Ngaba wena okanye umntwana wakho nisoloko ninxaniwe? Kwaye ngaba nihlala nichama rhoqo? Mhlawumbi umntwana wakho umanzisa ibhedi ebusuku. Kwimeko ezinjalo, ugqirha wakho unokukunika ipilisi ebizwa ngokuba yi-'Desmopressin'. Ekubeni eli yeza lisetyenziswa rhoqo, kwaye kuba kufuneka ulumke kakhulu xa ulisebenzisa, namhlanje siza kuthetha ngale pilisi yeDesmopressin ngokulula.
Yintoni iDesmopressin?
Ngamafutshane, iDesmopressin yihomoni yokwenziwa eyenziwe kwilebhu efana nehomoni ethi 'Vasopressin' eveliswa ngumzimba wethu ngokwendalo. Ihomoni ethi Vasopressin emzimbeni wethu ithumela umyalezo ovela engqondweni ukuya kwizintso, ilawula ubungakanani bamanzi akhutshwa emzimbeni njengomchamo. Ngoko ke, le pilisi yeDesmopressin yenza into efanayo.
Umsebenzi wayo ophambili kukulawula ubungakanani bomchamo okhutshwa zizintso. Oko kukuthi, kunciphisa ukulahleka kwamanzi ngokungeyomfuneko emzimbeni kwaye kunceda ukugcina ulungelelwano lwamanzi emzimbeni. ESri Lanka, ungalibona eli yeza phantsi kwegama lophawu iDDAVP.
Zithini iindlela ezisetyenziswa ngayo eli yeza?
Oogqirha ikakhulu banika eli yeza kwiimeko ezahlukeneyo.
- I-Central Diabetes Insipidus: Le yimeko apho ingqondo ivelisa i-hormone encinci yeVasopressin. Ngenxa yoko, kukho ukuchama kakhulu kunye nokunxanwa kakhulu. I-Desmopressin iluncedo kakhulu ekulawuleni le meko.
- Ukuchama ebhedini/I-Enuresis yasebusuku: Oogqirha bacebisa eli yeza kule ngxaki, ingakumbi kubantwana abaneminyaka engaphezu kwemi-4 ubudala. Linceda ekunciphiseni umchamo oveliswa ebusuku kwaye lithintele umntwana ekuchameni ebhedini.
- Emva kokwenzakala entloko okanye utyando: Emva kokwenzakala entloko kakhulu okanye utyando oluthile lobuchopho, umsebenzi wehomoni i-vasopressin unokuphazamiseka okwethutyana. Ikwasetyenziselwa ukulawula ukuchama kakhulu ngamaxesha anjalo.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uthathe amayeza
Ngaphambi kokuba unike iDesmopressin, kubaluleke kakhulu ukwazisa ugqirha wakho ngembali yakho epheleleyo yempilo, ingakumbi ukuba unayo nayiphi na kwezi meko.
- Ukuba ukhe waba nehlwili legazi ngaphambili
- Ukuba unesifo esifana ne-Cystic Fibrosis
- Ukuba unesifo sentliziyo okanye uxinzelelo lwegazi oluphezulu
- Ukuba unayo nayiphi na uhlobo lwesifo sezintso
- Ukuba sele ufunyenwe unezinga eliphantsi le-sodium egazini (oku kubaluleke kakhulu)
- Ukuba une-allergy kwiDesmopressin, iVasopressin okanye naluphi na olunye unyango, ukutya, okanye idayi
- Ukuba ukhulelwe okanye uzama ukukhulelwa
- Ukuba umama uncancisa umntwana wakhe
Ngokusekelwe kolu lwazi, ugqirha uya kugqiba ukuba eli yeza lifanelekile kuwe okanye akunjalo kunye nomlinganiselo oza kunikwa.
Ndingayisebenzisa njani kanye kanye le yeza?
Kubaluleke kakhulu ukwazi kakuhle indlela yokusebenzisa eli yeza.
- Le pilisi kufuneka ithathwe neglasi yamanzi.
- Kubaluleke kakhulu ukusela amayeza akho njengoko ugqirha wakho ekuyalele. Ukuba uwasela kube kanye ngemini, uwasele ngexesha elifanayo yonke imihla (ngesiqhelo ngaphambi kokuba ulale ebusuku).
