Xa abantu becinga ngesifo seswekile, uninzi lwabantu lucinga ngenaliti ye-insulin. Abanye abantu bakufumanisa oku kuyoyikisa kwaye kuyacaphukisa kuba kufuneka bayitofe izihlandlo ezininzi ngemini. Kodwa ubusazi na ukuba ngoku kukho amayeza amaninzi amatsha, angengo-insulin, ajovayo esifo seswekile sohlobo lwesibini? Amanye ala mayeza kufuneka ajovwe kube kanye ngeveki. Ke namhlanje, masithethe ngokufutshane ngala mayeza matsha, aphucukileyo.
Yintoni le yeza? Isebenza njani?
Uhlobo oluphambili noludumileyo lwamayeza kolu didi lubizwa ngokuba yi -GLP-1 Receptor Agonists . Nangona igama lisenokuvakala liyinkimbinkimbi kancinci, indlela elisebenza ngayo ilula kakhulu.
Khawucinge nje, kukho ihomoni ebizwa ngokuba yi-"GLP-1" eveliswa ngokwemvelo emzimbeni wethu. Xa sisitya, le homoni ithumela umyalezo kwi-pancreas yethu, ithi, "Kulungile, ngoku iswekile iqokelelana egazini, ngoko ke velisa isixa esifunekayo se-insulin." Le nkqubo ibuthathaka kancinci kubantu abanesifo seswekile.
Oko kwenziwa ngala mayeza afakwayo esithetha ngawo namhlanje kukusebenza njenge-hormone yendalo kwaye anike olu phawu ngqo. Oko kukuthi:
- Inceda ipancreas ukuba ivelise i-insulin kuphela xa amanqanaba eswekile egazini enyuka .
- Ilawula ukuveliswa kweswekile ngokungeyomfuneko sisibindi.
- Iyanciphisa izinga lokugaya ukutya. Oku kukwenza uzive ugcwele nangona sele utye kancinci. Oku kunceda ekulawuleni ukutya kakhulu kwaye kunceda ekunciphiseni ubunzima .
Ngoku makhe sijonge iintlobo ezahlukeneyo zamayeza kolu didi.
| I-Dulaglutide (iTrulicity) | |
|---|---|
| Yintoni lento? | Eli liyeza le-GLP-1. Into ekhethekileyo kukuba kufuneka lifakwe kanye ngeveki . |
| Ngubani oza kuyithatha? | Oogqirha bayicebisa kubantu abadala abanesifo seswekile sohlobo lwesibini abangakwaziyo ukulawula iswekile yabo egazini kakuhle ngezinye iindlela zonyango. Ingasetyenziswa yodwa okanye kunye namanye amayeza eswekile (afana ne-metformin). |
| Iziphumo ebezingalindelekanga eziqhelekileyo | Isicaphucaphu, ukuhlanza, iintlungu zesisu, ukudumba, kunye nokuphelelwa ngumdla wokutya zinokwenzeka kwasekuqaleni. Uninzi lwexesha, ezi zinto ziyaphela kwiintsuku ezimbalwa. |
| I-Semaglutide (i-Ozempic) | |
|---|---|
| Yintoni lento? | Eli liyeza le-GLP-1 elidumileyo elithathwa kanye ngeveki . Abantu abaninzi eSri Lanka bayayazi ngegama elithi Ozempic. |
| Ngubani oza kuyithatha? | Inikwa abantu abadala abanesifo seswekile sohlobo lwesibini. Kufunyaniswe ukuba inezibonelelo ezongezelelweyo, ingakumbi kwabo basengozini enkulu yesifo sentliziyo okanye isifo sezintso. Oogqirha bakwacebisa ukuba inikwe abantu abatyebileyo kuba ikwanceda ekunciphiseni umzimba. |
| Iziphumo ebezingalindelekanga eziqhelekileyo | Ukucaphuka kancinci ukuya kokuphakathi, ukuphelelwa ngumdla wokutya, iintlungu zesisu, kwaye kwabanye abantu, iingxaki zamehlo (i-diabetic retinopathy) zinokwanda. Ngoko ke lumka xa uvavanya amehlo. |
| ITirzepatide (Mounjaro) | |
|---|---|
| Yintoni lento? | Eli liyeza elitsha neliphucukileyo. Lisebenza njenge-GLP-1 kunye nenye i-hormone ebizwa ngokuba yi-GIP. Ngoko ke liyeza 'elisebenza kabini' . Lithathwa kanye ngeveki. |
| Ngubani oza kuyithatha? | Inikwa abantu abadala abanesifo seswekile sohlobo lwesibini. Ibonisa iziphumo ezilungileyo kakhulu ekulawuleni iswekile egazini nasekunciphiseni ubunzima. |
| Iziphumo ebezingalindelekanga eziqhelekileyo | Njengamanye amayeza, isicaphucaphu, isisu esibuhlungu, ukungabi namdla wokutya, iintlungu zesisu, kunye nokuqhina kwesisu kunokwenzeka. |
Kubalulekile: Ulwazi olukhethekileyo malunga namayeza eklasi ye-GLP-1
Izifundo zezilwanyana zibonise unxulumano phakathi kwala mayeza kunye nomngcipheko okhulayo womhlaza we-thyroid kwizilwanyana, ezifana neempuku. Nangona kunjalo, akukacaci ukuba oku kuya kuba njalo na ebantwini . Nangona kunjalo, njengenyathelo lokukhusela, ukuba wena okanye umntu kusapho lwakho unembali yomhlaza we-thyroid, ngokuqinisekileyo kufuneka uxelele ugqirha wakho ngaphambi kokuba uqale eli yeza.
