Ukuba wena okanye umntwana wakho une-Beta Thalassemia, siyazi ukuba ubomi bunokuba nzima kangakanani. Ukufuneka utofelwe igazi rhoqo kwaye uphile neengxaki ezihambisana nalo akulula. Kodwa namhlanje, ngokuhambela phambili kwesayensi yezonyango, siza kuthetha ngendlela yonyango enokuyinyanga ngokupheleleyo le sifo. Oko kukufakelwa kweeseli ze-stem, okanye njengoko abantu abaninzi besazi, "Ukufakelwa kweeseli ze-stem".
Ngamafutshane, yintoni ukufakelwa kweeseli ze-stem?
Masiqonde oku ngokulula. Khawucinge ukuba imizimba yethu inefektri yokwenza igazi. Siyibiza ngokuba yi -bone marrow . Le yinxalenye enesiponji ngaphakathi kwamathambo ethu amakhulu. Kwi-thalassemia, okwenzekayo kukuba ezinye zeemashini (iiseli) kule fektri, oko kukuthi, kwi-bone marrow, azisebenzi kakuhle. Ngoko ke, azivelisi iiseli zegazi ezibomvu ezilungileyo nezisempilweni ngokwaneleyo.
Kwi-stem cell transplant, iiseli zomzimba wakho ezingasebenzi kakuhle ziyasuswa kwaye zithatyathelwe indawo ziiseli ze-blood stem (iiHematopoietic Stem Cells) kumntu ophilileyo. Ezi seli zintsha zifana nomzi-mveliso omtsha. Ziya kumongo wakho wethambo kwaye ziqale ukwenza iiseli zegazi ezibomvu eziphilileyo.
Oko kukuthi, kufana nokulahla oomatshini abadala, abangasebenziyo, ukufaka oomatshini abatsha kraca, uze uqalise umzi-mveliso kwakhona.
Le nkqubo yokufakelwa kwesisu yenzeka njani?
Oku kwenzeka ngamanyathelo aliqela.
Ngaphambi kokufakelwa kwenye indawo
Okokuqala, kufuneka utshabalalise iiseli ezindala zomongo wamathambo ezingasebenzi kakuhle emzimbeni wakho. Yiyo loo nto isetyenziselwa i-chemotherapy . Igama elithi "chemo" lisenokuboyikisa abanye abantu, kodwa apha lisetyenziselwa ukwenza indawo kumongo wamathambo ukuze iiseli ezintsha neziphilileyo zingene zihlale. Kufana nokususa lonke ukhula oludala nokulungisa umhlaba ngaphambi kokutyala.
Ngexesha lokufakelwa
Olu ayilotyando lukhulu njengoko unokucinga. Kufana nje nokunikela ngegazi. Iiseli ze-stem ezivela kumntu onikelayo zifakwa emzimbeni wakho ngetyhubhu yeplastiki (i-catheter) efakwa esifubeni sakho. Ezi seli zihamba ngegazi lakho, zifumane indawo yazo kumongo wethambo, zize zihlale apho. Kuphela emva koko ziqala ukwenza iiseli zegazi eziphilileyo.
Sizifumana phi ezi seli?
Le yeyona nxalenye ibalulekileyo neyinzima yolu nyango. Asinakuthatha iiseli kuye nabani na. Ukuhambelana kwemfuza phakathi komnikeli nommkeli kufuneka kube phezulu kakhulu.
- Eyona midlalo ifanelekileyo:Oyena mntu unikelayo koku ngumzalwana okanye udade bomguli. Banamathuba amaninzi okuba nemfuza efanelekileyo.
- Ezinye iindlela: Kodwa ungalahli ithemba lokuba awukamfumani umntakwenu ofana nowakho. Kukho amathuba okufumana i-genetic match ngokusebenzisa iirejista zabaxhasi bamazwe ngamazwe, nokuba awuzalani. Oku kunokuba yinkqubo ethatha ixesha.
Zithini iingozi zolu nyango?