- Ungaze usele ngaphezu kokuba ugqirha ekuxelele.
- Xa kunikwa abantwana eli yeza: Xa kunikwa abantwana eli yeza, imiyalelo kagqirha wezifo zabantwana kufuneka ilandelwe ngokuchanekileyo.
- Ukuba ngempazamo uthabathe kakhulu: Ukuba ucinga ukuba ngempazamo uthabathe kakhulu eli yeza, qhagamshelana neZiko loLwazi lweePoison kwiSibhedlele sikaZwelonke saseColombo ngoko nangoko. Okanye yiya kwiSebe leNgxamiseko (ETU) lesibhedlele esikufutshane.
Eli yeza limiselwe wena wedwa. Musa ukulinika omnye umntu, nokuba uneempawu ezifanayo nezakho. Lisenokuba yingozi.
Yintoni omawuyenze ukuba uphoswe yidosi yeyeza?
Ukuba ulibele ukuthatha idosi, yithathe kwangoko xa ukhumbula. Kodwa ukuba sele kuza kufuneka uthathe idosi elandelayo, yitsibe idosi oyiphosileyo uze uthathe idosi elandelayo ngexesha elicwangcisiweyo. Ungaze uthathe idosi ephindwe kabini.
Izinto ekufuneka uzilumkele ngakumbi xa usebenzisa amayeza
Le yeyona nxalenye ibalulekileyo. Kufuneka uqaphele kakhulu ezinye iinkalo zendlela ophila ngayo xa usebenzisa eli yeza.
Ukungenisa ulwelo - Ingqalelo Ephambili!
Le yeyona nto ibalulekileyo . I-Desmopressin ibangela ukugcinwa kwamanzi emzimbeni, ngoko ke kufuneka uqaphele kakhulu malunga nokuba usela amanzi angakanani.
Oogqirha badla ngokucebisa bathi, "Cima unxano ngamanzi." Lususe, susa, susaHlamba, hlamba Yisuse, susa Yisuse, susaPhumla, thatha Yisuse, susa Yisuse, susa Yilahle, fumana Yilahle, fumanaPhumla, phumla Yisuse, susa Yisuse, susaYilahle, yilahle, yilahle, yilahleYilahle, yithi "Thula, valaUkusela amanzi amaninzi okanye amancinci kakhulu kunokuba yingozi. Ngenxa yokuba eli yeza libangela ukuba umzimba wakho ugcine amanzi, ukuba usela amanzi amaninzi, amanqanaba e-sodium egazini lakho anokuba sezantsi ngendlela eyingozi.
Izifo
Ukuba uziva uphazamisekile esiswini, uhlanza, okanye urhudo, okanye ukuba unesifo somkhuhlane kunye nosulelo, yeka ukuthatha eli yeza ngoko nangoko kwaye udibane nogqirha wakho. Oku kungenxa yokuba amanzi amaninzi anokulahleka emzimbeni ngeli xesha, kwaye ukuqhubeka nokusebenzisa eli yeza kunokubangela utshintsho olukhulu kumanqanaba e-sodium.
Iziphumo ebezingalindelekanga ezinokubakho ngenxa yale yeza
Njengayo nayiphi na imithi, iDesmopressin inokuba nemiphumo emibi. Eminye incinci, kodwa eminye ifuna ingqalelo ekhethekileyo.
