Ngaba wakha wamiselwa amayeza ngugqirha xa uneengxaki ezifana nokudakumba okanye ixhala? Ukuba kunjalo, kusenokwenzeka ukuba ukhe weva ngamayeza abizwa ngokuba yi-'Celexa' okanye 'Lexapro'. La ngamayeza amabini aqhelekileyo asetyenziswa kwezi meko kwihlabathi liphela nakwilizwe lethu. Ngoko ke, umbuzo abantu abaninzi abanawo ngowokuba yintoni umahluko phakathi kwala mayeza mabini, ingaba ayafana, kwaye ngowuphi ofanelekileyo kum. Masithethe ngale nto namhlanje ukuze sisuse onke amathandabuzo onawo engqondweni yakho.
Okokuqala, masibone ukuba yintoni iCelexa kunye neLexapro.
Ngamafutshane, omabini la mayeza akwiqela elibizwa ngokuba zii-antidepressants . Ngokuchanekileyo, avela kwiqela elithile lamayeza abizwa ngokuba yi-``SSRIs`` (Selective Serotonin Reuptake Inhibitors). Nangona igama lisenokuvakala liyinkimbinkimbi kancinci, inkqubo ilula kakhulu.
Khawucinge ukuba kukho abathunywa ngaphakathi kwengqondo yethu abathwala ulwazi besiya phambili nangasemva. Aba bathunywa sibabiza ngokuba zii-neurotransmitters. I-Serotonin sisithunywa esibaluleke kakhulu esilawula izinto ezifana neemvakalelo zethu, indlela esiziphatha ngayo, kunye nenkumbulo. Kwiimeko ezifana nokudakumba, eli nqanaba le-Serotonin linokwehla.
Oko kwenziwa yi-SSRIs kukuthintela le serotonin yesithunywa ukuba ingaphindi ifunxwe ngokukhawuleza emva kokuba yenziwe. Emva koko i-serotonin ihlala kwiiseli zemithambo-luvo yengqondo ixesha elide. Oko kuthetha ukuba umyalezo "wolonwabo" uhlala usebenza ixesha elide. Kulapho imeko yethu iqala ukuphucuka.
I-Celexa ligama lophawu lweyeza iCitalopram . I-Lexapro ligama lophawu lweyeza i- Escitalopram . Zombini zivunyiwe ukunyanga isifo sokudakumba esikhulu (MDD) kubantu abadala, ngelixa iLexapro ivunyiwe ukunyanga isifo sokuxhalaba ngokubanzi (GAD).
Kulungile, ngoko ke yintoni umahluko omkhulu phakathi kwezi zimbini?
Le yinyani enomdla kakhulu. I-'Citalopram' (iCelexa) kunye ne-'Escitalopram' (iLexapro), ngokweekhemikhali, ziyimifanekiso esipilini yemolekyuli enye. Njengesandla sethu sasekhohlo nesandla sethu sasekunene. Zombini zizandla, kodwa zahlukile. Kwikhemistri, ezi zibizwa ngokuba yi-'enantiomers'.
- I-Citalopram (iCelexa) yindibaniselwano yeendlela "zesandla sasekhohlo" kunye "nesandla sasekunene" ozikhankanyileyo.
- I-Escitalopram (Lexapro) yeyona isebenza kakhulu kwezi zimbini, oko kuthetha ukuba liyeza elenziwe ngenxalenye ephambili kuphela, njenge "sandla sasekunene".
Yingakho kukho umahluko omncinci kwindlela la mayeza mabini asebenza ngayo emizimbeni yethu.
Ngamafutshane, i-Escitalopram (Lexapro) ifana nenguqulelo yeCitalopram (Celexa) ephucukileyo nejolise kuyo.
Makhe sijonge ezinye zezona zinto ziphambili ezibangela umahluko:
- Ukusetyenziswa okuvunyiweyo: Nangona i-'Citalopram' ivunyiwe kuphela kuxinzelelo kubantu abadala, i-'Escitalopram' ivunyiwe kuxinzelelo kubantu abadala nakubantwana abaneminyaka engaphezu kwe-12 ubudala, kunye nokuxhalaba kubantu abadala nakubantwana abaneminyaka engaphezulu kwe-7 ubudala.
- Ukusebenza kakuhle: Ezinye izifundo zibonise ukuba i-Escitalopram isebenza ngcono kancinci kune-Citalopram ekulawuleni iimpawu zokudakumba.
