Siyazi ukuba iSickle Cell Disease ayisiyonto ilula ukujongana nayo. Ungacinga ukuba kunzima kangakanani ukuphila neentlungu kunye neengxaki ezibangelwa sesi sifo. Ngoko ke, indlela ekuphela kwayo yokunyanga esi sifo ngokupheleleyo kukufakelwa umongo wethambo. Kodwa oku akuyonto inokwenziwa ngaxeshanye. Ukuba ucinga ngokufakelwa okunjalo wena okanye umntwana wakho, masithethe ngako ngokweenkcukacha ezithe vetshe, ngokulula.
Kwenzeka ntoni kanye kanye ngale nto?
Ngamafutshane, ukufakelwa komongo wethambo kubandakanya ukususa iiseli ze-stem zomzimba wakho ezenza iiseli zegazi ezibomvu, ezibizwa ngokuba ziiseli ze-hematopoietic stem, uze uzifake endaweni yazo iiseli ze-stem eziphilileyo. Cinga ngako njengokususa abasebenzi abaneziphene kumzi-mveliso wokwenza igazi emzimbeni wakho uze ubafake endaweni yabo abasebenzi abaphilileyo abasebenza kakuhle. Emva koku, umzimba wakho uyayeka ukwenza iiseli ezimile okwesikele ezibangela isifo.
Kule nkqubo, oogqirha bafaka iiseli ze-stem eziphilileyo ezivela kumntu ophilileyo ngetyhubhu ye-IV, ngokuqhelekileyo njengesisombululo se-saline esifakwa emthanjeni osengalweni yakho. Xa sele zisemzimbeni wakho, ezi seli zihamba ngqo ziye kumongo wakho wethambo, apho zihlala khona zize ziqale ukwenza iiseli zegazi eziphilileyo.
Nangona oku kusenokuvakala kulula, ukufakelwa umongo wethambo yinkqubo ende neyinkimbinkimbi efuna unonophelo olukhulu nengqalelo. Ifuna iinyanga zokulungiselela kunye nokulandelelana.
Indlela eyenzeka ngayo le nkqubo inkulu
Emva kokufumana umntu oza kukunika uncedo, kuya kufuneka uhlale esibhedlele iiveki ezimbalwa. Emva koko, oogqirha baza kukujonga iinyanga. Makhe sibone ukuba oku kusebenza njani inyathelo ngenyathelo.
| Inyathelo / Ubude | Inkcazo yoko kwenzekayo |
|---|---|
| Inyathelo 1: Ukulungiselela ngaphambi kokufakelwa (iiveki ezi-1-2) | Uza kungeniswa esibhedlele kwiiveki ezimbini ngaphambi kokufakelwa isibeleko. Apha uza kufumana i-chemotherapy.Unyango luyanikwa. La mayeza anamandla atshabalalisa iiseli zomongo emzimbeni wakho ezenza ezo seli zegazi ezineziphene. Akwawenza buthathaka amajoni akho omzimba. Akwenza oku ukuze ayeke ukuhlasela nokungawamkeli amaseli asandul’ ukufakelwa. Ngamanye amaxesha unyango lwemitha lunokunikwa. |
| Inyathelo lesi-2: Yenza utyando (ngosuku olunye) | Emva koko, oogqirha bafaka iiseli eziphilileyo ezivela kumxhasi emzimbeni wakho nge-IV. Ezi seli ziya kuthatha indawo yomongo omdala wethambo kwaye ziqale ukwenza igazi eliphilileyo. |
| Inyathelo lesi-3: Ukubuyela kwimeko yesiqhelo emva kokufakelwa isithombo (inyanga e-1 ukuya kwiinyanga ezi-6-12) | Kuya kufuneka uhlale esibhedlele kangangenyanga emva kokufakelwa isibeleko. Ngeli xesha, iqela lezonyango liza kwenza uvavanyo rhoqo ukuqinisekisa ukuba iiseli ezintsha zisebenza kakuhle. Nje ukuba kuqinisekiswe ukuba ukufakelwa isibeleko kube yimpumelelo kwaye iiseli ezintsha zizinzile, uya kukwazi ukuphuma esibhedlele. Nangona kunjalo, kungathatha iinyanga ezi-6 ukuya kwezi-12 okanye ngaphezulu ukuba iiseli zakho zegazi kunye nenkqubo yomzimba yokuzikhusela ziphinde ziphile ngokupheleleyo. Ngeli xesha, ugqirha wakho uya kujonga impilo yakho ngokusondeleyo. |
Ungamfumana njani umnikeli ofanelekileyo?
Abantu abafanelekileyo ukufakelwa umongo wethambo badla ngokuba ngabo baye baba neengxaki ezinzima okanye baneentlungu eziqatha ngenxa yesifo se-sickle cell. Ugqirha wakho uya kuqala aqinisekise ukuba uphilile ngokwaneleyo ukuba ungatyandwa. Kuya kufuneka uthethe nogqirha wengqondo okanye unontlalontle ukuqinisekisa ukuba ulungele ngokwengqondo le nkqubo inde.
