Ngaba umntwana wakho une-'Neuroblastoma'? Masifunde ngesitofu sokugonya se-'Dinutuximab'!

Ndiyaqonda ukuba kunzima kangakanani ukwazi ukuba umntwana wakho unesifo esifana ne-'Neuroblastoma'. Ngexesha elinjalo, kufika imibuzo eliwaka engqondweni, kwaye uzive ulusizi kwaye usoyika. Kodwa khumbula, isayensi yezonyango iphucuke kakhulu kule mihla. Ngoko ke, kukho unyango olunokunikwa kwiimeko ezinjalo. Elinye lamayeza akhethekileyo yi-'Dinutuximab'. Namhlanje, siza kuthetha nje ngesi sitofu se-'Dinutuximab', indlela yokusinika umntwana, kunye nezinto ekufuneka uzilumkele.

Loluphi uhlobo lweyeza elithi `Dinutuximab`?

Ngamafutshane, i-'Dinutuximab' liyeza elikwiqela elikhethekileyo lamayeza abizwa ngokuba yi -'Monoclonal Antibody' . Cinga ngayo, asinayo na inkqubo yomzimba yokulwa nezifo emizimbeni yethu? Ngokufanayo, le 'Monoclonal Antibody' ikwayiproteni eyenziwe ngokukodwa kwilebhu. Ingcali yale ngxaki kukuba yenzelwe ukujolisa ngqo nokuhlasela iiseli ezithile, ezifana neeseli zomhlaza. I-'Dinutuximab' isetyenziselwa ngokukodwa ukunyanga uhlobo lomhlaza olubizwa ngokuba yi-'Neuroblastoma', oluvela ebantwaneni .

Ungalibona eli yeza phantsi kwegama lophawu elithi `Unituxin`. Eli asiloyeza eliqhelekileyo, kodwa liyeza elinamandla kakhulu elinikwa phantsi kweliso loogqirha abaziingcali. Kungoko ke, kubaluleke kakhulu ukuba nokuqonda kakuhle oku.

Kuphantsi kweziphi iimeko apho eli yeza linikwa abantwana?

Njengoko benditshilo ngaphambili, i-'Dinutuximab' isetyenziswa kakhulu ukunyanga umhlaza obizwa ngokuba yi-'Neuroblastoma' owenzeka kubantwana abancinci, oko kukuthi, abantwana abaneminyaka eli-1 ubudala . I-'Neuroblastoma' luhlobo lomhlaza owenzeka kwinkqubo yemithambo-luvo. Ngumhlaza oqhele ukubonwa ebantwaneni.

Ngamanye amaxesha, oogqirha banokugqiba ekubeni basebenzise eli yeza kwezinye iimeko zonyango. Kodwa ngugqirha kuphela onokugqiba emva kokuba ehlolisise ngononophelo imeko yomntwana wakho. Ngoko ke, buza ugqirha wakho okanye ikhemisti yakho nayiphi na imibuzo onokuba nayo malunga nokusebenzisa eli yeza.

Zeziphi izinto ezibalulekileyo ekufuneka uzixelele ugqirha ngaphambi kokuba uqale ukusebenzisa amayeza?

Oku kubaluleke kakhulu. Ngaphambi kokuba uqale unyango lwe-'Dinutuximab', kubalulekile ukwazisa iqela lezonyango ngolwazi oluthile malunga nemeko yempilo yomntwana wakho. Kuba impumelelo kunye nokhuseleko lonyango luxhomekeke kolo lwazi.

