Umele ukuba ukhe weva oomama bethu, ootata, oomakhulu, kunye nootatomkhulu bethu besithi, "Owu, umzimba wam ubuthathaka ngoku," kwaye "Amathambo am abuthathaka." Enyanisweni, njengoko sikhula, amandla emizimba yethu ayancipha, kwaye amandla amathambo ethu ayancipha kancinci kancinci. Ngamanye amaxesha, xa le meko iba mandundu, nokuba ukuwa okuncinci okanye nokuvuka ebhedini kunokukhokelela kumngcipheko omkhulu wokuphuka ingalo okanye umlenze. Le meko apho amathambo aba buthathaka kwaye abuthathaka ibizwa ngokuba yi-osteoporosis . Ngoko ke, namhlanje siza kuthetha ngodidi olubaluleke kakhulu lwamayeza asetyenziswa ngoogqirha ukulawula olu hlobo lobuthathaka bamathambo.
Ngamafutshane, zithini ezi bisphosphonates?
IiBisphosphonates ludidi lwamayeza asetyenziselwa ukunyanga izifo ezifana ne-osteoporosis ezinciphisa uxinano lwamathambo kunye namandla. Oku kuthetha ukuba akukho chiza linye elibizwa ngeli gama, kodwa lidibaniso lwamayeza aliqela. Ukongeza kwi-osteoporosis, oogqirha bakwanika eli chiza kwiimeko ezithile zamanqanaba aphezulu e-calcium egazini (hypercalcemia).
Makhe sijonge iintlobo eziphambili zamayeza phantsi kolu didi. La aza ngeendlela ezimbini eziphambili. Elinye lithathwa ngomlomo (iipilisi zithathwa ngomlomo), elinye lifakwa ngemithambo yegazi (IV) (ulwelo olufakwa emthanjeni).
| Indlela yokunika amayeza | Imizekelo yamayeza (asetyenziswa kakhulu eSri Lanka) |
|---|---|
| IiBisphosphonates zomlomo | I-Alendronate, iRisedronate, i-Ibandronate |
| Iifluid ezifakwa emthanjeni (ii-IV Bisphosphonates) | I-Zoledronic acid, iPamidronate |
Eli yeza lichaphazela njani umzimba?
Ukuze sikuqonde oku, kufuneka siqale siqonde kancinci ngendlela amathambo ethu asebenza ngayo. Cinga ngamathambo ethu njengesakhiwo esihlala silungiswa. Imizimba yethu iyaqhekeka ngokwendalo ize isuse amathambo amadala, abuthathaka. Le nkqubo ibizwa ngokuba yi-bone resorption.Kwangaxeshanye, kwakheka ithambo elitsha nelinamandla kwiindawo apho lisuswe khona. Logama nje ezi nkqubo zimbini zilingana, amathambo ethu ahlala eqinile.
Nangona kunjalo, njengoko sikhula, ingakumbi emva kokuya exesheni kwabasetyhini, olu lungelelwaniso luyalahleka. Okwenzekayo kukuba ithambo elidala liqhekeka ngokukhawuleza kakhulu kunokuba ithambo elitsha lenziwa. Isiphumo kukuba amathambo aya encipha kancinci kancinci, abe neembobo ngakumbi, kwaye abe buthathaka.
Ngoko ke, into eyenziwa zezi bisphosphonates kukulawula kakhulu nokunciphisa izinga lokufunxwa kwamathambo. Emva koko, ngenxa yokuba ithambo elidala liqinile ngelixa kwakhiwa ithambo elitsha, uxinano kunye namandla amathambo ayanda. Ngamafutshane, ayayeka ukulahleka kwamathambo.
Zeziphi iimeko ezisetyenziselwa ii-bisphosphonates?
Oogqirha bacebisa kakhulu eli yeza kwezi meko zilandelayo:
- I-Osteoporosis yimeko eyenzeka kubafazi emva kokuya exesheni.
- I-Osteoporosis kumadoda.
- Ukuthintela ukwenzeka kwe-osteoporosis.
- I-Osteoporosis ebangelwa kukusetyenziswa rhoqo kwamayeza anjenge-steroids (glucocorticoids).
- Isifo sethambo sikaPaget sisifo apho amathambo akhula ngendlela engaqhelekanga.
- Lawula iingxaki ezenzeka kwiintlobo ezithile zomhlaza (umz. iMultiple Myeloma) naxa iiseli zomhlaza zisasazeka ziye emathanjeni (Bone Metastasis).
- Ukulawula i-hypercalcemia enxulumene nomhlaza (ukwanda kwamanqanaba e-calcium egazini ngenxa yomhlaza).
Ndingayisebenzisa njani le yeza? Oku kubaluleke kakhulu!
Kubalulekile ukulandela le miyalelo ngokuchanekileyo ukuze ufumane iingenelo ezipheleleyo zeyeza kwaye unciphise iziphumo ebezingalindelekanga.
Amayeza Omlomo
Indlela yokusela ezi pilisi icacile kakhulu. Kufuneka ulandele imiyalelo kagqirha ngokuchanekileyo.
- Le pilisi kufuneka ithathwe kusasa, ngaphambi kokuba itye okanye isele nantoni na (ingatyiwa) .
- Ipilisi mayithathwe kuphela neglasi epheleleyo yamanzi (amanzi aqhelekileyo) . Akuvumelekanga ngokupheleleyo ukusela eli yeza nezinto ezifana neti, ikofu, ubisi, okanye iziselo zeziqhamo.