Elinye iyeza elisebenza ngendlela eyahlukileyo kancinci
Ukongeza kwiklasi ye-GLP-1, kukho olunye ugonyo olusebenza ngokwahlukileyo.
| IPramlintide (iSymlin) | |
|---|---|
| Yintoni lento? | Olu luhlobo lwehomoni oluyilwe yi-Amylin, eveliswa yipancreas yethu kunye ne-insulin. |
| Ngubani oza kuyithatha? | Oku kunikwa abantu abanesifo seswekile sohlobo loku-1 nohlobo lwesibini abasebenzisa i-insulin xa besitya . Isetyenziswa kunye ne-insulin. |
| Ingaba isebenza kanjani | Xa zithathwa kunye ne-insulin ngaphambi kokutya, zombini ezi zinto zisebenza kunye ukulawula iswekile egazini. Njengamanye amayeza, ziyacothisa ukugaywa kokutya kwaye zikwenze uzive ugcwele. |
| Iziphumo ebezingalindelekanga eziqhelekileyo | Isiphumo esiphambili sisicaphucaphu. Ukunciphisa oku, ugqirha uza kuqala ngedosi ephantsi aze anyuse idosi kancinci kancinci. Ukulahlekelwa ngumdla wokutya, ukuhlanza, ukudinwa, kunye nesiyezi nazo zinokubakho. |
Ukuba ucinga ngale yeza...
La mayeza aphucukile kakhulu kwaye ayasebenza. Kodwa awafanelekanga kuye wonke umntu. Ngugqirha wakho kuphela onokugqiba ukuba olu hlobo lwamayeza lukulungele na. Uza kukhetha unyango olufanelekileyo emva kokuqwalasela izinto ezininzi ezifana nemeko yakho yempilo, uhlobo lwesifo seswekile sakho, ubudala, kunye nezinye izifo.
Ingakumbi ukuba uceba ukukhulelwa okanye ukhulelwe okwangoku, ngokuqinisekileyo kufuneka wazise ugqirha wakho ngaphambi kokuba usebenzise naliphi na kula mayeza, njengoko kungekho zifundo zaneleyo malunga nendlela abachaphazela ngayo abafazi abakhulelweyo.
Umyalezo Wokuya Ekhaya
- Ayizizo zonke iinaliti zesifo seswekile ezisebenzisa i-insulin. Ngoku kukho amayeza aphucukileyo athathwa kanye ngeveki, afana ne-Ozempic kunye ne-Trulicity.
- La mayeza awagcini nje ngokulawula iswekile egazini, kodwa anokukunceda unciphise umzimba ngokukwenza uzive ugcwele.
- Iziphumo ezingezizo ezifana nokucaphuka, ukuhlanza, kunye nokuphelelwa ngumdla ziqhelekile xa uqala ukuthatha eli yeza. Uninzi lwexesha, ziyaphela emva kweentsuku ezimbalwa. Kodwa ukuba ziyaqhubeka okanye zinzima, xelela ugqirha wakho.
- Ngaphambi kokuba uqalise naluphi na unyango olutsha, qiniseka ukuba uxelela ugqirha wakho ngeemeko zakho zonyango zangoku kunye nembali yezonyango zosapho (ingakumbi umhlaza we-thyroid).
- Musa ukugqiba ukuba eli yeza likulungele na ngokujonga kwi-intanethi. Ngugqirha okuxilongayo kuphela omele enze eso sigqibo.
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