- Umngcipheko wokubetha kwentliziyo: Zombini ezi ziyobisi zinokuba nefuthe elincinci kumsebenzi wombane wentliziyo. Oku kubizwa ngokuba yi-'QT prolongation'. Oku kunomngcipheko omncinci wokubetha kwentliziyo okungaqhelekanga. Nangona kunjalo, lo mngcipheko uphezulu kancinci nge-'Citalopram' kune-'Escitalopram', ingakumbi xa kusetyenziswe iidosi eziphezulu.
Iziphumo ebezingalindelekanga kunye nezinto ekufuneka uzazi
Ekubeni omabini la mayeza ekwintsapho enye, iziphumo ebezingalindelekanga nazo ziyafana kakhulu. Asinguye wonke umntu ozifumanayo, kodwa zihlala ziphela emva kwexesha elithile njengoko umzimba uqhelana namayeza.
| Iziphumo eziqhelekileyo zeCelexa kunye neLexapro | |
|---|---|
| Iziphumo ebezingalindelekanga eziqhelekileyo | |
| Iingxaki zokulala | Ukuva ulele emini okanye ukungakwazi ukulala ebusuku |
| Ukudinwa komzimba | Ukudinwa, isiyezi |
| Ezinye iimpawu eziqhelekileyo | Ukudinwa, intloko ebuhlungu, ukubila okugqithisileyo, umlomo owomileyo |
| Iingxaki zenkqubo yokugaya ukutya | Isicaphucaphu, ukuhlanza, ukuqhina, okanye urhudo |
| Iingxaki zomsebenzi wesondo | Ukuncipha komnqweno wesondo, ubunzima bokufikelela kwi-orgasm, ukulibaziseka kokuphuma kwesisu |
| Iziphumo ebezingalindelekanga ezingaqhelekanga kodwa ezinokuba yingozi | |
| Utshintsho kwisantya sentliziyo | Imeko ye-`QT Prolongation` ekhankanyiweyo apha ngasentla (kukho umngcipheko ophezulu kancinci ngeCitalopram) |
| Ukwehla kwamanqanaba e-sodium egazini | Ingabangelwa yimeko ebizwa ngokuba yi-"SIADH", ingakumbi kubantu abaneminyaka engaphezu kwama-65 ubudala. |
'I-Serotonin Syndrome' yimeko efuna ingqalelo ekhethekileyo.
Le yinto ekufuneka uyazi ngokuqinisekileyo . I-Serotonin Syndrome linqanaba eliphezulu le-serotonin emzimbeni. Oku kunokwenzeka kakhulu xa uqala ukuthatha amayeza, xa unyusa umthamo, okanye xa uwathatha kunye namanye amayeza achaphazela amanqanaba e-serotonin (umz., amanye amayeza e-migraine, amanye amayeza okudakumba).
Ukuba wena okanye umntu omaziyo ufumana ezi mpawu ngaxeshanye, yiya kwiSebe lezeMpilo eziNgxamisekileyo (ETU) esibhedlele ngoko nangoko.
- Ukungazinzi, ukungazinzi
- Isicaphucaphu, ukuhlanza, urhudo
- Abafundi abavulelekileyo
- Ukungcangcazela, ukushukuma kwemisipha, ukuqina
- Ukubila okugqithisileyo, ukubanda, kunye nokungcangcazela
- Ukudideka okukhulu, ukulahlekelwa zingqondo
- Ukwanda kwesantya sentliziyo, ukunyuka koxinzelelo lwegazi
- Umkhuhlane, ukuxhuzula, ukulahlekelwa zingqondo
Lumka ngeengcinga zokuzibulala.
Oku kubaluleke kakhulu. Umngcipheko weengcinga zokuzibulala unokwanda kancinci kwiiveki zokuqala zokuqala zokusebenzisa amayeza okudakumba okanye xa kutshintshwa umthamo, ingakumbi kubantu abancinci nakubantwana abangaphantsi kweminyaka engama-24 ubudala. Qaphela kakhulu ezi mpawu zilandelayo.
- Ukudandatheka kuya kusiba mandundu.
- Ukucinga ngokuphelisa ubomi bakho.
- Uhlaselo loloyiko.
- Ukungalali.
- Ukungazoli, ubundlobongela, ukucaphuka.
- Ukwenza izinto ngaphandle kokucinga nokuvuya ngendlela engaqhelekanga.
Ukuba wena okanye umntwana wakho nifumana naziphi na kwezi mpawu, thethani nogqirha wakho ngokukhawuleza .
Ngaba unokuba likhoboka lale mithi?
