuze ibone ukuba ingakanani inqanaba lakho le-`(BNP)` (okanye `(NT-proBNP)`). Ugqirha wakho uya kukuxelela ngayo xa iziphumo zibuya.

Emva kokwenza uvavanyo?

Emva kokuba igazi litsaliwe, ugqirha okanye umongikazi uza kubeka ibhandishi encinci engalweni yakho. Usenokuziva ubuhlungu kancinci apho inaliti ifakwe khona. Usenokuziva unamanxeba amancinci, nto leyo eqhelekileyo. Xa iziphumo zibuya, ugqirha wakho uza kuthetha nawe ngazo aze axoxe ngento omawuyenze emva koko.

Zithini iingenelo zokuthatha olu vavanyo?

Khangela, olu vavanyo, oluthatha igazi elincinci kuphela, lunokuxelela ugqirha wakho ulwazi oluninzi olubalulekileyo malunga nempilo yentliziyo yakho. Uvavanyo olubizwa ngokuba yi-`(BNP)` okanye `(NT-proBNP)` lunokunceda ugqirha wakho ukuba afumanise ukuba unesifo sentliziyo na . Lunokuthintela nezinye izifo ezineempawu ezifanayo. Umzekelo, ukuphefumla okuncinci kunokubangelwa yingxaki yemiphunga. Olu vavanyo lunokukunceda uhlukanise phakathi kwezi meko zimbini. Iziphumo zolu vavanyo ziya kunceda ugqirha wakho ukuba acwangcise unyango lwakho aze abone ukuba unyango lusebenza kangakanani.

Ngaba kukho naziphi na iingozi ngolu vavanyo lwe-BNP?

Uvavanyo lwegazi luqhelekile kwaye lukhuselekile. Ugqirha ufuna igazi elincinci kuphela kolu vavanyo. Emva kovavanyo, umzimba wakho uya kuqala ukuvelisa igazi kwakhona. Abanye abantu banokuziva benesiyezi okanye bedidekile emva kokuba befumene igazi. Oku kuqhelekile. Uninzi lwexesha, olu luvo luyaphela kwimizuzu embalwa.

Kuthatha ixesha elingakanani ukufumana iziphumo zovavanyo lwe-BNP?

Oogqirha badla ngokwenza olu vavanyo xa uneempawu zokusilela kwentliziyo, nokuba ukwigumbi longxamiseko okanye esibhedlele. Kubalulekile ukufumanisa ukusilela kwentliziyo (nokususa ezinye iimeko) kwaye uqale unyango ngokukhawuleza.

Oku kuthetha ukuba uza kufumana iziphumo zovavanyo ngoko nangoko, ngesiqhelo kwimizuzu eli-15. Olu luvavanyo olukhawulezayo kakhulu. Ugqirha wakho uza kukuxelela ukuba iziphumo ziya kufumaneka nini kwaye ziya kuthetha ukuthini.

Kuthetha ukuthini ukuba nenqanaba le-BNP elingaqhelekanga?

Inqanaba eliqhelekileyo le-`(BNP)` kumntu ongenazo iingxaki zentliziyo lingaphantsi kwe-100 picograms nge-milliliter (`pg/mL`). Ukuba inqanaba le-`(BNP)` liphezulu kune-100 `pg/mL`, isenokuba luphawu lokusilela kwentliziyo.

Inqanaba eliqhelekileyo le-NT-proBNP lingaphantsi kwe-125 pg/mL kubantu abangaphantsi kweminyaka engama-75 ubudala kwaye lingaphantsi kwe-450 pg/mL kubantu abangaphezu kweminyaka engama-75 ubudala. Ukuba inqanaba le-NT-proBNP lingaphezulu kwe-900 pg/mL, linokuba luphawu lokusilela kwentliziyo.

Kodwa khumbula ukuba uluhlu oluqhelekileyo lwamanqanaba e-BNP okanye e-NT-proBNP lunokwahluka kumntu nomntu. Kungcono ukuthetha nogqirha wakho malunga namaxabiso akho ovavanyo, njengoko ugqirha wakho uya kuqwalasela nezinto ezifana neminyaka yakho kunye nezinye iimeko zempilo.

Usebenzisa ii-beta blockers, ii-ACE inhibitors, kunye ne-diuretics (amayeza akwenza ukhuphe umchamo omninzi) njengonyango lokusilela kwentliziyo.Ukuba uthatha izinto ezinje, amanqanaba akho e-BNP okanye e-NT-proBNP anokuba phantsi kunalawo omntu ongawasebenzisiyo loo mayeza. Kwakhona, ukuba utyebile kakhulu (amafutha amaninzi emzimbeni) okanye unesifo sezintso, la manqanaba anokuba phantsi kunesiqhelo.

Ngokuxhomekeke kwiziphumo zovavanyo lwe-BNP, ugqirha wakho unokuyalela ezinye iimvavanyo, ezifana ne- electrocardiogram (EKG okanye i-ECG) . Oku kubandakanya ukubeka ii-sensors eluswini lwakho ukuze zijonge umsebenzi wombane wentliziyo yakho, obizwa ngokuba kukubetha kwentliziyo yakho. Oku kunokunceda ugqirha wakho ukuba axilonge okanye ahlole ukusilela kwentliziyo okanye ezinye iimeko zentliziyo.

Ndingathetha nini nogqirha wam malunga novavanyo lwe-BNP (okanye lwe-NT-proBNP)?

Ukuba unemibuzo malunga neziphumo zovavanyo lwakho lwegazi lwe-BNP, qiniseka ukuba uthetha nogqirha wakho. Musa ukoyika ukubuza, "Gqirha, lithetha ukuthini eli xabiso kwingxelo yam ye-BNP?" Ugqirha wakho uza kukuchazela iziphumo. Baza kucebisa naluphi na olunye uvavanyo okanye unyango olunokufuneka.

Ngoko ke, zeziphi izinto ezibalulekileyo ekufuneka sizikhumbule kweli nqaku?

Uvavanyo lwe-B-type natriuretic peptide (BNP), olukwaziwa ngokuba luvavanyo lwe-aminoterminal pro B-type natriuretic peptide (NT-proBNP), luvavanyo olunika ugqirha wakho ulwazi olubalulekileyo malunga nempilo yentliziyo yakho. Lunokunceda ekuxilongeni iimeko ezifana nokusilela kwentliziyo , ucebe unyango ngokufanelekileyo, kwaye ubone ukuba olo nyango lusebenza kangakanani.

Ukuba unemibuzo malunga neziphumo zovavanyo lwakho, ungathandabuzi ukuthetha nogqirha wakho. Ukuba ufunyaniswe unentliziyo engasebenzi kakuhle, kukho izinto onokuzenza ukuze uphile nayo. Oku kuquka utshintsho kwindlela ophila ngayo, utshintsho kwindlela otya ngayo (njengokunciphisa ityuwa namanzi), ukuzilolonga, kunye nokuthatha amayeza akho njengoko kuyalelwe .

Ngoko ke, kubaluleke kakhulu ukunyamekela intliziyo yakho. Ukuqaphela iimvavanyo ezinjalo kuya kuba luncedo kakhulu kuwe. Ngamana ungafumana amandla okugcina intliziyo yakho iphilile!

I- BNP, i-NT-proBNP, ukusilela kwentliziyo, isifo sentliziyo, uvavanyo lwegazi, iimpawu zesifo sentliziyo, impilo yentliziyo