Nazi ezinye izinto onokuzithetha ngokuqinisekileyo:

• Usulelo lwangoku: Ukuba umntwana okwangoku unesulelo, njengomkhuhlane okanye umkhuhlane.
• Isifo sezintso: Ukuba umntwana uneengxaki ezinxulumene nezintso.
• Isifo sesibindi: Ukuba unayo nayiphi na imeko enxulumene nesibindi.
• Inani eliphantsi leeseli zegazi: Oku kuthetha inani eliphantsi leeseli ezimhlophe zegazi, iiseli ezibomvu zegazi, okanye iiplatelets.Ukuba sele ufunyenwe unale meko, xa ezi zinto zinciphile, usulelo kunye nokopha kunokuvela ngokulula.
• Isifo semiphunga okanye sokuphefumla: Iimeko ezinje ngobunzima bokuphefumla, i-asthma.
• Ukukhulelwa: Nokuba umntwana usebenzisa eli yeza, umntu othatha eli yeza (umz. umama) kufuneka aziswe ukuba ukhulelwe okanye ucinga ukuba ukhulelwe (ingakumbi xa ucinga ngemeko-bume kunye nendlela eliphathwa ngayo eli yeza). (Oku akubhekiseli kumntwana okhulelwayo, kodwa kunokuba kubalulekile ukukhankanya umama okanye umnakekeli. Okanye, ukuba intombazana encinci isebenzisa eli yeza, oku kufanele kuxoxwe ngako ngokukodwa. Kwinqaku lokuqala, "Musa ukukhulelwa ngelixa usebenzisa eli yeza" kubhekisele kumntu othatha eli yeza.) Ngokukodwa, ukuba intombi yakho isebenzisa eli yeza, ukuba ikhulelwe, iceba ukukhulelwa, okanye ukuba ukrokrela ukuba ikhulelwe, kufuneka uxelele ugqirha wakho ngoko nangoko.
• Ukuncancisa: Ukuba uncancisa umntwana wakho. (Oku kukwasebenza nasekuncanciseni umntwana wakho ukuba ungumama osebenzisa eli yeza.)
• I-allergy reaction: Ukuba umntwana wakho une-allergy kwi-Dinutuximab, naluphi na olunye unyango, ukutya, iidayi, okanye izithinteli, kubalulekile ukubazisa .

Ukuxelela ugqirha ngezi zinto ngaphandle kokuzifihla kubaluleke kakhulu kukhuseleko lomntwana.

Umnika njani umntwana eli yeza?

I-'Dinutuximab' ayiloyeza olithatha ekhaya njengepilisi. Inikwa umntwana njenge-'infusion' emthanjeni . Kufana nokumnika i-saline.

Olu nyango lunikwa esibhedlele okanye ekliniki ngugqirha okanye umongikazi oqeqeshiweyo . Ngoko ke baya kumjonga ngokusondeleyo umntwana wakho xa enikwa eli yeza. Eli asiloyeza onokulithatha uye nalo ekhaya.

Thetha nogqirha wezingane malunga nokunika umntwana wakho eli yeza. Kwezinye iimeko ezikhethiweyo, eli yeza linokunikwa abantwana abaneminyaka eli-1 ubudala . Nangona kunjalo, kukho amanyathelo akhethekileyo okhuseleko kunye neenkxalabo.

Yintoni omawuyenze ukuba umthamo weyeza unyusiwe?

Kwiimeko ezingaqhelekanga, ukuba ucinga ukuba umntwana wakho unikwe eli yeza lininzi kakhulu, fowunela iziko lokulawula ityhefu okanye igumbi likaxakeka esibhedlele ngoko nangoko . Musa ukuchitha ixesha.

Kubalulekile: Eli yeza limiselwe umntwana wakho kuphela. Musa ukunika omnye umntu eli yeza nangasiphi na isizathu .

Kuthekani ukuba ndiphoswa yintlanganiso yamayeza?

Kubaluleke kakhulu ukunika amayeza ngexesha kwaye ungaliphosi ixesha elibekiweyo. Ukuba ngesizathu esithile awukwazi ukuya esibhedlele/eklinikhi ukuze unike umntwana wakho amayeza ngosuku olubekiweyo, fowunela ugqirha wakho okanye ingcali yezempilo ngokukhawuleza uze umxelele.Emva koko baza kukuxelela into omawuyenze ngokulandelayo.

Ngaba eli yeza lingadibana namanye amayeza?