Enye yezona ngxaki zinkulu kule nkqubo kukufumana umntu oza kufana ngqo nomongo wakho wethambo.
- Abantakwenu: Uvavanyo lwegazi lunokubonisa ukuba umongo womntakwenu, udadewenu, okanye umzali wakho uyahambelana na. Phakathi kwama-20% nama-30% abantwana abafuna ukufakelwa utyando banomntakwabo okanye udadewenu onomongo womongo ofanayo.
- IiRejista zeSizwe: Kukho iirejista zesizwe zabantu abaye bazinikela ngokuzithandela ekunikeleni ngethambo lomongo. Ungazama ukufumana umntu ofanelekileyo ngazo.
- Igazi leNtambo yoMbilical: Ukuba unegazi lentambo eligciniweyo emva kokuba umntwana wakho ezelwe, iiseli ze-stem ezikuyo nazo zingasetyenziselwa le njongo.
Zithini iingozi zoku?
Njengalo naluphi na utyando olukhulu, ukufakelwa umongo wethambo kuneengozi ezithile kunye neengxaki. Kubalulekile ukuzazi ezi zinto kwangaphambili.
| Umngcipheko | Inkcazo kunye noko kufuneka ukwazi |
|---|---|
| Ukwaliwa | Oku kubizwa ngokuba yiGraft-versus-Host Disease (GVHD) . Oku kuthetha ukuba iiseli ezisempilweni ezisandula ukufakelwa ziqala ukuhlasela amalungu akho omzimba. Le meko inokuchaphazela umntu omnye kwabalishumi. Kukho amayeza okuyilawula, kodwa ngamanye amaxesha ukuba amayeza awasebenzi, inokukhokelela ekonakaleni kwamalungu omzimba kwanokufa. |
| Iintsholongwane | Ngenxa yokuba i-chemotherapy enikwa ngaphambi kokufakelwa iyenza buthathaka inkqubo yomzimba yokuzikhusela, unokufumana lula usulelo oluvela kwiibhaktheriya kunye neentsholongwane. Ugqirha wakho uza kukunika amayeza okuthintela oku. |
| Iingxaki zesondlo | Unyango lwe-chemotherapy lunokubangela iziphumo ebezingalindelekanga ezifana nokulahlekelwa ngumdla wokutya, ukuhlanza, kunye norhudo, nto leyo enokubangela iingxaki zesondlo. |
| Umonakalo wesibindi | Imithambo yegazi esibindini inokonakala. Oku kubizwa ngokuba yi-Veno-occlusive Disease . Malunga nomntu omnye kwabangamashumi amabini unokuhlangabezana nalo monakalo mkhulu. |
| Ukungazali | Amaxesha amaninzi, amayeza anikwayo ngaphambi kokufakelwa inzala anokubangela ukuba umntu angafumani bantwana. Le yingxaki ebucayi, ngoko ke thetha nogqirha wakho kwangaphambili kwaye uqaphele ukhetho onalo. |
Kuthekani ukuba ukufakelwa isitho akuphumeleli?
Ngenxa yazo zonke ezi zinto, kufuneka sithembe ukuba izinto ziza kuhamba kakuhle. Kubantu abalithoba kwabalishumi , ukufakelwa kwesisu kuyaphumelela, iiseli zegazi ezisempilweni ziqala ukwakheka, kwaye isifo se-sickle cell siyanyangeka ngokupheleleyo. Ezo ziindaba ezilungileyo.
Nangona kunjalo, kwiimeko ezingaqhelekanga, ukuba ukufakelwa isibeleko akuphumeleli, oogqirha banokuphinda le nkqubo. Okanye banokuphinda bafake ii-stem cells zakho ezindala emzimbeni wakho. Ukuba oko kuyenzeka, isifo se-sickle cell siya kubuya.
Umyalezo Wokuya Ekhaya
- Eyona ndlela yokunyanga ngokupheleleyo isifo se-sickle cell kukufakelwa umongo wethambo.
- Le yinkqubo enzima equka i-chemotherapy, ukulaliswa esibhedlele ixesha elide, kunye neenyanga zokuchacha.
- Eyona ngxaki inkulu kule nkqubo kukufumana umnikeli ofanelekileyo kuwe.
- Kukho iingozi ezinkulu ezinxulumene nale nkqubo, ezifana ne-GVHD, usulelo, kunye nokulahlekelwa ngamandla okuba nabantwana. Kodwa uninzi lokufakelwa izitho luphumelela.
- Kubalulekile ukuxoxa ngazo zonke izinto ezilungileyo nezingalunganga ngokunzulu nangokukhululekileyo nogqirha wakho ngaphambi kokuba ugqibe ekubeni olu lolona khetho lufanelekileyo na kuwe okanye kumntwana wakho.
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