Uxinzelelo lwegazi oluphezulu, okanye njengoko sonke sisazi, "uxinzelelo," yingxaki yempilo abantu abaninzi kwilizwe lethu abajongene nayo namhlanje. Ungakhumbula ukuba xa usiya kugqirha, bakunika iintlobo ezahlukeneyo zamayeza oxinzelelo lwegazi. Namhlanje, siza kuthetha ngenye yezona ntlobo zamayeza zisetyenziswa kakhulu nezibalulekileyo. Leyo yi-calcium channel blocker.
Ngamafutshane, yintoni le Calcium Channel Blocker?
Ngamafutshane, la ngamayeza anceda ekulawuleni okanye ekunciphiseni uxinzelelo lwegazi. Asebenza ngokunciphisa ukungena kweminerali ebizwa ngokuba yicalcium kwiiseli zentliziyo yethu kunye nemithambo yegazi.
Ngoku mhlawumbi ucinga, "I-calcium ilungile emzimbeni, kutheni uyeka ukuyisebenzisa?" Ibali lihamba ngolu hlobo. I-calcium ibalulekile kwimisipha esentliziyweni yethu nakwimithambo yegazi ukuze inciphe, oko kukuthi, iqine. Xa imithambo yegazi iqina, uxinzelelo lwegazi, oko kukuthi, uxinzelelo, luyanda. Ngoko ke eli yeza lenza ukunciphisa inani le-calcium eliya kwezo seli. Emva koko imisipha esezindongeni zemithambo yegazi iyaphumla kancinci, njengaxa ukhulula into ebiqinile. Xa imithambo yegazi iphumla, igazi linokugeleza lula, kwaye uxinzelelo lwegazi luyehla . Uyaqonda? Leyo yinkqubo esisiseko yale yeza.
Zeziphi iimeko ezisetyenziswa leli yeza?
Izithinteli zeCalcium channel ngamayeza anikwa ngoogqirha ikakhulu kwiingxaki ezininzi zentliziyo nemithambo yegazi. Ngamanye amaxesha asetyenziswa nakwezinye iimeko, nangona engavunywanga ngokusemthethweni, ngokwamava oogqirha. Makhe sijonge ukuba zeziphi.
| Ukusetyenziswa | Imeko yezonyango |
|---|---|
| Izihlandlo ezisetyenziswa kakhulu |
|
| Ukusetyenziswa okungekho kwileyibhile |
|
Ngaba kukho iintlobo eziphambili ze-calcium channel blockers?
Ewe, kukho iintlobo ezimbini eziphambili. La mayeza ahlulwe ngokwendlela asebenza ngayo umahluko omncinci. Amayeza anikwe ngugqirha wakho asenokuba ngomnye wawo.
1. IiDihydropyridines (DHP)
2. Ii-non-dihydropyridines (ezingezizo ii-DHP)
Yintoni umahluko phakathi kwezi ntlobo zimbini?
Ngamafutshane, uhlobo olubizwa ngokuba yi-DHP lujolise kakhulu kwimithambo yegazi . Oko kuthetha ukuba luchaphazela kuphela imithambo yegazi. Ke ngoko, olu hlobo lusebenza kakhulu ekunyangeni uxinzelelo lwegazi oluphezulu, oko kukuthi, uxinzelelo.
Uhlobo olungelulo lwe-DHP luchaphazela imithambo yegazi kunye nemisipha yentliziyo . Ngoko ke, olu hlobo lukwanceda ekulawuleni izinto ezifana nesantya sentliziyo kunye nesingqisho. Ezi zihlala zinikwa iimeko ezifana nokubetha kwentliziyo okungahambelaniyo (arrhythmias).
Ngoku makhe sibone ukuba zeziphi amayeza asetyenziswa kakhulu kwezi ndidi. Jonga ukuba igama lamayeza owasebenzisayo likuluhlu.
| Uhlobo lweyeza | Imizekelo (amagama amayeza) |
|---|---|
| I-Dihydropyridine (DHP) (Isebenza kakhulu kwimithambo yegazi) |
|
| I-Non-dihydropyridine (engeyiyo i-DHP) (Isebenza kwimithambo yegazi kunye nentliziyo) |
|
Kufuneka ndithathe eli yeza ixesha elingakanani?