| Imiphumela | Inkcazo kunye nento omawuyenze |
|---|---|
| Iziphumo ebezingalindelekanga ekufuneka zixelwe kugqirha wakho ngoko nangoko | |
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe okanye ulwimi. Funa ingcebiso kagqirha ngokukhawuleza. |
| Iimpawu zezinga eliphantsi le-sodium emzimbeni | Intloko ebuhlungu kakhulu, ukozela, isiyezi, ukudideka, isicaphucaphu, ukuhlanza, ukuxhuzula kwemisipha, ukungazinzi, okanye ukuxhuzula. Le yimeko engxamisekileyo. Yiya kwi-ETU ngoko nangoko. |
| Ukunyuka kwesisindo ngequbuliso okanye ukudumba | Ukudumba emilenzeni okanye emaqatheni, ukunyuka kobunzima ngequbuliso. Olu luphawu lokugcinwa kwamanzi emzimbeni. |
| Ubunzima bokuphefumla | Ubunzima bokuphefumla, iintlungu zesifuba okanye ukuqina. |
| Utshintsho kwisantya sentliziyo | Ukubetha kwentliziyo ngokukhawuleza okanye ngokungangqalanga. |
| Izinto omele uzixelele ugqirha wakho ukuba ziyaqhubeka okanye ziyakukhathaza | |
| Intloko ebuhlungu | Intloko ebuhlungu kancinci ingenzeka. |
| Umlomo owomileyo | Ukuziva umlomo owomileyo. |
| Isicaphucaphu esincinci | Ukungakhululeki esiswini okanye isicaphucaphu. |
Ugcina njani amayeza ekhuselekile?
- Qiniseka ukuba uyigcina kude nabantwana .
- Gcina kubushushu begumbi (phakathi kwama-20-25 degrees Celsius). Khusela kubushushu obugqithisileyo kunye nelanga elithe ngqo.
- Lahla amayeza aphelelwe lixesha ngaphandle kokuwasebenzisa.
Umyalezo Wokuya Ekhaya
- I-Desmopressin liyeza elilawula ubungakanani bomchamo oveliswa zizintso kwaye kufuneka lisetyenziswe kuphela emva kwengcebiso kagqirha.
- Lumka kakhulu malunga nobungakanani bamanzi oselayo ngelixa usela eli yeza. Musa ukusela amanzi amaninzi okanye amancinci kunokuba ugqirha wakho ekuxelela.
- Ukuba ufumana iimpawu ezifana nentloko ebuhlungu kakhulu, isiyezi, ukudideka, okanye ukuhlanza, oko kungaba luphawu oluyingozi lokuba namanqanaba aphantsi esodium egazini. Yiya kugqirha ngoko nangoko.
- Yeka ukusebenzisa amayeza uze udibane nogqirha wakho ukuba ufumana ukuhlanza, isisu esibuhlungu, okanye umkhuhlane.
- Eli yeza lelakho kuphela. Musa ukwabelana ngalo nabanye abantu nangasiphi na isizathu.
👩🏽⚕️ Imibuzo eyongezelelweyo (Ii-FAQ)
💬 Zisetyenziselwa ntoni iipilisi zeDesmopressin / DDAVP?
Eli liyeza elisebenzayo kakhulu ekuthinteleni 'isifo seswekile insipidus' kunye 'nokuchama ebhedini' ebantwaneni! Lifaka ihomoni yendalo (ADH) eveliswa yingqondo yethu emzimbeni, kwaye liphinde lifunxe amanzi akhutshwa njengomchamo.
💬 Ungayekisa njani ukungachami/ukuchama ebhedini ngale hormone yokwenziwa (iDesmopressin)?
Ngokwesiqhelo, ingqondo ithumela imiyalelo kwizintso zethu yokuba 'zigcine amanzi emzimbeni' ngehomoni ethi 'ADH'! Iingqondo zabanye abantu azivelisi oku. Xa eli yeza (ipilisi/isitshizi) lingena emzimbeni, liya ngqo kwizintso (ii-V2 receptors kwizintso) kwaye livale zonke iingcango ezivumela amanzi ukuba angene, njengokucima impompo, ukuthintela ukuveliswa komchamo nge-100%.
💬 Yeyiphi ingozi eyingozi (iBlack Box Warning) enokwenzeka xa uthatha ipilisi (iDesmopressin) ethintela ukuveliswa komchamo?
Eyona ngozi inkulu yoku 'yiHyponatremia / Ukunxila ngamanzi'! Ekubeni ungachami, ukuba usela amanzi/ulwelo oluninzi emva kokusela le pilisi, onke loo manzi aya kuzalisa umzimba wakho kwaye i-100% yetyuwa egazini lakho iya kunyibilika. Ukuba ityuwa iyawa, isigulana sinokuxhuzula ngequbuliso size sife! (Ke ngoko, musa ukusela oku ukuba unxanelwe amanzi kakhulu).
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