Ngaba ugqirha wakho ukuxelele ukuba unesifo seswekile, okanye ukuba sele ukufutshane nokukhula kwesifo seswekile (prediabetes)? Xa usitsho, kusenokwenzeka ukuba ukhe weva igama elithi "insulin resistance". Usenokuba uyazibuza ukuba leliphi eli gama litsha. Ungoyiki. Namhlanje siza kuthetha ngale nto kunye namayeza anikwayo kwesi sifo. Masiziqonde ezi zinto ngokulula, njengokuthetha nomhlobo.
Yintoni i-Insulin Sensitivity?
Ngamafutshane, i-insulin yi-hormone ebaluleke kakhulu eveliswa sisitho emzimbeni wethu esibizwa ngokuba yi-pancreas. Xa iswekile (i-glucose) ekutyeni esikutyayo ingena egazini, yeyona nto inceda iswekile ingene kwiiseli zomzimba kwaye idale amandla.
Khawucinge ukuba iiseli emzimbeni wakho ziyiminyango, kwaye i-insulin sisitshixo esivula ezo ngcango.
- Ukuba novakalelo oluhle kwi-insulin kuthetha ukuba: Xa ufaka esi sitshixo (i-insulin), ucango (iseli) luvuleka lula. Iswekile egazini ingena lula kwiiseli kwaye iguqulwa ibe ngamandla.
- Ukuxhathisa i-insulin kuthetha ukuba: Eso sitshixo sinobunzima ekuvuleni ucango. Kufana nokuba ucango lubambekile. Ngoko ke ngenxa yokuba ucango alunakuvulwa, amanqanaba eswekile egazini ayanyuka. Emva koko i-pancreas iqala ukwenza i-insulin engakumbi, njengokuzisa izitshixo ezininzi ukuvula ucango olubambekileyo. Ekuhambeni kwexesha, le yiyo ebangela isifo seswekile (uhlobo lwesibini lwesifo seswekile).
Ngoko ke, into eyenziwa ngamayeza okuva i-insulin kukwenza loo minyango inamatheleyo ibe lula ukuyivula. Oko kukuthi, inceda i-insulin isebenze kakuhle.
Ngawaphi amayeza aphambili oku?
Eyona ndlela ilungileyo yokuphucula uvakalelo lwe-insulin kukutshintsha indlela yokuphila. Oku kuquka ukuzilolonga rhoqo, ukutya ukutya okunesondlo, kunye nokulawula ubunzima bakho. Nangona kunjalo, ugqirha wakho unokukunika amayeza kunye nezi zinto.
Kukho iindidi ezimbini eziphambili zamayeza.
1. I-Biguanides - Iyeza elilodwa kuphela kolu didi yiMetformin eyaziwayo.
2. I-Thiazolidinediones (TZDs) - Kukwakho namayeza kweli qela.
Ngoku makhe sijonge nganye kwezi ntlobo ngokwahlukeneyo.
I-Metformin, esiyaziyo sonke
I-Metformin lelona yeza lisetyenziswa kakhulu kwisifo seswekile sohlobo lwesibini emhlabeni. Ukuba unesifo seswekile, kusenokwenzeka ukuba usebenzisa eli yeza.
Isebenza njani i-metformin?
I-Metformin inceda ukulawula iswekile yegazi ngeendlela ezimbini eziphambili:
- Inciphisa ukuveliswa kweswekile sisibindi: Isibindi sethu sikwavelisa iswekile xa umzimba uyifuna. Ekubeni i-metformin ilawula le nkqubo, ubungakanani beswekile engafunekiyo eqokelelana egazini buyancipha.
- Ukwandisa uvakalelo lwe-insulin kwimisipha: Le yeyona nto ibalulekileyo. Iiseli zemisipha ziqala ukusabela kakuhle kwi-insulin. Emva koko iswekile egazini iya lula kwimisipha ize iguqulwe ibe ngamandla.
Izifundo zibonise ukuba ukuthatha i-metformin kunokunceda ukulibazisa ukuqala kwesifo seswekile kubantu abasengozini kwaye kukhusele kwiimeko ezifana nesifo sentliziyo.