- Eyona nto ibalulekileyo: Emva kokusela iyeza, kufuneka uhlale okanye ume ubuncinane imizuzu engama-30 ukuya kwengama-60 . Musa ukugoba, ukulala phantsi, okanye ukulala nangasiphi na isizathu.
- Isizathu soku kukuba eli yeza linokonakalisa umphimbo. Loo ngozi iyaphela xa usukuma kuba iyeza lingena ngokukhawuleza esiswini.
- Akuyonto ilungileyo ukutya okanye ukusela nantoni na enye ngeli xesha lemizuzu engama-30-60. Emva kokuba elo xesha liphelile, ungatya isidlo sakusasa njengesiqhelo.
Amayeza e-IV
Awunakukwenza oku ekhaya. Olu nyango lunikwa esibhedlele okanye eklinikhi. Ngokuxhomekeke kwimeko yakho, olu tyando (i-infusion) ludla ngokunikwa kube kanye ngonyaka okanye rhoqo emva kweenyanga ezimbalwa.
Ngelixa usebenzisa eli yeza, ugqirha wakho udla ngokucebisa ukuba utye ukutya okutyebileyo kwi-calcium (ubisi, iyogathi, itshizi, intlanzi encinci) kwaye uthathe isongezelelo se-vitamin D , njengoko zombini zibalulekile kumathambo aqinileyo.
Zithini iziphumo ebezingalindelekanga ze-bisphosphonates?
Njengakweminye imithi, kusenokubakho iziphumo ebezingalindelekanga. Kodwa ungakhathazeki, uninzi lwazo zincinci.
| Uhlobo lweyeza | Iziphumo ebezingalindelekanga ezinokubakho |
|---|---|
| Amayeza omlomo | Iingxaki zesisu ezifana nesitshiso sentliziyo, i-GERD, i-esophagitis, iintlungu zesisu, kunye nezilonda. (Ezi zinokuthintelwa kakhulu ngokulandela indlela echanekileyo yokusela amayeza akho.) |
| Amayeza e-Intravenous (IV) | Iimpawu ezifana nezomkhuhlane okanye umkhuhlane, ezinje ngomkhuhlane, iintlungu zomzimba, intloko ebuhlungu, kunye nentlungu yamalungu kunye nemisipha, zinokwenzeka emva kosuku okanye ezimbini emva kokusela iyeza. Ezi zihlala ziphela kwiintsuku ezimbalwa. |
Iziphumo ebezingalindelekanga ezingaqhelekanga kodwa ezifanelekileyo ukuzazi
Nangona ezi zinqabile kakhulu , kubalulekile ukuba uzazi.
- I-Osteonecrosis yomhlathi: Le ngozi incinci kakhulu, ingakumbi emva kotyando olufana nokukhupha amazinyo. Ngoko ke ukuba usebenzisa la mayeza, xelela ugqirha wamazinyo rhoqo xa umbona.
- Ukuqhekeka kwe-femur okungaqhelekanga: Oku kuyinto engaqhelekanga kubantu abasebenzisa eli yeza ixesha elide (ngaphezu kweminyaka emi-3-5).
- Iingxaki zamehlo: Ukudumba (i-uveitis, i-scleritis) kwiindawo ezahlukeneyo zeliso kunokwenzeka.
Eyona nto ibalulekileyo kukuba umngcipheko wokwaphuka kwethambo ngenxa ye-osteoporosis ukuba awusebenzisi eli yeza ungaphezulu ngokuphindwe kaliwaka kunomngcipheko omncinci kakhulu wezi ziphumo ebezingalindelekanga. Ngoko ke, kubaluleke kakhulu ukulandela imiyalelo kagqirha wakho.
Ufuna ukuphinda umbone ugqirha kwakhona nini?
Ukuba usebenzisa eli yeza, kubalulekile ukubona ugqirha wakho rhoqo ukuze ujonge ukuba iyeza liyasebenza na kwaye kukho naziphi na iziphumo ebezingalindelekanga. Ungathunyelwa kwingcali yamathambo (i-Endocrinologist okanye i-Rheumatologist).
Ugqirha wakho unokucebisa ukuba uskene i-DXA ukuze ubone ukuba amathambo akho aqinile kangakanani.
Inqaku Elikhethekileyo: Ukuba ubusebenzisa eli yeza iminyaka engaphezu kwemithathu kwaye ufumana iintlungu ezintsha ethangeni okanye emqolo wakho, musa ukuzityeshela kwaye wazise ugqirha wakho ngoko nangoko.
Umyalezo Wokuya Ekhaya
- IiBisphosphonates ziyindlela esebenzayo kakhulu yokunceda ukuqinisa amathambo abuthathaka ngenxa ye-osteoporosis.
- La mayeza asebenza ngokunciphisa izinga lokulahlekelwa ngamathambo.
- Xa usela amayeza okusela, kubalulekile ukuwasela ungenanto esiswini, ngamanzi kuphela, kwaye uhlale ume okanye uhleli imizuzu engama-30-60 emva kokusela amayeza.
- Nangona iziphumo ebezingalindelekanga ezincinci zinokubakho, iziphumo ebezingalindelekanga ezibi kakhulu azifumaneki. Iingenelo zamayeza zingaphezulu kakhulu kuneengozi.
- Ukuba unemibuzo, iinkxalabo, okanye amathandabuzo malunga nale mithi, thetha nogqirha wakho ngayo ngokukhululekileyo. Ungaze uyeke ukuthatha amayeza akho ngaphandle kwengcebiso kagqirha.
💬 Comments (0)
No comments yet. Be the first to share your thoughts here.
Add Your Comment