Unxibelelwano phakathi kwe-dinutuximab kunye namanye amayeza umntwana wakho asenokuba uwasebenzisa alukafundwa ngokupheleleyo. Oku kuthetha ukuba kukho ithuba lokuba amanye amayeza angabangela iingxaki xa esetyenziswa kunye nayo.

Ngoko ke, nika ugqirha wakho uluhlu olupheleleyo lwamayeza asetyenziswa ngumntwana wakho, kuquka iivithamini, imifuno, amayeza angagunyaziswanga ngugqirha, kunye nezongezo zokutya. Kwakhona, mxelele umntwana wakho (ukuba ungumntu omdala) ukuba uyatshaya , usela utywala, okanye usebenzisa ezinye iziyobisi. Ezinye izinto zinokuchaphazela eli yeza.

Yintoni ekufuneka uyiqwalasele ngokukodwa xa unika amayeza?

Umntwana wakho angaziva engaphili kakuhle okanye engaphili kakuhle xa esela eli yeza. Oku kungaba yinto eqhelekileyo okanye kungaba luphawu lwesiphumo esingalindelekanga. Ke ngoko, ukuba ubona naziphi na iimpawu ezintsha okanye utshintsho, xelela ugqirha wakho . Kufuneka uqhubeke nokusela iyeza njengoko kuyalelwe, nokuba uzive ungaphili kakuhle, de ugqirha wakho akuxelele ukuba uyeke.

Nika ingqalelo ekhethekileyo kwezi zinto:

• Utshintsho embonweni: Ukuba umntwana wakho ubona luzizi, unengxaki yokubona ekukhanyeni okuqaqambileyo, okanye ubona naluphi na utshintsho embonweni , xelela ugqirha wakho ngoko nangoko .
• Iimpendulo ezinzulu ze-allergy: Eli yeza ngamanye amaxesha linokubangela iimpembelelo ezinzulu ze-allergy. Ukunciphisa lo mngcipheko, oogqirha baya kunika umntwana wakho amanye amayeza ngaphambi kokuba anike iDinutuximab. Nika umntwana wakho iyeza kanye njengoko kuyalelwe.
• Iimpawu zosulelo: Ukuba umntwana wakho unomkhuhlane, ukubanda, okanye ezinye iimpawu zomkhuhlane, ezifana nomphimbo obuhlungu, ukukhohlela, okanye impumlo egobhozayo , tsalela umnxeba ugqirha wakho ngoko nangoko . Musa ukuzinyanga. Eli yeza linokunciphisa amandla omntwana wakho okulwa nosulelo. Ngoko ke, zama ukugcina umntwana wakho kude nabantu abagulayo kangangoko kunokwenzeka .
• Ukukhulelwa (kwabasetyhini abaselula): Ukuba ungumfazi oselula othatha eli yeza, kufuneka uphephe ukukhulelwa ngelixa usela iyeza kwaye kangangeenyanga ezimbini emva kokuyeka iyeza . Ukuba uceba ukukhulelwa okanye ukrokrela ukuba ukhulelwe, xelela ugqirha wakho ngoko nangoko. Eli yeza linokubangela iziphumo ebezingalindelekanga ezibi kakhulu kusana olungekazalwa. Buza ugqirha wakho okanye ikhemisti ngolwazi oluthe kratya.
• Ukuncancisa: Musa ukuncancisa umntwana wakho ngelixa usebenzisa eli yeza.

Zithini iziphumo ebezingalindelekanga ezinokubakho zale yeza?

Njengazo zonke iziyobisi, iDinutuximab inokubangela ezinye iziphumo ebezingalindelekanga. Ezinye zazo kufuneka zixelwe kugqirha wakho ngoko nangoko. Ezinye zazo azisoloko zimbi kakhulu, kodwa ukuba ziyaqhubeka kwaye ziyakhathaza, kufuneka uxelele ugqirha wakho .