| Ngokufutshane malunga neMetformin | |
|---|---|
| Idosi | Ugqirha wakho uza kugqiba idosi. Badla ngokuqala ngedosi ephantsi baze bayinyuse kancinci kancinci. Usenokuxelelwa ukuba uyithathe kanye okanye kabini ngemini xa usitya. |
| Iziphumo Eziqhelekileyo Ezingalindelekanga | Ukuphazamiseka kwesisu, isicaphucaphu, ukuhlanza, kwaye ingakumbi urhudo lunokubakho. Oku kudla ngokuphela kwiintsuku ezimbalwa njengoko umzimba uqhelana namayeza. Oku kunokunciphisa kakhulu ngokuthatha amayeza kunye nokutya. |
| Izinto ekufuneka uziqaphele | Eli yeza alifanelekanga ukuba unesifo sezintso esinzima . Kwakhona, imeko engaqhelekanga kodwa eyingozi ebizwa ngokuba yi-"lactic acidosis" inokubakho. Ukuba ufumana iimpawu ezifana nokuqaqamba kwemisipha, ukudinwa kakhulu, isicaphucaphu, kunye nokuphefumla ngokukhawuleza, yiya kwicandelo likaxakeka lesibhedlele (ETU) ngokukhawuleza. |
I-Metformin ayisoloko ibangela ukutyeba njengeminye imithi yesifo seswekile. Abanye abantu banokude banciphise umzimba.
I-Thiazolidinediones (ii-TZD)
Eli lelinye iqela lamayeza. La akwanyusa uvakalelo lwe-insulin. Kukho iintlobo ezimbini eziphambili zamayeza kweli qela: iPioglitazone kunye neRosiglitazone .
Oogqirha badla ngokucebisa i-metformin kuqala. Ukuba kunzima ukuyilawula okanye ngezinye izizathu, ungacinga ngolu hlobo lwamayeza e-TZD.
Kubaluleke kakhulu: Ukuba unesifo sentliziyo okanye ukhe wanesifo sentliziyo esibizwa ngokuba yi-congestive heart failure, la mayeza e-TZD awafanelekanga konke konke , kuba angenza imeko ibe mandundu.
| Uhlobo lweyeza | Izinto ekufuneka uzazi |
|---|---|
| I-Pioglitazone | Oku kwandisa uvakalelo lwe-insulin. Ezinye izifundo zibonise ukuba inokuba nefuthe kwisibindi, inyuse umngcipheko womhlaza wesinyi, kwaye inyuse umngcipheko wokuqhekeka kwamathambo. |
| I-Rosiglitazone | Oku kusebenza ngendlela efanayo naleyo iyeza lingasentla. Nangona kuye kwaphakanyiswa inkxalabo ngaphambili malunga nomngcipheko wesifo sentliziyo, izifundo zamva azikakuqinisekisi oku. Nangona kunjalo, kubalulekile ukuba uqaphele isifo sentliziyo xa usebenzisa la mayeza omabini. |
| Iziphumo ebezingalindelekanga eziqhelekileyo ze-TZDs | Iimpawu zingabandakanya ukutyeba, ukudumba ngenxa yokugcinwa kolwelo emzimbeni, iintlungu esifubeni, kunye nobunzima bokuphefumla. Ukuba ufumana naziphi na kwezi mpawu, qhagamshelana nogqirha wakho ngoko nangoko. |
Ukhetha njani amayeza afanelekileyo kuwe?
Lo ngumbuzo obaluleke kakhulu. Kodwa akuyomfuneko ukuba uwuphendule, ngugqirha wakho . Kuba uqwalasela izinto ezininzi xa ekhetha amayeza afanelekileyo kuwe.
- Injani isifo sakho seswekile?
- Ngaba unazo ezinye iingxaki zempilo (isifo sentliziyo, isifo sezintso, isifo sesibindi)?
- Uneminyaka emingaphi kwaye uphila ubomi obunjani?
- Zithini iziphumo ebezingalindelekanga kunye neenzuzo kunye nokungalungi kwamayeza?
Kusemva kokuqwalasela konke oku apho agqiba khona ukuba yeyiphi iyeza elifanelekileyo nelikhuselekileyo kunye nomlinganiselo walo kuwe.Ungaze usebenzise amayeza asetyenziswa ngumhlobo, okanye amayeza acetyiswa ngomnye umntu, ukuze uziphindezele.
Umyalezo Wokuya Ekhaya
- Ukumelana ne-insulin kuxa iiseli zomzimba wakho zingasabeli kakuhle kwi-insulin. Le yeyona nto ibangela isifo seswekile sohlobo lwesibini.
- Amayeza eMetformin kunye neTZD ngawona mayeza aphambili anceda ukwandisa uvakalelo lwe-insulin.
- Kubaluleke kakhulu njengamayeza, mhlawumbi nangakumbi, ukutya okufanelekileyo kunye nokuzilolonga rhoqo kubalulekile ekwandiseni uvakalelo lwe-insulin.
- Ngugqirha wakho kuphela onokukunika amayeza. Thatha idosi ayinikiweyo, kanye njengoko iyalelwe, nangexesha elifanelekileyo.
- Ngaphambi kokuba uqalise naliphi na iyeza elitsha, thetha ngokukhululekileyo nogqirha wakho malunga neenzuzo zalo, iingozi, kunye nemiphumo enokubakho. Musa ukoyika okanye uzive uneentloni. Lilungelo lakho.
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