Njengakwezinye iindlela zonyango ezinkulu, kukho iingozi ezithile. Kubalulekile ukuxoxa ngazo ngokukhululekileyo nogqirha wakho.
| Umngcipheko | Ingcaciso elula |
|---|---|
| Umonakalo wamalungu omzimba | Ukuba ubungakanani besinyithi emzimbeni buyanda ngenxa yokufakwa igazi rhoqo kwaye amalungu anjengentliziyo nesibindi ayonakaliswa, umngcipheko unokwanda nangakumbi emva kokufakelwa. Yiyo loo nto kubalulekile ukuba unyango lwe-chelation lwenziwe ngokuchanekileyo ngaphambi kokufakelwa. |
| Isifo se-Graft vs. Host (GVHD) | Okwenzekayo kule meko kukuba iiseli zomnikeli, ezisandula ukungeniswa emzimbeni, ziyawubona umzimba wesigulana 'njengotshaba' kwaye ziwuhlasele. Kukho amayeza okulawula oku. |
| Iintsholongwane | Amayeza asetyenziswa ukulawula i-GVHD kunye ne-chemotherapy enikwa ngaphambi kokufakelwa anciphisa amasosha omzimba. Oku kwenza kube lula ukuba ufumane usulelo lweentsholongwane. Nangona kunjalo, oogqirha baya kukunika amayeza anjengee-antibiotics ukuthintela oku ngeli xesha. |
Okubalulekileyo kukuba, olu nyango lunokwenzeka ukuba luphumelele kubantu abancinci, ingakumbi abantwana abangaphantsi kweminyaka eli-14 ubudala. Kwakhona, ukuba umonakalo omncinci kumalungu omzimba ngaphambi kokufakelwa, kokukhona iziphumo zingcono.
Iziphumo ebezingalindelekanga ezinokwenzeka emva konyango
Kukho iziphumo ezininzi ezingalindelekanga zexesha elifutshane nezexesha elide ezinokwenzeka emva kokufakelwa isidoda.
Eyona nto ibalulekileyo yimpembelelo kumandla okufumana abantwana (Ukungazali) . I-chemotherapy ephezulu enikwa ngaphambi kokufakelwa inokuthi yonakalise ama-ovari abafazi kunye nokuveliswa kwesidoda kumadoda. Kodwa ngoku kukho nezisombululo zoku. Amadoda angayigcina isidoda sabo kwaye abafazi bangayigcina amaqanda abo (ukuqandisa isidoda/iqanda) ngaphambi konyango. Kubalulekile ukuthetha nogqirha wakho ngale nto kwangaphambili kwaye ufumane ingcebiso.
Ukongeza, oku kulandelayo kunokwenzeka emva nje kokufakelwa:
- Intlungu yomlomo okanye yomphimbo
- Isicaphucaphu nokuhlanza
- Ukopha okanye ukukrwela
- Ukudumba kwemiphunga
Kuthatha malunga neeveki ezi-2 ukuya kwezi-6 ukuba ezi stem cells zihambe ziye kumongo wethambo, ziqale ukusebenza, kwaye zibuyisele inani leeseli egazini lakho kwimeko eqhelekileyo. Iqela lezonyango liza kukujonga ngokusondeleyo ngeli xesha. Ngoko ke akukho nto inokubangela uxhalabo ngayo.
Umyalezo Wokuya Ekhaya
- Ukufakelwa kweeseli zesiqu lunyango olunokunyanga ngokupheleleyo i-beta thalassemia, kodwa alufanelekanga kuye wonke umntu.
- Oku kuquka ukutshintsha iiseli zomongo wethambo ezinezifo ngeeseli ze-stem ezifunyenwe kumntu ophilileyo.
- Oyena mntu unikelayo ufanelekileyo ngumzalwana okanye udade bomguli, kodwa nabanye abanikelayo banokufumaneka.
- Ngenxa yokuba kukho iingozi kunye nemiphumo emibi, kubalulekile ukuxoxa ngazo zonke iinkalo kakuhle nogqirha wakho ngaphambi kokuba uthathe isigqibo malunga nolu nyango.
- Olu nyango luhlala luphucuka, ngoko ke hlala unethemba ngekamva.
💬 Comments (0)
Akukho zimvo zithunyelweyo okwangoku. Faka uluvo lwakho apha okokuqala.
Faka uluvo lwakho