Iziphumo ebezingalindelekanga ekufuneka zixelwe kugqirha wakho okanye kwingcali yezempilo ngoko nangoko:

• Iimpendulo ze-allergy: Ukurhawuzelela kwesikhumba, ukurhawuzelela, iimeko ezifana ne-eczema, ukudumba kobuso, imilebe, okanye ulwimi.
• Igazi kumchamo.
• Utshintsho embonweni: Ukubona okufipheleyo, ukuva ukukhanya (ubunzima bokubona).
• Ukubalwa kwegazi okuphantsi: Eli yeza linokubangela ukwehla kwenani leeseli ezimhlophe zegazi, iiseli ezibomvu zegazi, kunye neeplatelets. Oku kunokunyusa umngcipheko wosulelo kunye nokopha.
• Intlungu, ukurhawuzelela, ukungaziva mnandi ezandleni okanye ezinyaweni.
• Ukuxhuzula.
• Intloko ebuhlungu kakhulu.
• Iimpawu zosulelo: umkhuhlane okanye ukubanda, ukukhohlela, umphimbo obuhlungu.
• Iimpawu zoxinzelelo lwegazi oluphantsi: isiyezi, ukuphelelwa ngamandla, ukuphelelwa ngamandla, ukudinwa okanye ubuthathaka obungaqhelekanga.
• Iimpawu ze-potassium ephantsi: ukuxhuzula okanye ukuqaqanjelwa yimisipha, iintlungu zesifuba, isiyezi, ukuquleka, ubunzima bokuphefumla, ukubetha kwentliziyo okukhawulezayo okanye okungahambelaniyo.
• Ukudumba kwamaqatha, iinyawo, izandla.
• Ukudinwa okugqithisileyo (`ukudinwa`).
• Ubunzima bokuchama okanye ukutshintsha ubungakanani bomchamo.
• Ukutyeba kwakho.

Iziphumo ebezingalindelekanga ezingadingi ngcebiso kagqirha, kodwa kufuneka zixelwe kugqirha wakho ukuba ziyaqhubeka okanye ziyakhathaza:

• Urhudo.
• Ukulahlekelwa yintliziyo.
• Ukuhlanza.

Kubalulekile: Olu luhlu alubandakanyi zonke iziphumo ebezingalindelekanga. Ukuba umntwana wakho ufumana ezinye iimpawu, nceda udibane nogqirha wakho.

Uligcina njani eli yeza?

Akunyanzelekanga ukuba ukhathazeke ngale nto. Ekubeni i-'Dinutuximab' iliyeza elinikwa esibhedlele okanye eklinikhi, akufuneki ulithathe uliyise ekhaya uligcine. Ngoko ke akufuneki ukhathazeke ngokuba iyeza liza konakala okanye lingene ezandleni zabantwana bakho.

Okokugqibela, izinto ekufuneka uzikhumbule (Umyalezo Wokuya Ekhaya)

I-'Dinutuximab' liyeza elibaluleke kakhulu nelinamandla elinikwa imeko yomhlaza enzima efana ne-'Neuroblastoma'. Ngexesha lonyango, kufuneka uqaphele kakhulu ngomntwana. Njengokuba oogqirha nabahlengikazi behlala bejonga imeko yomntwana, kubaluleke kakhulu kuni, njengabazali, ukuba niqaphele utshintsho lomntwana kunye nemiphumo emibi.

• Ukuba ubona naluphi na utshintsho okanye iinkxalabo ezincinci, xelela ugqirha wakho ngoko nangoko. Musa ukuba neentloni okanye ungayinaki into yokuba yinto encinci.
• Landela imiyalelo kagqirha wakho ngokuchanekileyo. Ungaphoswa kutyelelo lwamayeza okanye ukuhlolwa.
• Yiba nesibindi. Olu hambo aluyiyo yodwa odlula kuyo. Oogqirha, abahlengikazi, usapho, kunye nabahlobo bonke bakunye nawe.

Ndiyathemba ukuba olu lwazi lukuncedile ukuba uqonde kakuhle eli yeza. Ndinqwenela umntwana wakho aphile ngokukhawuleza!

I- Dinutuximab, i-Neuroblastoma, umhlaza, umhlaza wabantwana, i-antibody ye-monoclonal, i-vaccine, iziphumo ebezingalindelekanga