Hayi. Ezi azithathwa njengeziyobisi ezibangela umlutha njengeziyobisi ezibangela umlutha. Nangona kunjalo, kukho ingxaki.Ukuba ngequbuliso uyeka ukusebenzisa eli yeza kangangeeveki ezingaphezu kwezi-6, unokufumana ukungakhululeki emzimbeni. Oku kubizwa ngokuba yi-'antidepressant discontinuation syndrome'. Iimpawu ezinje ngokutshintshatshintsha kweemvakalelo, isiyezi, kunye noxinzelelo zinokubakho.
Ngoko ke, ungaze, nangasiphi na isizathu, uyeke ukuthatha eli yeza ngequbuliso ngaphandle kokubonisana nogqirha wakho. Ukuyeka kufuneka kwenziwe phantsi kwengcebiso kagqirha wakho, ngokunciphisa kancinci kancinci umthamo.
Ezinye iindlela zokusebenzisa iCelexa kunye neLexapro (Indlela zokusebenzisa ezingafakwanga kwileyibhile)
"Ukusetyenziswa ngaphandle kweleyibhile" kubhekisa ekunikeni iyeza kwimeko engavunywanga ngokusemthethweni kuloo meko, kodwa oogqirha bayazi ngamava ukuba eli yeza liluncedo kuloo meko. Omabini la mayeza asetyenziselwa ezinye iimeko ezininzi, kuquka:
- Ezinye iimeko apho iCitalopram (Celexa) ingasetyenziswa khona:
- Ingxaki Yokuxhalaba Okugqithisileyo (OCD)
- Ingxaki yoXinzelelo
- Ingxaki Yokukhathazeka Kwentlalo
- Ingxaki yoxinzelelo emva kwengozi (PTSD)
- Ukuphuma komchamo ngaphambi kwexesha
- Ezinye iimeko apho i-Escitalopram (Lexapro) ingasetyenziswa khona:
- Ingxaki Yokukhathazeka Kwentlalo
- Isifo sokungakhathali (OCD)
- Ingxaki yoXinzelelo
- Iimpawu ezinxulumene nokuya exesheni (umz. ubushushu obuphezulu)
Ngoko ke, yeyiphi onokuyikhetha phakathi kwezi zimbini?
Lo ngumbuzo obaluleke kakhulu. Esi sisigqibo ugqirha wakho aza kusenza emva kokukuxilonga nokuqwalasela izinto ezininzi, ezifana neempawu zakho, ubudala, kunye nezinye iimeko zempilo.
- Ukuba unexhala kwaye uxinezelekile, iLexapro inokuba lolona khetho lungcono.
- Ukuba unembali yesifo sentliziyo, iLexapro inokuba lolona khetho lungcono kuba ineengozi ezincinci.
- Kwabanye abantu, i-'Celexa' isebenza kakuhle. Kwabanye, i-'Lexapro' ifanelekile ngakumbi.
Kungoko ke, kungcono ukuthetha ngokukhululekileyo nogqirha wakho ngale nto. Musa ukwenza izigqibo ngokusekelwe koko ukufundileyo kwi-intanethi. Ugqirha wakho uza kukhetha elona yeza lifanelekileyo nelikhuselekileyo kuwe.
Umyalezo Wokuya Ekhaya
- I-Celexa (Citalopram) kunye ne-Lexapro (Escitalopram) ngamayeza e-SSRI anyanga ukudakumba kunye nokuxhalaba ngokulinganisela amanqanaba e-serotonin engqondweni.
- ILexapro yinguqulelo ephucukileyo nejolise ngakumbi yeCelexa, ngoko ke kukho umahluko omncinci kwindlela esetyenziswa ngayo kunye nezinye iziphumo ebezingalindelekanga.
- Kubaluleke kakhulu ukuba uqaphele iingcinga zokuzibulala xa usebenzisa eli yeza, ingakumbi kwabo bangaphantsi kweminyaka engama-24 ubudala. Ukuba ubona naluphi na utshintsho, xelela ugqirha wakho ngoko nangoko.
- Qaphela iimpawu zesifo esibi esibizwa ngokuba yi-'Serotonin Syndrome'. Ukuba ufumana iimpawu ezinjalo, yiya esibhedlele ngokukhawuleza.
- Ungaze uyeke ukuthatha eli yeza ngequbuliso ngaphandle kwengcebiso kagqirha. Ukwenza njalo kunokubangela ukungakhululeki emzimbeni.
- Xelela ugqirha wakho ngazo zonke ezinye iziyobisi, iivithamini, kunye neemeko zempilo ozisebenzisayo.
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