Oku kuxhomekeke kakhulu kwimeko yakho yempilo.
Khawuthelekelele ukuba une-high blood pressure. Ukuba uzilolonga rhoqo, ulawula ukutya kwakho, wehlisa umzimba, kwaye uphila ubomi obusempilweni, unokukwazi ukulawula uxinzelelo lwakho lwegazi ngaphandle kwamayeza. Ukuba kunjalo, unokukwazi ukuthetha nogqirha wakho kwaye, ngokusekelwe kwingcebiso yakhe, unciphise okanye uyeke amayeza.
Kodwa khumbula into enye: Ungaze uyeke ukuthatha eli yeza ngequbuliso ngaphandle kwengcebiso kagqirha wakho. Ukwenza njalo kunokubangela ukuba uxinzelelo lwakho lwegazi lunyuke ngequbuliso, nto leyo enokuba yingozi.
Kodwa ukuba unemeko ehlala ixesha elide efana nokubetha kwentliziyo okungaqhelekanga (i-arrhythmia), kunokufuneka uthabathe la mayeza ubomi bakho bonke. La mayeza ngokubanzi akhuselekile ukuwasebenzisa ixesha elide.
Zithini iingenelo kunye neziphumo ebezingalindelekanga zale mithi?
Njengayo nayiphi na imithi, ii-calcium channel blockers zinokuba neenzuzo kunye nemiphumo emibi emincinci.
Masiqale sithethe ngeenzuzo:
- Isebenza kakuhle kakhulu: Eli yeza lisebenza ngempumelelo kubantu bayo nayiphi na iminyaka. Linokunyanga uxinzelelo lwegazi kunye nezinye iingxaki ezinxulumene nalo.
- Unyango Olujoliswe Kulo: Ugqirha wakho unokukhetha iyeza (i-DHP okanye elingelona i-DHP) elifanele imeko yakho.
- Inganikwa kunye namanye amayeza: Ngamanye amaxesha eli yeza lidityaniswa namanye amayeza, afana namayeza okwehlisa i-cholesterol, kwaye liza lipilisi enye. Ngale ndlela, kulula ukulisela eli yeza.
Ngoku makhe sijonge iziphumo ebezingalindelekanga ezinokubakho:
Ayingabo bonke abantu abafumana iziphumo ebezingalindelekanga. Abanye abantu banokufumana iziphumo ebezingalindelekanga ezincinci. Ezi ziphumo bezingalindelekanga zahlukile kancinci kwiintlobo ezimbini ze-DHP kunye ne-non-DHP esizixubushileyo ngaphambili.
| Uhlobo lweyeza | Iziphumo ebezingalindelekanga eziqhelekileyo |
|---|---|
| Uhlobo lwe-DHP (umz. i-Amlodipine, i-Nifedipine) |
|
| uhlobo olungelulo olwe-DHP (umz. iDiltiazem, iVerapamil) |
|
Ukongeza, ezinye izinto ezithintela i-calcium channel zinokubangela ukuba iintsini zikhule zijikeleze amazinyo ngokungeyomfuneko . Kwakhona, ukuba une-gastritis (GERD), iimpawu ezifana ne-heartburn zinokwanda.
Ufanele ufune nini ingcebiso yezonyango ngokukhawuleza?
Kubaluleke kakhulu ukuxelela ugqirha wakho ukuba kukho naziphi na iimpawu ezintsha ozifumanayo ngelixa usebenzisa eli yeza, ingakumbi ukuba zinxulumene nentliziyo yakho. Nangona kunjalo, ukuba ufumana naziphi na kwezi mpawu zilandelayo, yiya kwigumbi longxamiseko esibhedlele (ETU) ngokukhawuleza.
- Ubunzima bokuphefumla
- Intlungu ebuhlungu esifubeni
- Ukubetha kwentliziyo okungaqhelekanga (i-arrhythmia) okanye i-palpitations
- Ukuquleka
- Isiyezi rhoqo
Kwakhona, ukuba ufumana naziphi na iimpawu zempendulo yokunganyamezelani komzimba, njengokurhawuzelela kwesikhumba, ukurhawuzelela, okanye ukudumba kobuso okanye amalungu omzimba, funa ingcebiso kagqirha ngokukhawuleza.
Yintoni omawuyenze ukuba uphoswe yidosi yeyeza?
Lo ngumbuzo abantu abaninzi abawubuzayo. Ukuba ngequbuliso ulibele ukuthatha idosi, musa ukuthatha iipilisi ezimbini ngaxeshanye nangasiphi na isizathu. Ukuba "ufikelela" kwidosi, ungenza ukugqithisa kwaye ubangele iimeko eziyingozi, ezifana nesantya sentliziyo esiphantsi kakhulu.
Ngokwesiqhelo, kufuneka uthathe idosi ephosiweyo ngokukhawuleza nje ukuba ukhumbule uze uthathe idosi elandelayo ngexesha elicwangcisiweyo. Nangona kunjalo, ukuba idosi yakho elandelayo ifika kungekudala, yitsibe idosi ephosiweyo uze uthathe idosi elandelayo ngexesha elicwangcisiweyo. Ukuba awuqinisekanga, cela ingcebiso kugqirha wakho.
Ngaba kukho abantu abangafanelanga basebenzise eli yeza?
Ewe. La mayeza awafanelekanga kubantu abaneengxaki ezithile zempilo. Ngaphambi kokuba uqale ukusebenzisa la mayeza , qiniseka ukuba wazise ugqirha wakho ukuba unayo nayiphi na kwezi meko zilandelayo:
- Ukuba unesifo sentliziyo
- Ukuba uxinzelelo lwegazi luphantsi kakhulu
- Ukuba ukhulelwe okanye unethemba lokukhulelwa
- Ukuba uneengxaki zesibindi
- Ukuba uneentlobo ezithile zeengxaki zesingqisho sentliziyo
Ngaba kukho iingxaki ngamanye amayeza nokutya?
Ii-calcium channel blockers ziluhlobo lwamayeza anokusebenzisana namanye amayeza amaninzi. Kufuneka ulumke kakhulu xa uwasebenzisa kunye namanye amayeza anciphisa uxinzelelo lwegazi okanye achaphazela izinga lokubetha kwentliziyo.
Kwakhona, into abantu abaninzi abangayiqondiyo kukuba ijusi yegrapefruit okanye ijusi yegrapefruit ayilunganga kweli yeza. Ikhemikhali ekwigrapefruit inokutshintsha indlela amayeza afunxwa ngayo ngumzimba, nto leyo enokunyusa uxinano lwamayeza ngokungeyomfuneko. Ke ngoko, kungcono ukuhlala kude negrapefruit ngelixa usela eli yeza.
Kubaluleke kakhulu ukwazisa ugqirha wakho malunga namanye amayeza, iivithamini, okanye amayeza esintu owasebenzisayo.
Umyalezo Wokuya Ekhaya
- Ii-calcium channel blockers luhlobo olusebenzayo kakhulu lwamayeza asetyenziswa rhoqo kwi-high blood pressure kunye nesifo sentliziyo.
- Kubaluleke kakhulu ukusela amayeza akho ngedosi nangexesha elifanelekileyo njengoko ugqirha wakho ekuyalele.
- Musa ukuyeka ukuthatha amayeza ngequbuliso nangasiphi na isizathu ngaphandle kwengcebiso kagqirha.
- Khumbula ukuba iziphumo ebezingalindelekanga ezifana nokudumba kweenyawo, intloko ebuhlungu, kunye nesiyezi zinokubakho. Ukuba ufumana naluphi na uvakalelo olungathandekiyo, yazisa ugqirha wakho.
- Ukuba ufumana iimpawu ezinzima ezifana nobunzima bokuphefumla, iintlungu zesifuba, okanye ukuquleka, yiya kwiSebe lezeMpilo eziNgxamisekileyo (ETU) esibhedlele ngoko nangoko.
- Xelela ugqirha wakho ngazo zonke ezinye iziyobisi ozisebenzisayo. Kwakhona, kuphephe ukutya okanye ukusela i-grapefruit ngelixa usebenzisa eli yeza.
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